Works matching IS 07248741 AND DT 2022 AND VI 39 AND IP 7

Results: 26

Pharmacokinetics and Pharmacodynamic Effect of a Blood-Brain Barrier-Crossing Fusion Protein Therapeutic for Alzheimer's Disease in Rat and Dog.
Published in:
Pharmaceutical Research, 2022, v. 39, n. 7, p. 1497, doi. 10.1007/s11095-022-03285-z
By:
- Lessard, Etienne;
- Rennie, Kerry;
- Haqqani, Arsalan;
- Ling, Binbing;
- Whitfield, James;
- Paradis, Andrea;
- Araujo, Joseph;
- Yoganathan, Nathan;
- Gillard, John;
- Stanimirovic, Danica;
- Chakravarthy, Balu
Publication type:
Article
Transferrin Receptor Binding BBB-Shuttle Facilitates Brain Delivery of Anti-Aβ-Affibodies.
Published in:
Pharmaceutical Research, 2022, v. 39, n. 7, p. 1509, doi. 10.1007/s11095-022-03282-2
By:
- Faresjö, Rebecca;
- Lindberg, Hanna;
- Ståhl, Stefan;
- Löfblom, John;
- Syvänen, Stina;
- Sehlin, Dag
Publication type:
Article
Drug Distribution in Brain and Cerebrospinal Fluids in Relation to IC<sub>50</sub> Values in Aging and Alzheimer's Disease, Using the Physiologically Based LeiCNS-PK3.0 Model.
Published in:
Pharmaceutical Research, 2022, v. 39, n. 7, p. 1303, doi. 10.1007/s11095-022-03281-3
By:
- Saleh, Mohammed A. A.;
- Bloemberg, Julia S.;
- Elassaiss-Schaap, Jeroen;
- de Lange, Elizabeth C. M.
Publication type:
Article
Professor Margareta Hammarlund-Udenaes - Humbled Scientist Shaping Modern Neuropharmacokinetics.
Published in:
Pharmaceutical Research, 2022, v. 39, n. 7, p. 1283, doi. 10.1007/s11095-022-03279-x
By:
- Loryan, Irena;
- Smith, David E.;
- Artursson, Per;
- Breimer, Douwe;
- Deguchi, Yoshiharu;
- Paalzow, Lennart;
- Sugiyama, Yuichi;
- Terasaki, Tetsuya;
- de Lange, Elizabeth C. M.
Publication type:
Article
Professor Margareta Hammarlund-Udenaes – a Modern and Visionary Mentor.
Published in:
Pharmaceutical Research, 2022, v. 39, n. 7, p. 1291, doi. 10.1007/s11095-022-03278-y
By:
- Syvänen, Stina;
- Fridén, Markus
Publication type:
Article
Targeting Transporters for Drug Delivery to the Brain: Can We Do Better?
Published in:
Pharmaceutical Research, 2022, v. 39, n. 7, p. 1415, doi. 10.1007/s11095-022-03241-x
By:
- Puris, Elena;
- Fricker, Gert;
- Gynther, Mikko
Publication type:
Article
Correction: In Vitro—In Vivo Extrapolation of Hepatic Clearance in Preclinical Species.
Published in:
2022
By:
- Tess, David A.;
- Ryu, Sangwoo;
- Di, Li
Publication type:
Correction Notice
To Measure is to Know: A Perspective on the Work of Dr. Margareta Hammarlund-Udenaes.
Published in:
Pharmaceutical Research, 2022, v. 39, n. 7, p. 1297, doi. 10.1007/s11095-022-03225-x
By:
- Griffith, Jessica I.;
- Elmquist, William F.
Publication type:
Article
PET Imaging in Preclinical Anti-Aβ Drug Development.
Published in:
Pharmaceutical Research, 2022, v. 39, n. 7, p. 1481, doi. 10.1007/s11095-022-03277-z
By:
- Syvänen, Stina;
- Meier, Silvio R.;
- Roshanbin, Sahar;
- Xiong, Mengfei;
- Faresjö, Rebecca;
- Gustavsson, Tobias;
- Bonvicini, Gillian;
- Schlein, Eva;
- Aguilar, Ximena;
- Julku, Ulrika;
- Eriksson, Jonas;
- Sehlin, Dag
Publication type:
Article
Regional Differences in the Absolute Abundance of Transporters, Receptors and Tight Junction Molecules at the Blood-Arachnoid Barrier and Blood-Spinal Cord Barrier among Cervical, Thoracic and Lumbar Spines in Dogs.
Published in:
Pharmaceutical Research, 2022, v. 39, n. 7, p. 1393, doi. 10.1007/s11095-022-03275-1
By:
- Takeuchi, Hina;
- Suzuki, Masayoshi;
- Goto, Ryohei;
- Tezuka, Kenta;
- Fuchs, Holger;
- Ishiguro, Naoki;
- Terasaki, Tetsuya;
- Braun, Clemens;
- Uchida, Yasuo
Publication type:
Article
Shedding Light on the Blood–Brain Barrier Transport with Two-Photon Microscopy In Vivo.
Published in:
Pharmaceutical Research, 2022, v. 39, n. 7, p. 1457, doi. 10.1007/s11095-022-03266-2
By:
- Kucharz, Krzysztof;
- Kutuzov, Nikolay;
- Zhukov, Oleg;
- Mathiesen Janiurek, Mette;
- Lauritzen, Martin
Publication type:
Article
Correction to: Construction and Functional Evaluation of a Three-Dimensional Blood–Brain Barrier Model Equipped With Human Induced Pluripotent Stem Cell-Derived Brain Microvascular Endothelial Cells.
Published in:
2022
By:
- Kurosawa, Toshiki;
- Sako, Daiki;
- Tega, Yuma;
- Debori, Yasuyuki;
- Tomihara, Yumi;
- Aoyama, Kazunobu;
- Kubo, Yoshiyuki;
- Amano, Nobuyuki;
- Deguchi, Yoshiharu
Publication type:
Correction Notice
Unbound Brain-to-Plasma Partition Coefficient, K<sub>p,uu,brain</sub>—a Game Changing Parameter for CNS Drug Discovery and Development.
Published in:
Pharmaceutical Research, 2022, v. 39, n. 7, p. 1321, doi. 10.1007/s11095-022-03246-6
By:
- Loryan, Irena;
- Reichel, Andreas;
- Feng, Bo;
- Bundgaard, Christoffer;
- Shaffer, Christopher;
- Kalvass, Cory;
- Bednarczyk, Dallas;
- Morrison, Denise;
- Lesuisse, Dominique;
- Hoppe, Edmund;
- Terstappen, Georg C.;
- Fischer, Holger;
- Di, Li;
- Colclough, Nicola;
- Summerfield, Scott;
- Buckley, Stephen T.;
- Maurer, Tristan S.;
- Fridén, Markus
Publication type:
Article
Construction and Functional Evaluation of a Three-Dimensional Blood–Brain Barrier Model Equipped With Human Induced Pluripotent Stem Cell-Derived Brain Microvascular Endothelial Cells.
Published in:
Pharmaceutical Research, 2022, v. 39, n. 7, p. 1535, doi. 10.1007/s11095-022-03249-3
By:
- Kurosawa, Toshiki;
- Sako, Daiki;
- Tega, Yuma;
- Debori, Yasuyuki;
- Tomihara, Yumi;
- Aoyama, Kazunobu;
- Kubo, Yoshiyuki;
- Amano, Nobuyuki;
- Deguchi, Yoshiharu
Publication type:
Article
Evaluation of Blood-CSF Barrier Transport by Quantitative Real Time Fluorescence Microscopy.
Published in:
Pharmaceutical Research, 2022, v. 39, n. 7, p. 1469, doi. 10.1007/s11095-022-03251-9
By:
- Sun, Austin;
- Wang, Joanne
Publication type:
Article
Characterization of Aripiprazole Uptake Transporter in the Blood-Brain Barrier Model hCMEC/D3 Cells by Targeted siRNA Screening.
Published in:
Pharmaceutical Research, 2022, v. 39, n. 7, p. 1549, doi. 10.1007/s11095-022-03223-z
By:
- Kadoguchi, Moeno;
- Arakawa, Hiroshi;
- Honda, Ryokichi;
- Hotta, Kazuki;
- Shirasaka, Yoshiyuki;
- Deguchi, Yoshiharu;
- Tamai, Ikumi
Publication type:
Article
In-Vivo and Ex-Vivo Brain Uptake Studies of Peptidomimetic Neurolysin Activators in Healthy and Stroke Animals.
Published in:
Pharmaceutical Research, 2022, v. 39, n. 7, p. 1587, doi. 10.1007/s11095-022-03218-w
By:
- Nozohouri, Saeideh;
- Esfahani, Shiva Hadi;
- Noorani, Behnam;
- Patel, Dhaval;
- Villalba, Heidi;
- Ghanwatkar, Yashwardhan;
- Rahman, Md. Shafikur;
- Zhang, Yong;
- Bickel, Ulrich;
- Trippier, Paul C.;
- Karamyan, Vardan T.;
- Abbruscato, Thomas J.
Publication type:
Article
In Vitro - in Vivo Extrapolation of Hepatic Clearance in Preclinical Species.
Published in:
Pharmaceutical Research, 2022, v. 39, n. 7, p. 1615, doi. 10.1007/s11095-022-03205-1
By:
- Tess, David A.;
- Ryu, Sangwoo;
- Di, Li
Publication type:
Article
Population Pharmacokinetics of Flucloxacillin In Bone and Soft Tissue– Standard Dosing is Not Sufficient to Achieve Therapeutic Concentrations.
Published in:
Pharmaceutical Research, 2022, v. 39, n. 7, p. 1633, doi. 10.1007/s11095-022-03197-y
By:
- Öbrink-Hansen, Kristina;
- Pham, Anh Duc;
- Bue, Mats;
- Hanberg, Pelle;
- Bendtsen, Mathias;
- Slater, Josefine;
- Friberg, Lena E.;
- Thorsted, Anders;
- Stilling, Maiken
Publication type:
Article
Pharmacoproteomics of Brain Barrier Transporters and Substrate Design for the Brain Targeted Drug Delivery.
Published in:
Pharmaceutical Research, 2022, v. 39, n. 7, p. 1363, doi. 10.1007/s11095-022-03193-2
By:
- Huttunen, Kristiina M.;
- Terasaki, Tetsuya;
- Urtti, Arto;
- Montaser, Ahmed B.;
- Uchida, Yasuo
Publication type:
Article
In Vitro-In Vivo Correlation of Blood–Brain Barrier Permeability of Drugs: A Feasibility Study Towards Development of Prediction Methods for Brain Drug Concentration in Humans.
Published in:
Pharmaceutical Research, 2022, v. 39, n. 7, p. 1575, doi. 10.1007/s11095-022-03189-y
By:
- Ito, Ryo;
- Morio, Hanae;
- Baba, Tomoyo;
- Sakaguchi, Yasuyuki;
- Wakayama, Naomi;
- Isogai, Ryuto;
- Yamaura, Yoshiyuki;
- Komori, Takafumi;
- Furihata, Tomomi
Publication type:
Article
Antibody-Targeted Liposomes for Enhanced Targeting of the Blood-Brain Barrier.
Published in:
Pharmaceutical Research, 2022, v. 39, n. 7, p. 1523, doi. 10.1007/s11095-022-03186-1
By:
- Ye, Zhou;
- Gastfriend, Benjamin D.;
- Umlauf, Benjamin J.;
- Lynn, David M.;
- Shusta, Eric V.
Publication type:
Article
High Throughput Screening of a Prescription Drug Library for Inhibitors of Organic Cation Transporter 3, OCT3.
Published in:
Pharmaceutical Research, 2022, v. 39, n. 7, p. 1599, doi. 10.1007/s11095-022-03171-8
By:
- Chen, Eugene C.;
- Matsson, Pär;
- Azimi, Mina;
- Zhou, Xujia;
- Handin, Niklas;
- Yee, Sook Wah;
- Artursson, Per;
- Giacomini, Kathleen M.
Publication type:
Article
Limited Impact of Murine Placental MDR1 on Fetal Exposure of Certain Drugs Explained by Bypass Transfer Between Adjacent Syncytiotrophoblast Layers.
Published in:
Pharmaceutical Research, 2022, v. 39, n. 7, p. 1645, doi. 10.1007/s11095-022-03165-6
By:
- Fujita, Arimi;
- Noguchi, Saki;
- Hamada, Rika;
- Inoue, Satoko;
- Shimada, Tsutomu;
- Katakura, Satomi;
- Maruyama, Tetsuo;
- Sai, Yoshimichi;
- Nishimura, Tomohiro;
- Tomi, Masatoshi
Publication type:
Article
The Extension of the LeiCNS-PK3.0 Model in Combination with the "Handshake" Approach to Understand Brain Tumor Pathophysiology.
Published in:
Pharmaceutical Research, 2022, v. 39, n. 7, p. 1343, doi. 10.1007/s11095-021-03154-1
By:
- Hirasawa, Makoto;
- Saleh, Mohammed A. A.;
- de Lange, Elizabeth C. M.
Publication type:
Article
Effect of Insulin Receptor-Knockdown on the Expression Levels of Blood–Brain Barrier Functional Proteins in Human Brain Microvascular Endothelial Cells.
Published in:
Pharmaceutical Research, 2022, v. 39, n. 7, p. 1561, doi. 10.1007/s11095-021-03131-8
By:
- Nagano, Hinako;
- Ito, Shingo;
- Masuda, Takeshi;
- Ohtsuki, Sumio
Publication type:
Article