Works matching IS 03643190 AND DT 2014 AND VI 39 AND IP 10

Results: 17

Analogues of 3-Hydroxyisoxazole-Containing Glutamate Receptor Ligands Based on the 3-Hydroxypyrazole-Moiety: Design, Synthesis and Pharmacological Characterization.

Published in:

Neurochemical Research, 2014, v. 39, n. 10, p. 1895, doi. 10.1007/s11064-014-1332-0

By:

Jørgensen, Lars;
Nielsen, Birgitte;
Pickering, Darryl;
Kristensen, Anders;
Frydenvang, Karla;
Madsen, Ulf;
Clausen, Rasmus

Publication type:

Article

mGluR5: Exploration of Orthosteric and Allosteric Ligand Binding Pockets and Their Applications to Drug Discovery.

Published in:

Neurochemical Research, 2014, v. 39, n. 10, p. 1862, doi. 10.1007/s11064-014-1248-8

By:

Mølck, Christina;
Harpsøe, Kasper;
Gloriam, David;
Mathiesen, Jesper;
Nielsen, Søren;
Bräuner-Osborne, Hans

Publication type:

Article

Multi-target Design Strategies in the Context of Alzheimer's Disease: Acetylcholinesterase Inhibition and NMDA Receptor Antagonism as the Driving Forces.

Published in:

Neurochemical Research, 2014, v. 39, n. 10, p. 1914, doi. 10.1007/s11064-014-1250-1

By:

Rosini, Michela;
Simoni, Elena;
Minarini, Anna;
Melchiorre, Carlo

Publication type:

Article

Correlating the Metabolic Stability of Psychedelic 5-HT Agonists with Anecdotal Reports of Human Oral Bioavailability.

Published in:

Neurochemical Research, 2014, v. 39, n. 10, p. 2018, doi. 10.1007/s11064-014-1253-y

By:

Leth-Petersen, Sebastian;
Bundgaard, Christoffer;
Hansen, Martin;
Carnerup, Martin;
Kehler, Jan;
Kristensen, Jesper

Publication type:

Article

GABA Pharmacology: The Search for Analgesics.

Published in:

Neurochemical Research, 2014, v. 39, n. 10, p. 1948, doi. 10.1007/s11064-014-1254-x

By:

McCarson, Kenneth;
Enna, S.

Publication type:

Article

The GABA Synapse as a Target for Antiepileptic Drugs: A Historical Overview Focused on GABA Transporters.

Published in:

Neurochemical Research, 2014, v. 39, n. 10, p. 1980, doi. 10.1007/s11064-014-1263-9

By:

Schousboe, Arne;
Madsen, Karsten;
Barker-Haliski, Melissa;
White, H.

Publication type:

Article

Probing for Improved Potency and In Vivo Bioavailability of Excitatory Amino Acid Transporter Subtype 1 Inhibitors UCPH-101 and UCPH-102: Design, Synthesis and Pharmacological Evaluation of Substituted 7-Biphenyl Analogs.

Published in:

Neurochemical Research, 2014, v. 39, n. 10, p. 1964, doi. 10.1007/s11064-014-1264-8

By:

Erichsen, Mette;
Hansen, Jeanette;
Ruiz, Josep;
Demmer, Charles;
Abrahamsen, Bjarke;
Bastlund, Jesper;
Bundgaard, Christoffer;
Jensen, Anders;
Bunch, Lennart

Publication type:

Article

On the Discovery and Development of Pimavanserin: A Novel Drug Candidate for Parkinson's Psychosis.

Published in:

Neurochemical Research, 2014, v. 39, n. 10, p. 2008, doi. 10.1007/s11064-014-1293-3

By:

Hacksell, Uli;
Burstein, Ethan;
McFarland, Krista;
Mills, Roger;
Williams, Hilde

Publication type:

Article

Revision of the Classical Dopamine D Agonist Pharmacophore Based on an Integrated Medicinal Chemistry, Homology Modelling and Computational Docking Approach.

Published in:

Neurochemical Research, 2014, v. 39, n. 10, p. 1997, doi. 10.1007/s11064-014-1314-2

By:

Krogsgaard-Larsen, N.;
Harpsøe, K.;
Kehler, J.;
Christoffersen, C.;
Brøsen, P.;
Balle, T.

Publication type:

Article

Inhibition of AMPA Receptors by Polyamine Toxins is Regulated by Agonist Efficacy and Stargazin.

Published in:

Neurochemical Research, 2014, v. 39, n. 10, p. 1906, doi. 10.1007/s11064-014-1258-6

By:

Poulsen, Mette;
Lucas, Simon;
Strømgaard, Kristian;
Kristensen, Anders

Publication type:

Article

Pharmacological Identification of a Guanidine-Containing β-Alanine Analogue with Low Micromolar Potency and Selectivity for the Betaine/GABA Transporter 1 (BGT1).

Published in:

Neurochemical Research, 2014, v. 39, n. 10, p. 1988, doi. 10.1007/s11064-014-1336-9

By:

Al-Khawaja, Anas;
Petersen, Jette;
Damgaard, Maria;
Jensen, Mette;
Vogensen, Stine;
Lie, Maria;
Kragholm, Bolette;
Bräuner-Osborne, Hans;
Clausen, Rasmus;
Frølund, Bente;
Wellendorph, Petrine

Publication type:

Article

Analysis of γ-Aminobutyric Acid (GABA) Type A Receptor Subtypes Using Isosteric and Allosteric Ligands.

Published in:

Neurochemical Research, 2014, v. 39, n. 10, p. 1924, doi. 10.1007/s11064-014-1382-3

By:

Olsen, Richard

Publication type:

Article

The Receptor Concept in 3D: From Hypothesis and Metaphor to GPCR-Ligand Structures.

Published in:

Neurochemical Research, 2014, v. 39, n. 10, p. 1850, doi. 10.1007/s11064-014-1398-8

By:

Kooistra, Albert;
Graaf, Chris;
Timmerman, Henk

Publication type:

Article

Introduction to Special Issue in Honor of Professor Povl Krogsgaard-Larsen.

Published in:

Neurochemical Research, 2014, v. 39, n. 10, p. 1845, doi. 10.1007/s11064-014-1408-x

By:

Bräuner-Osborne, Hans;
Schousboe, Arne

Publication type:

Article

Group III Metabotropic Glutamate Receptors: Pharmacology, Physiology and Therapeutic Potential.

Published in:

Neurochemical Research, 2014, v. 39, n. 10, p. 1876, doi. 10.1007/s11064-014-1415-y

By:

Mercier, Marion;
Lodge, David

Publication type:

Article

Povl Krogsgaard-Larsen: A Giant in Medicinal Chemistry Research.

Published in:

Neurochemical Research, 2014, v. 39, n. 10, p. 1847, doi. 10.1007/s11064-014-1437-5

By:

Bøgesø, Klaus

Publication type:

Article

Muscimol as an Ionotropic GABA Receptor Agonist.

Published in:

Neurochemical Research, 2014, v. 39, n. 10, p. 1942, doi. 10.1007/s11064-014-1245-y

By:

Johnston, Graham

Publication type:

Article