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First-in-human multicenter phase I study of BMS-936561 (MDX-1203), an antibody-drug conjugate targeting CD70.
Published in:
2016
By:
- Owonikoko, Taofeek;
- Hussain, Arif;
- Stadler, Walter;
- Smith, David;
- Kluger, Harriet;
- Molina, Ana;
- Gulati, Parul;
- Shah, Aadhar;
- Ahlers, Christoph;
- Cardarelli, Pina;
- Cohen, Lewis;
- Owonikoko, Taofeek Kunle;
- Stadler, Walter Michael;
- Smith, David C;
- Molina, Ana M;
- Ahlers, Christoph Matthias;
- Cardarelli, Pina M;
- Cohen, Lewis J
Publication type:
journal article
Population pharmacokinetic and exposure-response analysis for trastuzumab administered using a subcutaneous "manual syringe" injection or intravenously in women with HER2-positive early breast cancer.
Published in:
2016
By:
- Quartino, Angelica;
- Hillenbach, Carina;
- Li, Jing;
- Li, Hanbin;
- Wada, Russell;
- Visich, Jennifer;
- Li, Chunze;
- Heinzmann, Dominik;
- Jin, Jin;
- Lum, Bert;
- Quartino, Angelica L;
- Wada, Russell D;
- Jin, Jin Y;
- Lum, Bert L
Publication type:
journal article
Elevated circulating monocyte chemoattractant protein 1 (MCP-1/CCL-2) level may be an unfavorable predictive factor to platinum- and taxane-based combination chemotherapy in patients with gastric cancer.
Published in:
2016
By:
- Tas, Faruk;
- Karabulut, Senem;
- Serilmez, Murat;
- Karabulut, Mehmet;
- Duranyildiz, Derya
Publication type:
journal article
High CYP2C19 phenotypic variability in gastrointestinal cancer patients.
Published in:
2016
By:
- Burns, K.;
- Lo, W.-Y.;
- Findlay, M.;
- Sharples, K.;
- Laking, G.;
- Helsby, N.;
- Burns, K E;
- Findlay, M P;
- Helsby, N A
Publication type:
journal article
A novelly synthesized phenanthroline derivative is a promising DNA-damaging anticancer agent inhibiting G1/S checkpoint transition and inducing cell apoptosis in cancer cells.
Published in:
2016
By:
- Zhen, Ni;
- Yang, Qingyuan;
- Wu, Qiong;
- Zhu, Xinyi;
- Wang, Yue;
- Sun, Fenyong;
- Mei, Wenjie;
- Yu, Yongchun
Publication type:
journal article
Population pharmacokinetic modeling of idelalisib, a novel PI3Kδ inhibitor, in healthy subjects and patients with hematologic malignancies.
Published in:
2016
By:
- Jin, Feng;
- Gao, Yuying;
- Zhou, Huafeng;
- Fang, Lorna;
- Li, Xiaoming;
- Ramanathan, Srini
Publication type:
journal article
A phase I study of two dosing schedules of oral BI 847325 in patients with advanced solid tumors.
Published in:
2016
By:
- Schöffski, Patrick;
- Aftimos, Philippe;
- Dumez, Herlinde;
- Deleporte, Amélie;
- Block, Katrien;
- Costermans, Jo;
- Billiet, Maureen;
- Meeus, Marie-Anne;
- Lee, Chooi;
- Schnell, David;
- Goeldner, Rainer-Georg;
- Awada, Ahmad;
- Schöffski, Patrick;
- Deleporte, Amélie;
- De Block, Katrien
Publication type:
journal article
Oxaliplatin in the era of personalized medicine: from mechanistic studies to clinical efficacy.
Published in:
2016
By:
- Perego, Paola;
- Robert, Jacques
Publication type:
journal article
A phase II trial of modified FOLFOX6 as first-line therapy for adenocarcinoma of an unknown primary site.
Published in:
2016
By:
- Shin, Dong-Yeop;
- Choi, Yoon;
- Lee, Hyo-Rak;
- Na, Im;
- Yuh, Young;
- Kim, Bong-Seog;
- Chung, Ik;
- Bae, Woo-Kyun;
- Shim, Hyun-Jeong;
- Song, Eun-Kee;
- Yang, Sung;
- Kang, Hye;
- Choi, Yoon Hee;
- Na, Im Il;
- Yuh, Young Jin;
- Chung, Ik Joo;
- Yang, Sung Hyun;
- Kang, Hye Jin
Publication type:
journal article
A multicenter prospective phase II trial of neoadjuvant epirubicin, cyclophosphamide, and 5-fluorouracil (FEC100) followed by cisplatin-docetaxel with or without trastuzumab in locally advanced breast cancer.
Published in:
2016
By:
- AL-Tweigeri, Taher;
- AlSayed, Adher;
- Alawadi, Shafika;
- Ibrahim, Mohamed;
- Ashour, Wafaa;
- Jaafar, Hassan;
- Abulkhair, Omalkhair;
- AL-Abdulkarim, Huda;
- Khalid, Hassan;
- Ajarim, Dahish;
- A L-Tweigeri, Taher;
- A L-Abdulkarim, Huda;
- Gulf Oncology Research Group (GORG-001)
Publication type:
journal article
Pharmacodynamic modeling of combined chemotherapeutic effects predicts synergistic activity of gemcitabine and trabectedin in pancreatic cancer cells.
Published in:
2016
By:
- Miao, Xin;
- Koch, Gilbert;
- Straubinger, Robert;
- Jusko, William;
- Straubinger, Robert M;
- Jusko, William J
Publication type:
journal article
The ability of mannitol to decrease cisplatin-induced nephrotoxicity in children: real or not?
Published in:
2016
By:
- Ruggiero, Antonio;
- Rizzo, Daniela;
- Trombatore, Giovanna;
- Maurizi, Palma;
- Riccardi, Riccardo
Publication type:
journal article
Malformin A1 promotes cell death through induction of apoptosis, necrosis and autophagy in prostate cancer cells.
Published in:
2016
By:
- Liu, Yongqing;
- Wang, Ming;
- Wang, Dawei;
- Li, Xiaobin;
- Wang, Wei;
- Lou, Hongxiang;
- Yuan, Huiqing
Publication type:
journal article
Impact of dexrazoxane on doxorubicin-induced aneuploidy in somatic and germinal cells of male mice.
Published in:
2016
By:
- Attia, S.;
- Ahmad, S.;
- Bakheet, S.;
- Attia, S M;
- Ahmad, S F;
- Bakheet, S A
Publication type:
journal article
Identification of polymorphic variants associated with erlotinib-related skin toxicity in advanced non-small cell lung cancer patients by DMET microarray analysis.
Published in:
2016
By:
- Arbitrio, Mariamena;
- Martino, Maria;
- Barbieri, Vito;
- Agapito, Giuseppe;
- Guzzi, Pietro;
- Botta, Cirino;
- Iuliano, Eleonora;
- Scionti, Francesca;
- Altomare, Emanuela;
- Codispoti, Stefania;
- Conforti, Serafino;
- Cannataro, Mario;
- Tassone, Pierfrancesco;
- Tagliaferri, Pierosandro;
- Di Martino, Maria Teresa;
- Guzzi, Pietro Hiram
Publication type:
journal article
Cytotoxic drugs: past, present and future.
Published in:
2016
By:
- Newell, Herbie;
- Sausville, Edward
Publication type:
journal article
Capecitabine with/without mitomycin C: results of a randomized phase II trial of second-line therapy in advanced biliary tract adenocarcinoma.
Published in:
2016
By:
- Cereda, S.;
- Milella, M.;
- Cordio, S.;
- Leone, F.;
- Aprile, G.;
- Galiano, A.;
- Mosconi, S.;
- Vasile, E.;
- Santini, D.;
- Belli, C.;
- Auriemma, A.;
- Novarino, A.;
- Vaccaro, V.;
- Martines, C.;
- Marino, D.;
- Lutrino, S.;
- Palazzo, V.;
- Reinach, B.;
- Aldrighetti, L.;
- Reni, M.
Publication type:
journal article
Hydroxyurea with or without imatinib in the treatment of recurrent or progressive meningiomas: a randomized phase II trial by Gruppo Italiano Cooperativo di Neuro-Oncologia (GICNO).
Published in:
2016
By:
- Mazza, Elena;
- Brandes, Alba;
- Zanon, Silvia;
- Eoli, Marika;
- Lombardi, Giuseppe;
- Faedi, Marina;
- Franceschi, Enrico;
- Reni, Michele
Publication type:
journal article
Phase I study assessing the feasibility of the triple combination chemotherapy of SOXIRI (S-1/oxaliplatin/irinotecan) in patients with unresectable pancreatic ductal adenocarcinoma.
Published in:
2016
By:
- Yanagimoto, Hiroaki;
- Satoi, Sohei;
- Sho, Masayuki;
- Akahori, Takahiro;
- Yamamoto, Tomohisa;
- Hirooka, Satoshi;
- Yamaki, So;
- Kotsuka, Masaya;
- Ryota, Hironori;
- Kinoshita, Shoichi;
- Nishiwada, Satoshi;
- Nagai, Minako;
- Ikeda, Naoya;
- Tsuta, Koji;
- Nakajima, Yoshiyuki;
- Kon, Masanori
Publication type:
journal article
Enhanced brain distribution of carboplatin in a primate model after blood-brain barrier disruption using an implantable ultrasound device.
Published in:
2016
By:
- Goldwirt, Lauriane;
- Canney, Michael;
- Horodyckid, Catherine;
- Poupon, Joel;
- Mourah, Samia;
- Vignot, Alexandre;
- Chapelon, Jean-Yves;
- Carpentier, Alexandre
Publication type:
journal article
Metabolism and disposition of the DOT1L inhibitor, pinometostat (EPZ-5676), in rat, dog and human.
Published in:
2016
By:
- Waters, Nigel;
- Smith, Sherri;
- Olhava, Edward;
- Duncan, Kenneth;
- Burton, Richard;
- O'Neill, James;
- Rodrigue, Marie-Eve;
- Pollock, Roy;
- Moyer, Mikel;
- Chesworth, Richard;
- Waters, Nigel J;
- Smith, Sherri A;
- Olhava, Edward J;
- Duncan, Kenneth W;
- Burton, Richard D;
- Pollock, Roy M;
- Moyer, Mikel P
Publication type:
journal article
Early metabolic change in (18)F-FDG-PET by measuring the single largest lesion predicts chemotherapeutic effects and patients' survival: PEACH study.
Published in:
2016
By:
- Tanaka, Yusuke;
- Ueda, Yutaka;
- Egawa-Takata, Tomomi;
- Matsuzaki, Shinya;
- Kobayashi, Eiji;
- Yoshino, Kiyoshi;
- Enomoto, Takayuki;
- Tatsumi, Mitsuaki;
- Kimura, Tadashi
Publication type:
journal article
Clinical practice guidelines for the diagnosis and treatment of patients with soft tissue sarcoma by the Spanish group for research in sarcomas (GEIS).
Published in:
2016
By:
- Garcia del Muro, Xavier;
- Alava, Enrique;
- Artigas, Vicenç;
- Bague, Silvia;
- Braña, Alejandro;
- Cubedo, Ricardo;
- Cruz, Josefina;
- Mulet-Margalef, Nuria;
- Narvaez, Jose;
- Martinez Tirado, Oscar;
- Valverde, Claudia;
- Verges, Ramona;
- Viñals, Joan;
- Martin-Broto, Javier;
- de Alava, Enrique;
- Artigas, Vicenç;
- Braña, Alejandro;
- Narvaez, Jose A;
- Viñals, Joan;
- Spanish Group for Research on Sarcoma
Publication type:
journal article
Acknowledgement of reviewers 2014.
Published in:
2016
Publication type:
journal article
Contemporary reviews on cancer treatment.
Published in:
2016
By:
- Peters, Godefridus;
- Raymond, Eric;
- Peters, Godefridus J
Publication type:
journal article

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