Works in Cancer Chemotherapy & Pharmacology, 2015, Vol 75, Issue 5

Results: 27

A phase I study of intraperitoneal nanoparticulate paclitaxel (Nanotax®) in patients with peritoneal malignancies.

Published in:

2015

By:

Williamson, Stephen K;
Johnson, Gary A;
Maulhardt, Holly A;
Moore, Kathleen M;
McMeekin, D S;
Schulz, Thomas K;
Reed, Gregory A;
Roby, Katherine F;
Mackay, Christine B;
Smith, Holly J;
Weir, Scott J;
Wick, Jo A;
Markman, Maurie;
diZerega, Gere S;
Baltezor, Michael J;
Espinosa, Jahna;
Decedue, Charles J

Publication type:

journal article

Positron emission tomography imaging of human colon cancer xenografts in mice with [18F]fluorothymidine after TAS-102 treatment.

Published in:

2015

By:

Lee, Haeng Jung;
Oh, Seung Jun;
Lee, Eun Jung;
Chung, Jin Hwa;
Kim, Yeseulmi;
Ryu, Jin-Sook;
Kim, Seog Young;
Lee, Seung Jin;
Moon, Dae Hyuk;
Kim, Tae Won

Publication type:

journal article

Unexpected hepatotoxicity in a phase I study of TAS266, a novel tetravalent agonistic Nanobody® targeting the DR5 receptor.

Published in:

2015

By:

Papadopoulos, Kyriakos P;
Isaacs, Randi;
Bilic, Sanela;
Kentsch, Kerstin;
Huet, Heather A;
Hofmann, Matthias;
Rasco, Drew;
Kundamal, Nicole;
Tang, Zhongwhen;
Cooksey, Jennifer;
Mahipal, Amit

Publication type:

journal article

Motesanib with or without panitumumab plus FOLFIRI or FOLFOX for the treatment of metastatic colorectal cancer.

Published in:

Cancer Chemotherapy & Pharmacology, 2015, v. 75, n. 5, p. 993, doi. 10.1007/s00280-015-2694-y

By:

Tebbutt, Niall;
Kotasek, Dusan;
Burris, Howard;
Schwartzberg, Lee;
Hurwitz, Herbert;
Stephenson, Joe;
Warner, Douglas;
Chen, Lisa;
Hsu, Cheng-Pang;
Goldstein, David

Publication type:

Article

First-in-human, phase I/IIa dose-escalation and safety study of balugrastim in breast cancer patients receiving myelosuppressive chemotherapy.

Published in:

Cancer Chemotherapy & Pharmacology, 2015, v. 75, n. 5, p. 929, doi. 10.1007/s00280-015-2703-1

By:

Avisar, Noa;
Adar, Liat;
Bock, Jason;
Müller, Udo;
Shen, David;
Barash, Steve;
Pukac, Laurie

Publication type:

Article

Phase I study of the safety and pharmacokinetics of trabectedin with docetaxel in patients with advanced malignancies.

Published in:

Cancer Chemotherapy & Pharmacology, 2015, v. 75, n. 5, p. 1047, doi. 10.1007/s00280-015-2705-z

By:

Mehren, Margaret;
Bookman, Michael;
Meropol, Neal;
Weiner, Louis;
Sherman, Eric;
Li, Jinhui;
Knoblauch, Roland;
Parekh, Trilok;
Cohen, Roger

Publication type:

Article

The effect of food on the pharmacokinetics of oral ibrutinib in healthy participants and patients with chronic lymphocytic leukemia.

Published in:

Cancer Chemotherapy & Pharmacology, 2015, v. 75, n. 5, p. 907, doi. 10.1007/s00280-015-2708-9

By:

Jong, Jan;
Sukbuntherng, Juthamas;
Skee, Donna;
Murphy, Joe;
O'Brien, Susan;
Byrd, John;
James, Danelle;
Hellemans, Peter;
Loury, David;
Jiao, Juhui;
Chauhan, Vijay;
Mannaert, Erik

Publication type:

Article

Activated STAT3 correlates with prognosis of non-small cell lung cancer and indicates new anticancer strategies.

Published in:

Cancer Chemotherapy & Pharmacology, 2015, v. 75, n. 5, p. 917, doi. 10.1007/s00280-015-2710-2

By:

Yu, Yang;
Zhao, Qian;
Wang, Zhou;
Liu, Xiang-Yan

Publication type:

Article

Plasma and cerebrospinal fluid pharmacokinetics of the Akt inhibitor, perifosine, in a non-human primate model.

Published in:

Cancer Chemotherapy & Pharmacology, 2015, v. 75, n. 5, p. 923, doi. 10.1007/s00280-015-2711-1

By:

Cole, Diane;
Lester-McCully, Cynthia;
Widemann, Brigitte;
Warren, Katherine

Publication type:

Article

Unexpected hepatotoxicity in a phase I study of TAS266, a novel tetravalent agonistic Nanobody targeting the DR5 receptor.

Published in:

Cancer Chemotherapy & Pharmacology, 2015, v. 75, n. 5, p. 887, doi. 10.1007/s00280-015-2712-0

By:

Papadopoulos, Kyriakos;
Isaacs, Randi;
Bilic, Sanela;
Kentsch, Kerstin;
Huet, Heather;
Hofmann, Matthias;
Rasco, Drew;
Kundamal, Nicole;
Tang, Zhongwhen;
Cooksey, Jennifer;
Mahipal, Amit

Publication type:

Article

Preclinical examination of clofarabine in pediatric ependymoma: intratumoral concentrations insufficient to warrant further study.

Published in:

Cancer Chemotherapy & Pharmacology, 2015, v. 75, n. 5, p. 897, doi. 10.1007/s00280-015-2713-z

By:

Patel, Yogesh;
Jacus, Megan;
Boulos, Nidal;
Dapper, Jason;
Davis, Abigail;
Vuppala, Pradeep;
Freeman, Burgess;
Mohankumar, Kumarasamypet;
Throm, Stacy;
Gilbertson, Richard;
Stewart, Clinton

Publication type:

Article

Sequential treatment with epirubicin, oxaliplatin and 5FU (EOF) followed by docetaxel, oxaliplatin and 5FU (DOF) in patients with advanced gastric or gastroesophageal cancer: a single-institution experience.

Published in:

Cancer Chemotherapy & Pharmacology, 2015, v. 75, n. 5, p. 941, doi. 10.1007/s00280-015-2715-x

By:

Petrioli, Roberto;
Francini, Edoardo;
Roviello, Franco;
Marrelli, Daniele;
Fiaschi, Anna;
Laera, Letizia;
Rossi, Giulia;
Bianco, V.;
Brozzetti, S.;
Roviello, Giandomenico

Publication type:

Article

Ginkgolide B protects against cisplatin-induced ototoxicity: enhancement of Akt-Nrf2-HO-1 signaling and reduction of NADPH oxidase.

Published in:

Cancer Chemotherapy & Pharmacology, 2015, v. 75, n. 5, p. 949, doi. 10.1007/s00280-015-2716-9

By:

Ma, Weijun;
Hu, Juan;
Cheng, Ying;
Wang, Junli;
Zhang, Xiaotong;
Xu, Min

Publication type:

Article

Mercaptopurine metabolite levels are predictors of bone marrow toxicity following high-dose methotrexate therapy of childhood acute lymphoblastic leukaemia.

Published in:

Cancer Chemotherapy & Pharmacology, 2015, v. 75, n. 5, p. 1089, doi. 10.1007/s00280-015-2717-8

By:

Vang, Sophia;
Schmiegelow, Kjeld;
Frandsen, Thomas;
Rosthøj, Susanne;
Nersting, Jacob

Publication type:

Article

Positron emission tomography imaging of human colon cancer xenografts in mice with [F]fluorothymidine after TAS-102 treatment.

Published in:

Cancer Chemotherapy & Pharmacology, 2015, v. 75, n. 5, p. 1005, doi. 10.1007/s00280-015-2718-7

By:

Lee, Haeng;
Oh, Seung;
Lee, Eun;
Chung, Jin;
Kim, Yeseulmi;
Ryu, Jin-Sook;
Kim, Seog;
Lee, Seung;
Moon, Dae;
Kim, Tae

Publication type:

Article

Effects of cyclosporine A on the hepatobiliary disposition and hepatic uptake of etoposide in an isolated perfused rat liver model.

Published in:

Cancer Chemotherapy & Pharmacology, 2015, v. 75, n. 5, p. 961, doi. 10.1007/s00280-015-2719-6

By:

Khezrian, Mina;
Sheikholeslami, Behjat;
Dadashzadeh, Simin;
Lavasani, Hoda;
Rouini, Mohammadreza

Publication type:

Article

Dose selection of siltuximab for multicentric Castleman's disease.

Published in:

Cancer Chemotherapy & Pharmacology, 2015, v. 75, n. 5, p. 1037, doi. 10.1007/s00280-015-2720-0

By:

Mayer, Christina;
Xie, Lanyi;
Bandekar, Rajesh;
Qi, Ming;
Velde, Helgi;
Reddy, Manjula;
Qin, Xiang;
Davis, Hugh;
Puchalski, Thomas

Publication type:

Article

Levels of sirolimus in saliva and blood following oral topical sustained-release varnish delivery system application.

Published in:

Cancer Chemotherapy & Pharmacology, 2015, v. 75, n. 5, p. 969, doi. 10.1007/s00280-015-2721-z

By:

Nudelman, Zakhar;
Findler, Mordechai;
Barasch, Dinorah;
Nemirovski, Alina;
Pikovsky, Anna;
Kirmayer, David;
Basheer, Maamoun;
Gutkind, J.;
Friedman, Michael;
Czerninski, Rakefet

Publication type:

Article

Plasma pharmacokinetics of the indenoisoquinoline topoisomerase I inhibitor, NSC 743400, in rats and dogs.

Published in:

Cancer Chemotherapy & Pharmacology, 2015, v. 75, n. 5, p. 1015, doi. 10.1007/s00280-015-2722-y

By:

Muzzio, Miguel;
Hu, Shu-Chieh;
Holleran, Julianne;
Parise, Robert;
Eiseman, Julie;
Yellow-Duke, Archibong;
Covey, Joseph;
Glaze, Elizabeth;
Engelke, Kory;
Egorin, Merrill;
McCormick, David;
Beumer, Jan

Publication type:

Article

Organic cation transporter OCT6 mediates cisplatin uptake and resistance to cisplatin in lung cancer.

Published in:

Cancer Chemotherapy & Pharmacology, 2015, v. 75, n. 5, p. 985, doi. 10.1007/s00280-015-2723-x

By:

Kunii, Eiji;
Oguri, Tetsuya;
Kasai, Daishi;
Ozasa, Hiroaki;
Uemura, Takehiro;
Takakuwa, Osamu;
Ohkubo, Hirotsugu;
Takemura, Masaya;
Maeno, Ken;
Niimi, Akio

Publication type:

Article

Pharmacokinetically based dosing of weekly paclitaxel to reduce drug-related neurotoxicity based on a single sample strategy.

Published in:

Cancer Chemotherapy & Pharmacology, 2015, v. 75, n. 5, p. 975, doi. 10.1007/s00280-015-2724-9

By:

Kraff, Stefanie;
Nieuweboer, Annemieke;
Mathijssen, Ron;
Baty, Florent;
Graan, Anne-Joy;
Schaik, Ron;
Jaehde, Ulrich;
Joerger, Markus

Publication type:

Article

Vascular endothelial growth factor receptor tyrosine kinase inhibitor (VEGFR-TKI) rechallenge for patients with metastatic renal cell carcinoma after treatment failure using both VEGFR-TKI and mTOR inhibitor.

Published in:

Cancer Chemotherapy & Pharmacology, 2015, v. 75, n. 5, p. 1025, doi. 10.1007/s00280-015-2725-8

By:

Park, Inkeun;
Lee, Jae-Lyun;
Ahn, Jin-Hee;
Lee, Dae-Ho;
Lee, Kyoo-Hyung;
You, Dalsan;
Jeong, In;
Song, Cheryn;
Hong, Bumsik;
Hong, Jun;
Ahn, Hanjong

Publication type:

Article

A phase I trial of intravenous catumaxomab: a bispecific monoclonal antibody targeting EpCAM and the T cell coreceptor CD3.

Published in:

Cancer Chemotherapy & Pharmacology, 2015, v. 75, n. 5, p. 1065, doi. 10.1007/s00280-015-2728-5

By:

Mau-Sørensen, Morten;
Dittrich, Christian;
Dienstmann, Rodrigo;
Lassen, Ulrik;
Büchler, Wilfried;
Martinius, Holger;
Tabernero, Josep

Publication type:

Article

Validation of a fast and low-cost alkaline lysis method for gDNA extraction in a pharmacogenetic context.

Published in:

Cancer Chemotherapy & Pharmacology, 2015, v. 75, n. 5, p. 1095, doi. 10.1007/s00280-015-2729-4

By:

Ramos-Díaz, Ruth;
Gutiérrez-Nicolás, Fernando;
Nazco-Casariego, Gloria J;
González-Perera, Itamar;
Pérez-Pérez, José A

Publication type:

Article

Protective effects of C-type natriuretic peptide on cisplatin-induced nephrotoxicity in Mice.

Published in:

Cancer Chemotherapy & Pharmacology, 2015, v. 75, n. 5, p. 1057, doi. 10.1007/s00280-015-2734-7

By:

Kimura, Toru;
Nojiri, Takashi;
Hosoda, Hiroshi;
Ishikane, Shin;
Shintani, Yasushi;
Inoue, Masayoshi;
Miyazato, Mikiya;
Okumura, Meinoshin;
Kangawa, Kenji

Publication type:

Article

A phase I study of intraperitoneal nanoparticulate paclitaxel (Nanotax) in patients with peritoneal malignancies.

Published in:

2015

By:

Williamson, Stephen;
Johnson, Gary;
Maulhardt, Holly;
Moore, Kathleen;
McMeekin, D.;
Schulz, Thomas;
Reed, Gregory;
Roby, Katherine;
Mackay, Christine;
Smith, Holly;
Weir, Scott;
Wick, Jo;
Markman, Maurie;
diZerega, Gere;
Baltezor, Michael;
Espinosa, Jahna;
Decedue, Charles

Publication type:

Report

Autophagy in cancer stem/progenitor cells.

Published in:

Cancer Chemotherapy & Pharmacology, 2015, v. 75, n. 5, p. 879, doi. 10.1007/s00280-014-2634-2

By:

Lin, Yi-Hui;
Huang, Yu-Chun;
Chen, Li-Hsin;
Chu, Pei-Ming

Publication type:

Article