Works in Cancer Chemotherapy & Pharmacology, 2015, Vol 75, Issue 3

Results: 27

A phase I, pharmacokinetic, and pharmacodynamic evaluation of the DNA methyltransferase inhibitor 5-fluoro-2'-deoxycytidine, administered with tetrahydrouridine.
Published in:
2015
By:
- Newman, Edward M;
- Morgan, Robert J;
- Kummar, Shivaani;
- Beumer, Jan H;
- Blanchard, M Suzette;
- Ruel, Christopher;
- El-Khoueiry, Anthony B;
- Carroll, Mary I;
- Hou, Jessie M;
- Li, Chun;
- Lenz, Heinz J;
- Eiseman, Julie L;
- Doroshow, James H
Publication type:
journal article
Phase I/II study of gefitinib (Iressa(®)) and vorinostat (IVORI) in previously treated patients with advanced non-small cell lung cancer.
Published in:
2015
By:
- Han, Ji-Youn;
- Lee, Soo Hyun;
- Lee, Geon Kook;
- Yun, Tak;
- Lee, Young Joo;
- Hwang, Kum Hui;
- Kim, Jin Young;
- Kim, Heung Tae
Publication type:
journal article
Pan-PI-3 kinase inhibitor SF1126 shows antitumor and antiangiogenic activity in renal cell carcinoma.
Published in:
Cancer Chemotherapy & Pharmacology, 2015, v. 75, n. 3, p. 595, doi. 10.1007/s00280-014-2639-x
By:
- Joshi, Shweta;
- Singh, Alok;
- Durden, Donald
Publication type:
Article
Endostar in combination with modified FOLFOX6 as an initial therapy in advanced colorectal cancer patients: a phase I clinical trial.
Published in:
Cancer Chemotherapy & Pharmacology, 2015, v. 75, n. 3, p. 547, doi. 10.1007/s00280-014-2656-9
By:
- Chen, Zhiyu;
- Guo, Weijian;
- Cao, Junning;
- Lv, Fangfang;
- Zhang, Wen;
- Qiu, Lixin;
- Li, Wenhua;
- Ji, Dongmei;
- Zhang, Sheng;
- Xia, Zuguang;
- Wang, Jiachen;
- Li, Jin
Publication type:
Article
Pharmacokinetics of neamine in rats and anti-cervical cancer activity in vitro and in vivo.
Published in:
Cancer Chemotherapy & Pharmacology, 2015, v. 75, n. 3, p. 465, doi. 10.1007/s00280-014-2658-7
By:
- Liu, Yaping;
- Zhang, Xiaoyan;
- An, Songlin;
- Wu, Yanli;
- Hu, Guofu;
- Wu, Yunxia
Publication type:
Article
Phase I/II study of docetaxel, cisplatin, and 5-fluorouracil combination chemoradiotherapy in patients with advanced esophageal cancer.
Published in:
Cancer Chemotherapy & Pharmacology, 2015, v. 75, n. 3, p. 449, doi. 10.1007/s00280-014-2659-6
By:
- Miyazaki, Tatsuya;
- Sohda, Makoto;
- Tanaka, Naritaka;
- Suzuki, Shigemasa;
- Ieta, Keisuke;
- Sakai, Makoto;
- Sano, Akihiko;
- Yokobori, Takehiko;
- Inose, Takanori;
- Nakajima, Masanobu;
- Fukuchi, Minoru;
- Ojima, Hitoshi;
- Kato, Hiroyuki;
- Kuwano, Hiroyuki
Publication type:
Article
Population pharmacokinetic analysis of oxaliplatin in adults and children identifies important covariates for dosing.
Published in:
Cancer Chemotherapy & Pharmacology, 2015, v. 75, n. 3, p. 495, doi. 10.1007/s00280-014-2667-6
By:
- Nikanjam, Mina;
- Stewart, Clinton;
- Takimoto, Chris;
- Synold, Timothy;
- Beaty, Orren;
- Fouladi, Maryam;
- Capparelli, Edmund
Publication type:
Article
The newly synthesized anticancer drug HUHS1015 is useful for treatment of human gastric cancer.
Published in:
Cancer Chemotherapy & Pharmacology, 2015, v. 75, n. 3, p. 527, doi. 10.1007/s00280-014-2661-z
By:
- Kaku, Yoshiko;
- Tsuchiya, Ayako;
- Kanno, Takeshi;
- Nakao, Shuhei;
- Shimizu, Tadashi;
- Tanaka, Akito;
- Nishizaki, Tomoyuki
Publication type:
Article
Regulatory role of Lactobacillus acidophilus on inflammation and gastric dysmotility in intestinal mucositis induced by 5-fluorouracil in mice.
Published in:
Cancer Chemotherapy & Pharmacology, 2015, v. 75, n. 3, p. 559, doi. 10.1007/s00280-014-2663-x
By:
- Justino, Priscilla;
- Melo, Luis;
- Nogueira, Andre;
- Morais, Cecila;
- Mendes, Walber;
- Franco, Alvaro;
- Souza, Emmanuel;
- Ribeiro, Ronaldo;
- Souza, Marcellus;
- Soares, Pedro
Publication type:
Article
Phase I/II study of gefitinib (Iressa) and vorinostat (IVORI) in previously treated patients with advanced non-small cell lung cancer.
Published in:
Cancer Chemotherapy & Pharmacology, 2015, v. 75, n. 3, p. 475, doi. 10.1007/s00280-014-2664-9
By:
- Han, Ji-Youn;
- Lee, Soo;
- Lee, Geon;
- Yun, Tak;
- Lee, Young;
- Hwang, Kum;
- Kim, Jin;
- Kim, Heung
Publication type:
Article
Retrospective analysis of fixed dose rate infusion of gemcitabine and S-1 combination therapy (FGS) as salvage chemotherapy in patients with gemcitabine-refractory advanced pancreatic cancer: inflammation-based prognostic score predicts survival.
Published in:
Cancer Chemotherapy & Pharmacology, 2015, v. 75, n. 3, p. 457, doi. 10.1007/s00280-014-2665-8
By:
- Kasuga, Akiyoshi;
- Okano, Naohiro;
- Naruge, Daisuke;
- Kitamura, Hiroshi;
- Takasu, Atsuko;
- Nagashima, Fumio;
- Furuse, Junji
Publication type:
Article
Dosing algorithm revisit for busulfan following IV infusion.
Published in:
Cancer Chemotherapy & Pharmacology, 2015, v. 75, n. 3, p. 505, doi. 10.1007/s00280-014-2660-0
By:
- Wang, Yanlin;
- Kato, Kazunobu;
- Gallo, Christopher;
- Armstrong, Elizabeth;
- Rock, Edwin;
- Wang, Xiaofeng
Publication type:
Article
Safety and activity of temsirolimus and bevacizumab in patients with advanced renal cell carcinoma previously treated with tyrosine kinase inhibitors: a phase 2 consortium study.
Published in:
Cancer Chemotherapy & Pharmacology, 2015, v. 75, n. 3, p. 485, doi. 10.1007/s00280-014-2668-5
By:
- Merchan, Jaime;
- Qin, Rui;
- Pitot, Henry;
- Picus, Joel;
- Liu, Glenn;
- Fitch, Tom;
- Maples, William;
- Flynn, Patrick;
- Fruth, Briant;
- Erlichman, Charles
Publication type:
Article
Effect of platinum-based chemotherapy for non-small cell lung cancer patients with interstitial lung disease.
Published in:
Cancer Chemotherapy & Pharmacology, 2015, v. 75, n. 3, p. 521, doi. 10.1007/s00280-014-2670-y
By:
- Kenmotsu, Hirotsugu;
- Naito, Tateaki;
- Mori, Keita;
- Ko, Ryo;
- Ono, Akira;
- Wakuda, Kazushige;
- Imai, Hisao;
- Taira, Tetsuhiko;
- Murakami, Haruyasu;
- Endo, Masahiro;
- Takahashi, Toshiaki
Publication type:
Article
Phase I study of nanoliposomal irinotecan (PEP02) in advanced solid tumor patients.
Published in:
Cancer Chemotherapy & Pharmacology, 2015, v. 75, n. 3, p. 579, doi. 10.1007/s00280-014-2671-x
By:
- Chang, T.;
- Shiah, H.;
- Yang, C.;
- Yeh, K.;
- Cheng, A.;
- Shen, B.;
- Wang, Y.;
- Yeh, C.;
- Chiang, N.;
- Chang, J.;
- Chen, L.
Publication type:
Article
A dose-escalation study of oxaliplatin/capecitabine/irinotecan (XELOXIRI) and bevacizumab as a first-line therapy for patients with metastatic colorectal cancer.
Published in:
Cancer Chemotherapy & Pharmacology, 2015, v. 75, n. 3, p. 587, doi. 10.1007/s00280-014-2672-9
By:
- Sato, Yasushi;
- Ohnuma, Hiroyuki;
- Hirakawa, Masahiro;
- Takahashi, Minoru;
- Osuga, Takahiro;
- Okagawa, Yutaka;
- Murase, Kazuyuki;
- Takada, Kohichi;
- Kawano, Yutaka;
- Iyama, Satoshi;
- Hayashi, Tsuyoshi;
- Sato, Tsutomu;
- Miyanishi, Koji;
- Takimoto, Rishu;
- Kobune, Masayoshi;
- Okita, Kenji;
- Mizuguchi, Toru;
- Furuhata, Tomohisa;
- Hirata, Koichi;
- Kato, Junji
Publication type:
Article
A phase II study of biweekly paclitaxel and carboplatin in elderly patients with advanced non-small cell lung cancer.
Published in:
Cancer Chemotherapy & Pharmacology, 2015, v. 75, n. 3, p. 513, doi. 10.1007/s00280-014-2673-8
By:
- Soejima, Kenzo;
- Naoki, Katsuhiko;
- Ishioka, Kota;
- Nakamura, Morio;
- Nakatani, Michie;
- Kawada, Ichiro;
- Watanabe, Hideo;
- Nakachi, Ichiro;
- Yasuda, Hiroyuki;
- Satomi, Ryosuke;
- Nakayama, Sohei;
- Yoda, Satoshi;
- Ikemura, Sinnosuke;
- Terai, Hideki;
- Sato, Takashi;
- Ohgino, Keiko;
- Arai, Daisuke;
- Tani, Tetsuo;
- Kuroda, Aoi;
- Nishino, Makoto
Publication type:
Article
A phase I, pharmacokinetic, and pharmacodynamic evaluation of the DNA methyltransferase inhibitor 5-fluoro-2′-deoxycytidine, administered with tetrahydrouridine.
Published in:
Cancer Chemotherapy & Pharmacology, 2015, v. 75, n. 3, p. 537, doi. 10.1007/s00280-014-2674-7
By:
- Newman, Edward;
- Morgan, Robert;
- Kummar, Shivaani;
- Beumer, Jan;
- Blanchard, M.;
- Ruel, Christopher;
- El-Khoueiry, Anthony;
- Carroll, Mary;
- Hou, Jessie;
- Li, Chun;
- Lenz, Heinz;
- Eiseman, Julie;
- Doroshow, James
Publication type:
Article
A randomized phase II study of combination therapy with S-1, oral leucovorin, and oxaliplatin (SOL) and mFOLFOX6 in patients with previously untreated metastatic colorectal cancer.
Published in:
Cancer Chemotherapy & Pharmacology, 2015, v. 75, n. 3, p. 569, doi. 10.1007/s00280-015-2676-0
By:
- Yamazaki, Kentaro;
- Kuwano, Hiroyuki;
- Ojima, Hitoshi;
- Otsuji, Toshio;
- Kato, Takeshi;
- Shimada, Ken;
- Hyodo, Ichinosuke;
- Nishina, Tomohiro;
- Shirao, Kuniaki;
- Esaki, Taito;
- Ohishi, Takashi;
- Denda, Tadamichi;
- Takeuchi, Masahiro;
- Boku, Narikazu
Publication type:
Article
Effect of axitinib on the QT interval in healthy volunteers.
Published in:
Cancer Chemotherapy & Pharmacology, 2015, v. 75, n. 3, p. 619, doi. 10.1007/s00280-015-2677-z
By:
- Ruiz-Garcia, Ana;
- Houk, Brett;
- Pithavala, Yazdi;
- Toh, Melvin;
- Sarapa, Nenad;
- Tortorici, Michael
Publication type:
Article
Erratum to: Does saturable formation of gemcitabine triphosphate occur in patients?
Published in:
2015
By:
- Tham, Lai-San;
- Wang, Ling-Zhi;
- Soo, Ross;
- Lee, How-Sung;
- Lee, Soo-Chin;
- Goh, Boon-Cher;
- Holford, Nicholas
Publication type:
Erratum
Myelotoxicity of carboplatin is increased in vivo in db/db mice, the animal model of obesity-associated diabetes mellitus.
Published in:
Cancer Chemotherapy & Pharmacology, 2015, v. 75, n. 3, p. 609, doi. 10.1007/s00280-015-2679-x
By:
- Géresi, Krisztina;
- Megyeri, Attila;
- Szabó, Boglárka;
- Szabó, Zsolt;
- Aradi, János;
- Németh, József;
- Benkő, Ilona
Publication type:
Article
Low-dose-intensity bevacizumab with weekly irinotecan for platinum- and taxanes-resistant epithelial ovarian cancer.
Published in:
2015
By:
- Liu, Ying;
- Ren, Zhonghai;
- Xu, Shuning;
- Bai, Hua;
- Ma, Ning;
- Wang, Feng
Publication type:
Report
A phase II study of capecitabine and oral leucovorin as a third-line chemotherapy in patients with metastatic colorectal cancer.
Published in:
Cancer Chemotherapy & Pharmacology, 2015, v. 75, n. 3, p. 639, doi. 10.1007/s00280-015-2688-9
By:
- Choi, Dae;
- Yoon, Sang;
- Kim, Hyeong;
- Kim, Jung;
- Kim, Kwang;
- Kim, Byung;
- Choi, Young;
- Kim, Jin;
- Han, Boram;
- Song, Hun;
- Zang, Dae
Publication type:
Article
Alliance A091103 a phase II study of the angiopoietin 1 and 2 peptibody trebananib for the treatment of angiosarcoma.
Published in:
Cancer Chemotherapy & Pharmacology, 2015, v. 75, n. 3, p. 629, doi. 10.1007/s00280-015-2689-8
By:
- D' Angelo, Sandra;
- Mahoney, Michelle;
- Tine, Brian;
- Adkins, Douglas;
- Perdekamp, Maria;
- Condy, Mercedes;
- Luke, Jason;
- Hartley, Eliza;
- Antonescu, Cristina;
- Tap, William;
- Schwartz, Gary
Publication type:
Article
Intermittent dosing of aromatase inhibitors (AI) to improve tolerance in postmenopausal women: a rationale for future clinical studies.
Published in:
Cancer Chemotherapy & Pharmacology, 2015, v. 75, n. 3, p. 653, doi. 10.1007/s00280-015-2690-2
By:
- Salmon, R.;
- Rey, J.;
- Launay-Vacher, V.
Publication type:
Article
Autophagy modulation: a target for cancer treatment development.
Published in:
Cancer Chemotherapy & Pharmacology, 2015, v. 75, n. 3, p. 439, doi. 10.1007/s00280-014-2637-z
By:
- Duffy, Alison;
- Le, Jackson;
- Sausville, Edward;
- Emadi, Ashkan
Publication type:
Article