Works in Cancer Chemotherapy & Pharmacology, 2014, Vol 74, Issue 5

Results: 27

A first-in-human study of the anti-α5β1 integrin monoclonal antibody PF-04605412 administered intravenously to patients with advanced solid tumors.
Published in:
2014
By:
- Mateo, J;
- Berlin, J;
- de Bono, J S;
- Cohen, R B;
- Keedy, V;
- Mugundu, G;
- Zhang, Lianglin;
- Abbattista, A;
- Davis, C;
- Gallo Stampino, C;
- Borghaei, H
Publication type:
journal article
Pharmacokinetics of the chimeric anti-GD2 antibody, ch14.18, in children with high-risk neuroblastoma.
Published in:
2014
By:
- Desai, Ami V;
- Fox, Elizabeth;
- Smith, L Mary;
- Lim, Allison Pecha;
- Maris, John M;
- Balis, Frank M
Publication type:
journal article
GEIS 2013 guidelines for gastrointestinal sarcomas (GIST).
Published in:
2014
By:
- Poveda, Andrés;
- Del Muro, Xavier García;
- López-Guerrero, Jose Antonio;
- Martínez, Virginia;
- Romero, Ignacio;
- Valverde, Claudia;
- Cubedo, Ricardo;
- Martín-Broto, Javier
Publication type:
journal article
A phase I dose-escalation study of MEDI-575, a PDGFRα monoclonal antibody, in adults with advanced solid tumors.
Published in:
2014
By:
- Becerra, Carlos R;
- Conkling, Paul;
- Vogelzang, Nicholas;
- Wu, Hilary;
- Hong, Shengyan;
- Narwal, Rajesh;
- Liang, Meina;
- Tavakkoli, Fatemeh;
- Pandya, Naimish
Publication type:
journal article
Mechanistic pharmacokinetic/pharmacodynamic modeling of in vivo tumor uptake, catabolism, and tumor response of trastuzumab maytansinoid conjugates.
Published in:
Cancer Chemotherapy & Pharmacology, 2014, v. 74, n. 5, p. 969, doi. 10.1007/s00280-014-2561-2
By:
- Wada, Russ;
- Erickson, Hans;
- Lewis Phillips, Gail;
- Provenzano, Carmela;
- Leipold, Douglas;
- Mai, Elaine;
- Johnson, Holly;
- Tibbitts, Jay
Publication type:
Article
A phase I trial of gemcitabine, S-1 and LV combination (GSL) therapy in advanced pancreatic cancer.
Published in:
Cancer Chemotherapy & Pharmacology, 2014, v. 74, n. 5, p. 911, doi. 10.1007/s00280-014-2563-0
By:
- Nakai, Yousuke;
- Isayama, Hiroyuki;
- Saito, Kei;
- Sasaki, Takashi;
- Takahara, Naminatsu;
- Hamada, Tsuyoshi;
- Mizuno, Suguru;
- Miyabayashi, Koji;
- Yamamoto, Keisuke;
- Mohri, Dai;
- Kogure, Hirofumi;
- Yamamoto, Natsuyo;
- Hirano, Kenji;
- Ijichi, Hideaki;
- Tateishi, Keisuke;
- Tada, Minoru;
- Koike, Kazuhiko
Publication type:
Article
Importance of branched-chain amino acids in patients with liver cirrhosis and advanced hepatocellular carcinoma receiving hepatic arterial infusion chemotherapy.
Published in:
Cancer Chemotherapy & Pharmacology, 2014, v. 74, n. 5, p. 899, doi. 10.1007/s00280-014-2564-z
By:
- Kanekawa, Takenori;
- Nagai, Hidenari;
- Kanayama, Masahiro;
- Sumino, Yasukiyo
Publication type:
Article
A phase I dose-escalation study of MEDI-575, a PDGFRα monoclonal antibody, in adults with advanced solid tumors.
Published in:
Cancer Chemotherapy & Pharmacology, 2014, v. 74, n. 5, p. 917, doi. 10.1007/s00280-014-2567-9
By:
- Becerra, Carlos;
- Conkling, Paul;
- Vogelzang, Nicholas;
- Wu, Hilary;
- Hong, Shengyan;
- Narwal, Rajesh;
- Liang, Meina;
- Tavakkoli, Fatemeh;
- Pandya, Naimish
Publication type:
Article
TACE plus sorafenib for the treatment of hepatocellular carcinoma: results of the multicenter, phase II SOCRATES trial.
Published in:
Cancer Chemotherapy & Pharmacology, 2014, v. 74, n. 5, p. 947, doi. 10.1007/s00280-014-2568-8
By:
- Erhardt, Andreas;
- Kolligs, Frank;
- Dollinger, Matthias;
- Schott, Eckart;
- Wege, Hennig;
- Bitzer, Michael;
- Gog, Christiane;
- Lammert, Frank;
- Schuchmann, Markus;
- Walter, Clemens;
- Blondin, Dirk;
- Ohmann, Christian;
- Häussinger, Dieter
Publication type:
Article
A phase I and pharmacokinetic study of oral perifosine with different loading schedules in patients with refractory neoplasms.
Published in:
Cancer Chemotherapy & Pharmacology, 2014, v. 74, n. 5, p. 955, doi. 10.1007/s00280-014-2569-7
By:
- Figg, William;
- Monga, Manish;
- Headlee, Donna;
- Shah, Avni;
- Chau, Cindy;
- Peer, Cody;
- Messman, Richard;
- Elsayed, Yusri;
- Murgo, Anthony;
- Melillo, Giovanni;
- Ryan, Qin;
- Kalnitskiy, Mikhail;
- Senderowicz, Adrian;
- Hollingshead, Melinda;
- Arbuck, Susan;
- Sausville, Edward
Publication type:
Article
Evaluation of gefitinib efficacy according to body surface area in patients with non-small cell lung cancer harboring an EGFR mutation.
Published in:
Cancer Chemotherapy & Pharmacology, 2014, v. 74, n. 5, p. 939, doi. 10.1007/s00280-014-2570-1
By:
- Igawa, Satoshi;
- Kasajima, Masashi;
- Ishihara, Mikiko;
- Kimura, Michiko;
- Hiyoshi, Yasuhiro;
- Niwa, Hideyuki;
- Kusuhara, Seiichiro;
- Harada, Shinya;
- Asakuma, Maiko;
- Otani, Sakiko;
- Katono, Ken;
- Sasaki, Jiichiro;
- Masuda, Noriyuki
Publication type:
Article
Effect of age on the pharmacokinetics of busulfan in patients undergoing hematopoietic cell transplantation; an alliance study (CALGB 10503, 19808, and 100103).
Published in:
Cancer Chemotherapy & Pharmacology, 2014, v. 74, n. 5, p. 927, doi. 10.1007/s00280-014-2571-0
By:
- Beumer, Jan;
- Owzar, Kouros;
- Lewis, Lionel;
- Jiang, Chen;
- Holleran, Julianne;
- Christner, Susan;
- Blum, William;
- Devine, Steven;
- Kolitz, Jonathan;
- Linker, Charles;
- Vij, Ravi;
- Alyea, Edwin;
- Larson, Richard;
- Ratain, Mark;
- Egorin, Merrill
Publication type:
Article
Non-surgical treatment versus radical esophagectomy for clinical T1N0M0 esophageal carcinoma: a single-center experience.
Published in:
Cancer Chemotherapy & Pharmacology, 2014, v. 74, n. 5, p. 995, doi. 10.1007/s00280-014-2573-y
By:
- Park, Inkeun;
- Kim, Yong-Hee;
- Yoon, Dok;
- Park, Sook;
- Kim, Hyeong;
- Kim, Jong;
- Jung, Hwoon-Yong;
- Lee, Gin;
- Cho, Kyung-Ja;
- Kim, Sung-Bae
Publication type:
Article
Expression of a novel peptide derived from PCNA damages DNA and reverses cisplatin resistance.
Published in:
Cancer Chemotherapy & Pharmacology, 2014, v. 74, n. 5, p. 981, doi. 10.1007/s00280-014-2574-x
By:
- Lingeman, Robert;
- Hickey, Robert;
- Malkas, Linda
Publication type:
Article
Pharmacokinetics of the chimeric anti-G antibody, ch14.18, in children with high-risk neuroblastoma.
Published in:
Cancer Chemotherapy & Pharmacology, 2014, v. 74, n. 5, p. 1047, doi. 10.1007/s00280-014-2575-9
By:
- Desai, Ami;
- Fox, Elizabeth;
- Smith, L.;
- Lim, Allison;
- Maris, John;
- Balis, Frank
Publication type:
Article
A first-in-human study of the anti-α5β1 integrin monoclonal antibody PF-04605412 administered intravenously to patients with advanced solid tumors.
Published in:
Cancer Chemotherapy & Pharmacology, 2014, v. 74, n. 5, p. 1039, doi. 10.1007/s00280-014-2576-8
By:
- Mateo, J.;
- Berlin, J.;
- Bono, J.;
- Cohen, R.;
- Keedy, V.;
- Mugundu, G.;
- Zhang, Lianglin;
- Abbattista, A.;
- Davis, C.;
- Gallo Stampino, C.;
- Borghaei, H.
Publication type:
Article
Antitumor activity of the selective ALK inhibitor alectinib in models of intracranial metastases.
Published in:
Cancer Chemotherapy & Pharmacology, 2014, v. 74, n. 5, p. 1023, doi. 10.1007/s00280-014-2578-6
By:
- Kodama, Tatsushi;
- Hasegawa, Masami;
- Takanashi, Kenji;
- Sakurai, Yuji;
- Kondoh, Osamu;
- Sakamoto, Hiroshi
Publication type:
Article
Phase I trial of hepatic arterial infusion (HAI) of floxuridine with modified oxaliplatin, 5-fluorouracil and leucovorin (m-FOLFOX6) in Chinese patients with unresectable liver metastases from colorectal cancer.
Published in:
2014
By:
- Li, Cong;
- Gu, Yangkui;
- Zhao, Ming;
- Yuan, Yunfei;
- Wang, Fenghua;
- Wang, Zhiqiang;
- Li, Wang;
- Luo, Huiyan;
- Chen, Cui;
- Chen, Gong;
- Ding, Peirong;
- Wu, Xiaojun;
- Lu, Zhenhai;
- Pan, Zhizhong;
- Xu, Ruihua;
- He, Youjian;
- Wan, Desen;
- Li, Yuhong
Publication type:
Report
Leucovorin rescue allows effective high-dose pralatrexate treatment and an increase in therapeutic index in mesothelioma xenografts.
Published in:
Cancer Chemotherapy & Pharmacology, 2014, v. 74, n. 5, p. 1029, doi. 10.1007/s00280-014-2580-z
By:
- Tedeschi, Philip;
- Kathari, Yamini;
- Farooqi, Iqra;
- Bertino, Joseph
Publication type:
Article
Prognostic value of human papillomavirus in anal squamous cell carcinoma.
Published in:
Cancer Chemotherapy & Pharmacology, 2014, v. 74, n. 5, p. 1033, doi. 10.1007/s00280-014-2582-x
By:
- Ravenda, Paola;
- Magni, Elena;
- Botteri, Edoardo;
- Manzotti, Michela;
- Barberis, Massimo;
- Vacirca, Davide;
- Trovato, Cristina;
- Dell'Acqua, Veronica;
- Leonardi, Maria;
- Sideri, Mario;
- Fazio, Nicola;
- Zampino, Maria
Publication type:
Article
Clinical study of the novel cyclin-dependent kinase inhibitor dinaciclib in combination with rituximab in relapsed/refractory chronic lymphocytic leukemia patients.
Published in:
Cancer Chemotherapy & Pharmacology, 2014, v. 74, n. 5, p. 1057, doi. 10.1007/s00280-014-2583-9
By:
- Fabre, Claire;
- Gobbi, Marco;
- Ezzili, Cyrine;
- Zoubir, Mustapha;
- Sablin, Marie-Paule;
- Small, Karen;
- Im, Ellie;
- Shinwari, Nabeegha;
- Zhang, Da;
- Zhou, Honghong;
- Tourneau, Christophe
Publication type:
Article
Heat shock protein 90 (HSP90) is overexpressed in p16-negative oropharyngeal squamous cell carcinoma, and its inhibition in vitro potentiates the effects of chemoradiation.
Published in:
Cancer Chemotherapy & Pharmacology, 2014, v. 74, n. 5, p. 1015, doi. 10.1007/s00280-014-2584-8
By:
- Patel, Kirtesh;
- Wen, Jing;
- Magliocca, Kelly;
- Muller, Susan;
- Liu, Yuan;
- Chen, Zhuo;
- Saba, Nabil;
- Diaz, Roberto
Publication type:
Article
Effectiveness and safety of cabazitaxel plus prednisolone chemotherapy for metastatic castration-resistant prostatic carcinoma: data on Korean patients obtained by the cabazitaxel compassionate-use program.
Published in:
Cancer Chemotherapy & Pharmacology, 2014, v. 74, n. 5, p. 1005, doi. 10.1007/s00280-014-2579-5
By:
- Lee, Jae-Lyun;
- Park, Se;
- Koh, Su-Jin;
- Lee, Se;
- Kim, Yu;
- Choi, Yoon;
- Lee, Jihye;
- Lim, Ho
Publication type:
Article
Significant association of combination of OCT4, NANOG, and SOX2 gene polymorphisms in susceptibility and response to treatment in North Indian breast cancer patients.
Published in:
Cancer Chemotherapy & Pharmacology, 2014, v. 74, n. 5, p. 1065, doi. 10.1007/s00280-014-2588-4
By:
- Tulsyan, Sonam;
- Agarwal, Gaurav;
- Lal, Punita;
- Mittal, Balraj
Publication type:
Article
A phase I, open-label, multicenter study to evaluate the pharmacokinetics and safety of oral panobinostat in patients with advanced solid tumors and various degrees of hepatic function.
Published in:
2014
By:
- Slingerland, Marije;
- Hess, Dagmar;
- Clive, Sally;
- Sharma, Sunil;
- Sandstrom, Per;
- Loman, Niklas;
- Porro, Maria;
- Mu, Song;
- Waldron, Edward;
- Valera, Sue-zette;
- Gelderblom, Hans
Publication type:
Report
Predicting success in regulatory approval from Phase I results.
Published in:
Cancer Chemotherapy & Pharmacology, 2014, v. 74, n. 5, p. 1099, doi. 10.1007/s00280-014-2596-4
By:
- Malik, Laeeq;
- Mejia, Alex;
- Parsons, Helen;
- Ehler, Benjamin;
- Mahalingam, Devalingam;
- Brenner, Andrew;
- Sarantopoulos, John;
- Weitman, Steven
Publication type:
Article
GEIS 2013 guidelines for gastrointestinal sarcomas (GIST).
Published in:
Cancer Chemotherapy & Pharmacology, 2014, v. 74, n. 5, p. 883, doi. 10.1007/s00280-014-2547-0
By:
- Poveda, Andrés;
- Muro, Xavier;
- López-Guerrero, Jose;
- Martínez, Virginia;
- Romero, Ignacio;
- Valverde, Claudia;
- Cubedo, Ricardo;
- Martín-Broto, Javier
Publication type:
Article