Works in Cancer Chemotherapy & Pharmacology, 2014, Vol 74, Issue 2

Results: 27

Frontline treatment with gemcitabine, oxaliplatin and erlotinib for the treatment of advanced or metastatic pancreatic cancer: a multicenter phase II study of the Hellenic Oncology Research Group (HORG)

Published in:

2014

By:

Katopodis, O;
Souglakos, J;
Stathopoulos, E;
Christopoulou, A;
Kontopodis, E;
Kotsakis, A;
Kalbakis, K;
Kentepozidis, N;
Polyzos, A;
Hatzidaki, D;
Georgoulias, V

Publication type:

Journal Article

Novel DNA methyltransferase-1 (DNMT1) depleting anticancer nucleosides, 4'-thio-2'-deoxycytidine and 5-aza-4'-thio-2'-deoxycytidine.

Published in:

2014

By:

Thottassery, Jaideep V;
Sambandam, Vijaya;
Allan, Paula W;
Maddry, Joseph A;
Maxuitenko, Yulia Y;
Tiwari, Kamal;
Hollingshead, Melinda;
Parker, William B

Publication type:

journal article

Third-space fluid distribution of pemetrexed in non-small cell lung cancer patients.

Published in:

Cancer Chemotherapy & Pharmacology, 2014, v. 74, n. 2, p. 349, doi. 10.1007/s00280-014-2485-x

By:

Honoré, Per;
Joensen, Sigrid;
Olsen, Michelle;
Hansen, Steen;
Mellemgaard, Anders

Publication type:

Article

Phase 1 dose-escalation study of the PARP inhibitor CEP-9722 as monotherapy or in combination with temozolomide in patients with solid tumors.

Published in:

Cancer Chemotherapy & Pharmacology, 2014, v. 74, n. 2, p. 257, doi. 10.1007/s00280-014-2486-9

By:

Plummer, Ruth;
Stephens, Peter;
Aissat-Daudigny, Louiza;
Cambois, Anne;
Moachon, Gilbert;
Brown, Peter;
Campone, Mario

Publication type:

Article

Cimetidine attenuates vinorelbine-induced phlebitis in mice by militating E-selectin expression.

Published in:

Cancer Chemotherapy & Pharmacology, 2014, v. 74, n. 2, p. 239, doi. 10.1007/s00280-014-2487-8

By:

Wang, Zhuo;
Ma, Lijuan;
Wang, Xuebin;
Cai, Heping;
Huang, Jin;
Liu, Jiyong;
Hu, Jinhong;
Su, Dingfeng

Publication type:

Article

Gastric cancer with para-aortic lymph node metastases: do not miss a chance of cure!

Published in:

2014

By:

Marrelli, Daniele;
Mazzei, Maria;
Roviello, Franco

Publication type:

Letter

A phase II study of metronomic paclitaxel/cyclophosphamide/capecitabine followed by 5-fluorouracil/epirubicin/cyclophosphamide as preoperative chemotherapy for triple-negative or low hormone receptor expressing/HER2-negative primary breast cancer.

Published in:

Cancer Chemotherapy & Pharmacology, 2014, v. 74, n. 2, p. 229, doi. 10.1007/s00280-014-2492-y

By:

Masuda, N.;
Higaki, K.;
Takano, T.;
Matsunami, N.;
Morimoto, T.;
Ohtani, S.;
Mizutani, M.;
Miyamoto, T.;
Kuroi, K.;
Ohno, S.;
Morita, S.;
Toi, M.

Publication type:

Article

A phase I study of pegylated liposomal doxorubicin and temsirolimus in patients with refractory solid malignancies.

Published in:

2014

By:

Wang-Gillam, Andrea;
Thakkar, Nilay;
Lockhart, A.;
Williams, Kerry;
Baggstrom, Maria;
Naughton, Michael;
Suresh, Rama;
Ma, Cynthia;
Tan, Benjamin;
Lee, Wooin;
Jiang, Xuntian;
Mwandoro, Tibu;
Trull, Lauren;
Belanger, Stefanie;
Creekmore, Allison;
Gao, Feng;
Fracasso, Paula;
Picus, Joel

Publication type:

Report

Role of pregnane X receptor in chemotherapeutic treatment.

Published in:

Cancer Chemotherapy & Pharmacology, 2014, v. 74, n. 2, p. 217, doi. 10.1007/s00280-014-2494-9

By:

Zhuo, Wei;
Hu, Lei;
Lv, Jinfeng;
Wang, Hongbing;
Zhou, Honghao;
Fan, Lan

Publication type:

Article

Differential regulation of bladder cancer growth by various glucocorticoids: corticosterone and prednisone inhibit cell invasion without promoting cell proliferation or reducing cisplatin cytotoxicity.

Published in:

Cancer Chemotherapy & Pharmacology, 2014, v. 74, n. 2, p. 249, doi. 10.1007/s00280-014-2496-7

By:

Ishiguro, Hitoshi;
Kawahara, Takashi;
Zheng, Yichun;
Kashiwagi, Eiji;
Li, Yi;
Miyamoto, Hiroshi

Publication type:

Article

Supplementation of fish oil augments efficacy and attenuates toxicity of 5-fluorouracil in 1,2-dimethylhydrazine dihydrochloride/dextran sulfate sodium-induced colon carcinogenesis.

Published in:

Cancer Chemotherapy & Pharmacology, 2014, v. 74, n. 2, p. 309, doi. 10.1007/s00280-014-2497-6

By:

Rani, Isha;
Vaiphei, Kim;
Agnihotri, Navneet

Publication type:

Article

A phase II trial of Cremorphor EL-free paclitaxel (Genexol-PM) and gemcitabine in patients with advanced non-small cell lung cancer.

Published in:

Cancer Chemotherapy & Pharmacology, 2014, v. 74, n. 2, p. 277, doi. 10.1007/s00280-014-2498-5

By:

Ahn, Hee;
Jung, Minkyu;
Sym, Sun;
Shin, Dong;
Kang, Shin;
Kyung, Sun;
Park, Jeong-Woong;
Jeong, Sung;
Cho, Eun

Publication type:

Article

Phase II trial of vatalanib in patients with advanced or metastatic pancreatic adenocarcinoma after first-line gemcitabine therapy (PCRT O4-001).

Published in:

Cancer Chemotherapy & Pharmacology, 2014, v. 74, n. 2, p. 379, doi. 10.1007/s00280-014-2499-4

By:

Dragovich, T.;
Laheru, D.;
Dayyani, F.;
Bolejack, V.;
Smith, L.;
Seng, J.;
Burris, H.;
Rosen, P.;
Hidalgo, M.;
Ritch, P.;
Baker, A.;
Raghunand, N.;
Crowley, J.;
Hoff, D.

Publication type:

Article

Population pharmacokinetics of trastuzumab emtansine (T-DM1), a HER2-targeted antibody-drug conjugate, in patients with HER2-positive metastatic breast cancer: clinical implications of the effect of covariates.

Published in:

Cancer Chemotherapy & Pharmacology, 2014, v. 74, n. 2, p. 399, doi. 10.1007/s00280-014-2500-2

By:

Lu, Dan;
Girish, Sandhya;
Gao, Yuying;
Wang, Bei;
Yi, Joo-Hee;
Guardino, Ellie;
Samant, Meghna;
Cobleigh, Melody;
Rimawi, Mothaffar;
Conte, Pierfranco;
Jin, Jin

Publication type:

Article

Evaluation of the effect of food and ketoconazole on the pharmacokinetics of the smoothened inhibitor PF-04449913 in healthy volunteers.

Published in:

Cancer Chemotherapy & Pharmacology, 2014, v. 74, n. 2, p. 411, doi. 10.1007/s00280-014-2502-0

By:

Shaik, M.;
LaBadie, Robert;
Rudin, Dan;
Levin, Wendy

Publication type:

Article

Novel DNA methyltransferase-1 (DNMT1) depleting anticancer nucleosides, 4′-thio-2′-deoxycytidine and 5-aza-4′-thio-2′-deoxycytidine.

Published in:

Cancer Chemotherapy & Pharmacology, 2014, v. 74, n. 2, p. 291, doi. 10.1007/s00280-014-2503-z

By:

Thottassery, Jaideep;
Sambandam, Vijaya;
Allan, Paula;
Maddry, Joseph;
Maxuitenko, Yulia;
Tiwari, Kamal;
Hollingshead, Melinda;
Parker, William

Publication type:

Article

Enhanced skin toxicity associated with the combination of clofarabine plus cytarabine for the treatment of acute leukemia.

Published in:

Cancer Chemotherapy & Pharmacology, 2014, v. 74, n. 2, p. 303, doi. 10.1007/s00280-014-2504-y

By:

Zhang, Bingnan;
Bolognia, Jean;
Marks, Peter;
Podoltsev, Nikolai

Publication type:

Article

Hypothyroidism as a potential biomarker of efficacy of famitinib, a novel VEGFR-2 inhibitor in metastatic breast cancer.

Published in:

Cancer Chemotherapy & Pharmacology, 2014, v. 74, n. 2, p. 389, doi. 10.1007/s00280-014-2505-x

By:

Cao, Jun;
Zhang, Jian;
Wang, Zhonghua;
Wang, Biyun;
Lv, Fangfang;
Wang, Leiping;
Hu, Xichun

Publication type:

Article

Comparative pharmacokinetic/pharmacodynamic characterisation of a new pegylated recombinant E. coli l-asparaginase preparation (MC0609) in Beagle dog.

Published in:

Cancer Chemotherapy & Pharmacology, 2014, v. 74, n. 2, p. 367, doi. 10.1007/s00280-014-2506-9

By:

Borghorst, Stephan;
Hempel, Georg;
Poppenborg, Sabine;
Franke, Dieter;
König, Thorsten;
Baumgart, Joachim

Publication type:

Article

Influence of genetic polymorphisms of FPGS, GGH, and MTHFR on serum methotrexate levels in Chinese children with acute lymphoblastic leukemia.

Published in:

Cancer Chemotherapy & Pharmacology, 2014, v. 74, n. 2, p. 283, doi. 10.1007/s00280-014-2507-8

By:

Wang, Shu-mei;
Sun, Lu-lu;
Zeng, Wei-xin;
Wu, Wan-shui;
Zhang, Guo-liang

Publication type:

Article

Circulating biomarkers in hepatocellular carcinoma.

Published in:

Cancer Chemotherapy & Pharmacology, 2014, v. 74, n. 2, p. 323, doi. 10.1007/s00280-014-2508-7

By:

Morris, Karen;
Tugwood, Jonathan;
Khoja, Leila;
Lancashire, Matthew;
Sloane, Robert;
Burt, Debbie;
Shenjere, Patrick;
Zhou, Cong;
Hodgson, Clare;
Ohtomo, Toshihiko;
Katoh, Atsuhiko;
Ishiguro, Takahiro;
Valle, Juan;
Dive, Caroline

Publication type:

Article

Frontline treatment with gemcitabine, oxaliplatin and erlotinib for the treatment of advanced or metastatic pancreatic cancer: a multicenter phase II study of the Hellenic Oncology Research Group (HORG).

Published in:

Cancer Chemotherapy & Pharmacology, 2014, v. 74, n. 2, p. 333, doi. 10.1007/s00280-014-2509-6

By:

Katopodis, O.;
Souglakos, J.;
Stathopoulos, E.;
Christopoulou, A.;
Kontopodis, E.;
Kotsakis, A.;
Kalbakis, K.;
Kentepozidis, N.;
Polyzos, A.;
Hatzidaki, D.;
Georgoulias, V.

Publication type:

Article

Impact of patient ethnicity on the metabolic and immunologic effects of PI3K-mTOR pathway inhibition in patients with solid tumor malignancies.

Published in:

Cancer Chemotherapy & Pharmacology, 2014, v. 74, n. 2, p. 359, doi. 10.1007/s00280-014-2510-0

By:

Aggarwal, Rahul;
Grabowsky, Jennifer;
Strait, Noah;
Cockerill, Alyson;
Munster, Pamela

Publication type:

Article

Evaluation of pharmacokinetics and safety of ponatinib in subjects with chronic hepatic impairment and matched healthy subjects.

Published in:

Cancer Chemotherapy & Pharmacology, 2014, v. 74, n. 2, p. 341, doi. 10.1007/s00280-014-2511-z

By:

Narasimhan, Narayana;
Dorer, David;
Davis, Jeffrey;
Turner, Christopher;
Marbury, Thomas;
Sonnichsen, Daryl

Publication type:

Article

Gastric cancer with para-aortic lymph nodes metastasis: curable dissection possible but be cautiously selected.

Published in:

2014

By:

Liu, Tianshu;
Sun, Yihong;
Wang, Yan

Publication type:

Letter

In vitro testing of drug combinations employing nilotinib and alkylating agents with regard to pretransplant conditioning treatment of advanced-phase chronic myeloid leukemia.

Published in:

Cancer Chemotherapy & Pharmacology, 2014, v. 74, n. 2, p. 427, doi. 10.1007/s00280-014-2533-6

By:

Radujkovic, Aleksandar;
Luft, Thomas;
Dreger, Peter;
Ho, Anthony;
Jens Zeller, W.;
Fruehauf, Stefan;
Topaly, Julian

Publication type:

Article

Pharmacokinetics of afatinib in subjects with mild or moderate hepatic impairment.

Published in:

Cancer Chemotherapy & Pharmacology, 2014, v. 74, n. 2, p. 267, doi. 10.1007/s00280-014-2484-y

By:

Schnell, David;
Buschke, Susanne;
Fuchs, Holger;
Gansser, Dietmar;
Goeldner, Rainer-Georg;
Uttenreuther-Fischer, Martina;
Stopfer, Peter;
Wind, Sven;
Petersen-Sylla, Marc;
Halabi, Atef;
Koenen, Rüdiger

Publication type:

Article