Works in Cancer Chemotherapy & Pharmacology, 2011, Vol 68, Issue 6

Results: 53

Chemotherapy for endometrial carcinoma (GOGO-EM1 study): TEC (paclitaxel, epirubicin, and carboplatin) is an effective remission-induction and adjuvant therapy.

Published in:

2011

By:

Egawa-Takata T;
Ueda Y;
Kuragaki C;
Miyake T;
Miyatake T;
Fujita M;
Yoshino K;
Nakashima R;
Okazawa M;
Tsutsui T;
Morishige K;
Kimura T;
Yamasaki M;
Nishizaki T;
Nagamatsu M;
Ito K;
Asada M;
Ogita K;
Wakimoto A;
Yamamoto T

Publication type:

Journal Article

Impact of plasma and intracellular exposure and CYP3A4, CYP3A5, and ABCB1 genetic polymorphisms on vincristine-induced neurotoxicity.

Published in:

2011

By:

Guilhaumou R;
Solas C;
Bourgarel-Rey V;
Quaranta S;
Rome A;
Simon N;
Lacarelle B;
Andre N

Publication type:

Journal Article

Pharmacokinetics of orally administered uracil in healthy volunteers and in DPD-deficient patients, a possible tool for screening of DPD deficiency.

Published in:

2011

By:

van Staveren MC;
Theeuwes-Oonk B;
Guchelaar HJ;
van Kuilenburg AB;
Maring JG;
van Staveren, Maurice C;
Theeuwes-Oonk, Barbara;
Guchelaar, Henk Jan;
van Kuilenburg, André B P;
Maring, Jan Gerard

Publication type:

journal article

Sorafenib for hepatocellular carcinoma according to Child-Pugh class of liver function.

Published in:

2011

By:

Farinati F;
Giacomin A;
Vanin V

Publication type:

Journal Article

Preclinical evaluation of the novel multi-targeted agent R1530.

Published in:

2011

By:

Kolinsky K;
Tovar C;
Zhang YE;
Railkar A;
Yang H;
Carvajal D;
Nevins T;
Geng W;
Linn M;
Packman K;
Liu JJ;
Zhang Z;
Wovkulich P;
Ju G;
Higgins B

Publication type:

Journal Article

Tesetaxel, a new oral taxane, in combination with capecitabine: a phase I, dose-escalation study in patients with advanced solid tumors.

Published in:

2011

By:

Saif MW;
Sarantopoulos J;
Patnaik A;
Tolcher AW;
Takimoto C;
Beeram M

Publication type:

Journal Article

Pulmonary toxicity among cancer patients treated with a combination of docetaxel and gemcitabine: a meta-analysis of clinical trials.

Published in:

2011

By:

Binder D;
Hübner RH;
Temmesfeld-Wollbrück B;
Schlattmann P

Publication type:

Journal Article

Sorafenib augments cytotoxic effect of S-1 in vitro and in vivo through TS suppression.

Published in:

2011

By:

Takeuchi A;
Shiota M;
Tatsugami K;
Yokomizo A;
Eto M;
Inokuchi J;
Kuroiwa K;
Kiyoshima K;
Naito S

Publication type:

Journal Article

Pharmacokinetic evaluation of the vinorelbine-lapatinib combination in the treatment of breast cancer patients.

Published in:

2011

By:

Rezai K;
Urien S;
Isambert N;
Roche H;
Dieras V;
Berille J;
Bonneterre J;
Brain E;
Lokiec F

Publication type:

Journal Article

Prevention of cisplatin-induced hearing loss by administration of a thiosulfate-containing gel to the middle ear in a guinea pig model.

Published in:

2011

By:

Berglin CE;
Pierre PV;
Bramer T;
Edsman K;
Ehrsson H;
Eksborg S;
Laurell G

Publication type:

Journal Article

Comparison of different semi-mechanistic models for chemotherapy-related neutropenia: application to BI 2536 a Plk-1 inhibitor.

Published in:

2011

By:

Soto E;
Staab A;
Doege C;
Freiwald M;
Munzert G;
Trocóniz IF

Publication type:

Journal Article

The effect of different etiologies of hepatic impairment on the pharmacokinetics of gefitinib.

Published in:

2011

By:

Horak J;
White J;
Harris AL;
Verrill M;
Carmichael J;
Holt A;
Cantarini M;
Macpherson M;
Swaisland A;
Swaisland H;
Twelves C

Publication type:

Journal Article

Weekly docetaxel and cisplatin with concomitant radiotherapy in addition to surgery and/or consolidation chemotherapy in stage III non-small cell lung cancer.

Published in:

2011

By:

Sen F;
Saglam EK;
Toker A;
Dilege S;
Kizir A;
Oral EN;
Saip P;
Sakallioglu B;
Topuz E;
Aydiner A

Publication type:

Journal Article

Triweekly reduced-dose docetaxel combined with cisplatin in recurrent/metastatic head and neck squamous cell carcinoma: a multicenter phase II study.

Published in:

2011

By:

Chang PM;
Tzeng CH;
Chen MH;
Tsao CJ;
Su WC;
Hwang WS;
Chang YF;
Chang SY;
Yang MH

Publication type:

Journal Article

Quercetin enhances 5-fluorouracil-induced apoptosis in MSI colorectal cancer cells through p53 modulation.

Published in:

2011

By:

Xavier CP;
Lima CF;
Rohde M;
Pereira-Wilson C

Publication type:

Journal Article

Bevacizumab plus gemcitabine and oxaliplatin as first-line therapy for metastatic or locally advanced pancreatic cancer: a phase II trial.

Published in:

2011

By:

Fogelman D;
Jafari M;
Varadhachary GR;
Xiong H;
Bullock S;
Ozer H;
Lin E;
Morris J;
Cunningham P;
Bennett B;
Abbruzzese JL;
Wolff RA

Publication type:

Journal Article

Dihydroartemisinin inhibits angiogenesis in pancreatic cancer by targeting the NF-κB pathway.

Published in:

2011

By:

Wang SJ;
Sun B;
Cheng ZX;
Zhou HX;
Gao Y;
Kong R;
Chen H;
Jiang HC;
Pan SH;
Xue DB;
Bai XW;
Wang, Shuang-Jia;
Sun, Bei;
Cheng, Zhuo-Xin;
Zhou, Hao-Xin;
Gao, Yue;
Kong, Rui;
Chen, Hua;
Jiang, Hong-Chi;
Pan, Shang-Ha

Publication type:

journal article

Carboplatin plus pemetrexed for platinum-pretreated, advanced non-small cell lung cancer: a retrospective study with pharmacogenetic evaluation.

Published in:

2011

By:

Metro G;
Chiari R;
Mare M;
Giannarelli D;
Tofanetti FR;
Minotti V;
Ferraldeschi M;
Giuffrida D;
Marcomigni L;
Bennati C;
Fischer MJ;
Meacci M;
Bellavita R;
Pistola L;
Ludovini V;
Crinò L

Publication type:

Journal Article

Spisulosine (ES-285) given as a weekly three-hour intravenous infusion: results of a phase I dose-escalating study in patients with advanced solid malignancies.

Published in:

2011

By:

Schöffski P;
Dumez H;
Ruijter R;
Miguel-Lillo B;
Soto-Matos A;
Alfaro V;
Giaccone G

Publication type:

Journal Article

t(11;18)(q21;q21) translocation as predictive marker for non-responsiveness to salvage thalidomide therapy in patients with marginal zone B-cell lymphoma with gastric involvement.

Published in:

2011

By:

Kuo SH;
Cheng AL;
Lin CW;
Hsu CH;
Wu MS;
Yeh KH;
Tzeng YS;
Chen LT

Publication type:

Journal Article

Lack of food effect on single-dose pharmacokinetics of brivanib, and safety and efficacy following multiple doses in subjects with advanced or metastatic solid tumors.

Published in:

2011

By:

Lorusso P;
Shapiro GI;
Hurwitz H;
Pilat MJ;
Chemidlin J;
Kollia G;
Syed S;
Fischer B;
Masson E

Publication type:

Journal Article

Lack of food effect on single-dose pharmacokinetics of brivanib, and safety and efficacy following multiple doses in subjects with advanced or metastatic solid tumors.

Published in:

Cancer Chemotherapy & Pharmacology, 2011, v. 68, n. 6, p. 1377, doi. 10.1007/s00280-011-1603-2

By:

LoRusso, Patricia;
Shapiro, Geoffrey;
Hurwitz, Herbert;
Pilat, Mary;
Chemidlin, Janice;
Kollia, Georgia;
Syed, Shariq;
Fischer, Bruce;
Masson, Eric

Publication type:

Article

Spisulosine (ES-285) given as a weekly three-hour intravenous infusion: results of a phase I dose-escalating study in patients with advanced solid malignancies.

Published in:

Cancer Chemotherapy & Pharmacology, 2011, v. 68, n. 6, p. 1397, doi. 10.1007/s00280-011-1612-1

By:

Schöffski, P.;
Dumez, H.;
Ruijter, R.;
Miguel-Lillo, B.;
Soto-Matos, A.;
Alfaro, V.;
Giaccone, G.

Publication type:

Article

Carboplatin plus pemetrexed for platinum-pretreated, advanced non-small cell lung cancer: a retrospective study with pharmacogenetic evaluation.

Published in:

Cancer Chemotherapy & Pharmacology, 2011, v. 68, n. 6, p. 1405, doi. 10.1007/s00280-011-1632-x

By:

Metro, Giulio;
Chiari, R.;
Mare, M.;
Giannarelli, D.;
Tofanetti, F.;
Minotti, V.;
Ferraldeschi, M.;
Giuffrida, D.;
Marcomigni, L.;
Bennati, C.;
Fischer, M.;
Meacci, M.;
Bellavita, R.;
Pistola, L.;
Ludovini, V.;
Crinò, L.

Publication type:

Article

t(11;18)(q21;q21) translocation as predictive marker for non-responsiveness to salvage thalidomide therapy in patients with marginal zone B-cell lymphoma with gastric involvement.

Published in:

Cancer Chemotherapy & Pharmacology, 2011, v. 68, n. 6, p. 1387, doi. 10.1007/s00280-011-1631-y

By:

Kuo, Sung-Hsin;
Cheng, Ann-Lii;
Lin, Chung-Wu;
Hsu, Chih-Hung;
Wu, Ming-Shiang;
Yeh, Kun-Huei;
Tzeng, Yi-Shin;
Chen, Li-Tzong

Publication type:

Article

Tumor growth modeling from clinical trials reveals synergistic anticancer effect of the capecitabine and docetaxel combination in metastatic breast cancer.

Published in:

Cancer Chemotherapy & Pharmacology, 2011, v. 68, n. 6, p. 1413, doi. 10.1007/s00280-011-1628-6

By:

Frances, N.;
Claret, L.;
Bruno, R.;
Iliadis, A.

Publication type:

Article

Dihydroartemisinin inhibits angiogenesis in pancreatic cancer by targeting the NF-κB pathway.

Published in:

Cancer Chemotherapy & Pharmacology, 2011, v. 68, n. 6, p. 1421, doi. 10.1007/s00280-011-1643-7

By:

Wang, Shuang-Jia;
Sun, Bei;
Cheng, Zhuo-Xin;
Zhou, Hao-Xin;
Gao, Yue;
Kong, Rui;
Chen, Hua;
Jiang, Hong-Chi;
Pan, Shang-Ha;
Xue, Dong-Bo;
Bai, Xue-Wei

Publication type:

Article

Bevacizumab plus gemcitabine and oxaliplatin as first-line therapy for metastatic or locally advanced pancreatic cancer: a phase II trial.

Published in:

Cancer Chemotherapy & Pharmacology, 2011, v. 68, n. 6, p. 1431, doi. 10.1007/s00280-011-1601-4

By:

Fogelman, David;
Jafari, Mehrdad;
Varadhachary, Gauri;
Xiong, Henry;
Bullock, Susie;
Ozer, Harold;
Lin, E.;
Morris, Jeffrey;
Cunningham, Patti;
Bennett, Bronwyn;
Abbruzzese, James;
Wolff, Robert

Publication type:

Article

Dose-escalating and pharmacological study of bortezomib in adult cancer patients with impaired renal function: a National Cancer Institute Organ Dysfunction Working Group Study.

Published in:

Cancer Chemotherapy & Pharmacology, 2011, v. 68, n. 6, p. 1439, doi. 10.1007/s00280-011-1637-5

By:

Leal, Ticiana;
Remick, Scot;
Takimoto, Chris;
Ramanathan, Ramesh;
Davies, Angela;
Egorin, Merrill;
Hamilton, Anne;
LoRusso, Patricia;
Shibata, Stephen;
Lenz, Heinz-Josef;
Mier, James;
Sarantopoulos, John;
Mani, Sridhar;
Wright, John;
Ivy, S.;
Neuwirth, Rachel;
Moltke, Lisa;
Venkatakrishnan, Karthik;
Mulkerin, Daniel

Publication type:

Article

Quercetin enhances 5-fluorouracil-induced apoptosis in MSI colorectal cancer cells through p53 modulation.

Published in:

Cancer Chemotherapy & Pharmacology, 2011, v. 68, n. 6, p. 1449, doi. 10.1007/s00280-011-1641-9

By:

Xavier, Cristina;
Lima, Cristovao;
Rohde, Mikkel;
Pereira-Wilson, Cristina

Publication type:

Article

Resveratrol induces SIRT1- and energy-stress-independent inhibition of tumor cell regrowth after low-dose platinum treatment.

Published in:

Cancer Chemotherapy & Pharmacology, 2011, v. 68, n. 6, p. 1459, doi. 10.1007/s00280-011-1640-x

By:

Björklund, My;
Roos, Jeanette;
Gogvadze, Vladimir;
Shoshan, Maria

Publication type:

Article

Triweekly reduced-dose docetaxel combined with cisplatin in recurrent/metastatic head and neck squamous cell carcinoma: a multicenter phase II study.

Published in:

Cancer Chemotherapy & Pharmacology, 2011, v. 68, n. 6, p. 1477, doi. 10.1007/s00280-011-1645-5

By:

Chang, Peter;
Tzeng, Cheng-Hwai;
Chen, Ming-Huang;
Tsao, Chao-Jung;
Su, Wu-Chou;
Hwang, Wei-Shuo;
Chang, Yi-Fang;
Chang, Shyue-Yih;
Yang, Muh-Hwa

Publication type:

Article

Preclinical evaluation of lestaurtinib (CEP-701) in combination with retinoids for neuroblastoma.

Published in:

Cancer Chemotherapy & Pharmacology, 2011, v. 68, n. 6, p. 1469, doi. 10.1007/s00280-011-1623-y

By:

Norris, Robin;
Minturn, Jane;
Brodeur, Garrett;
Maris, John;
Adamson, Peter

Publication type:

Article

The effect of different etiologies of hepatic impairment on the pharmacokinetics of gefitinib.

Published in:

Cancer Chemotherapy & Pharmacology, 2011, v. 68, n. 6, p. 1485, doi. 10.1007/s00280-011-1611-2

By:

Horak, Jiri;
White, Jeff;
Harris, Adrian;
Verrill, Mark;
Carmichael, James;
Holt, Alison;
Cantarini, Mireille;
Macpherson, Merran;
Swaisland, Alan;
Swaisland, Helen;
Twelves, Chris

Publication type:

Article

Weekly docetaxel and cisplatin with concomitant radiotherapy in addition to surgery and/or consolidation chemotherapy in stage III non-small cell lung cancer.

Published in:

Cancer Chemotherapy & Pharmacology, 2011, v. 68, n. 6, p. 1497, doi. 10.1007/s00280-011-1642-8

By:

Sen, Fatma;
Saglam, Esra;
Toker, Alper;
Dilege, Sukru;
Kizir, Ahmet;
Oral, Ethem;
Saip, Pinar;
Sakallioglu, Barkin;
Topuz, Erkan;
Aydiner, Adnan

Publication type:

Article

Pharmacokinetics and antitumor activity of patupilone combined with midazolam or omeprazole in patients with advanced cancer.

Published in:

Cancer Chemotherapy & Pharmacology, 2011, v. 68, n. 6, p. 1507, doi. 10.1007/s00280-011-1635-7

By:

Tsimberidou, Apostolia-Maria;
Lewis, Nancy;
Reid, Tony;
Burris, Howard;
Urban, Patrick;
Tan, Eugene;
Anand, Suraj;
Uehara, Cynthia;
Kurzrock, Razelle

Publication type:

Article

Comparison of different semi-mechanistic models for chemotherapy-related neutropenia: application to BI 2536 a Plk-1 inhibitor.

Published in:

Cancer Chemotherapy & Pharmacology, 2011, v. 68, n. 6, p. 1517, doi. 10.1007/s00280-011-1647-3

By:

Soto, Elena;
Staab, Alexander;
Doege, Christiane;
Freiwald, Matthias;
Munzert, Gerd;
Trocóniz, Iñaki

Publication type:

Article

Pharmacokinetic evaluation of the vinorelbine-lapatinib combination in the treatment of breast cancer patients.

Published in:

Cancer Chemotherapy & Pharmacology, 2011, v. 68, n. 6, p. 1529, doi. 10.1007/s00280-011-1650-8

By:

Rezai, Keyvan;
Urien, S.;
Isambert, N.;
Roche, H.;
Dieras, V.;
Berille, J.;
Bonneterre, J.;
Brain, E.;
Lokiec, F.

Publication type:

Article

Erufosine, an alkylphosphocholine, with differential toxicity to human cancer cells and bone marrow cells.

Published in:

Cancer Chemotherapy & Pharmacology, 2011, v. 68, n. 6, p. 1537, doi. 10.1007/s00280-011-1658-0

By:

Bagley, Rebecca;
Kurtzberg, Leslie;
Rouleau, Cecile;
Yao, Min;
Teicher, Beverly

Publication type:

Article

Prevention of cisplatin-induced hearing loss by administration of a thiosulfate-containing gel to the middle ear in a guinea pig model.

Published in:

Cancer Chemotherapy & Pharmacology, 2011, v. 68, n. 6, p. 1547, doi. 10.1007/s00280-011-1656-2

By:

Berglin, Cecilia;
Pierre, Pernilla;
Bramer, Tobias;
Edsman, Katarina;
Ehrsson, Hans;
Eksborg, Staffan;
Laurell, Göran

Publication type:

Article

Sorafenib augments cytotoxic effect of S-1 in vitro and in vivo through TS suppression.

Published in:

Cancer Chemotherapy & Pharmacology, 2011, v. 68, n. 6, p. 1557, doi. 10.1007/s00280-011-1660-6

By:

Takeuchi, Ario;
Shiota, Masaki;
Tatsugami, Katsunori;
Yokomizo, Akira;
Eto, Masatoshi;
Inokuchi, Junichi;
Kuroiwa, Kentaro;
Kiyoshima, Keijiro;
Naito, Seiji

Publication type:

Article

Tesetaxel, a new oral taxane, in combination with capecitabine: a phase I, dose-escalation study in patients with advanced solid tumors.

Published in:

Cancer Chemotherapy & Pharmacology, 2011, v. 68, n. 6, p. 1565, doi. 10.1007/s00280-011-1639-3

By:

Saif, Muhammad;
Sarantopoulos, John;
Patnaik, Amita;
Tolcher, Anthony;
Takimoto, Chris;
Beeram, Murali

Publication type:

Article

Pulmonary toxicity among cancer patients treated with a combination of docetaxel and gemcitabine: a meta-analysis of clinical trials.

Published in:

Cancer Chemotherapy & Pharmacology, 2011, v. 68, n. 6, p. 1575, doi. 10.1007/s00280-011-1648-2

By:

Binder, Daniel;
Hübner, Ralf-Harto;
Temmesfeld-Wollbrück, Bettina;
Schlattmann, Peter

Publication type:

Article

Preclinical evaluation of the novel multi-targeted agent R1530.

Published in:

Cancer Chemotherapy & Pharmacology, 2011, v. 68, n. 6, p. 1585, doi. 10.1007/s00280-011-1608-x

By:

Kolinsky, Kenneth;
Tovar, Christian;
Zhang, Yu-E;
Railkar, Aruna;
Yang, Hong;
Carvajal, Daisy;
Nevins, Thomas;
Geng, Wanping;
Linn, Michael;
Packman, Kathryn;
Liu, Jin-Jun;
Zhang, Zhuming;
Wovkulich, Peter;
Ju, Grace;
Higgins, Brian

Publication type:

Article

A phase II trial of gemcitabine and capecitabine in patients with unresectable or metastatic gallbladder cancer or cholangiocarcinoma: Southwest Oncology Group study S0202.

Published in:

Cancer Chemotherapy & Pharmacology, 2011, v. 68, n. 6, p. 1595, doi. 10.1007/s00280-011-1657-1

By:

Iqbal, Syma;
Rankin, Cathryn;
Lenz, Heinz-Josef;
Gold, Philip;
Ahmad, Syed;
El-Khoueiry, Anthony;
Messino, Michael;
Holcombe, Randall;
Blanke, Charles

Publication type:

Article

Chemotherapy for endometrial carcinoma (GOGO-EM1 study): TEC (paclitaxel, epirubicin, and carboplatin) is an effective remission-induction and adjuvant therapy.

Published in:

Cancer Chemotherapy & Pharmacology, 2011, v. 68, n. 6, p. 1603, doi. 10.1007/s00280-011-1638-4

By:

Egawa-Takata, Tomomi;
Ueda, Yutaka;
Kuragaki, Chie;
Miyake, Takahito;
Miyatake, Takashi;
Fujita, Masami;
Yoshino, Kiyoshi;
Nakashima, Ryuichi;
Okazawa, Mika;
Tsutsui, Tateki;
Morishige, Ken-Ichirou;
Kimura, Tadashi;
Yamasaki, Masato;
Nishizaki, Takamichi;
Nagamatsu, Masaaki;
Ito, Kimihiko;
Asada, Masahiro;
Ogita, Kazuhide;
Wakimoto, Akinori;
Yamamoto, Toshiya

Publication type:

Article

Pharmacokinetics of orally administered uracil in healthy volunteers and in DPD-deficient patients, a possible tool for screening of DPD deficiency.

Published in:

Cancer Chemotherapy & Pharmacology, 2011, v. 68, n. 6, p. 1611, doi. 10.1007/s00280-011-1661-5

By:

Staveren, Maurice;
Theeuwes-Oonk, Barbara;
Guchelaar, Henk;
Kuilenburg, André;
Maring, Jan

Publication type:

Article

The effect of thalidomide on the pharmacokinetics of irinotecan and metabolites in advanced solid tumor patients.

Published in:

Cancer Chemotherapy & Pharmacology, 2011, v. 68, n. 6, p. 1629, doi. 10.1007/s00280-011-1727-4

By:

Ramírez, Jacqueline;
Wu, Kehua;
Janisch, Linda;
Karrison, Theodore;
House, Larry;
Innocenti, Federico;
Cohen, Ezra;
Ratain, Mark

Publication type:

Article

Translational research of a novel humanized epidermal growth factor receptor-related protein: a putative inhibitor of pan-ErbB.

Published in:

Cancer Chemotherapy & Pharmacology, 2011, v. 68, n. 6, p. 1373, doi. 10.1007/s00280-011-1748-z

By:

Fu, Xian-Hua;
Li, Jun;
Huang, Jian-Jin;
Zheng, Shu;
Zhang, Su-Zhan

Publication type:

Article

A phase I, open-label, randomized crossover study to assess the effect of dosing of the MEK 1/2 inhibitor Selumetinib (AZD6244; ARRY-142866) in the presence and absence of food in patients with advanced solid tumors.

Published in:

2011

By:

Leijen, Suzanne;
Soetekouw, Patricia;
Jeffry Evans, T.;
Nicolson, Marianne;
Schellens, Jan;
Learoyd, Maria;
Grinsted, Lynda;
Zazulina, Victoria;
Pwint, Thinn;
Middleton, Mark

Publication type:

Report