Works in Cancer Chemotherapy & Pharmacology, 2011, Vol 68, Issue 5

Results: 52

A phase I-II study of elacytarabine (CP-4055) in the treatment of patients with ovarian cancer resistant or refractory to platinum therapy.
Published in:
2011
By:
- Pignata S;
- Amant F;
- Scambia G;
- Sorio R;
- Breda E;
- Rasch W;
- Hernes K;
- Pisano C;
- Leunen K;
- Lorusso D;
- Cannella L;
- Vergote I
Publication type:
Journal Article
MTHFR 677TT genotype and toxicity of methotrexate: controversial results.
Published in:
2011
By:
- Lopez-Lopez E;
- Ballesteros J;
- Garcia-Orad A
Publication type:
Journal Article
Methotrexate toxicity and efficacy during the consolidation phase in paediatric acute lymphoblastic leukaemia and MTHFR polymorphisms as pharmacogenetic determinants.
Published in:
2011
By:
- D'Angelo V;
- Ramaglia M;
- Iannotta A;
- Crisci S;
- Indolfi P;
- Francese M;
- Affinita MC;
- Pecoraro G;
- Napolitano A;
- Fusco C;
- Oreste M;
- Indolfi C;
- Casale F
Publication type:
Journal Article
Amrubicin for the treatment of neuroendocrine carcinoma of the gastrointestinal tract: a retrospective analysis of five cases.
Published in:
2011
By:
- Asayama M;
- Fuse N;
- Yoshino T;
- Yano T;
- Tahara M;
- Doi T;
- Fujii S;
- Ohtsu A
Publication type:
Journal Article
A phase 2 study of weekly albumin-bound paclitaxel (Abraxane®) given as a two-hour infusion.
Published in:
2011
By:
- Paik PK;
- James LP;
- Riely GJ;
- Azzoli CG;
- Miller VA;
- Ng KK;
- Sima CS;
- Heelan RT;
- Kris MG;
- Moore E;
- Rizvi NA;
- Paik, Paul K;
- James, Leonard P;
- Riely, Gregory J;
- Azzoli, Christopher G;
- Miller, Vincent A;
- Ng, Kenneth K;
- Sima, Camelia S;
- Heelan, Robert T;
- Kris, Mark G
Publication type:
journal article
Furanodienone induces cell cycle arrest and apoptosis by suppressing EGFR/HER2 signaling in HER2-overexpressing human breast cancer cells.
Published in:
2011
By:
- Li YW;
- Zhu GY;
- Shen XL;
- Chu JH;
- Yu ZL;
- Fong WF
Publication type:
Journal Article
Pre-treatment lymphopenia as a prognostic biomarker in colorectal cancer patients receiving chemotherapy.
Published in:
2011
By:
- Cézé N;
- Thibault G;
- Goujon G;
- Viguier J;
- Watier H;
- Dorval E;
- Lecomte T
Publication type:
Journal Article
Role of 12-lipoxygenase in regulation of ovarian cancer cell proliferation and survival.
Published in:
2011
By:
- Guo AM;
- Liu X;
- Al-Wahab Z;
- Maddippati KR;
- Ali-Fehmi R;
- Scicli AG;
- Munkarah AR
Publication type:
Journal Article
Pharmacologic and phenotypic study of docetaxel in patients with ovarian or primary peritoneal cancer.
Published in:
2011
By:
- Zamboni WC;
- Combest AJ;
- Deloia JA;
- Edwards RP;
- Bridges AS;
- Zamboni BA;
- Walko CM;
- Yu AY;
- Krivak TC;
- Kelley JL
Publication type:
Journal Article
A phase I study of tasisulam sodium (LY573636 sodium), a novel anticancer compound in patients with refractory solid tumors.
Published in:
2011
By:
- Simon GR;
- Ilaria RL Jr;
- Sovak MA;
- Williams CC;
- Haura EB;
- Cleverly AL;
- Sykes AK;
- Wagner MM;
- de Alwis DP;
- Slapak CA;
- Miller MA;
- Spriggs DR;
- Simon, George R;
- Ilaria, Robert L Jr;
- Sovak, Mika A;
- Williams, Charles C;
- Haura, Eric B;
- Cleverly, Ann L;
- Sykes, Amanda K;
- Wagner, Margaret M
Publication type:
journal article
A novel method for quantification of gemcitabine and its metabolites 2',2'-difluorodeoxyuridine and gemcitabine triphosphate in tumour tissue by LC-MS/MS: comparison with (19)F NMR spectroscopy.
Published in:
2011
By:
- Bapiro TE;
- Richards FM;
- Goldgraben MA;
- Olive KP;
- Madhu B;
- Frese KK;
- Cook N;
- Jacobetz MA;
- Smith DM;
- Tuveson DA;
- Griffiths JR;
- Jodrell DI;
- Bapiro, Tashinga E;
- Richards, Frances M;
- Goldgraben, Mae A;
- Olive, Kenneth P;
- Madhu, Basetti;
- Frese, Kristopher K;
- Cook, Natalie;
- Jacobetz, Michael A
Publication type:
journal article
Phase II study of FOLFOX4 with 'wait and go' strategy as first-line treatment for metastatic colorectal cancer.
Published in:
2011
By:
- Kochi M;
- Ichikawa W;
- Meguro E;
- Shibata H;
- Fukui T;
- Nagase M;
- Hoshino Y;
- Takeuchi M;
- Fujii M;
- Nakajima T
Publication type:
Journal Article
A multicenter, randomized, open-label study to assess the steady-state pharmacokinetics of bevacizumab given with either XELOX or FOLFOX-4 in patients with metastatic colorectal cancer.
Published in:
2011
By:
- Zhi J;
- Chen E;
- Major P;
- Burns I;
- Robinson B;
- McKendrick J;
- Rittweger K;
- Abt M;
- Goldstein D
Publication type:
Journal Article
Bevacizumab-related arterial hypertension as a predictive marker in metastatic colorectal cancer patients.
Published in:
2011
By:
- De Stefano A;
- Carlomagno C;
- Pepe S;
- Bianco R;
- De Placido S
Publication type:
Journal Article
Population pharmacokinetics and pharmacogenetics of vincristine in paediatric patients treated for solid tumour diseases.
Published in:
2011
By:
- Guilhaumou R;
- Simon N;
- Quaranta S;
- Verschuur A;
- Lacarelle B;
- Andre N;
- Solas C
Publication type:
Journal Article
Interaction of sorafenib and cytochrome P450 isoenzymes in patients with advanced melanoma: a phase I/II pharmacokinetic interaction study.
Published in:
2011
By:
- Flaherty KT;
- Lathia C;
- Frye RF;
- Schuchter L;
- Redlinger M;
- Rosen M;
- O'Dwyer PJ
Publication type:
Journal Article
Phase I trial of metronomic oral vinorelbine in patients with advanced cancer.
Published in:
2011
By:
- Rajdev L;
- Negassa A;
- Dai Q;
- Goldberg G;
- Miller K;
- Sparano JA
Publication type:
Journal Article
Thiopurine methyltransferase polymorphisms and mercaptopurine tolerance in Turkish children with acute lymphoblastic leukemia.
Published in:
2011
By:
- Albayrak M;
- Konyssova U;
- Kaya Z;
- Gursel T;
- Guntekin S;
- Percin EF;
- Kocak U
Publication type:
Journal Article
Preclinical evaluation of the antitumor activity of bortezomib in combination with vitamin C or with epigallocatechin gallate, a component of green tea.
Published in:
2011
By:
- Bannerman B;
- Xu L;
- Jones M;
- Tsu C;
- Yu J;
- Hales P;
- Monbaliu J;
- Fleming P;
- Dick L;
- Manfredi M;
- Claiborne C;
- Bolen J;
- Kupperman E;
- Berger A;
- Bannerman, Bret;
- Xu, Ling;
- Jones, Matthew;
- Tsu, Christopher;
- Yu, Jie;
- Hales, Paul
Publication type:
journal article
First-line treatment of pancreatic cancer patients with the combination of 5-fluorouracil/folinic acid plus gemcitabine: a multicenter phase II trial by the CONKO-study group.
Published in:
2011
By:
- Pelzer U;
- Arnold D;
- Reitzig P;
- Herrenberger J;
- Korsten FW;
- Kindler M;
- Stieler J;
- Dörken B;
- Riess H;
- Oettle H
Publication type:
Journal Article
Severe fluoropyrimidine-related toxicity: clinical implications of DPYD analysis and UH2/U ratio evaluation.
Published in:
Cancer Chemotherapy & Pharmacology, 2011, v. 68, n. 5, p. 1355, doi. 10.1007/s00280-011-1709-6
By:
- Giorgio, E.;
- Caroti, C.;
- Mattioli, F.;
- Uliana, V.;
- Parodi, M.;
- D'Amico, Mauro;
- Fucile, C.;
- Marini, V.;
- Forzano, F.;
- Cassola, G.;
- Martelli, A.;
- Faravelli, F.;
- Di Maria, E.
Publication type:
Article
Thiopurine methyltransferase polymorphisms and mercaptopurine tolerance in Turkish children with acute lymphoblastic leukemia.
Published in:
Cancer Chemotherapy & Pharmacology, 2011, v. 68, n. 5, p. 1155, doi. 10.1007/s00280-011-1599-7
By:
- Albayrak, Meryem;
- Konyssova, Uljan;
- Kaya, Zuhre;
- Gursel, Turkiz;
- Guntekin, Sezen;
- Percin, E.;
- Kocak, Ulker
Publication type:
Article
First-line treatment of pancreatic cancer patients with the combination of 5-fluorouracil/folinic acid plus gemcitabine: a multicenter phase II trial by the CONKO-study group.
Published in:
Cancer Chemotherapy & Pharmacology, 2011, v. 68, n. 5, p. 1173, doi. 10.1007/s00280-011-1602-3
By:
- Pelzer, Uwe;
- Arnold, Dirk;
- Reitzig, Peter;
- Herrenberger, Julia;
- Korsten, Friedrich;
- Kindler, Manfred;
- Stieler, Jens;
- Dörken, Bernd;
- Riess, Hanno;
- Oettle, Helmut
Publication type:
Article
Interaction of sorafenib and cytochrome P450 isoenzymes in patients with advanced melanoma: a phase I/II pharmacokinetic interaction study.
Published in:
Cancer Chemotherapy & Pharmacology, 2011, v. 68, n. 5, p. 1111, doi. 10.1007/s00280-011-1585-0
By:
- Flaherty, Keith;
- Lathia, Chetan;
- Frye, Reginald;
- Schuchter, Lynn;
- Redlinger, Maryann;
- Rosen, Mark;
- O'Dwyer, Peter
Publication type:
Article
Aflibercept-mediated early angiogenic changes in aggressive B-cell lymphoma.
Published in:
Cancer Chemotherapy & Pharmacology, 2011, v. 68, n. 5, p. 1135, doi. 10.1007/s00280-011-1589-9
By:
- Romero, Martha;
- Brière, Josette;
- Bazelaire, Cédric;
- Lebœuf, Christophe;
- Wang, Li;
- Ratajczak, Philippe;
- Sibon, David;
- Kerviler, Eric;
- Thieblemont, Catherine;
- Janin, Anne
Publication type:
Article
Preclinical evaluation of the antitumor activity of bortezomib in combination with vitamin C or with epigallocatechin gallate, a component of green tea.
Published in:
Cancer Chemotherapy & Pharmacology, 2011, v. 68, n. 5, p. 1145, doi. 10.1007/s00280-011-1591-2
By:
- Bannerman, Bret;
- Xu, Ling;
- Jones, Matthew;
- Tsu, Christopher;
- Yu, Jie;
- Hales, Paul;
- Monbaliu, Johan;
- Fleming, Paul;
- Dick, Lawrence;
- Manfredi, Mark;
- Claiborne, Christopher;
- Bolen, Joseph;
- Kupperman, Erik;
- Berger, Allison
Publication type:
Article
Drug combinations with quercetin: doxorubicin plus quercetin in human breast cancer cells.
Published in:
Cancer Chemotherapy & Pharmacology, 2011, v. 68, n. 5, p. 1161, doi. 10.1007/s00280-011-1596-x
By:
- Staedler, Davide;
- Idrizi, Elita;
- Kenzaoui, Blanka;
- Juillerat-Jeanneret, Lucienne
Publication type:
Article
Phase I trial of metronomic oral vinorelbine in patients with advanced cancer.
Published in:
Cancer Chemotherapy & Pharmacology, 2011, v. 68, n. 5, p. 1119, doi. 10.1007/s00280-011-1580-5
By:
- Rajdev, Lakshmi;
- Negassa, Abdissa;
- Dai, Qun;
- Goldberg, Gary;
- Miller, Kathy;
- Sparano, Joseph
Publication type:
Article
The iron chelator Dp44mT inhibits the proliferation of cancer cells but fails to protect from doxorubicin-induced cardiotoxicity in spontaneously hypertensive rats.
Published in:
Cancer Chemotherapy & Pharmacology, 2011, v. 68, n. 5, p. 1125, doi. 10.1007/s00280-011-1587-y
By:
- Rao, V.;
- Zhang, Jun;
- Klein, Sarah;
- Espandiari, Parvaneh;
- Knapton, Alan;
- Dickey, Jennifer;
- Herman, Eugene;
- Shacter, Emily
Publication type:
Article
Accumulation and distribution of doxorubicin in tumour spheroids: the influence of acidity and expression of P-glycoprotein.
Published in:
Cancer Chemotherapy & Pharmacology, 2011, v. 68, n. 5, p. 1179, doi. 10.1007/s00280-011-1598-8
By:
- Mellor, Howard;
- Callaghan, Richard
Publication type:
Article
Population pharmacokinetics and pharmacogenetics of vincristine in paediatric patients treated for solid tumour diseases.
Published in:
Cancer Chemotherapy & Pharmacology, 2011, v. 68, n. 5, p. 1191, doi. 10.1007/s00280-010-1541-4
By:
- Guilhaumou, Romain;
- Simon, Nicolas;
- Quaranta, Sylvie;
- Verschuur, Arnauld;
- Lacarelle, Bruno;
- Andre, Nicolas;
- Solas, Caroline
Publication type:
Article
A multicenter, randomized, open-label study to assess the steady-state pharmacokinetics of bevacizumab given with either XELOX or FOLFOX-4 in patients with metastatic colorectal cancer.
Published in:
Cancer Chemotherapy & Pharmacology, 2011, v. 68, n. 5, p. 1199, doi. 10.1007/s00280-011-1606-z
By:
- Zhi, Jianguo;
- Chen, Eric;
- Major, Pierre;
- Burns, Ivon;
- Robinson, Bridget;
- McKendrick, Joe;
- Rittweger, Karen;
- Abt, Markus;
- Goldstein, David
Publication type:
Article
Bevacizumab-related arterial hypertension as a predictive marker in metastatic colorectal cancer patients.
Published in:
Cancer Chemotherapy & Pharmacology, 2011, v. 68, n. 5, p. 1207, doi. 10.1007/s00280-011-1604-1
By:
- De Stefano, Alfonso;
- Carlomagno, Chiara;
- Pepe, Stefano;
- Bianco, Roberto;
- De Placido, Sabino
Publication type:
Article
Phase II study of FOLFOX4 with 'wait and go' strategy as first-line treatment for metastatic colorectal cancer.
Published in:
Cancer Chemotherapy & Pharmacology, 2011, v. 68, n. 5, p. 1215, doi. 10.1007/s00280-011-1605-0
By:
- Kochi, Mitsugu;
- Ichikawa, Wataru;
- Meguro, Eiji;
- Shibata, Hiroyuki;
- Fukui, Takuji;
- Nagase, Michitaka;
- Hoshino, Yutaka;
- Takeuchi, Masahiro;
- Fujii, Masashi;
- Nakajima, Toshifusa
Publication type:
Article
Trabectedin has a low cardiac risk profile: a comprehensive cardiac safety analysis.
Published in:
Cancer Chemotherapy & Pharmacology, 2011, v. 68, n. 5, p. 1223, doi. 10.1007/s00280-011-1614-z
By:
- Lebedinsky, Claudia;
- Gómez, Javier;
- Park, Youn;
- Nieto, Antonio;
- Soto-Matos, Arturo;
- Parekh, Trilok;
- Alfaro, Vicente;
- Roy, Elena;
- Lardelli, Pilar;
- Kahatt, Carmen
Publication type:
Article
A phase I study of tasisulam sodium (LY573636 sodium), a novel anticancer compound in patients with refractory solid tumors.
Published in:
Cancer Chemotherapy & Pharmacology, 2011, v. 68, n. 5, p. 1233, doi. 10.1007/s00280-011-1593-0
By:
- Simon, George;
- Ilaria, Robert;
- Sovak, Mika;
- Williams, Charles;
- Haura, Eric;
- Cleverly, Ann;
- Sykes, Amanda;
- Wagner, Margaret;
- de Alwis, Dinesh;
- Slapak, Christopher;
- Miller, Mary;
- Spriggs, David
Publication type:
Article
A novel method for quantification of gemcitabine and its metabolites 2′,2′-difluorodeoxyuridine and gemcitabine triphosphate in tumour tissue by LC-MS/MS: comparison with F NMR spectroscopy.
Published in:
Cancer Chemotherapy & Pharmacology, 2011, v. 68, n. 5, p. 1243, doi. 10.1007/s00280-011-1613-0
By:
- Bapiro, Tashinga;
- Richards, Frances;
- Goldgraben, Mae;
- Olive, Kenneth;
- Madhu, Basetti;
- Frese, Kristopher;
- Cook, Natalie;
- Jacobetz, Michael;
- Smith, Donna-Michelle;
- Tuveson, David;
- Griffiths, John;
- Jodrell, Duncan
Publication type:
Article
Pharmacologic and phenotypic study of docetaxel in patients with ovarian or primary peritoneal cancer.
Published in:
Cancer Chemotherapy & Pharmacology, 2011, v. 68, n. 5, p. 1255, doi. 10.1007/s00280-011-1609-9
By:
- Zamboni, William;
- Combest, Austin;
- DeLoia, Julie;
- Edwards, Robert;
- Bridges, Arlene;
- Zamboni, Beth;
- Walko, Christine;
- Yu, Angela;
- Krivak, Thomas;
- Kelley, Joseph
Publication type:
Article
Single nucleotide polymorphisms of CYP19A1 predict clinical outcomes and adverse events associated with letrozole in patients with metastatic breast cancer.
Published in:
Cancer Chemotherapy & Pharmacology, 2011, v. 68, n. 5, p. 1263, doi. 10.1007/s00280-011-1615-y
By:
- Park, In;
- Lee, Yeon-Su;
- Lee, Keun;
- Kim, Sook-young;
- Hong, Seung-Hyun;
- Jeong, Jaeheon;
- Lee, Hyewon;
- Ro, Jungsil;
- Nam, Byung-Ho
Publication type:
Article
Role of 12-lipoxygenase in regulation of ovarian cancer cell proliferation and survival.
Published in:
Cancer Chemotherapy & Pharmacology, 2011, v. 68, n. 5, p. 1273, doi. 10.1007/s00280-011-1595-y
By:
- Guo, Austin;
- Liu, Xiuli;
- Al-Wahab, Zaid;
- Maddippati, Krishna;
- Ali-Fehmi, Rouba;
- Scicli, A.;
- Munkarah, Adnan
Publication type:
Article
Sorafenib for hepatocellular carcinoma according to Child-Pugh class of liver function.
Published in:
Cancer Chemotherapy & Pharmacology, 2011, v. 68, n. 5, p. 1285, doi. 10.1007/s00280-011-1616-x
By:
- Kim, Jeong;
- Ryoo, Baek-Yeol;
- Ryu, Min-Hee;
- Chang, Heung-Moon;
- Suh, Dong;
- Lee, Han;
- Lim, Young-Suk;
- Kim, Kang;
- Kang, Yoon-Koo
Publication type:
Article
Efficacy and pharmacokinetic/pharmacodynamic evaluation of the Aurora kinase A inhibitor MLN8237 against preclinical models of pediatric cancer.
Published in:
Cancer Chemotherapy & Pharmacology, 2011, v. 68, n. 5, p. 1291, doi. 10.1007/s00280-011-1618-8
By:
- Carol, Hernan;
- Boehm, Ingrid;
- Reynolds, C.;
- Kang, Min;
- Maris, John;
- Morton, Christopher;
- Gorlick, Richard;
- Kolb, E.;
- Keir, Stephen;
- Wu, Jianrong;
- Wozniak, Amy;
- Yang, Yu;
- Manfredi, Mark;
- Ecsedy, Jeffrey;
- Wang, Jianmin;
- Neale, Geoffrey;
- Houghton, Peter;
- Smith, Malcolm;
- Lock, Richard
Publication type:
Article
Pre-treatment lymphopenia as a prognostic biomarker in colorectal cancer patients receiving chemotherapy.
Published in:
Cancer Chemotherapy & Pharmacology, 2011, v. 68, n. 5, p. 1305, doi. 10.1007/s00280-011-1610-3
By:
- Cézé, N.;
- Thibault, G.;
- Goujon, G.;
- Viguier, J.;
- Watier, H.;
- Dorval, E.;
- Lecomte, T.
Publication type:
Article
Furanodienone induces cell cycle arrest and apoptosis by suppressing EGFR/HER2 signaling in HER2-overexpressing human breast cancer cells.
Published in:
Cancer Chemotherapy & Pharmacology, 2011, v. 68, n. 5, p. 1315, doi. 10.1007/s00280-011-1624-x
By:
- Li, Ying-Wei;
- Zhu, Guo-Yuan;
- Shen, Xiao-Ling;
- Chu, Jian-Hong;
- Yu, Zhi-Ling;
- Fong, Wang-Fun
Publication type:
Article
Amrubicin for the treatment of neuroendocrine carcinoma of the gastrointestinal tract: a retrospective analysis of five cases.
Published in:
Cancer Chemotherapy & Pharmacology, 2011, v. 68, n. 5, p. 1325, doi. 10.1007/s00280-011-1619-7
By:
- Asayama, Masako;
- Fuse, Nozomu;
- Yoshino, Takayuki;
- Yano, Tomonori;
- Tahara, Makoto;
- Doi, Toshihiko;
- Fujii, Satoshi;
- Ohtsu, Atsushi
Publication type:
Article
A phase 2 study of weekly albumin-bound paclitaxel (Abraxane) given as a two-hour infusion.
Published in:
Cancer Chemotherapy & Pharmacology, 2011, v. 68, n. 5, p. 1331, doi. 10.1007/s00280-011-1621-0
By:
- Paik, Paul;
- James, Leonard;
- Riely, Gregory;
- Azzoli, Christopher;
- Miller, Vincent;
- Ng, Kenneth;
- Sima, Camelia;
- Heelan, Robert;
- Kris, Mark;
- Moore, Erin;
- Rizvi, Naiyer
Publication type:
Article
Methotrexate toxicity and efficacy during the consolidation phase in paediatric acute lymphoblastic leukaemia and MTHFR polymorphisms as pharmacogenetic determinants.
Published in:
Cancer Chemotherapy & Pharmacology, 2011, v. 68, n. 5, p. 1339, doi. 10.1007/s00280-011-1665-1
By:
- D'Angelo, Velia;
- Ramaglia, Maria;
- Iannotta, Adriana;
- Crisci, Stefania;
- Indolfi, Paolo;
- Francese, Matteo;
- Affinita, Maria;
- Pecoraro, Giulia;
- Napolitano, Addolorata;
- Fusco, Claudia;
- Oreste, Matilde;
- Indolfi, Cristiana;
- Casale, Fiorina
Publication type:
Article
MTHFR 677TT genotype and toxicity of methotrexate: controversial results.
Published in:
2011
By:
- Lopez-Lopez, Elixabet;
- Ballesteros, Javier;
- Garcia-Orad, Africa
Publication type:
Letter
Reply.
Published in:
2011
By:
- D'Angelo, Velia
Publication type:
Letter
Pharmacokinetics of trabectedin on hemodialysis: an application for the management of cancer patients with end-stage renal disease.
Published in:
Cancer Chemotherapy & Pharmacology, 2011, v. 68, n. 5, p. 1363, doi. 10.1007/s00280-011-1718-5
By:
- Thariat, Juliette;
- Etienne-Grimaldi, Marie-Christine;
- Launay-Vacher, Vincent;
- Soto-Matos, Arturo;
- Fernandez-Teruel, Carlos;
- Ghafari, Thomas;
- Marcy, Pierre-Yves;
- Milano, Gérard;
- Renée, Nicole;
- Gastaud, Lauris;
- Thyss, Antoine
Publication type:
Article