Works in Cancer Chemotherapy & Pharmacology, 2011, Vol 68, Issue 5

Results: 52

A phase I-II study of elacytarabine (CP-4055) in the treatment of patients with ovarian cancer resistant or refractory to platinum therapy.

Published in:

2011

By:

Pignata S;
Amant F;
Scambia G;
Sorio R;
Breda E;
Rasch W;
Hernes K;
Pisano C;
Leunen K;
Lorusso D;
Cannella L;
Vergote I

Publication type:

Journal Article

Pre-treatment lymphopenia as a prognostic biomarker in colorectal cancer patients receiving chemotherapy.

Published in:

2011

By:

Cézé N;
Thibault G;
Goujon G;
Viguier J;
Watier H;
Dorval E;
Lecomte T

Publication type:

Journal Article

A phase 2 study of weekly albumin-bound paclitaxel (Abraxane®) given as a two-hour infusion.

Published in:

2011

By:

Paik PK;
James LP;
Riely GJ;
Azzoli CG;
Miller VA;
Ng KK;
Sima CS;
Heelan RT;
Kris MG;
Moore E;
Rizvi NA;
Paik, Paul K;
James, Leonard P;
Riely, Gregory J;
Azzoli, Christopher G;
Miller, Vincent A;
Ng, Kenneth K;
Sima, Camelia S;
Heelan, Robert T;
Kris, Mark G

Publication type:

journal article

Role of 12-lipoxygenase in regulation of ovarian cancer cell proliferation and survival.

Published in:

2011

By:

Guo AM;
Liu X;
Al-Wahab Z;
Maddippati KR;
Ali-Fehmi R;
Scicli AG;
Munkarah AR

Publication type:

Journal Article

MTHFR 677TT genotype and toxicity of methotrexate: controversial results.

Published in:

2011

By:

Lopez-Lopez E;
Ballesteros J;
Garcia-Orad A

Publication type:

Journal Article

Furanodienone induces cell cycle arrest and apoptosis by suppressing EGFR/HER2 signaling in HER2-overexpressing human breast cancer cells.

Published in:

2011

By:

Li YW;
Zhu GY;
Shen XL;
Chu JH;
Yu ZL;
Fong WF

Publication type:

Journal Article

Methotrexate toxicity and efficacy during the consolidation phase in paediatric acute lymphoblastic leukaemia and MTHFR polymorphisms as pharmacogenetic determinants.

Published in:

2011

By:

D'Angelo V;
Ramaglia M;
Iannotta A;
Crisci S;
Indolfi P;
Francese M;
Affinita MC;
Pecoraro G;
Napolitano A;
Fusco C;
Oreste M;
Indolfi C;
Casale F

Publication type:

Journal Article

Amrubicin for the treatment of neuroendocrine carcinoma of the gastrointestinal tract: a retrospective analysis of five cases.

Published in:

2011

By:

Asayama M;
Fuse N;
Yoshino T;
Yano T;
Tahara M;
Doi T;
Fujii S;
Ohtsu A

Publication type:

Journal Article

Pharmacologic and phenotypic study of docetaxel in patients with ovarian or primary peritoneal cancer.

Published in:

2011

By:

Zamboni WC;
Combest AJ;
Deloia JA;
Edwards RP;
Bridges AS;
Zamboni BA;
Walko CM;
Yu AY;
Krivak TC;
Kelley JL

Publication type:

Journal Article

A phase I study of tasisulam sodium (LY573636 sodium), a novel anticancer compound in patients with refractory solid tumors.

Published in:

2011

By:

Simon GR;
Ilaria RL Jr;
Sovak MA;
Williams CC;
Haura EB;
Cleverly AL;
Sykes AK;
Wagner MM;
de Alwis DP;
Slapak CA;
Miller MA;
Spriggs DR;
Simon, George R;
Ilaria, Robert L Jr;
Sovak, Mika A;
Williams, Charles C;
Haura, Eric B;
Cleverly, Ann L;
Sykes, Amanda K;
Wagner, Margaret M

Publication type:

journal article

A novel method for quantification of gemcitabine and its metabolites 2',2'-difluorodeoxyuridine and gemcitabine triphosphate in tumour tissue by LC-MS/MS: comparison with (19)F NMR spectroscopy.

Published in:

2011

By:

Bapiro TE;
Richards FM;
Goldgraben MA;
Olive KP;
Madhu B;
Frese KK;
Cook N;
Jacobetz MA;
Smith DM;
Tuveson DA;
Griffiths JR;
Jodrell DI;
Bapiro, Tashinga E;
Richards, Frances M;
Goldgraben, Mae A;
Olive, Kenneth P;
Madhu, Basetti;
Frese, Kristopher K;
Cook, Natalie;
Jacobetz, Michael A

Publication type:

journal article

Phase II study of FOLFOX4 with 'wait and go' strategy as first-line treatment for metastatic colorectal cancer.

Published in:

2011

By:

Kochi M;
Ichikawa W;
Meguro E;
Shibata H;
Fukui T;
Nagase M;
Hoshino Y;
Takeuchi M;
Fujii M;
Nakajima T

Publication type:

Journal Article

A multicenter, randomized, open-label study to assess the steady-state pharmacokinetics of bevacizumab given with either XELOX or FOLFOX-4 in patients with metastatic colorectal cancer.

Published in:

2011

By:

Zhi J;
Chen E;
Major P;
Burns I;
Robinson B;
McKendrick J;
Rittweger K;
Abt M;
Goldstein D

Publication type:

Journal Article

Bevacizumab-related arterial hypertension as a predictive marker in metastatic colorectal cancer patients.

Published in:

2011

By:

De Stefano A;
Carlomagno C;
Pepe S;
Bianco R;
De Placido S

Publication type:

Journal Article

Population pharmacokinetics and pharmacogenetics of vincristine in paediatric patients treated for solid tumour diseases.

Published in:

2011

By:

Guilhaumou R;
Simon N;
Quaranta S;
Verschuur A;
Lacarelle B;
Andre N;
Solas C

Publication type:

Journal Article

Interaction of sorafenib and cytochrome P450 isoenzymes in patients with advanced melanoma: a phase I/II pharmacokinetic interaction study.

Published in:

2011

By:

Flaherty KT;
Lathia C;
Frye RF;
Schuchter L;
Redlinger M;
Rosen M;
O'Dwyer PJ

Publication type:

Journal Article

Phase I trial of metronomic oral vinorelbine in patients with advanced cancer.

Published in:

2011

By:

Rajdev L;
Negassa A;
Dai Q;
Goldberg G;
Miller K;
Sparano JA

Publication type:

Journal Article

Severe fluoropyrimidine-related toxicity: clinical implications of DPYD analysis and UH2/U ratio evaluation.

Published in:

Cancer Chemotherapy & Pharmacology, 2011, v. 68, n. 5, p. 1355, doi. 10.1007/s00280-011-1709-6

By:

Giorgio, E.;
Caroti, C.;
Mattioli, F.;
Uliana, V.;
Parodi, M.;
D'Amico, Mauro;
Fucile, C.;
Marini, V.;
Forzano, F.;
Cassola, G.;
Martelli, A.;
Faravelli, F.;
Di Maria, E.

Publication type:

Article

Preclinical evaluation of the antitumor activity of bortezomib in combination with vitamin C or with epigallocatechin gallate, a component of green tea.

Published in:

2011

By:

Bannerman B;
Xu L;
Jones M;
Tsu C;
Yu J;
Hales P;
Monbaliu J;
Fleming P;
Dick L;
Manfredi M;
Claiborne C;
Bolen J;
Kupperman E;
Berger A;
Bannerman, Bret;
Xu, Ling;
Jones, Matthew;
Tsu, Christopher;
Yu, Jie;
Hales, Paul

Publication type:

journal article

Pharmacologic and phenotypic study of docetaxel in patients with ovarian or primary peritoneal cancer.

Published in:

Cancer Chemotherapy & Pharmacology, 2011, v. 68, n. 5, p. 1255, doi. 10.1007/s00280-011-1609-9

By:

Zamboni, William;
Combest, Austin;
DeLoia, Julie;
Edwards, Robert;
Bridges, Arlene;
Zamboni, Beth;
Walko, Christine;
Yu, Angela;
Krivak, Thomas;
Kelley, Joseph

Publication type:

Article

Thiopurine methyltransferase polymorphisms and mercaptopurine tolerance in Turkish children with acute lymphoblastic leukemia.

Published in:

2011

By:

Albayrak M;
Konyssova U;
Kaya Z;
Gursel T;
Guntekin S;
Percin EF;
Kocak U

Publication type:

Journal Article

First-line treatment of pancreatic cancer patients with the combination of 5-fluorouracil/folinic acid plus gemcitabine: a multicenter phase II trial by the CONKO-study group.

Published in:

2011

By:

Pelzer U;
Arnold D;
Reitzig P;
Herrenberger J;
Korsten FW;
Kindler M;
Stieler J;
Dörken B;
Riess H;
Oettle H

Publication type:

Journal Article

Single nucleotide polymorphisms of CYP19A1 predict clinical outcomes and adverse events associated with letrozole in patients with metastatic breast cancer.

Published in:

Cancer Chemotherapy & Pharmacology, 2011, v. 68, n. 5, p. 1263, doi. 10.1007/s00280-011-1615-y

By:

Park, In;
Lee, Yeon-Su;
Lee, Keun;
Kim, Sook-young;
Hong, Seung-Hyun;
Jeong, Jaeheon;
Lee, Hyewon;
Ro, Jungsil;
Nam, Byung-Ho

Publication type:

Article

Interaction of sorafenib and cytochrome P450 isoenzymes in patients with advanced melanoma: a phase I/II pharmacokinetic interaction study.

Published in:

Cancer Chemotherapy & Pharmacology, 2011, v. 68, n. 5, p. 1111, doi. 10.1007/s00280-011-1585-0

By:

Flaherty, Keith;
Lathia, Chetan;
Frye, Reginald;
Schuchter, Lynn;
Redlinger, Maryann;
Rosen, Mark;
O'Dwyer, Peter

Publication type:

Article

Role of 12-lipoxygenase in regulation of ovarian cancer cell proliferation and survival.

Published in:

Cancer Chemotherapy & Pharmacology, 2011, v. 68, n. 5, p. 1273, doi. 10.1007/s00280-011-1595-y

By:

Guo, Austin;
Liu, Xiuli;
Al-Wahab, Zaid;
Maddippati, Krishna;
Ali-Fehmi, Rouba;
Scicli, A.;
Munkarah, Adnan

Publication type:

Article

Sorafenib for hepatocellular carcinoma according to Child-Pugh class of liver function.

Published in:

Cancer Chemotherapy & Pharmacology, 2011, v. 68, n. 5, p. 1285, doi. 10.1007/s00280-011-1616-x

By:

Kim, Jeong;
Ryoo, Baek-Yeol;
Ryu, Min-Hee;
Chang, Heung-Moon;
Suh, Dong;
Lee, Han;
Lim, Young-Suk;
Kim, Kang;
Kang, Yoon-Koo

Publication type:

Article

Efficacy and pharmacokinetic/pharmacodynamic evaluation of the Aurora kinase A inhibitor MLN8237 against preclinical models of pediatric cancer.

Published in:

Cancer Chemotherapy & Pharmacology, 2011, v. 68, n. 5, p. 1291, doi. 10.1007/s00280-011-1618-8

By:

Carol, Hernan;
Boehm, Ingrid;
Reynolds, C.;
Kang, Min;
Maris, John;
Morton, Christopher;
Gorlick, Richard;
Kolb, E.;
Keir, Stephen;
Wu, Jianrong;
Wozniak, Amy;
Yang, Yu;
Manfredi, Mark;
Ecsedy, Jeffrey;
Wang, Jianmin;
Neale, Geoffrey;
Houghton, Peter;
Smith, Malcolm;
Lock, Richard

Publication type:

Article

Phase I trial of metronomic oral vinorelbine in patients with advanced cancer.

Published in:

Cancer Chemotherapy & Pharmacology, 2011, v. 68, n. 5, p. 1119, doi. 10.1007/s00280-011-1580-5

By:

Rajdev, Lakshmi;
Negassa, Abdissa;
Dai, Qun;
Goldberg, Gary;
Miller, Kathy;
Sparano, Joseph

Publication type:

Article

The iron chelator Dp44mT inhibits the proliferation of cancer cells but fails to protect from doxorubicin-induced cardiotoxicity in spontaneously hypertensive rats.

Published in:

Cancer Chemotherapy & Pharmacology, 2011, v. 68, n. 5, p. 1125, doi. 10.1007/s00280-011-1587-y

By:

Rao, V.;
Zhang, Jun;
Klein, Sarah;
Espandiari, Parvaneh;
Knapton, Alan;
Dickey, Jennifer;
Herman, Eugene;
Shacter, Emily

Publication type:

Article

Aflibercept-mediated early angiogenic changes in aggressive B-cell lymphoma.

Published in:

Cancer Chemotherapy & Pharmacology, 2011, v. 68, n. 5, p. 1135, doi. 10.1007/s00280-011-1589-9

By:

Romero, Martha;
Brière, Josette;
Bazelaire, Cédric;
Lebœuf, Christophe;
Wang, Li;
Ratajczak, Philippe;
Sibon, David;
Kerviler, Eric;
Thieblemont, Catherine;
Janin, Anne

Publication type:

Article

Preclinical evaluation of the antitumor activity of bortezomib in combination with vitamin C or with epigallocatechin gallate, a component of green tea.

Published in:

Cancer Chemotherapy & Pharmacology, 2011, v. 68, n. 5, p. 1145, doi. 10.1007/s00280-011-1591-2

By:

Bannerman, Bret;
Xu, Ling;
Jones, Matthew;
Tsu, Christopher;
Yu, Jie;
Hales, Paul;
Monbaliu, Johan;
Fleming, Paul;
Dick, Lawrence;
Manfredi, Mark;
Claiborne, Christopher;
Bolen, Joseph;
Kupperman, Erik;
Berger, Allison

Publication type:

Article

Thiopurine methyltransferase polymorphisms and mercaptopurine tolerance in Turkish children with acute lymphoblastic leukemia.

Published in:

Cancer Chemotherapy & Pharmacology, 2011, v. 68, n. 5, p. 1155, doi. 10.1007/s00280-011-1599-7

By:

Albayrak, Meryem;
Konyssova, Uljan;
Kaya, Zuhre;
Gursel, Turkiz;
Guntekin, Sezen;
Percin, E.;
Kocak, Ulker

Publication type:

Article

Drug combinations with quercetin: doxorubicin plus quercetin in human breast cancer cells.

Published in:

Cancer Chemotherapy & Pharmacology, 2011, v. 68, n. 5, p. 1161, doi. 10.1007/s00280-011-1596-x

By:

Staedler, Davide;
Idrizi, Elita;
Kenzaoui, Blanka;
Juillerat-Jeanneret, Lucienne

Publication type:

Article

First-line treatment of pancreatic cancer patients with the combination of 5-fluorouracil/folinic acid plus gemcitabine: a multicenter phase II trial by the CONKO-study group.

Published in:

Cancer Chemotherapy & Pharmacology, 2011, v. 68, n. 5, p. 1173, doi. 10.1007/s00280-011-1602-3

By:

Pelzer, Uwe;
Arnold, Dirk;
Reitzig, Peter;
Herrenberger, Julia;
Korsten, Friedrich;
Kindler, Manfred;
Stieler, Jens;
Dörken, Bernd;
Riess, Hanno;
Oettle, Helmut

Publication type:

Article

Accumulation and distribution of doxorubicin in tumour spheroids: the influence of acidity and expression of P-glycoprotein.

Published in:

Cancer Chemotherapy & Pharmacology, 2011, v. 68, n. 5, p. 1179, doi. 10.1007/s00280-011-1598-8

By:

Mellor, Howard;
Callaghan, Richard

Publication type:

Article

Population pharmacokinetics and pharmacogenetics of vincristine in paediatric patients treated for solid tumour diseases.

Published in:

Cancer Chemotherapy & Pharmacology, 2011, v. 68, n. 5, p. 1191, doi. 10.1007/s00280-010-1541-4

By:

Guilhaumou, Romain;
Simon, Nicolas;
Quaranta, Sylvie;
Verschuur, Arnauld;
Lacarelle, Bruno;
Andre, Nicolas;
Solas, Caroline

Publication type:

Article

A multicenter, randomized, open-label study to assess the steady-state pharmacokinetics of bevacizumab given with either XELOX or FOLFOX-4 in patients with metastatic colorectal cancer.

Published in:

Cancer Chemotherapy & Pharmacology, 2011, v. 68, n. 5, p. 1199, doi. 10.1007/s00280-011-1606-z

By:

Zhi, Jianguo;
Chen, Eric;
Major, Pierre;
Burns, Ivon;
Robinson, Bridget;
McKendrick, Joe;
Rittweger, Karen;
Abt, Markus;
Goldstein, David

Publication type:

Article

Bevacizumab-related arterial hypertension as a predictive marker in metastatic colorectal cancer patients.

Published in:

Cancer Chemotherapy & Pharmacology, 2011, v. 68, n. 5, p. 1207, doi. 10.1007/s00280-011-1604-1

By:

De Stefano, Alfonso;
Carlomagno, Chiara;
Pepe, Stefano;
Bianco, Roberto;
De Placido, Sabino

Publication type:

Article

Phase II study of FOLFOX4 with 'wait and go' strategy as first-line treatment for metastatic colorectal cancer.

Published in:

Cancer Chemotherapy & Pharmacology, 2011, v. 68, n. 5, p. 1215, doi. 10.1007/s00280-011-1605-0

By:

Kochi, Mitsugu;
Ichikawa, Wataru;
Meguro, Eiji;
Shibata, Hiroyuki;
Fukui, Takuji;
Nagase, Michitaka;
Hoshino, Yutaka;
Takeuchi, Masahiro;
Fujii, Masashi;
Nakajima, Toshifusa

Publication type:

Article

Trabectedin has a low cardiac risk profile: a comprehensive cardiac safety analysis.

Published in:

Cancer Chemotherapy & Pharmacology, 2011, v. 68, n. 5, p. 1223, doi. 10.1007/s00280-011-1614-z

By:

Lebedinsky, Claudia;
Gómez, Javier;
Park, Youn;
Nieto, Antonio;
Soto-Matos, Arturo;
Parekh, Trilok;
Alfaro, Vicente;
Roy, Elena;
Lardelli, Pilar;
Kahatt, Carmen

Publication type:

Article

A phase I study of tasisulam sodium (LY573636 sodium), a novel anticancer compound in patients with refractory solid tumors.

Published in:

Cancer Chemotherapy & Pharmacology, 2011, v. 68, n. 5, p. 1233, doi. 10.1007/s00280-011-1593-0

By:

Simon, George;
Ilaria, Robert;
Sovak, Mika;
Williams, Charles;
Haura, Eric;
Cleverly, Ann;
Sykes, Amanda;
Wagner, Margaret;
de Alwis, Dinesh;
Slapak, Christopher;
Miller, Mary;
Spriggs, David

Publication type:

Article

A novel method for quantification of gemcitabine and its metabolites 2′,2′-difluorodeoxyuridine and gemcitabine triphosphate in tumour tissue by LC-MS/MS: comparison with F NMR spectroscopy.

Published in:

Cancer Chemotherapy & Pharmacology, 2011, v. 68, n. 5, p. 1243, doi. 10.1007/s00280-011-1613-0

By:

Bapiro, Tashinga;
Richards, Frances;
Goldgraben, Mae;
Olive, Kenneth;
Madhu, Basetti;
Frese, Kristopher;
Cook, Natalie;
Jacobetz, Michael;
Smith, Donna-Michelle;
Tuveson, David;
Griffiths, John;
Jodrell, Duncan

Publication type:

Article

Pre-treatment lymphopenia as a prognostic biomarker in colorectal cancer patients receiving chemotherapy.

Published in:

Cancer Chemotherapy & Pharmacology, 2011, v. 68, n. 5, p. 1305, doi. 10.1007/s00280-011-1610-3

By:

Cézé, N.;
Thibault, G.;
Goujon, G.;
Viguier, J.;
Watier, H.;
Dorval, E.;
Lecomte, T.

Publication type:

Article

Furanodienone induces cell cycle arrest and apoptosis by suppressing EGFR/HER2 signaling in HER2-overexpressing human breast cancer cells.

Published in:

Cancer Chemotherapy & Pharmacology, 2011, v. 68, n. 5, p. 1315, doi. 10.1007/s00280-011-1624-x

By:

Li, Ying-Wei;
Zhu, Guo-Yuan;
Shen, Xiao-Ling;
Chu, Jian-Hong;
Yu, Zhi-Ling;
Fong, Wang-Fun

Publication type:

Article

Amrubicin for the treatment of neuroendocrine carcinoma of the gastrointestinal tract: a retrospective analysis of five cases.

Published in:

Cancer Chemotherapy & Pharmacology, 2011, v. 68, n. 5, p. 1325, doi. 10.1007/s00280-011-1619-7

By:

Asayama, Masako;
Fuse, Nozomu;
Yoshino, Takayuki;
Yano, Tomonori;
Tahara, Makoto;
Doi, Toshihiko;
Fujii, Satoshi;
Ohtsu, Atsushi

Publication type:

Article

A phase 2 study of weekly albumin-bound paclitaxel (Abraxane) given as a two-hour infusion.

Published in:

Cancer Chemotherapy & Pharmacology, 2011, v. 68, n. 5, p. 1331, doi. 10.1007/s00280-011-1621-0

By:

Paik, Paul;
James, Leonard;
Riely, Gregory;
Azzoli, Christopher;
Miller, Vincent;
Ng, Kenneth;
Sima, Camelia;
Heelan, Robert;
Kris, Mark;
Moore, Erin;
Rizvi, Naiyer

Publication type:

Article

Methotrexate toxicity and efficacy during the consolidation phase in paediatric acute lymphoblastic leukaemia and MTHFR polymorphisms as pharmacogenetic determinants.

Published in:

Cancer Chemotherapy & Pharmacology, 2011, v. 68, n. 5, p. 1339, doi. 10.1007/s00280-011-1665-1

By:

D'Angelo, Velia;
Ramaglia, Maria;
Iannotta, Adriana;
Crisci, Stefania;
Indolfi, Paolo;
Francese, Matteo;
Affinita, Maria;
Pecoraro, Giulia;
Napolitano, Addolorata;
Fusco, Claudia;
Oreste, Matilde;
Indolfi, Cristiana;
Casale, Fiorina

Publication type:

Article

MTHFR 677TT genotype and toxicity of methotrexate: controversial results.

Published in:

2011

By:

Lopez-Lopez, Elixabet;
Ballesteros, Javier;
Garcia-Orad, Africa

Publication type:

Letter

Reply.

Published in:

2011

By:

D'Angelo, Velia

Publication type:

Letter

Pharmacokinetics of trabectedin on hemodialysis: an application for the management of cancer patients with end-stage renal disease.

Published in:

Cancer Chemotherapy & Pharmacology, 2011, v. 68, n. 5, p. 1363, doi. 10.1007/s00280-011-1718-5

By:

Thariat, Juliette;
Etienne-Grimaldi, Marie-Christine;
Launay-Vacher, Vincent;
Soto-Matos, Arturo;
Fernandez-Teruel, Carlos;
Ghafari, Thomas;
Marcy, Pierre-Yves;
Milano, Gérard;
Renée, Nicole;
Gastaud, Lauris;
Thyss, Antoine

Publication type:

Article