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Results: 24

First report of X-ray induced somatic mutation by Muller's department chair fails to support Muller's linearity hypothesis.
Published in:
Archives of Toxicology, 2024, v. 98, n. 8, p. 2731, doi. 10.1007/s00204-024-03808-0
By:
- Calabrese, Edward;
- Selby, Paul B.
Publication type:
Article
Newly discovered letter: why Muller failed to cite the negative mouse mutation findings of Snell, preserving his chances to receive the Nobel Prize.
Published in:
Archives of Toxicology, 2024, v. 98, n. 8, p. 2739, doi. 10.1007/s00204-024-03807-1
By:
- Calabrese, Edward J.;
- Selby, Paul B.
Publication type:
Article
Time for CHANGE: system-level interventions for bringing forward the date of effective use of NAMs in regulatory toxicology.
Published in:
Archives of Toxicology, 2024, v. 98, n. 8, p. 2299, doi. 10.1007/s00204-024-03802-6
By:
- Mathisen, Gro H.;
- Bearth, Angela;
- Jones, Lowenna B.;
- Hoffmann, Sebastian;
- Vist, Gunn E.;
- Ames, Heather M.;
- Husøy, Trine;
- Svendsen, Camilla;
- Tsaioun, Katya;
- Ashikaga, Takao;
- Bloch, Denise;
- Cavoski, Aleksandra;
- Chiu, Weihsueh A.;
- Davies, Holly G.;
- Giusti, Arianna;
- Hartung, Thomas;
- Hirabayashi, Yoko;
- Hogberg, Helena T.;
- Joglekar, Rashmi;
- Kojima, Hajime
Publication type:
Article
Bisphenol A and its analogues: from their occurrence in foodstuffs marketed in Europe to improved monitoring strategies—a review of published literature from 2018 to 2023.
Published in:
Archives of Toxicology, 2024, v. 98, n. 8, p. 2441, doi. 10.1007/s00204-024-03793-4
By:
- Neri, Ilaria;
- Russo, Giacomo;
- Grumetto, Lucia
Publication type:
Article
The Emerging Role of Natural Products in Cancer Treatment.
Published in:
Archives of Toxicology, 2024, v. 98, n. 8, p. 2353, doi. 10.1007/s00204-024-03786-3
By:
- Ghosh, Sumit;
- Das, Sanjib Kumar;
- Sinha, Krishnendu;
- Ghosh, Biswatosh;
- Sen, Koushik;
- Ghosh, Nabanita;
- Sil, Parames C.
Publication type:
Article
Applications of 3D organoids in toxicological studies: a comprehensive analysis based on bibliometrics and advances in toxicological mechanisms.
Published in:
Archives of Toxicology, 2024, v. 98, n. 8, p. 2309, doi. 10.1007/s00204-024-03777-4
By:
- Yang, Haitao;
- Niu, Shuyan;
- Guo, Menghao;
- Xue, Yuying
Publication type:
Article
Mechanistic safety assessment via multi-omic characterisation of systemic pathway perturbations following in vivo MAT2A inhibition.
Published in:
Archives of Toxicology, 2024, v. 98, n. 8, p. 2589, doi. 10.1007/s00204-024-03771-w
By:
- Fogal, Valentina;
- Michopoulos, Filippos;
- Jarnuczak, Andrew F.;
- Hamza, Ghaith M.;
- Harlfinger, Stephanie;
- Davey, Paul;
- Hulme, Heather;
- Atkinson, Stephen J.;
- Gabrowski, Piotr;
- Cheung, Tony;
- Grondine, Michael;
- Hoover, Clare;
- Rose, Jonathan;
- Bray, Chandler;
- Foster, Alison J.;
- Askin, Sean;
- Majumder, Muntasir Mamun;
- Fitzpatrick, Paul;
- Miele, Eric;
- Macdonald, Ruth
Publication type:
Article
Targeting gut microbiota for immunotherapy of diseases.
Published in:
Archives of Toxicology, 2024, v. 98, n. 8, p. 2429, doi. 10.1007/s00204-024-03770-x
By:
- Yu, Ya-Jie;
- Liu, Xiao-Dong;
- Liao, Cai;
- Yu, Rui;
- Wang, Xin;
- Li, Ming;
- Wang, Yun
Publication type:
Article
Investigation of the intrinsic cannabinoid activity of hemp-derived and semisynthetic cannabinoids with β-arrestin2 recruitment assays—and how this matters for the harm potential of seized drugs.
Published in:
Archives of Toxicology, 2024, v. 98, n. 8, p. 2619, doi. 10.1007/s00204-024-03769-4
By:
- Janssens, Liesl K.;
- Van Uytfanghe, Katleen;
- Williams, Jeffrey B.;
- Hering, Kirk W.;
- Iula, Donna M.;
- Stove, Christophe P.
Publication type:
Article
The role of cellular senescence in neurodegenerative diseases.
Published in:
Archives of Toxicology, 2024, v. 98, n. 8, p. 2393, doi. 10.1007/s00204-024-03768-5
By:
- Wang, Yating;
- Kuca, Kamil;
- You, Li;
- Nepovimova, Eugenie;
- Heger, Zbynek;
- Valko, Marian;
- Adam, Vojtech;
- Wu, Qinghua;
- Jomova, Klaudia
Publication type:
Article
Mechanistic screening of reproductive toxicity in a novel 3D testicular co-culture model shows significant impairments following exposure to low-dibutyl phthalate concentrations.
Published in:
Archives of Toxicology, 2024, v. 98, n. 8, p. 2695, doi. 10.1007/s00204-024-03767-6
By:
- Almamoun, Radwa;
- Pierozan, Paula;
- Karlsson, Oskar
Publication type:
Article
In vitro assessment of thyroid peroxidase inhibition by chemical exposure: comparison of cell models and detection methods.
Published in:
Archives of Toxicology, 2024, v. 98, n. 8, p. 2631, doi. 10.1007/s00204-024-03766-7
By:
- Liu, Runze;
- Novák, Jiří;
- Hilscherová, Klára
Publication type:
Article
The entactogen 3,4-methylenedioxymethamphetamine (MDMA; ecstasy) as a treatment aid in psychotherapy and its safety concerns.
Published in:
Archives of Toxicology, 2024, v. 98, n. 8, p. 2409, doi. 10.1007/s00204-024-03765-8
By:
- Baldo, Brian A.
Publication type:
Article
Systematic evaluation of high-throughput PBK modelling strategies for the prediction of intravenous and oral pharmacokinetics in humans.
Published in:
Archives of Toxicology, 2024, v. 98, n. 8, p. 2659, doi. 10.1007/s00204-024-03764-9
By:
- Geci, René;
- Gadaleta, Domenico;
- de Lomana, Marina García;
- Ortega-Vallbona, Rita;
- Colombo, Erika;
- Serrano-Candelas, Eva;
- Paini, Alicia;
- Kuepfer, Lars;
- Schaller, Stephan
Publication type:
Article
Lack of CYP3A4 protein induction despite mRNA induction in primary hepatocytes exposed to rifabutin as a possible explanation for its low interaction risk in vivo.
Published in:
Archives of Toxicology, 2024, v. 98, n. 8, p. 2541, doi. 10.1007/s00204-024-03763-w
By:
- Nilles, Julie;
- Theile, Dirk;
- Weiss, Johanna;
- Haefeli, Walter E.;
- Ruez, Stephanie
Publication type:
Article
Functional metabolomics characterizes the contribution of farnesoid X receptor in pyrrolizidine alkaloid-induced hepatic sinusoidal obstruction syndrome.
Published in:
Archives of Toxicology, 2024, v. 98, n. 8, p. 2557, doi. 10.1007/s00204-024-03762-x
By:
- Xiong, Aizhen;
- Lu, Longhui;
- Jiang, Kaiyuan;
- Wang, Xiaoning;
- Chen, Yan;
- Wang, Xunjiang;
- Zhang, Wei;
- Zhuge, Yuzheng;
- Huang, Wendong;
- Li, Lujin;
- Liao, Qi;
- Yang, Fan;
- Liu, Ping;
- Ding, Lili;
- Wang, Zhengtao;
- Yang, Li
Publication type:
Article
Metabolism of alcohol ethoxylates (AEs) in rat, hamster, and human hepatocytes and liver S9: a pilot study for metabolic stability, metabolic pathway, and metabolites identification in vitro and in silico.
Published in:
Archives of Toxicology, 2024, v. 98, n. 8, p. 2487, doi. 10.1007/s00204-024-03761-y
By:
- Shi, Quan;
- Moors, Stefan;
- Dawick, James;
- Kavanagh, Lauren;
- Neely, Theresa;
- Tian, Yuan;
- Dreeßen, Birte;
- Carrillo, Juan-Carlos;
- Hein, Holger;
- Boogaard, Peter J.
Publication type:
Article
Multi-omics bioactivity profile-based chemical grouping and read-across: a case study with Daphnia magna and azo dyes.
Published in:
Archives of Toxicology, 2024, v. 98, n. 8, p. 2577, doi. 10.1007/s00204-024-03759-6
By:
- Gruszczynska, Hanna;
- Barnett, Rosemary E.;
- Lloyd, Gavin R.;
- Weber, Ralf J. M.;
- Lawson, Thomas N.;
- Zhou, Jiarui;
- Sostare, Elena;
- Colbourne, John K.;
- Viant, Mark R.
Publication type:
Article
Defining the mechanisms behind the hepatoprotective properties of curcumin.
Published in:
Archives of Toxicology, 2024, v. 98, n. 8, p. 2331, doi. 10.1007/s00204-024-03758-7
By:
- Yashmi, Farinam;
- Fakhri, Sajad;
- Shiri Varnamkhasti, Behrang;
- Amin, Mohammed Namiq;
- Khirehgesh, Mohammad Reza;
- Mohammadi-Noori, Ehsan;
- Hosseini, Mahsa;
- Khan, Haroon
Publication type:
Article
Formation of functional, extended bile canaliculi, and increased bile acid production in sandwich-cultured human cryopreserved hepatocytes using commercially available culture medium.
Published in:
Archives of Toxicology, 2024, v. 98, n. 8, p. 2605, doi. 10.1007/s00204-024-03757-8
By:
- Horiuchi, Shinichiro;
- Kuroda, Yukie;
- Oyafuso, Ryota;
- Komizu, Yuji;
- Maeda, Kazuya;
- Ishida, Seiichi
Publication type:
Article
Harnessing machine learning to predict cytochrome P450 inhibition through molecular properties.
Published in:
Archives of Toxicology, 2024, v. 98, n. 8, p. 2647, doi. 10.1007/s00204-024-03756-9
By:
- Zahid, Hamza;
- Tayara, Hilal;
- Chong, Kil To
Publication type:
Article
A novel support vector machine-based 1-day, single-dose prediction model of genotoxic hepatocarcinogenicity in rats.
Published in:
Archives of Toxicology, 2024, v. 98, n. 8, p. 2711, doi. 10.1007/s00204-024-03755-w
By:
- Gi, Min;
- Suzuki, Shugo;
- Kanki, Masayuki;
- Yokohira, Masanao;
- Tsukamoto, Tetsuya;
- Fujioka, Masaki;
- Vachiraarunwong, Arpamas;
- Qiu, Guiyu;
- Guo, Runjie;
- Wanibuchi, Hideki
Publication type:
Article
Toxicity of cannabidiol and its metabolites in TM3 mouse Leydig cells: a comparison with primary human Leydig cells.
Published in:
Archives of Toxicology, 2024, v. 98, n. 8, p. 2677, doi. 10.1007/s00204-024-03754-x
By:
- Li, Yuxi;
- Wu, Qiangen;
- Li, Xilin;
- Cournoyer, Patrick;
- Choudhuri, Supratim;
- Guo, Lei;
- Chen, Si
Publication type:
Article
A modular strategy for the testing and assessment of non-genotoxic carcinogens.
Published in:
Archives of Toxicology, 2024, v. 98, n. 8, p. 2463, doi. 10.1007/s00204-024-03753-y
By:
- Louekari, Kimmo;
- Jacobs, Miriam N.
Publication type:
Article