Works matching IS 03405761 AND DT 2023 AND VI 97 AND IP 5

Results: 15

Potency ranking of pyrrolizidine alkaloids in metabolically competent human liver cancer cells and primary human hepatocytes using a genotoxicity test battery.

Published in:

Archives of Toxicology, 2023, v. 97, n. 5, p. 1413, doi. 10.1007/s00204-023-03482-8

By:

Haas, Manuel;
Wirachowski, Karina;
Thibol, Lea;
Küpper, Jan-Heiner;
Schrenk, Dieter;
Fahrer, Jörg

Publication type:

Article

Modernizing persistence–bioaccumulation–toxicity (PBT) assessment with high throughput animal-free methods.

Published in:

Archives of Toxicology, 2023, v. 97, n. 5, p. 1267, doi. 10.1007/s00204-023-03485-5

By:

Escher, Beate I.;
Altenburger, Rolf;
Blüher, Matthias;
Colbourne, John K.;
Ebinghaus, Ralf;
Fantke, Peter;
Hein, Michaela;
Köck, Wolfgang;
Kümmerer, Klaus;
Leipold, Sina;
Li, Xiaojing;
Scheringer, Martin;
Scholz, Stefan;
Schloter, Michael;
Schweizer, Pia-Johanna;
Tal, Tamara;
Tetko, Igor;
Traidl-Hoffmann, Claudia;
Wick, Lukas Y.;
Fenner, Kathrin

Publication type:

Article

The role of hypoxia-inducible factor 1 alpha (HIF-1α) modulation in heavy metal toxicity.

Published in:

Archives of Toxicology, 2023, v. 97, n. 5, p. 1299, doi. 10.1007/s00204-023-03483-7

By:

Aschner, Michael;
Skalny, Anatoly V.;
Lu, Rongzhu;
Santamaria, Abel;
Zhou, Ji-Chang;
Ke, Tao;
Karganov, Mikhail Yu.;
Tsatsakis, Aristides;
Golokhvast, Kirill S.;
Bowman, Aaron B.;
Tinkov, Alexey A.

Publication type:

Article

ECHA ARN documents: chemical grouping without a toxicological rationale.

Published in:

Archives of Toxicology, 2023, v. 97, n. 5, p. 1433, doi. 10.1007/s00204-023-03479-3

By:

Natsch, Andreas;
Adamsson, Greg;
Rocha, Vanessa

Publication type:

Article

Dose-dependent pleiotropic role of neutrophils during acetaminophen-induced liver injury in male and female mice.

Published in:

Archives of Toxicology, 2023, v. 97, n. 5, p. 1397, doi. 10.1007/s00204-023-03478-4

By:

Nguyen, Nga T.;
Umbaugh, David S.;
Smith, Sawyer;
Adelusi, Olamide B.;
Sanchez-Guerrero, Giselle;
Ramachandran, Anup;
Jaeschke, Hartmut

Publication type:

Article

A review of cardiovascular effects and underlying mechanisms of legacy and emerging per- and polyfluoroalkyl substances (PFAS).

Published in:

Archives of Toxicology, 2023, v. 97, n. 5, p. 1195, doi. 10.1007/s00204-023-03477-5

By:

Wen, Zeng-Jin;
Wei, Yi-Jing;
Zhang, Yi-Fei;
Zhang, Yin-Feng

Publication type:

Article

Hexahydro-1,3,5-trinitro-1,3,5-triazine (RDX) causes seizure activity in larval zebrafish via antagonism of γ-aminobutyric acid type A receptor α1β2γ2.

Published in:

Archives of Toxicology, 2023, v. 97, n. 5, p. 1355, doi. 10.1007/s00204-023-03475-7

By:

Mundy, Paige C.;
Werner, Alicia;
Singh, Latika;
Singh, Vikrant;
Mendieta, Rosalia;
Patullo, Caitlyn E.;
Wulff, Heike;
Lein, Pamela J.

Publication type:

Article

In memoriam Thomas Gebel.

Published in:

Archives of Toxicology, 2023, v. 97, n. 5, p. 1193, doi. 10.1007/s00204-023-03473-9

By:

Hengstler, Jan G.;
Bolt, Hermann;
Heinrich, Uwe;
Hartwig, Andrea;
Landsiedel, Robert

Publication type:

Article

Metabolic signature of HepaRG cells exposed to ethanol and tumor necrosis factor alpha to study alcoholic steatohepatitis by LC–MS-based untargeted metabolomics.

Published in:

Archives of Toxicology, 2023, v. 97, n. 5, p. 1335, doi. 10.1007/s00204-023-03470-y

By:

Iturrospe, Elias;
Robeyns, Rani;
da Silva, Katyeny Manuela;
van de Lavoir, Maria;
Boeckmans, Joost;
Vanhaecke, Tamara;
van Nuijs, Alexander L. N.;
Covaci, Adrian

Publication type:

Article

Lysosomal dysfunction in Schwann cells is involved in bortezomib-induced peripheral neurotoxicity.

Published in:

Archives of Toxicology, 2023, v. 97, n. 5, p. 1385, doi. 10.1007/s00204-023-03468-6

By:

Wu, Zhanxun;
Yan, Wenping;
Wang, Ke;
Xu, Genghua;
Zhu, Danyan;
Li, Xuyun;
Wang, Huafeng;
Yang, Min;
Zhang, Xiangnan;
Wu, Jiaying

Publication type:

Article

Toxicology of 3-monochloropropane-1,2-diol and its esters: a narrative review.

Published in:

Archives of Toxicology, 2023, v. 97, n. 5, p. 1247, doi. 10.1007/s00204-023-03467-7

By:

Fattore, Elena;
Lanno, Alessia;
Danieli, Alberto;
Stefano, Simone;
Passoni, Alice;
Roncaglioni, Alessandra;
Bagnati, Renzo;
Davoli, Enrico

Publication type:

Article

Organoid-based 3D in vitro microphysiological systems as alternatives to animal experimentation for preclinical and clinical research.

Published in:

Archives of Toxicology, 2023, v. 97, n. 5, p. 1429, doi. 10.1007/s00204-023-03466-8

By:

Mukhopadhyay, Chrianjay;
Paul, Manash K.

Publication type:

Article

Off-target activity of NBOMes and NBOMe analogs at the µ opioid receptor.

Published in:

Archives of Toxicology, 2023, v. 97, n. 5, p. 1367, doi. 10.1007/s00204-023-03465-9

By:

Deventer, Marie H.;
Persson, Mattias;
Laus, Antonio;
Pottie, Eline;
Cannaert, Annelies;
Tocco, Graziella;
Gréen, Henrik;
Stove, Christophe P.

Publication type:

Article

PBTK modeling of the pyrrolizidine alkaloid retrorsine to predict liver toxicity in mouse and rat.

Published in:

Archives of Toxicology, 2023, v. 97, n. 5, p. 1319, doi. 10.1007/s00204-023-03453-z

By:

Lehmann, Anja;
Geburek, Ina;
These, Anja;
Hessel-Pras, Stefanie;
Hengstler, Jan G.;
Albrecht, Wiebke;
Mielke, Hans;
Müller-Graf, Christine;
Yang, Xiaojing;
Kloft, Charlotte;
Hethey, Christoph

Publication type:

Article

A mixture of 13 pesticides, contaminants, and food additives below individual NOAELs produces histopathological and organ weight changes in rats.

Published in:

Archives of Toxicology, 2023, v. 97, n. 5, p. 1285, doi. 10.1007/s00204-023-03455-x

By:

Dinca, Viorica;
Docea, Anca Oana;
Drocas, Andrei Ioan;
Nikolouzakis, Taxiarchis Konstantinos;
Stivaktakis, Polychronis D.;
Nikitovic, Dragana;
Golokhvast, Kirill S.;
Hernandez, Antonio F.;
Calina, Daniela;
Tsatsakis, Aristidis

Publication type:

Article