Works matching IS 03405761 AND DT 2018 AND VI 92 AND IP 2

Results: 34

Linking site-specific loss of histone acetylation to repression of gene expression by the mycotoxin ochratoxin A.

Published in:

Archives of Toxicology, 2018, v. 92, n. 2, p. 995, doi. 10.1007/s00204-017-2107-6

By:

Limbeck, Elisabeth;
Vanselow, Jens T.;
Hofmann, Julian;
Schlosser, Andreas;
Mally, Angela

Publication type:

Article

Innovative organotypic in vitro models for safety assessment: aligning with regulatory requirements and understanding models of the heart, skin, and liver as paradigms.

Published in:

Archives of Toxicology, 2018, v. 92, n. 2, p. 557, doi. 10.1007/s00204-018-2152-9

By:

Pridgeon, Chris S.;
Schlott, Constanze;
Wong, Min Wei;
Heringa, Minne B.;
Heckel, Tobias;
Leedale, Joe;
Launay, Laurence;
Gryshkova, Vitalina;
Przyborski, Stefan;
Bearon, Rachel N.;
Wilkinson, Emma L.;
Ansari, Tahera;
Greenman, John;
Hendriks, Delilah F. G.;
Gibbs, Sue;
Sidaway, James;
Sison-Young, Rowena L.;
Walker, Paul;
Cross, Mike J.;
Park, B. Kevin

Publication type:

Article

Highlight report: ‘Big data in the 3R’s: outlook and recommendations’, a roundtable summary.

Published in:

2018

By:

Mahony, C.;
Currie, R.;
Daston, G.;
Kleinstreuer, N.;
van de Water, B.

Publication type:

Editorial

Use of HuH6 and other human-derived hepatoma lines for the detection of genotoxins: a new hope for laboratory animals?

Published in:

Archives of Toxicology, 2018, v. 92, n. 2, p. 921, doi. 10.1007/s00204-017-2109-4

By:

Waldherr, Monika;
Mišík, Miroslav;
Ferk, Franziska;
Tomc, Jana;
Žegura, Bojana;
Filipič, Metka;
Mikulits, Wolfgang;
Mai, Sören;
Haas, Oskar;
Huber, Wolfgang W.;
Haslinger, Elisabeth;
Knasmüller, Siegfried

Publication type:

Article

Determining a threshold sub-acute dose leading to minimal physiological alterations following prolonged exposure to the nerve agent VX in rats.

Published in:

Archives of Toxicology, 2018, v. 92, n. 2, p. 873, doi. 10.1007/s00204-017-2108-5

By:

Bloch-Shilderman, E.;
Rabinovitz, I.;
Egoz, I.;
Yacov, G.;
Allon, N.;
Nili, U.

Publication type:

Article

Microscopy-based high-throughput assays enable multi-parametric analysis to assess adverse effects of nanomaterials in various cell lines.

Published in:

Archives of Toxicology, 2018, v. 92, n. 2, p. 633, doi. 10.1007/s00204-017-2106-7

By:

Hansjosten, Iris;
Rapp, Juliane;
Reiner, Luisa;
Vatter, Ruben;
Fritsch-Decker, Susanne;
Peravali, Ravindra;
Palosaari, Taina;
Joossens, Elisabeth;
Gerloff, Kirsten;
Macko, Peter;
Whelan, Maurice;
Gilliland, Douglas;
Ojea-Jimenez, Isaac;
Monopoli, Marco P.;
Rocks, Louise;
Garry, David;
Dawson, Kenneth;
Röttgermann, Peter J. F.;
Murschhauser, Alexandra;
Rädler, Joachim O.

Publication type:

Article

Protective effect of cadmium-induced autophagy in rat renal mesangial cells.

Published in:

Archives of Toxicology, 2018, v. 92, n. 2, p. 619, doi. 10.1007/s00204-017-2103-x

By:

Fujishiro, Hitomi;
Liu, Ying;
Ahmadi, Bilal;
Templeton, Douglas M.

Publication type:

Article

A novel, integrated in vitro carcinogenicity test to identify genotoxic and non-genotoxic carcinogens using human lymphoblastoid cells.

Published in:

Archives of Toxicology, 2018, v. 92, n. 2, p. 935, doi. 10.1007/s00204-017-2102-y

By:

Wilde, Eleanor C.;
Chapman, Katherine E.;
Stannard, Leanne M.;
Seager, Anna L.;
Brüsehafer, Katja;
Shah, Ume-Kulsoom;
Tonkin, James A.;
Brown, M. Rowan;
Verma, Jatin R.;
Doherty, Ann T.;
Johnson, George E.;
Doak, Shareen H.;
Jenkins, Gareth J. S.

Publication type:

Article

Effect of six oximes on acutely anticholinesterase inhibitor-induced oxidative stress in rat plasma and brain.

Published in:

Archives of Toxicology, 2018, v. 92, n. 2, p. 745, doi. 10.1007/s00204-017-2101-z

By:

Antonijevic, Evica;
Kotur-Stevuljevic, Jelena;
Musilek, Kamil;
Kosvancova, Andrea;
Kuca, Kamil;
Djukic-Cosic, Danijela;
Spasojevic-Kalimanovska, Vesna;
Antonijevic, Biljana

Publication type:

Article

Benchmark dose analyses of multiple genetic toxicity endpoints permit robust, cross-tissue comparisons of MutaMouse responses to orally delivered benzo[a]pyrene.

Published in:

Archives of Toxicology, 2018, v. 92, n. 2, p. 967, doi. 10.1007/s00204-017-2099-2

By:

Long, Alexandra S.;
Wills, John W.;
Krolak, Dorothy;
Guo, Matthew;
Dertinger, Stephen D.;
Arlt, Volker M.;
White, Paul A.

Publication type:

Article

Activation of insulin-like growth factor 1 receptor participates downstream of GPR30 in estradiol-17β-d-glucuronide-induced cholestasis in rats.

Published in:

Archives of Toxicology, 2018, v. 92, n. 2, p. 729, doi. 10.1007/s00204-017-2098-3

By:

Barosso, Ismael R.;
Miszczuk, Gisel S.;
Ciriaci, Nadia;
Andermatten, Romina B.;
Maidagan, Paula M.;
Razori, Valeria;
Taborda, Diego R.;
Roma, Marcelo G.;
Crocenzi, Fernando A.;
Sánchez Pozzi, Enrique J.

Publication type:

Article

Standardisation of defined approaches for skin sensitisation testing to support regulatory use and international adoption: position of the International Cooperation on Alternative Test Methods.

Published in:

Archives of Toxicology, 2018, v. 92, n. 2, p. 611, doi. 10.1007/s00204-017-2097-4

By:

Casati, S.;
Aschberger, K.;
Barroso, J.;
Casey, W.;
Delgado, I.;
Kim, T. S.;
Kleinstreuer, N.;
Kojima, H.;
Lee, J. K.;
Lowit, A.;
Park, H. K.;
Régimbald-Krnel, M. J.;
Strickland, J.;
Whelan, M.;
Yang, Y.;
Zuang, Valérie

Publication type:

Article

Changes in the expression of genes involved in the ovarian function of rats caused by daily exposure to 3-methylcholanthrene and their prevention by α-naphthoflavone.

Published in:

Archives of Toxicology, 2018, v. 92, n. 2, p. 907, doi. 10.1007/s00204-017-2096-5

By:

Rhon-Calderón, Eric Alejandro;
Toro, Carlos Alejandro;
Lomniczi, Alejandro;
Galarza, Rocío Alejandra;
Faletti, Alicia Graciela

Publication type:

Article

Acute regulation of multidrug resistance-associated protein 2 localization and activity by cAMP and estradiol-17β-d-glucuronide in rat intestine and Caco-2 cells.

Published in:

Archives of Toxicology, 2018, v. 92, n. 2, p. 777, doi. 10.1007/s00204-017-2092-9

By:

Tocchetti, Guillermo Nicolás;
Arias, Agostina;
Arana, Maite Rocío;
Rigalli, Juan Pablo;
Domínguez, Camila Juliana;
Zecchinati, Felipe;
Ruiz, María Laura;
Villanueva, Silvina Stella Maris;
Mottino, Aldo Domingo

Publication type:

Article

The effects of the obesogen tributyltin on the metabolism of Sertoli cells cultured ex vivo.

Published in:

Archives of Toxicology, 2018, v. 92, n. 2, p. 601, doi. 10.1007/s00204-017-2091-x

By:

Cardoso, Ana M.;
Alves, Marco G.;
Sousa, Ana C.;
Jarak, Ivana;
Carvalho, Rui A.;
Oliveira, Pedro F.;
Cavaco, José E.;
Rato, Luís

Publication type:

Article

Multiple microRNAs function as self-protective modules in acetaminophen-induced hepatotoxicity in humans.

Published in:

Archives of Toxicology, 2018, v. 92, n. 2, p. 845, doi. 10.1007/s00204-017-2090-y

By:

Yu, Dianke;
Wu, Leihong;
Gill, Pritmohinder;
Tolleson, William H.;
Chen, Si;
Sun, Jinchun;
Knox, Bridgett;
Jin, Yaqiong;
Xiao, Wenming;
Hong, Huixiao;
Wang, Yong;
Ren, Zhen;
Guo, Lei;
Mei, Nan;
Guo, Yongli;
Yang, Xi;
Shi, Leming;
Chen, Yinting;
Zeng, Linjuan;
Dreval, Kostiantyn

Publication type:

Article

GABAA receptor subtype selectivity of the proconvulsant rodenticide TETS.

Published in:

Archives of Toxicology, 2018, v. 92, n. 2, p. 833, doi. 10.1007/s00204-017-2089-4

By:

Pressly, Brandon;
Nguyen, Hai M.;
Wulff, Heike

Publication type:

Article

Respiratory sensitization: toxicological point of view on the available assays.

Published in:

Archives of Toxicology, 2018, v. 92, n. 2, p. 803, doi. 10.1007/s00204-017-2088-5

By:

Chary, Aline;
Hennen, Jennifer;
Klein, Sebastian G.;
Serchi, Tommaso;
Gutleb, Arno C.;
Blömeke, Brunhilde

Publication type:

Article

Hepatotoxic combination effects of three azole fungicides in a broad dose range.

Published in:

Archives of Toxicology, 2018, v. 92, n. 2, p. 859, doi. 10.1007/s00204-017-2087-6

By:

Heise, T.;
Schmidt, F.;
Knebel, C.;
Rieke, S.;
Haider, W.;
Geburek, I.;
Niemann, L.;
Marx-Stoelting, P.

Publication type:

Article

Effects of arsenolipids on in vitro blood-brain barrier model.

Published in:

Archives of Toxicology, 2018, v. 92, n. 2, p. 823, doi. 10.1007/s00204-017-2085-8

By:

Müller, S. M.;
Ebert, F.;
Raber, G.;
Meyer, S.;
Bornhorst, J.;
Hüwel, S.;
Galla, H.-J.;
Francesconi, K. A.;
Schwerdtle, T.

Publication type:

Article

ROS generation and JNK activation contribute to 4-methoxy-TEMPO-induced cytotoxicity, autophagy, and DNA damage in HepG2 cells.

Published in:

Archives of Toxicology, 2018, v. 92, n. 2, p. 717, doi. 10.1007/s00204-017-2084-9

By:

Zhang, Zhuhong;
Ren, Zhen;
Chen, Si;
Guo, Xiaoqing;
Liu, Fang;
Guo, Lei;
Mei, Nan

Publication type:

Article

Intestinal toxicity of deoxynivalenol is limited by <italic>Lactobacillus rhamnosus</italic> RC007 in pig jejunum explants.

Published in:

Archives of Toxicology, 2018, v. 92, n. 2, p. 983, doi. 10.1007/s00204-017-2083-x

By:

García, Gisela Romina;
Payros, Delphine;
Pinton, Philippe;
Dogi, Cecilia Ana;
Laffitte, Joëlle;
Neves, Manon;
González Pereyra, María Laura;
Cavaglieri, Lilia Renée;
Oswald, Isabelle P.

Publication type:

Article

Arylamine <italic>N</italic>-acetyltransferase 1 in situ <italic>N</italic>-acetylation on CD3+ peripheral blood mononuclear cells correlate with NATb mRNA and NAT1 haplotype.

Published in:

Archives of Toxicology, 2018, v. 92, n. 2, p. 661, doi. 10.1007/s00204-017-2082-y

By:

Salazar-González, Raúl A.;
Turiján-Espinoza, Eneida;
Hein, David W.;
Niño-Moreno, Perla C.;
Romano-Moreno, Silvia;
Milán-Segovia, Rosa C.;
Portales-Pérez, Diana P.

Publication type:

Article

Roles of cytosolic phospholipase A2α in reproductive and systemic toxicities in 2,3,7,8-tetrachlorodibenzo-<italic>p</italic>-dioxin-exposed mice.

Published in:

Archives of Toxicology, 2018, v. 92, n. 2, p. 789, doi. 10.1007/s00204-017-2081-z

By:

Fujisawa, Nozomi;
Yoshioka, Wataru;
Yanagisawa, Hiroyuki;
Tohyama, Chiharu

Publication type:

Article

Mesenchyme-derived factors enhance preneoplastic growth by non-genotoxic carcinogens in rat liver.

Published in:

Archives of Toxicology, 2018, v. 92, n. 2, p. 953, doi. 10.1007/s00204-017-2080-0

By:

Nejabat, Marzieh;
Riegler, Teresa;
Reitinger, Tabea;
Subosits, Sandra;
Römer, Michael;
Eichner, Johannes;
Bilban, Martin;
Zell, Andreas;
Huber, Wolfgang W.;
Schulte-Hermann, Rolf;
Grasl-Kraupp, Bettina

Publication type:

Article

Prediction of liver toxicity and mode of action using metabolomics in vitro in HepG2 cells.

Published in:

Archives of Toxicology, 2018, v. 92, n. 2, p. 893, doi. 10.1007/s00204-017-2079-6

By:

Ramirez, Tzutzuy;
Strigun, Alexander;
Verlohner, Andreas;
Huener, Hans-Albrecht;
Peter, Erik;
Herold, Michael;
Bordag, Natalie;
Mellert, Werner;
Walk, Tilmann;
Spitzer, Michael;
Jiang, Xiaoqi;
Sperber, Saskia;
Hofmann, Thomas;
Hartung, Thomas;
Kamp, Hennicke;
van Ravenzwaay, Ben

Publication type:

Article

Toxicokinetic of tris(2-butoxyethyl) phosphate (TBOEP) in humans following single oral administration.

Published in:

Archives of Toxicology, 2018, v. 92, n. 2, p. 651, doi. 10.1007/s00204-017-2078-7

By:

Völkel, Wolfgang;
Fuchs, Veronika;
Wöckner, Mandy;
Fromme, Hermann

Publication type:

Article

PFOS induces proliferation, cell-cycle progression, and malignant phenotype in human breast epithelial cells.

Published in:

Archives of Toxicology, 2018, v. 92, n. 2, p. 705, doi. 10.1007/s00204-017-2077-8

By:

Pierozan, Paula;
Karlsson, Oskar

Publication type:

Article

Arsenite and methylarsonite inhibit mitochondrial metabolism and glucose-stimulated insulin secretion in INS-1 832/13 β cells.

Published in:

Archives of Toxicology, 2018, v. 92, n. 2, p. 693, doi. 10.1007/s00204-017-2074-y

By:

Dover, E. N.;
Beck, R.;
Huang, M. C.;
Douillet, C.;
Wang, Z.;
Klett, E. L.;
Stýblo, Miroslav

Publication type:

Article

Protective effects of the resveratrol analog piceid in dopaminergic SH-SY5Y cells.

Published in:

Archives of Toxicology, 2018, v. 92, n. 2, p. 669, doi. 10.1007/s00204-017-2073-z

By:

Potdar, Sneha;
Parmar, Mayur S.;
Ray, Sidhartha D.;
Cavanaugh, Jane E.

Publication type:

Article

P21Waf1/Cip1 depletion promotes dexamethasone-induced apoptosis in osteoblastic MC3T3-E1 cells by inhibiting the Nrf2/HO-1 pathway.

Published in:

Archives of Toxicology, 2018, v. 92, n. 2, p. 679, doi. 10.1007/s00204-017-2070-2

By:

Han, Dandan;
Gao, Jian;
Gu, Xiaolong;
Hengstler, Jan Georg;
Zhang, Limei;
Shahid, Muhammad;
Ali, Tariq;
Han, Bo

Publication type:

Article

Comparative developmental toxicity of a comprehensive suite of polycyclic aromatic hydrocarbons.

Published in:

Archives of Toxicology, 2018, v. 92, n. 2, p. 571, doi. 10.1007/s00204-017-2068-9

By:

Geier, Mitra C.;
Chlebowski, Anna C.;
Truong, Lisa;
Massey Simonich, Staci L.;
Anderson, Kim A.;
Tanguay, Robert L.

Publication type:

Article

Predicting in vivo effect levels for repeat-dose systemic toxicity using chemical, biological, kinetic and study covariates.

Published in:

Archives of Toxicology, 2018, v. 92, n. 2, p. 587, doi. 10.1007/s00204-017-2067-x

By:

Truong, Lisa;
Ouedraogo, Gladys;
Pham, LyLy;
Clouzeau, Jacques;
Loisel-Joubert, Sophie;
Blanchet, Delphine;
Noçairi, Hicham;
Setzer, Woodrow;
Judson, Richard;
Grulke, Chris;
Mansouri, Kamel;
Martin, Matthew

Publication type:

Article

<italic>t</italic>-BuOOH induces ferroptosis in human and murine cell lines.

Published in:

Archives of Toxicology, 2018, v. 92, n. 2, p. 759, doi. 10.1007/s00204-017-2066-y

By:

Wenz, Christine;
Faust, Dagmar;
Linz, Berenike;
Turmann, Christian;
Nikolova, Teodora;
Bertin, John;
Gough, Peter;
Wipf, Peter;
Schröder, Anna Sophia;
Krautwald, Stefan;
Dietrich, Cornelia

Publication type:

Article

Works matching IS 03405761 AND DT 2018 AND VI 92 AND IP 2

Linking site-specific loss of histone acetylation to repression of gene expression by the mycotoxin ochratoxin A.

Innovative organotypic in vitro models for safety assessment: aligning with regulatory requirements and understanding models of the heart, skin, and liver as paradigms.

Highlight report: ‘Big data in the 3R’s: outlook and recommendations’, a roundtable summary.

Use of HuH6 and other human-derived hepatoma lines for the detection of genotoxins: a new hope for laboratory animals?

Determining a threshold sub-acute dose leading to minimal physiological alterations following prolonged exposure to the nerve agent VX in rats.

Microscopy-based high-throughput assays enable multi-parametric analysis to assess adverse effects of nanomaterials in various cell lines.

Protective effect of cadmium-induced autophagy in rat renal mesangial cells.

A novel, integrated in vitro carcinogenicity test to identify genotoxic and non-genotoxic carcinogens using human lymphoblastoid cells.

Effect of six oximes on acutely anticholinesterase inhibitor-induced oxidative stress in rat plasma and brain.

Benchmark dose analyses of multiple genetic toxicity endpoints permit robust, cross-tissue comparisons of MutaMouse responses to orally delivered benzo[a]pyrene.

Activation of insulin-like growth factor 1 receptor participates downstream of GPR30 in estradiol-17β-d-glucuronide-induced cholestasis in rats.

Standardisation of defined approaches for skin sensitisation testing to support regulatory use and international adoption: position of the International Cooperation on Alternative Test Methods.

Changes in the expression of genes involved in the ovarian function of rats caused by daily exposure to 3-methylcholanthrene and their prevention by α-naphthoflavone.

Acute regulation of multidrug resistance-associated protein 2 localization and activity by cAMP and estradiol-17β-d-glucuronide in rat intestine and Caco-2 cells.

The effects of the obesogen tributyltin on the metabolism of Sertoli cells cultured ex vivo.

Multiple microRNAs function as self-protective modules in acetaminophen-induced hepatotoxicity in humans.

GABA<sub>A</sub> receptor subtype selectivity of the proconvulsant rodenticide TETS.

Respiratory sensitization: toxicological point of view on the available assays.

Hepatotoxic combination effects of three azole fungicides in a broad dose range.

Effects of arsenolipids on in vitro blood-brain barrier model.

ROS generation and JNK activation contribute to 4-methoxy-TEMPO-induced cytotoxicity, autophagy, and DNA damage in HepG2 cells.

Intestinal toxicity of deoxynivalenol is limited by <italic>Lactobacillus rhamnosus</italic> RC007 in pig jejunum explants.

Arylamine <italic>N</italic>-acetyltransferase 1 in situ <italic>N</italic>-acetylation on CD3+ peripheral blood mononuclear cells correlate with NATb mRNA and NAT1 haplotype.

Roles of cytosolic phospholipase A<sub>2</sub>α in reproductive and systemic toxicities in 2,3,7,8-tetrachlorodibenzo-<italic>p</italic>-dioxin-exposed mice.

Mesenchyme-derived factors enhance preneoplastic growth by non-genotoxic carcinogens in rat liver.

Prediction of liver toxicity and mode of action using metabolomics in vitro in HepG2 cells.

Toxicokinetic of tris(2-butoxyethyl) phosphate (TBOEP) in humans following single oral administration.

PFOS induces proliferation, cell-cycle progression, and malignant phenotype in human breast epithelial cells.

Arsenite and methylarsonite inhibit mitochondrial metabolism and glucose-stimulated insulin secretion in INS-1 832/13 β cells.

Protective effects of the resveratrol analog piceid in dopaminergic SH-SY5Y cells.

P21<sup>Waf1/Cip1</sup> depletion promotes dexamethasone-induced apoptosis in osteoblastic MC3T3-E1 cells by inhibiting the Nrf2/HO-1 pathway.

Comparative developmental toxicity of a comprehensive suite of polycyclic aromatic hydrocarbons.

Predicting in vivo effect levels for repeat-dose systemic toxicity using chemical, biological, kinetic and study covariates.

<italic>t</italic>-BuOOH induces ferroptosis in human and murine cell lines.