Works matching IS 03405761 AND DT 2017 AND VI 91 AND IP 3

Results: 32

A multicenter assessment of single-cell models aligned to standard measures of cell health for prediction of acute hepatotoxicity.

Published in:

Archives of Toxicology, 2017, v. 91, n. 3, p. 1385, doi. 10.1007/s00204-016-1745-4

By:

Sison-Young, Rowena;
Lauschke, Volker;
Johann, Esther;
Alexandre, Eliane;
Antherieu, Sébastien;
Aerts, Hélène;
Gerets, Helga;
Labbe, Gilles;
Hoët, Delphine;
Dorau, Martina;
Schofield, Christopher;
Lovatt, Cerys;
Holder, Julie;
Stahl, Simone;
Richert, Lysiane;
Kitteringham, Neil;
Jones, Robert;
Elmasry, Mohamed;
Weaver, Richard;
Hewitt, Philip G.

Publication type:

Article

R-Limonene metabolism in humans and metabolite kinetics after oral administration.

Published in:

Archives of Toxicology, 2017, v. 91, n. 3, p. 1175, doi. 10.1007/s00204-016-1751-6

By:

Schmidt, Lukas;
Göen, Thomas

Publication type:

Article

Activation of the Nrf2 signaling pathway in usnic acid-induced toxicity in HepG2 cells.

Published in:

Archives of Toxicology, 2017, v. 91, n. 3, p. 1293, doi. 10.1007/s00204-016-1775-y

By:

Chen, Si;
Zhang, Zhuhong;
Qing, Tao;
Ren, Zhen;
Yu, Dianke;
Couch, Letha;
Ning, Baitang;
Mei, Nan;
Shi, Leming;
Tolleson, William;
Guo, Lei

Publication type:

Article

Pseudocatalytic scavenging of the nerve agent VX with human blood components and the oximes obidoxime and HI-6.

Published in:

Archives of Toxicology, 2017, v. 91, n. 3, p. 1309, doi. 10.1007/s00204-016-1776-x

By:

Wille, Timo;
Wellen, Jens;
Thiermann, Horst;
Worek, Franz

Publication type:

Article

In vitro hepatotoxicity of 'Legal X': the combination of 1-benzylpiperazine (BZP) and 1-(m-trifluoromethylphenyl)piperazine (TFMPP) triggers oxidative stress, mitochondrial impairment and apoptosis.

Published in:

Archives of Toxicology, 2017, v. 91, n. 3, p. 1413, doi. 10.1007/s00204-016-1777-9

By:

Dias da Silva, Diana;
Silva, Maria;
Moreira, Patrícia;
Martins, Maria;
Valente, Maria;
Carvalho, Félix;
Bastos, Maria de;
Carmo, Helena

Publication type:

Article

Validation of precision-cut liver slices to study drug-induced cholestasis: a transcriptomics approach.

Published in:

Archives of Toxicology, 2017, v. 91, n. 3, p. 1401, doi. 10.1007/s00204-016-1778-8

By:

Vatakuti, Suresh;
Olinga, Peter;
Pennings, Jeroen;
Groothuis, Geny

Publication type:

Article

Phtalates: new cardiovascular health disruptors?

Published in:

2017

By:

Muscogiuri, Giovanna;
Colao, Annamaria

Publication type:

Editorial

High-content imaging-based BAC-GFP toxicity pathway reporters to assess chemical adversity liabilities.

Published in:

Archives of Toxicology, 2017, v. 91, n. 3, p. 1367, doi. 10.1007/s00204-016-1781-0

By:

Wink, Steven;
Hiemstra, Steven;
Herpers, Bram;
Water, Bob

Publication type:

Article

A protocol to determine dermal absorption of xenobiotica through human skin in vitro.

Published in:

Archives of Toxicology, 2017, v. 91, n. 3, p. 1497, doi. 10.1007/s00204-016-1782-z

By:

Fabian, Eric;
Oesch, Franz;
Ott, Katharina;
Landsiedel, Robert;
Ravenzwaay, Bennard

Publication type:

Article

Sirtuin 1-dependent resveratrol cytotoxicity and pro-differentiation activity on breast cancer cells.

Published in:

Archives of Toxicology, 2017, v. 91, n. 3, p. 1261, doi. 10.1007/s00204-016-1784-x

By:

Deus, Cláudia;
Serafim, Teresa;
Magalhães-Novais, Silvia;
Vilaça, Andreia;
Moreira, Ana;
Sardão, Vilma;
Cardoso, Susana;
Oliveira, Paulo

Publication type:

Article

Oxidative stress caused by a SOD1 deficiency ameliorates thioacetamide-triggered cell death via CYP2E1 inhibition but stimulates liver steatosis.

Published in:

Archives of Toxicology, 2017, v. 91, n. 3, p. 1319, doi. 10.1007/s00204-016-1785-9

By:

Shirato, Takaya;
Homma, Takujiro;
Lee, Jaeyong;
Kurahashi, Toshihiro;
Fujii, Junichi

Publication type:

Article

Furan-induced transcriptomic and gene-specific DNA methylation changes in the livers of Fischer 344 rats in a 2-year carcinogenicity study.

Published in:

Archives of Toxicology, 2017, v. 91, n. 3, p. 1233, doi. 10.1007/s00204-016-1786-8

By:

Tryndyak, Volodymyr;
Conti, Aline;
Doerge, Daniel;
Olson, Greg;
Beland, Frederick;
Pogribny, Igor

Publication type:

Article

Cytotoxic effects of the anthraquinone derivatives 1′-deoxyrhodoptilometrin and ( S)-(−)-rhodoptilometrin isolated from the marine echinoderm Comanthus sp.

Published in:

Archives of Toxicology, 2017, v. 91, n. 3, p. 1485, doi. 10.1007/s00204-016-1787-7

By:

Wätjen, Wim;
Ebada, Sherif;
Bergermann, Anja;
Chovolou, Yvonni;
Totzke, Frank;
Kubbutat, Michael;
Lin, Wenhan;
Proksch, Peter

Publication type:

Article

Alpha-synuclein-induced oxidative stress correlates with altered superoxide dismutase and glutathione synthesis in human neuroblastoma SH-SY5Y cells.

Published in:

Archives of Toxicology, 2017, v. 91, n. 3, p. 1245, doi. 10.1007/s00204-016-1788-6

By:

Perfeito, Rita;
Ribeiro, Márcio;
Rego, A.

Publication type:

Article

Humanizing the zebrafish liver shifts drug metabolic profiles and improves pharmacokinetics of CYP3A4 substrates.

Published in:

Archives of Toxicology, 2017, v. 91, n. 3, p. 1187, doi. 10.1007/s00204-016-1789-5

By:

Poon, Kar;
Wang, Xingang;
Ng, Ashley;
Goh, Wei;
McGinnis, Claudia;
Fowler, Stephen;
Carney, Tom;
Wang, Haishan;
Ingham, Phillip

Publication type:

Article

Di (2-ethylhexyl) phthalate impairs steroidogenesis in ovarian follicular cells of prepuberal mice.

Published in:

Archives of Toxicology, 2017, v. 91, n. 3, p. 1279, doi. 10.1007/s00204-016-1790-z

By:

Lai, Fang-Nong;
Liu, Jing-Cai;
Li, Lan;
Ma, Jun-Yu;
Liu, Xue-Lian;
Liu, Yu-Ping;
Zhang, Xi-Feng;
Chen, Hong;
Felici, Massimo;
Dyce, Paul;
Shen, Wei

Publication type:

Article

Hepatocyte spheroids as a competent in vitro system for drug biotransformation studies: nevirapine as a bioactivation case study.

Published in:

Archives of Toxicology, 2017, v. 91, n. 3, p. 1199, doi. 10.1007/s00204-016-1792-x

By:

Pinheiro, Pedro;
Pereira, Sofia;
Harjivan, Shrika;
Martins, Inês;
Marinho, Aline;
Cipriano, Madalena;
Jacob, Cristina;
Oliveira, Nuno;
Castro, Matilde;
Marques, M.;
Antunes, Alexandra;
Miranda, Joana

Publication type:

Article

Plasma-specific microRNA response induced by acute exposure to aristolochic acid I in rats.

Published in:

Archives of Toxicology, 2017, v. 91, n. 3, p. 1473, doi. 10.1007/s00204-016-1791-y

By:

Pu, Xue-yan;
Shen, Jia-ying;
Deng, Zhong-ping;
Zhang, Ze-an

Publication type:

Article

Epidermal growth factor prevents thallium(I)- and thallium(III)-mediated rat pheochromocytoma (PC12) cell apoptosis.

Published in:

Archives of Toxicology, 2017, v. 91, n. 3, p. 1157, doi. 10.1007/s00204-016-1793-9

By:

Pino, María;
Marotte, Clarisa;
Verstraeten, Sandra

Publication type:

Article

The intestinal barrier as an emerging target in the toxicological assessment of mycotoxins.

Published in:

Archives of Toxicology, 2017, v. 91, n. 3, p. 1007, doi. 10.1007/s00204-016-1794-8

By:

Akbari, Peyman;
Braber, Saskia;
Varasteh, Soheil;
Alizadeh, Arash;
Garssen, Johan;
Fink-Gremmels, Johanna

Publication type:

Article

Synergistic estrogenic effects of Fusarium and Alternaria mycotoxins in vitro.

Published in:

Archives of Toxicology, 2017, v. 91, n. 3, p. 1447, doi. 10.1007/s00204-016-1795-7

By:

Vejdovszky, Katharina;
Hahn, Kathrin;
Braun, Dominik;
Warth, Benedikt;
Marko, Doris

Publication type:

Article

BMP9 a possible alternative drug for the recently withdrawn BMP7? New perspectives for (re-)implementation by personalized medicine.

Published in:

Archives of Toxicology, 2017, v. 91, n. 3, p. 1353, doi. 10.1007/s00204-016-1796-6

By:

Sreekumar, Vrinda;
Aspera-Werz, Romina;
Tendulkar, Gauri;
Reumann, Marie;
Freude, Thomas;
Breitkopf-Heinlein, Katja;
Dooley, Steven;
Pscherer, Stefan;
Ochs, Björn;
Flesch, Ingo;
Hofmann, Valeska;
Nussler, Andreas;
Ehnert, Sabrina

Publication type:

Article

Protein bio-corona: critical issue in immune nanotoxicology.

Published in:

Archives of Toxicology, 2017, v. 91, n. 3, p. 1031, doi. 10.1007/s00204-016-1797-5

By:

Neagu, Monica;
Piperigkou, Zoi;
Karamanou, Konstantina;
Engin, Ayse;
Docea, Anca;
Constantin, Carolina;
Negrei, Carolina;
Nikitovic, Dragana;
Tsatsakis, Aristidis

Publication type:

Article

Structure-activity relationship of ochratoxin A and synthesized derivatives: importance of amino acid and halogen moiety for cytotoxicity.

Published in:

Archives of Toxicology, 2017, v. 91, n. 3, p. 1461, doi. 10.1007/s00204-016-1799-3

By:

Rottkord, Ulrike;
Röhl, Christopher;
Ferse, Ines;
Schulz, Marie-Christin;
Rückschloss, Uwe;
Gekle, Michael;
Schwerdt, Gerald;
Humpf, Hans-Ulrich

Publication type:

Article

Glucuronidation of 4- tert-octylphenol in humans, monkeys, rats, and mice: an in vitro analysis using liver and intestine microsomes.

Published in:

Archives of Toxicology, 2017, v. 91, n. 3, p. 1227, doi. 10.1007/s00204-016-1800-1

By:

Hanioka, Nobumitsu;
Isobe, Takashi;
Ohkawara, Susumu;
Tanaka-Kagawa, Toshiko;
Jinno, Hideto

Publication type:

Article

Impact of phase I metabolism on uptake, oxidative stress and genotoxicity of the emerging mycotoxin alternariol and its monomethyl ether in esophageal cells.

Published in:

Archives of Toxicology, 2017, v. 91, n. 3, p. 1213, doi. 10.1007/s00204-016-1801-0

By:

Tiessen, Christine;
Ellmer, Doris;
Mikula, Hannes;
Pahlke, Gudrun;
Warth, Benedikt;
Gehrke, Helge;
Zimmermann, Kristin;
Heiss, Elke;
Fröhlich, Johannes;
Marko, Doris

Publication type:

Article

Why did researchers not use realistic doses in animal studies of bisphenol A?

Published in:

2017

By:

Völkel, Wolfgang

Publication type:

Editorial

In vivo imaging of systemic transport and elimination of xenobiotics and endogenous molecules in mice.

Published in:

Archives of Toxicology, 2017, v. 91, n. 3, p. 1335, doi. 10.1007/s00204-016-1906-5

By:

Reif, Raymond;
Ghallab, Ahmed;
Beattie, Lynette;
Günther, Georgia;
Kuepfer, Lars;
Kaye, Paul;
Hengstler, Jan

Publication type:

Article

An evidence-based review of the genotoxic and reproductive effects of sulfur mustard.

Published in:

Archives of Toxicology, 2017, v. 91, n. 3, p. 1143, doi. 10.1007/s00204-016-1911-8

By:

Khan, Fazlullah;
Niaz, Kamal;
Ismail Hassan, Fatima;
Abdollahi, Mohammad

Publication type:

Article

Cyanotoxins: producing organisms, occurrence, toxicity, mechanism of action and human health toxicological risk evaluation.

Published in:

Archives of Toxicology, 2017, v. 91, n. 3, p. 1049, doi. 10.1007/s00204-016-1913-6

By:

Buratti, Franca;
Manganelli, Maura;
Vichi, Susanna;
Stefanelli, Mara;
Scardala, Simona;
Testai, Emanuela;
Funari, Enzo

Publication type:

Article

Susceptibility to chronic inflammation: an update.

Published in:

Archives of Toxicology, 2017, v. 91, n. 3, p. 1131, doi. 10.1007/s00204-016-1914-5

By:

Nasef, Noha;
Mehta, Sunali;
Ferguson, Lynnette

Publication type:

Article

Chloroquine derivatives block the translocation pores and inhibit cellular entry of Clostridium botulinum C2 toxin and Bacillus anthracis lethal toxin.

Published in:

Archives of Toxicology, 2017, v. 91, n. 3, p. 1431, doi. 10.1007/s00204-016-1716-9

By:

Kreidler, Anna-Maria;
Benz, Roland;
Barth, Holger

Publication type:

Article