Works matching IS 03065251 AND DT 1985 AND VI 19 AND IP S2

Results: 27

Reproducibility of oxprenolol plasma concentrations in young female volunteers following oral administration of an oxprenolol Oros dosage form.

Published in:

British Journal of Clinical Pharmacology, 1985, v. 19, n. S2, p. 185S, doi. 10.1111/j.1365-2125.1985.tb02760.x

By:

Jack, DB;
Kendall, MJ;
Laugher, SJ;
Smith, SR

Publication type:

Article

Investigation of drug absorption from the gastrointestinal tract of man. V. Effect of the beta-adrenoceptor antagonist, metoprolol, on postprandial gastric function.

Published in:

British Journal of Clinical Pharmacology, 1985, v. 19, n. S2, p. 127S, doi. 10.1111/j.1365-2125.1985.tb02753.x

By:

Jobin, G;
Cortot, A;
Danquechin-Dorval, E;
Godbillon, J;
Schoeller, JP;
Bernier, JJ;
Hirtz, J

Publication type:

Article

Exercise and resting blood pressure and heart rate changes 24 h after dosing in patients with essential hypertension receiving 16/260 oxprenolol Oros once daily.

Published in:

British Journal of Clinical Pharmacology, 1985, v. 19, n. S2, p. 207S, doi. 10.1111/j.1365-2125.1985.tb02764.x

By:

Muller, FB;
Allsopp, LF;
Cooper, GL;
Bolli, P;
Frei, P;
Glaus, L;
Ritz, R;
Buhler, FR

Publication type:

Article

The gastrointestinal absorption of drugs in man: a review of current concepts and methods of investigation.

Published in:

British Journal of Clinical Pharmacology, 1985, v. 19, n. S2, p. 77S, doi. 10.1111/j.1365-2125.1985.tb02746.x

By:

Hirtz, J

Publication type:

Article

Pharmacokinetic investigation of the absorption of oxprenolol from Oros delivery systems in healthy volunteers: comparison of in vivo and in vitro drug release.

Published in:

British Journal of Clinical Pharmacology, 1985, v. 19, n. S2, p. 163S, doi. 10.1111/j.1365-2125.1985.tb02757.x

By:

Bradbrook, ID;
John, VA;
Morrison, PJ;
Rogers, HJ;
Spector, RG

Publication type:

Article

Oros controlled-release formulations of metoprolol: an approach to the development of a system for once daily administration.

Published in:

British Journal of Clinical Pharmacology, 1985, v. 19, n. S2, p. 231S, doi. 10.1111/j.1365-2125.1985.tb02768.x

By:

Good, W;
Leeson, LJ;
Zak, SL;
Wagner, WE;
Meeker, JB;
Arnold, JD

Publication type:

Article

Influence of food on the absorption of metoprolol administered as an Oros drug delivery system to man.

Published in:

British Journal of Clinical Pharmacology, 1985, v. 19, n. S2, p. 245S, doi. 10.1111/j.1365-2125.1985.tb02770.x

By:

Lecaillon, JB;
Massias, P;
Schoeller, JP;
Abadie, F

Publication type:

Article

Investigation of drug absorption from the gastrointestinal tract of man. IV. Influence of food and digestive secretions on metoprolol jejunal absorption.

Published in:

British Journal of Clinical Pharmacology, 1985, v. 19, n. S2, p. 119S, doi. 10.1111/j.1365-2125.1985.tb02752.x

By:

Evard, D;
Vidon, N;
Godbillon, J;
Bovet, M;
Duval, M;
Schoeller, JP;
Bernier, JJ;
Hirtz, J

Publication type:

Article

Gastrointestinal transit of Oros drug delivery systems in healthy volunteers: a short report.

Published in:

British Journal of Clinical Pharmacology, 1985, v. 19, n. S2, p. 203S, doi. 10.1111/j.1365-2125.1985.tb02763.x

By:

John, VA;
Shotton, PA;
Moppert, J;
Theobald, W

Publication type:

Article

Osmotic delivery systems for the beta-adrenoceptor antagonists metoprolol and oxprenolol: design and evaluation of systems for once- daily administration.

Published in:

British Journal of Clinical Pharmacology, 1985, v. 19, n. S2, p. 69S, doi. 10.1111/j.1365-2125.1985.tb02745.x

By:

Theeuwes, F;
Swanson, DR;
Guittard, G;
Ayer, A;
Khanna, S

Publication type:

Article

In vitro and in vivo deconvolution assessment of drug release kinetics from oxprenolol Oros preparations.

Published in:

British Journal of Clinical Pharmacology, 1985, v. 19, n. S2, p. 151S, doi. 10.1111/j.1365-2125.1985.tb02756.x

By:

Langenbucher, F;
Mysicka, J

Publication type:

Article

Comparison of single-dose pharmacokinetic and pharmacodynamic properties of two metoprolol Oros systems with different initial zero- order release rates.

Published in:

British Journal of Clinical Pharmacology, 1985, v. 19, n. S2, p. 225S, doi. 10.1111/j.1365-2125.1985.tb02767.x

By:

Warrington, SJ;
Barclay, SP;
John, VA;
Shotton, PA;
Good, W

Publication type:

Article

Investigation of drug absorption from the gastrointestinal tract of man. I. Metoprolol in the stomach, duodenum and jejunum.

Published in:

British Journal of Clinical Pharmacology, 1985, v. 19, n. S2, p. 97S, doi. 10.1111/j.1365-2125.1985.tb02749.x

By:

Jobin, G;
Cortot, A;
Godbillon, J;
Duval, M;
Schoeller, JP;
Hirtz, J;
Bernier, JJ

Publication type:

Article

Investigation of drug absorption from the gastrointestinal tract of man. III. Metoprolol in the colon.

Published in:

British Journal of Clinical Pharmacology, 1985, v. 19, n. S2, p. 113S, doi. 10.1111/j.1365-2125.1985.tb02751.x

By:

Godbillon, J;
Evard, D;
Vidon, N;
Duval, M;
Schoeller, JP;
Bernier, JJ;
Hirtz, J

Publication type:

Article

Pre-dosing plasma concentrations and beta-adrenoceptor blocking effects during repeated once daily dosing with 160 mg sustained-release propranolol (Inderal LA) and 16/260 oxprenolol Oros to healthy volunteers.

Published in:

British Journal of Clinical Pharmacology, 1985, v. 19, n. S2, p. 197S, doi. 10.1111/j.1365-2125.1985.tb02762.x

By:

Moppert, J;
Degen, PH;
Racine-Poon, A

Publication type:

Article

The role of clinical pharmacology in the development and evaluation of oral controlled-release dosage forms.

Published in:

British Journal of Clinical Pharmacology, 1985, v. 19, n. S2, p. 65S, doi. 10.1111/j.1365-2125.1985.tb02744.x

By:

Kendall, MJ;
John, VA

Publication type:

Article

Concentration-effect relationship of oxprenolol in healthy volunteers: a retrospective analysis.

Published in:

British Journal of Clinical Pharmacology, 1985, v. 19, n. S2, p. 143S, doi. 10.1111/j.1365-2125.1985.tb02755.x

By:

Racine-Poon, A;
Moppert, J

Publication type:

Article

Influence of site of drug delivery on the systemic availability of metoprolol: comparison of intragastric infusion and 14/190 Oros administration.

Published in:

British Journal of Clinical Pharmacology, 1985, v. 19, n. S2, p. 219S, doi. 10.1111/j.1365-2125.1985.tb02766.x

By:

Warrington, SJ;
Barclay, SP;
John, VA;
Shotton, PA;
Wardle, HM;
Good, W

Publication type:

Article

Evaluation of oxprenolol and metoprolol Oros systems in the dog: comparison of in vivo and in vitro drug release, and of drug absorption from duodenal and colonic infusion sites.

Published in:

British Journal of Clinical Pharmacology, 1985, v. 19, n. S2, p. 91S, doi. 10.1111/j.1365-2125.1985.tb02748.x

By:

Fara, JW;
Myrback, RE;
Swanson, DR

Publication type:

Article

A multiple dose comparative study of the pharmacodynamic and pharmacokinetic behaviour of polymer-matrix and Oros dosage forms of oxprenolol in healthy volunteers.

Published in:

British Journal of Clinical Pharmacology, 1985, v. 19, n. S2, p. 177S, doi. 10.1111/j.1365-2125.1985.tb02759.x

By:

Woods, KL;
Jack, DB;
Kendall, MJ;
Halsey, A;
O'Donnell, ML;
Warrington, SJ;
John, VA

Publication type:

Article

Investigation of drug absorption from the gastrointestinal tract of man. II. Metoprolol in the jejunum and ileum.

Published in:

British Journal of Clinical Pharmacology, 1985, v. 19, n. S2, p. 107S, doi. 10.1111/j.1365-2125.1985.tb02750.x

By:

Vidon, N;
Evard, D;
Godbillon, J;
Rongier, M;
Duval, M;
Schoeller, JP;
Bernier, JJ;
Hirtz, J

Publication type:

Article

Influence of food intake on plasma oxprenolol concentrations following oral administration of conventional and Oros preparations.

Published in:

British Journal of Clinical Pharmacology, 1985, v. 19, n. S2, p. 191S, doi. 10.1111/j.1365-2125.1985.tb02761.x

By:

John, VA;
Smith, SE

Publication type:

Article

Oxprenolol absorption in man after single bolus dosing into two segments of the colon compared with that after oral dosing.

Published in:

British Journal of Clinical Pharmacology, 1985, v. 19, n. S2, p. 137S, doi. 10.1111/j.1365-2125.1985.tb02754.x

By:

Antonin, KH;
Bieck, P;
Scheurlen, M;
Jedrychowski, M;
Malchow, H

Publication type:

Article

Osmotically controlled-delivery of metoprolol in man: in vivo performance of Oros systems with different durations of drug release.

Published in:

British Journal of Clinical Pharmacology, 1985, v. 19, n. S2, p. 213S, doi. 10.1111/j.1365-2125.1985.tb02765.x

By:

Godbillon, J;
Gerardin, A;
Richard, J;
Leroy, D;
Moppert, J

Publication type:

Article

Gastric, intestinal and colonic absorption of metoprolol in the rat.

Published in:

British Journal of Clinical Pharmacology, 1985, v. 19, n. S2, p. 85S, doi. 10.1111/j.1365-2125.1985.tb02747.x

By:

Domenech, J;
Alba, M;
Morera, JM;
Obach, R;
Pla Delfina, JM

Publication type:

Article

Single-dose pharmacokinetic and pharmacodynamic comparison of polymer- matrix (Slow Trasicor) and Oros dosage forms of oxprenolol in healthy volunteers.

Published in:

British Journal of Clinical Pharmacology, 1985, v. 19, n. S2, p. 171S, doi. 10.1111/j.1365-2125.1985.tb02758.x

By:

Bennett, PN;
Bennett, J;
Bradbrook, I;
Francis, J;
John, VA;
Rogers, H;
Turner, P;
Warrington, SJ

Publication type:

Article

A multiple dose pharmacokinetic and pharmacodynamic evaluation of conventional and 19/285 Oros formulations of metoprolol in healthy volunteers.

Published in:

British Journal of Clinical Pharmacology, 1985, v. 19, n. S2, p. 239S, doi. 10.1111/j.1365-2125.1985.tb02769.x

By:

Grainger, SL;
John, VA;
Shotton, PA;
Smith, SE

Publication type:

Article