Works matching IS 03051048 AND DT 2022 AND VI 50 AND IP 12

Results: 43

From bench to bedside: Improving the clinical safety of GalNAc–siRNA conjugates using seed-pairing destabilization.

Published in:

Nucleic Acids Research, 2022, v. 50, n. 12, p. 6656, doi. 10.1093/nar/gkac539

By:

Schlegel, Mark K;
Janas, Maja M;
Jiang, Yongfeng;
Barry, Joseph D;
Davis, Wendell;
Agarwal, Saket;
Berman, Daniel;
Brown, Christopher R;
Castoreno, Adam;
LeBlanc, Sarah;
Liebow, Abigail;
Mayo, Tara;
Milstein, Stuart;
Nguyen, Tuyen;
Shulga-Morskaya, Svetlana;
Hyde, Sarah;
Schofield, Sally;
Szeto, John;
Woods, Lauren Blair;
Yilmaz, Vedat O

Publication type:

Article

dual-activity topoisomerase complex regulates mRNA translation and turnover.

Published in:

Nucleic Acids Research, 2022, v. 50, n. 12, p. 7013, doi. 10.1093/nar/gkac538

By:

Su, Shuaikun;
Xue, Yutong;
Sharov, Alexei;
Zhang, Yongqing;
Lee, Seung Kyu;
Martindale, Jennifer L;
Li, Wen;
Ku, Wai Lim;
Zhao, Keji;
De, Supriyo;
Shen, Weiping;
Sen, Payel;
Gorospe, Myriam;
Xu, Dongyi;
Wang, Weidong

Publication type:

Article

DNA G-quadruplex structure participates in regulation of lipid metabolism through acyl-CoA binding protein.

Published in:

Nucleic Acids Research, 2022, v. 50, n. 12, p. 6953, doi. 10.1093/nar/gkac527

By:

Xiang, Lijun;
Niu, Kangkang;
Peng, Yuling;
Zhang, Xiaojuan;
Li, Xiaoyu;
Ye, Ruoqi;
Yu, Guoxing;
Ye, Guojun;
Xiang, Hui;
Song, Qisheng;
Feng, Qili

Publication type:

Article

Structural and dynamic studies of DNA recognition by NF-κB p50 RHR homodimer using methyl NMR spectroscopy.

Published in:

Nucleic Acids Research, 2022, v. 50, n. 12, p. 7147, doi. 10.1093/nar/gkac535

By:

Singh, Amrinder;
Martinez-Yamout, Maria A;
Wright, Peter E;
Dyson, H Jane

Publication type:

Article

H3K36me2 methyltransferase NSD2 orchestrates epigenetic reprogramming during spermatogenesis.

Published in:

Nucleic Acids Research, 2022, v. 50, n. 12, p. 6786, doi. 10.1093/nar/gkac533

By:

Li, Zhiming;
Zhang, Xinzong;
Xie, Shiming;
Liu, Xingping;
Fei, Caifeng;
Huang, Xunbin;
Tang, Yunge;
Zhou, Li-quan

Publication type:

Article

Identification of flexible Pif1–DNA interactions and their impacts on enzymatic activities.

Published in:

Nucleic Acids Research, 2022, v. 50, n. 12, p. 7002, doi. 10.1093/nar/gkac529

By:

Li, Jinghua;
Ma, Jianbing;
Kumar, Vikash;
Fu, Hang;
Xu, Chunhua;
Wang, Shuang;
Jia, Qi;
Fan, Qinkai;
Xi, Xuguang;
Li, Ming;
Liu, Haiguang;
Lu, Ying

Publication type:

Article

HSP90 and Aha1 modulate microRNA maturation through promoting the folding of Dicer1.

Published in:

Nucleic Acids Research, 2022, v. 50, n. 12, p. 6990, doi. 10.1093/nar/gkac528

By:

Liu, Xiaochuan;
Yang, Yen-Yu;
Wang, Yinsheng

Publication type:

Article

Ribodysgenesis: sudden genome instability in the yeast Saccharomyces cerevisiae arising from RNase H2 cleavage at genomic-embedded ribonucleotides.

Published in:

Nucleic Acids Research, 2022, v. 50, n. 12, p. 6890, doi. 10.1093/nar/gkac536

By:

Sui, Yang;
Epstein, Anastasiya;
Dominska, Margaret;
Zheng, Dao-Qiong;
Petes, Thomas D;
Klein, Hannah L

Publication type:

Article

LncRNA OIP5-AS1-directed miR-7 degradation promotes MYMX production during human myogenesis.

Published in:

Nucleic Acids Research, 2022, v. 50, n. 12, p. 7115, doi. 10.1093/nar/gkac524

By:

Yang, Jen-Hao;
Chang, Ming-Wen;
Tsitsipatis, Dimitrios;
Yang, Xiaoling;
Martindale, Jennifer L;
Munk, Rachel;
Cheng, Aiwu;
Izydore, Elizabeth;
Pandey, Poonam R;
Piao, Yulan;
Mazan-Mamczarz, Krystyna;
De, Supriyo;
Abdelmohsen, Kotb;
Gorospe, Myriam

Publication type:

Article

G-quadruplex structure of the C. elegans telomeric repeat: a two tetrads basket type conformation stabilized by a non-canonical C–T base-pair.

Published in:

Nucleic Acids Research, 2022, v. 50, n. 12, p. 7134, doi. 10.1093/nar/gkac523

By:

Marquevielle, Julien;
De Rache, Aurore;
Vialet, Brune;
Morvan, Estelle;
Mergny, Jean-Louis;
Amrane, Samir

Publication type:

Article

Torsional behaviour of supercoiled DNA regulates recognition of architectural protein Fis on minicircle DNA.

Published in:

Nucleic Acids Research, 2022, v. 50, n. 12, p. 6671, doi. 10.1093/nar/gkac522

By:

Mondal, Anupam;
Sangeeta;
Bhattacherjee, Arnab

Publication type:

Article

Migrating bubble synthesis promotes mutagenesis through lesions in its template.

Published in:

Nucleic Acids Research, 2022, v. 50, n. 12, p. 6870, doi. 10.1093/nar/gkac520

By:

Osia, Beth;
Twarowski, Jerzy;
Jackson, Tyler;
Lobachev, Kirill;
Liu, Liping;
Malkova, Anna

Publication type:

Article

Anatomy of four human Argonaute proteins.

Published in:

Nucleic Acids Research, 2022, v. 50, n. 12, p. 6618, doi. 10.1093/nar/gkac519

By:

Nakanishi, Kotaro

Publication type:

Article

Direct tracking of reverse-transcriptase speed and template sensitivity: implications for sequencing and analysis of long RNA molecules.

Published in:

Nucleic Acids Research, 2022, v. 50, n. 12, p. 6980, doi. 10.1093/nar/gkac518

By:

Guo, Li-Tao;
Olson, Sara;
Patel, Shivali;
Graveley, Brenton R;
Pyle, Anna Marie

Publication type:

Article

Host cell RecA activates a mobile element-encoded mutagenic DNA polymerase.

Published in:

Nucleic Acids Research, 2022, v. 50, n. 12, p. 6854, doi. 10.1093/nar/gkac515

By:

Ojha, Debika;
Jaszczur, Malgorzata M;
Sikand, Adhirath;
McDonald, John P;
Robinson, Andrew;
van Oijen, Antoine M;
Mak, Chi H;
Pinaud, Fabien;
Cox, Michael M;
Woodgate, Roger;
Goodman, Myron F

Publication type:

Article

cotranscriptional folding landscape for two cyclic di-nucleotide-sensing riboswitches with highly homologous aptamer domains acting either as ON- or OFF-switches.

Published in:

Nucleic Acids Research, 2022, v. 50, n. 12, p. 6639, doi. 10.1093/nar/gkac514

By:

Landgraf, Tom;
Völklein, Albrecht Eduard;
Fürtig, Boris;
Schwalbe, Harald

Publication type:

Article

Body temperature variation controls pre-mRNA processing and transcription of antiviral genes and SARS-CoV-2 replication.

Published in:

Nucleic Acids Research, 2022, v. 50, n. 12, p. 6769, doi. 10.1093/nar/gkac513

By:

Los, Bruna;
Preußner, Marco;
Eschke, Kathrin;
Vidal, Ricardo Martin;
Abdelgawad, Azza;
Olofsson, Didrik;
Keiper, Sandra;
Paulo-Pedro, Margarida;
Grindel, Alica;
Meinke, Stefan;
Trimpert, Jakob;
Heyd, Florian

Publication type:

Article

TRIM25 inhibits influenza A virus infection, destabilizes viral mRNA, but is redundant for activating the RIG-I pathway.

Published in:

Nucleic Acids Research, 2022, v. 50, n. 12, p. 7097, doi. 10.1093/nar/gkac512

By:

Choudhury, Nila Roy;
Trus, Ivan;
Heikel, Gregory;
Wolczyk, Magdalena;
Szymanski, Jacek;
Bolembach, Agnieszka;
Dos Santos Pinto, Rute Maria;
Smith, Nikki;
Trubitsyna, Maryia;
Gaunt, Eleanor;
Digard, Paul;
Michlewski, Gracjan

Publication type:

Article

Correction to 'Effects of chain length and geometry on the activation of DNA damage bypass by polyubiquitylated PCNA' and 'Structural basis of ubiquitin recognition by the winged-helix domain of Cockayne syndrome group B protein'.

Published in:: Nucleic Acids Research, 2022, v. 50, n. 12, p. 7197, doi. 10.1093/nar/gkac507
Publication type:: Article

Decoding phage resistance by mpr and its role in survivability of Mycobacterium smegmatis.

Published in:

Nucleic Acids Research, 2022, v. 50, n. 12, p. 6938, doi. 10.1093/nar/gkac505

By:

Seniya, Surya Pratap;
Jain, Vikas

Publication type:

Article

Synthesis of the NarP response regulator of nitrate respiration in Escherichia coli is regulated at multiple levels by Hfq and small RNAs.

Published in:

Nucleic Acids Research, 2022, v. 50, n. 12, p. 6753, doi. 10.1093/nar/gkac504

By:

Brosse, Anaïs;
Boudry, Pierre;
Walburger, Anne;
Magalon, Axel;
Guillier, Maude

Publication type:

Article

Tissue- and ethnicity-independent hypervariable DNA methylation states show evidence of establishment in the early human embryo.

Published in:

Nucleic Acids Research, 2022, v. 50, n. 12, p. 6735, doi. 10.1093/nar/gkac503

By:

Derakhshan, Maria;
Kessler, Noah J;
Ishida, Miho;
Demetriou, Charalambos;
Brucato, Nicolas;
Moore, Gudrun E;
Fall, Caroline H D;
Chandak, Giriraj R;
Ricaut, Francois-Xavier;
Prentice, Andrew M;
Hellenthal, Garrett;
Silver, Matt J

Publication type:

Article

new bacterial tRNA enhances antibiotic production in Streptomyces by circumventing inefficient wobble base-pairing.

Published in:

Nucleic Acids Research, 2022, v. 50, n. 12, p. 7084, doi. 10.1093/nar/gkac502

By:

Chen, Ximing;
Li, Shuyan;
Zhang, Binglin;
Sun, Haili;
Wang, Jinxiu;
Zhang, Wei;
Meng, Wenbo;
Chen, Tuo;
Dyson, Paul;
Liu, Guangxiu

Publication type:

Article

AtNusG, a chloroplast nucleoid protein of bacterial origin linking chloroplast transcriptional and translational machineries, is required for proper chloroplast gene expression in Arabidopsis thaliana.

Published in:

Nucleic Acids Research, 2022, v. 50, n. 12, p. 6715, doi. 10.1093/nar/gkac501

By:

Xiong, Hai-Bo;
Pan, Hui-Min;
Long, Qiao-Ying;
Wang, Zi-Yuan;
Qu, Wan-Tong;
Mei, Tong;
Zhang, Nan;
Xu, Xiao-Feng;
Yang, Zhong-Nan;
Yu, Qing-Bo

Publication type:

Article

Drosophila hnRNP F/H homolog Glorund recruits dFMRP to inhibit nanos translation elongation.

Published in:

Nucleic Acids Research, 2022, v. 50, n. 12, p. 7067, doi. 10.1093/nar/gkac500

By:

Peng, Yingshi;
Gavis, Elizabeth R

Publication type:

Article

PUMILIO competes with AUF1 to control DICER1 RNA levels and miRNA processing.

Published in:

Nucleic Acids Research, 2022, v. 50, n. 12, p. 7048, doi. 10.1093/nar/gkac499

By:

Rajasekaran, Swetha;
Khan, Eshan;
Ching, Samuel R;
Khan, Misbah;
Siddiqui, Jalal K;
Gradia, Daniela F;
Lin, Chenyu;
Bouley, Stephanie J;
Mercadante, Dayna L;
Manning, Amity L;
Gerber, André P;
Walker, James A;
Miles, Wayne O

Publication type:

Article

Mechanism of lesion verification by the human XPD helicase in nucleotide excision repair.

Published in:

Nucleic Acids Research, 2022, v. 50, n. 12, p. 6837, doi. 10.1093/nar/gkac496

By:

Fu, Iwen;
Mu, Hong;
Geacintov, Nicholas E;
Broyde, Suse

Publication type:

Article

Experimental paradigms revisited: oxidative stress-induced tRNA fragmentation does not correlate with stress granule formation but is associated with delayed cell death.

Published in:

Nucleic Acids Research, 2022, v. 50, n. 12, p. 6919, doi. 10.1093/nar/gkac495

By:

Sanadgol, Nasim;
König, Lisa;
Drino, Aleksej;
Jovic, Michaela;
Schaefer, Matthias R

Publication type:

Article

Ep300 sequestration to functionally distinct glucocorticoid receptor binding loci underlie rapid gene activation and repression.

Published in:

Nucleic Acids Research, 2022, v. 50, n. 12, p. 6702, doi. 10.1093/nar/gkac488

By:

Portuguez, Avital Sarusi;
Grbesa, Ivana;
Tal, Moran;
Deitch, Rachel;
Raz, Dana;
Kliker, Limor;
Weismann, Ran;
Schwartz, Michal;
Loza, Olga;
Cohen, Leslie;
Marchenkov-Flam, Libi;
Sung, Myong-Hee;
Kaplan, Tommy;
Hakim, Ofir

Publication type:

Article

dsRBP Staufen2 governs RNP assembly of neuronal Argonaute proteins.

Published in:

Nucleic Acids Research, 2022, v. 50, n. 12, p. 7034, doi. 10.1093/nar/gkac487

By:

Ehses, Janina;
Schlegel, Melina;
Schröger, Luise;
Schieweck, Rico;
Derdak, Sophia;
Bilban, Martin;
Bauer, Karl;
Harner, Max;
Kiebler, Michael A

Publication type:

Article

TWIST1 methylation by SETD6 selectively antagonizes LINC-PINT expression in glioma.

Published in:

Nucleic Acids Research, 2022, v. 50, n. 12, p. 6903, doi. 10.1093/nar/gkac485

By:

Admoni-Elisha, Lee;
Elbaz, Tzofit;
Chopra, Anand;
Shapira, Guy;
Bedford, Mark T;
Fry, Christopher J;
Shomron, Noam;
Biggar, Kyle;
Feldman, Michal;
Levy, Dan

Publication type:

Article

Controllable assembly of synthetic constructs with programmable ternary DNA interaction.

Published in:

Nucleic Acids Research, 2022, v. 50, n. 12, p. 7188, doi. 10.1093/nar/gkac478

By:

Cui, Huangchen;
Zhang, Tianqing;
Kong, Yuhan;
Xing, Hang;
Wei, Bryan

Publication type:

Article

Insights into the product release mechanism of dengue virus NS3 helicase.

Published in:

Nucleic Acids Research, 2022, v. 50, n. 12, p. 6968, doi. 10.1093/nar/gkac473

By:

Adler, Natalia S;
Cababie, Leila A;
Sarto, Carolina;
Cavasotto, Claudio N;
Gebhard, Leopoldo G;
Estrin, Darío A;
Gamarnik, Andrea V;
Arrar, Mehrnoosh;
Kaufman, Sergio B

Publication type:

Article

Utilizing RNA origami scaffolds in Saccharomyces cerevisiae for dCas9-mediated transcriptional control.

Published in:

Nucleic Acids Research, 2022, v. 50, n. 12, p. 7176, doi. 10.1093/nar/gkac470

By:

Pothoulakis, Georgios;
Nguyen, Michael T A;
Andersen, Ebbe S

Publication type:

Article

TEB/POLQ plays dual roles in protecting Arabidopsis from NO-induced DNA damage.

Published in:

Nucleic Acids Research, 2022, v. 50, n. 12, p. 6820, doi. 10.1093/nar/gkac469

By:

Lv, Qiang;
Han, Shuang;
Wang, Lei;
Xia, Jinchan;
Li, Peng;
Hu, Ruoyang;
Wang, Jinzheng;
Gao, Lei;
Chen, Yuli;
Wang, Yu;
Du, Jing;
Bao, Fang;
Hu, Yong;
Xu, Xingzhi;
Xiao, Wei;
He, Yikun

Publication type:

Article

Genome-wide CRISPR/Cas9 transcriptional activation screen identifies a histone acetyltransferase inhibitor complex as a regulator of HIV-1 integration.

Published in:

Nucleic Acids Research, 2022, v. 50, n. 12, p. 6687, doi. 10.1093/nar/gkac464

By:

Zhang, Qiong;
Wang, Shaobo;
Li, Wanyu;
Yau, Edwin;
Hui, Hui;
Singh, Parmit Kumar;
Achuthan, Vasudevan;
Young Karris, Maile Ann;
Engelman, Alan N;
Rana, Tariq M

Publication type:

Article

Joint dimension reduction and clustering analysis of single-cell RNA-seq and spatial transcriptomics data.

Published in:

Nucleic Acids Research, 2022, v. 50, n. 12, p. e72, doi. 10.1093/nar/gkac219

By:

Liu, Wei;
Liao, Xu;
Yang, Yi;
Lin, Huazhen;
Yeong, Joe;
Zhou, Xiang;
Shi, Xingjie;
Liu, Jin

Publication type:

Article

MarcoPolo: a method to discover differentially expressed genes in single-cell RNA-seq data without depending on prior clustering.

Published in:

Nucleic Acids Research, 2022, v. 50, n. 12, p. e71, doi. 10.1093/nar/gkac216

By:

Kim, Chanwoo;
Lee, Hanbin;
Jeong, Juhee;
Jung, Keehoon;
Han, Buhm

Publication type:

Article

EPIMUTESTR: a nearest neighbor machine learning approach to predict cancer driver genes from the evolutionary action of coding variants.

Published in:

Nucleic Acids Research, 2022, v. 50, n. 12, p. e70, doi. 10.1093/nar/gkac215

By:

Parvandeh, Saeid;
Donehower, Lawrence A;
Panagiotis, Katsonis;
Hsu, Teng-Kuei;
Asmussen, Jennifer K;
Lee, Kwanghyuk;
Lichtarge, Olivier

Publication type:

Article

Optical control of protein delivery and partitioning in the nucleolus.

Published in:

Nucleic Acids Research, 2022, v. 50, n. 12, p. e69, doi. 10.1093/nar/gkac191

By:

Tan, Peng;
Hong, Tingting;
Cai, Xiaoli;
Li, Wenbo;
Huang, Yun;
He, Lian;
Zhou, Yubin

Publication type:

Article

Stitchr: stitching coding TCR nucleotide sequences from V/J/CDR3 information.

Published in:

Nucleic Acids Research, 2022, v. 50, n. 12, p. e68, doi. 10.1093/nar/gkac190

By:

Heather, James M;
Spindler, Matthew J;
Alonso, Marta Herrero;
Shui, Yifang Ivana;
Millar, David G;
Johnson, David S;
Cobbold, Mark;
Hata, Aaron N

Publication type:

Article

Expanding the DNA-encoded library toolbox: identifying small molecules targeting RNA.

Published in:

Nucleic Acids Research, 2022, v. 50, n. 12, p. e67, doi. 10.1093/nar/gkac173

By:

Chen, Qiuxia;
Li, You;
Lin, Chunrong;
Chen, Liu;
Luo, Hao;
Xia, Shuai;
Liu, Chuan;
Cheng, Xuemin;
Liu, Chengzhong;
Li, Jin;
Dou, Dengfeng

Publication type:

Article

Deficiency of ribosomal proteins reshapes the transcriptional and translational landscape in human cells.

Published in:

Nucleic Acids Research, 2022, v. 50, n. 12, p. 6601, doi. 10.1093/nar/gkac053

By:

Luan, Yizhao;
Tang, Nan;
Yang, Jiaqi;
Liu, Shuting;
Cheng, Chichi;
Wang, Yan;
Chen, Congying;
Guo, Ya-nan;
Wang, Hongwei;
Zhao, Wenxue;
Zhao, Qian;
Li, Wei;
Xiang, Mengqing;
Ju, Rong;
Xie, Zhi

Publication type:

Article