Works matching IS 03051048 AND DT 2022 AND VI 50 AND IP 11

Results: 45

Bi-PE: bi-directional priming improves CRISPR/Cas9 prime editing in mammalian cells.

Published in:

Nucleic Acids Research, 2022, v. 50, n. 11, p. 6423, doi. 10.1093/nar/gkac506

By:

Tao, Rui;
Wang, Yanhong;
Jiao, Yaoge;
Hu, Yun;
Li, Li;
Jiang, Lurong;
Zhou, Lifang;
Qu, Junyan;
Chen, Qiang;
Yao, Shaohua

Publication type:

Article

Inhibition of histone acetyltransferase GCN5 by a transcription factor FgPacC controls fungal adaption to host-derived iron stress.

Published in:

Nucleic Acids Research, 2022, v. 50, n. 11, p. 6190, doi. 10.1093/nar/gkac498

By:

Gu, Qin;
Wang, Yujie;
Zhao, Xiaozhen;
Yuan, Bingqin;
Zhang, Mengxuan;
Tan, Zheng;
Zhang, Xinyue;
Chen, Yun;
Wu, Huijun;
Luo, Yuming;
Keller, Nancy P;
Gao, Xuewen;
Ma, Zhonghua

Publication type:

Article

Expression of Bacillus subtilis ABCF antibiotic resistance factor VmlR is regulated by RNA polymerase pausing, transcription attenuation, translation attenuation and (p)ppGpp.

Published in:

Nucleic Acids Research, 2022, v. 50, n. 11, p. 6174, doi. 10.1093/nar/gkac497

By:

Takada, Hiraku;
Mandell, Zachary F;
Yakhnin, Helen;
Glazyrina, Anastasiya;
Chiba, Shinobu;
Kurata, Tatsuaki;
Wu, Kelvin J Y;
Tresco, Ben I C;
Myers, Andrew G;
Aktinson, Gemma C;
Babitzke, Paul;
Hauryliuk, Vasili

Publication type:

Article

TBX2 acts as a potent transcriptional silencer of tumour suppressor genes through interaction with the CoREST complex to sustain the proliferation of breast cancers.

Published in:

Nucleic Acids Research, 2022, v. 50, n. 11, p. 6154, doi. 10.1093/nar/gkac494

By:

McIntyre, Alexander J;
Angel, Charlotte Z;
Smith, James S;
Templeman, Amy;
Beattie, Katherine;
Beattie, Shannon;
Ormrod, Alice;
Devlin, Eadaoin;
McGreevy, Charles;
Bothwell, Chloe;
Eddie, Sharon L;
Buckley, Niamh E;
Williams, Rich;
Mullan, Paul B

Publication type:

Article

HSFs drive transcription of distinct genes and enhancers during oxidative stress and heat shock.

Published in:

Nucleic Acids Research, 2022, v. 50, n. 11, p. 6102, doi. 10.1093/nar/gkac493

By:

Himanen, Samu V;
Puustinen, Mikael C;
Da Silva, Alejandro J;
Vihervaara, Anniina;
Sistonen, Lea

Publication type:

Article

Insight into RNA–DNA primer length counting by human primosome.

Published in:

Nucleic Acids Research, 2022, v. 50, n. 11, p. 6264, doi. 10.1093/nar/gkac492

By:

Baranovskiy, Andrey G;
Lisova, Alisa E;
Morstadt, Lucia M;
Babayeva, Nigar D;
Tahirov, Tahir H

Publication type:

Article

Noncanonical NF-κB factor p100/p52 regulates homologous recombination and modulates sensitivity to DNA-damaging therapy.

Published in:

Nucleic Acids Research, 2022, v. 50, n. 11, p. 6251, doi. 10.1093/nar/gkac491

By:

Budke, Brian;
Zhong, Alison;
Sullivan, Katherine;
Park, Chanyoung;
Gittin, David I;
Kountz, Timothy S;
Connell, Philip P

Publication type:

Article

Role of aIF5B in archaeal translation initiation.

Published in:

Nucleic Acids Research, 2022, v. 50, n. 11, p. 6532, doi. 10.1093/nar/gkac490

By:

Kazan, Ramy;
Bourgeois, Gabrielle;
Lazennec-Schurdevin, Christine;
Larquet, Eric;
Mechulam, Yves;
Coureux, Pierre-Damien;
Schmitt, Emmanuelle

Publication type:

Article

Schlafen 5 suppresses human immunodeficiency virus type 1 transcription by commandeering cellular epigenetic machinery.

Published in:

Nucleic Acids Research, 2022, v. 50, n. 11, p. 6137, doi. 10.1093/nar/gkac489

By:

Ding, Jiwei;
Wang, Shujie;
Wang, Zhen;
Chen, Shumin;
Zhao, Jianyuan;
Solomon, Magan;
Liu, Zhenlong;
Guo, Fei;
Ma, Ling;
Wen, Jiajia;
Li, Xiaoyu;
Liang, Chen;
Cen, Shan

Publication type:

Article

THO complex deficiency impairs DNA double-strand break repair via the RNA surveillance kinase SMG-1.

Published in:

Nucleic Acids Research, 2022, v. 50, n. 11, p. 6235, doi. 10.1093/nar/gkac472

By:

Kamp, Juliette A;
Lemmens, Bennie B L G;
Romeijn, Ron J;
González-Prieto, Román;
Olsen, Jesper V;
Vertegaal, Alfred C O;
van Schendel, Robin;
Tijsterman, Marcel

Publication type:

Article

Topoisomerase 1 inhibits MYC promoter activity by inducing G-quadruplex formation.

Published in:

Nucleic Acids Research, 2022, v. 50, n. 11, p. 6332, doi. 10.1093/nar/gkac482

By:

Keller, Josephine Geertsen;
Hymøller, Kirstine Mejlstrup;
Thorsager, Maria Eriksen;
Hansen, Noriko Y;
Erlandsen, Jens Uldum;
Tesauro, Cinzia;
Simonsen, Anne Katrine W;
Andersen, Anne Bech;
Vandsø Petersen, Kamilla;
Holm, Lise Lolle;
Stougaard, Magnus;
Andresen, Brage Storstein;
Kristensen, Peter;
Frøhlich, Rikke;
Knudsen, Birgitta R

Publication type:

Article

Towards a comprehensive understanding of RNA deamination: synthesis and properties of xanthosine-modified RNA.

Published in:

Nucleic Acids Research, 2022, v. 50, n. 11, p. 6038, doi. 10.1093/nar/gkac477

By:

Mair, Stefan;
Erharter, Kevin;
Renard, Eva;
Brillet, Karl;
Brunner, Melanie;
Lusser, Alexandra;
Kreutz, Christoph;
Ennifar, Eric;
Micura, Ronald

Publication type:

Article

pathway independent multi-modular ordered control system based on thermosensors and CRISPRi improves bioproduction in Bacillus subtilis.

Published in:

Nucleic Acids Research, 2022, v. 50, n. 11, p. 6587, doi. 10.1093/nar/gkac476

By:

Yu, Wenwen;
Jin, Ke;
Wu, Yaokang;
Zhang, Quanwei;
Liu, Yanfeng;
Li, Jianghua;
Du, Guocheng;
Chen, Jian;
Lv, Xueqin;
Ledesma-Amaro, Rodrigo;
Liu, Long

Publication type:

Article

snoGloBe interaction predictor reveals a broad spectrum of C/D snoRNA RNA targets.

Published in:

Nucleic Acids Research, 2022, v. 50, n. 11, p. 6067, doi. 10.1093/nar/gkac475

By:

Deschamps-Francoeur, Gabrielle;
Couture, Sonia;
Abou-Elela, Sherif;
Scott, Michelle S

Publication type:

Article

ARMC5 is part of an RPB1-specific ubiquitin ligase implicated in adrenal hyperplasia.

Published in:

Nucleic Acids Research, 2022, v. 50, n. 11, p. 6343, doi. 10.1093/nar/gkac483

By:

Lao, Linjiang;
Bourdeau, Isabelle;
Gagliardi, Lucia;
He, Xiao;
Shi, Wei;
Hao, Bingbing;
Tan, Minjia;
Hu, Yan;
Peng, Junzheng;
Coulombe, Benoit;
Torpy, David J;
Scott, Hamish S;
Lacroix, Andre;
Luo, Hongyu;
Wu, Jiangping

Publication type:

Article

KDM6B promotes PARthanatos via suppression of O6-methylguanine DNA methyltransferase repair and sustained checkpoint response.

Published in:

Nucleic Acids Research, 2022, v. 50, n. 11, p. 6313, doi. 10.1093/nar/gkac471

By:

Yang, Mingming;
Wang, Chenliang;
Zhou, Mi;
Bao, Lei;
Wang, Yanan;
Kumar, Ashwani;
Xing, Chao;
Luo, Weibo;
Wang, Yingfei

Publication type:

Article

UG/Abi: a highly diverse family of prokaryotic reverse transcriptases associated with defense functions.

Published in:

Nucleic Acids Research, 2022, v. 50, n. 11, p. 6084, doi. 10.1093/nar/gkac467

By:

Mestre, Mario Rodríguez;
Gao, Linyi Alex;
Shah, Shiraz A;
López-Beltrán, Adrián;
González-Delgado, Alejandro;
Martínez-Abarca, Francisco;
Iranzo, Jaime;
Redrejo-Rodríguez, Modesto;
Zhang, Feng;
Toro, Nicolás

Publication type:

Article

CRISPR-Cas12a targeting of ssDNA plays no detectable role in immunity.

Published in:

Nucleic Acids Research, 2022, v. 50, n. 11, p. 6414, doi. 10.1093/nar/gkac462

By:

Marino, Nicole D;
Pinilla-Redondo, Rafael;
Bondy-Denomy, Joseph

Publication type:

Article

Noncanonical prokaryotic X family DNA polymerases lack polymerase activity and act as exonucleases.

Published in:

Nucleic Acids Research, 2022, v. 50, n. 11, p. 6398, doi. 10.1093/nar/gkac461

By:

Prostova, Maria;
Shilkin, Evgeniy;
Kulikova, Alexandra A;
Makarova, Alena;
Ryazansky, Sergei;
Kulbachinskiy, Andrey

Publication type:

Article

merlin, an improved framework for the reconstruction of high-quality genome-scale metabolic models.

Published in:

Nucleic Acids Research, 2022, v. 50, n. 11, p. 6052, doi. 10.1093/nar/gkac459

By:

Capela, João;
Lagoa, Davide;
Rodrigues, Ruben;
Cunha, Emanuel;
Cruz, Fernando;
Barbosa, Ana;
Bastos, José;
Lima, Diogo;
Ferreira, Eugénio C;
Rocha, Miguel;
Dias, Oscar

Publication type:

Article

in-library ligation strategy and its application in CRISPR/Cas9 screening of high-order gRNA combinations.

Published in:

Nucleic Acids Research, 2022, v. 50, n. 11, p. 6575, doi. 10.1093/nar/gkac458

By:

Lu, Zhike;
Ni, Ke;
Wang, Yingying;
Zhou, Yangfan;
Li, Yini;
Yan, Jianfeng;
Song, Qingkai;
Liu, Min;
Xu, Yujun;
Yu, Zhenxing;
Guo, Tiannan;
Ma, Lijia

Publication type:

Article

40S hnRNP particles are a novel class of nuclear biomolecular condensates.

Published in:

Nucleic Acids Research, 2022, v. 50, n. 11, p. 6300, doi. 10.1093/nar/gkac457

By:

Domanski, Michal;
Dedic, Emil;
Pérez, Maria Escura;
Cléry, Antoine;
Campagne, Sébastien;
Uldry, Anne-Christine;
Braga, Sophie;
Heller, Manfred;
Rabl, Julius;
Afanasyev, Pavel;
Boehringer, Daniel;
Nováček, Jiří;
Allain, Frédéric T;
Mühlemann, Oliver

Publication type:

Article

Considerations and recommendations for assessment of plasma protein binding and drug–drug interactions for siRNA therapeutics.

Published in:

Nucleic Acids Research, 2022, v. 50, n. 11, p. 6020, doi. 10.1093/nar/gkac456

By:

Humphreys, Sara C;
Davis, John A;
Iqbal, Sajida;
Kamel, Amin;
Kulmatycki, Kenneth;
Lao, Yanbin;
Liu, Xiumin;
Rodgers, John;
Snoeys, Jan;
Vigil, Adam;
Weng, Yan;
Wiethoff, Christopher M;
Wittwer, Matthias B

Publication type:

Article

Structural basis for interaction between CLAMP and MSL2 proteins involved in the specific recruitment of the dosage compensation complex in Drosophila.

Published in:

Nucleic Acids Research, 2022, v. 50, n. 11, p. 6521, doi. 10.1093/nar/gkac455

By:

Tikhonova, Evgeniya;
Mariasina, Sofia;
Efimov, Sergey;
Polshakov, Vladimir;
Maksimenko, Oksana;
Georgiev, Pavel;
Bonchuk, Artem

Publication type:

Article

Binding of the transcription activator-like effector augments transcriptional regulation by another transcription factor.

Published in:

Nucleic Acids Research, 2022, v. 50, n. 11, p. 6562, doi. 10.1093/nar/gkac454

By:

Leben, Katja;
Strmšek, Žiga;
Lebar, Tina;
Verbič, Anže;
Dragovan, Matej;
Omersa, Neža;
Anderluh, Gregor;
Jerala, Roman

Publication type:

Article

Allosteric couplings upon binding of RfaH to transcription elongation complexes.

Published in:

Nucleic Acids Research, 2022, v. 50, n. 11, p. 6384, doi. 10.1093/nar/gkac453

By:

Molina, José Alejandro;
Galaz-Davison, Pablo;
Komives, Elizabeth A;
Artsimovitch, Irina;
Ramírez-Sarmiento, César A

Publication type:

Article

Phosphorylation-dependent association of human chromatin protein PC4 to linker histone H1 regulates genome organization and transcription.

Published in:

Nucleic Acids Research, 2022, v. 50, n. 11, p. 6116, doi. 10.1093/nar/gkac450

By:

Mustafi, Pallabi;
Hu, Mingli;
Kumari, Sujata;
Das, Chandrima;
Li, Guohong;
Kundu, Tapas K

Publication type:

Article

Enhanced nucleosome assembly at CpG sites containing an extended 5-methylcytosine analogue.

Published in:

Nucleic Acids Research, 2022, v. 50, n. 11, p. 6549, doi. 10.1093/nar/gkac444

By:

Tomkuvienė, Miglė;
Meier, Markus;
Ikasalaitė, Diana;
Wildenauer, Julia;
Kairys, Visvaldas;
Klimašauskas, Saulius;
Manelytė, Laura

Publication type:

Article

Allosteric regulation of noncoding RNA function by microRNAs.

Published in:

Nucleic Acids Research, 2022, v. 50, n. 11, p. 6511, doi. 10.1093/nar/gkac443

By:

Gorbea, Carlos;
Elhakiem, Abdalla;
Cazalla, Demián

Publication type:

Article

domains of yeast eIF4G, eIF4E and the cap fine-tune eIF4A activities through an intricate network of stimulatory and inhibitory effects.

Published in:

Nucleic Acids Research, 2022, v. 50, n. 11, p. 6497, doi. 10.1093/nar/gkac437

By:

Krause, Linda;
Willing, Florian;
Andreou, Alexandra Zoi;
Klostermeier, Dagmar

Publication type:

Article

MutL binds to 3′ resected DNA ends and blocks DNA polymerase access.

Published in:

Nucleic Acids Research, 2022, v. 50, n. 11, p. 6224, doi. 10.1093/nar/gkac432

By:

Borsellini, Alessandro;
Lebbink, Joyce H G;
Lamers, Meindert H

Publication type:

Article

Xer activation factor of TLCΦ expands the possibilities for Xer recombination.

Published in:

Nucleic Acids Research, 2022, v. 50, n. 11, p. 6368, doi. 10.1093/nar/gkac429

By:

Miele, Solange;
Provan, James Iain;
Vergne, Justine;
Possoz, Christophe;
Ochsenbein, Françoise;
Barre, François-Xavier

Publication type:

Article

HNRNPH1 destabilizes the G-quadruplex structures formed by G-rich RNA sequences that regulate the alternative splicing of an oncogenic fusion transcript.

Published in:

Nucleic Acids Research, 2022, v. 50, n. 11, p. 6474, doi. 10.1093/nar/gkac409

By:

Vo, Tam;
Brownmiller, Tayvia;
Hall, Katherine;
Jones, Tamara L;
Choudhari, Sulbha;
Grammatikakis, Ioannis;
Ludwig, Katelyn R;
Caplen, Natasha J

Publication type:

Article

Probing small ribosomal subunit RNA helix 45 acetylation across eukaryotic evolution.

Published in:

Nucleic Acids Research, 2022, v. 50, n. 11, p. 6284, doi. 10.1093/nar/gkac404

By:

Bortolin-Cavaillé, Marie-Line;
Quillien, Aurélie;
Thalalla Gamage, Supuni;
Thomas, Justin M;
Sas-Chen, Aldema;
Sharma, Sunny;
Plisson-Chastang, Célia;
Vandel, Laurence;
Blader, Patrick;
Lafontaine, Denis L J;
Schwartz, Schraga;
Meier, Jordan L;
Cavaillé, Jérôme

Publication type:

Article

Vectorial folding of telomere overhang promotes higher accessibility.

Published in:

Nucleic Acids Research, 2022, v. 50, n. 11, p. 6271, doi. 10.1093/nar/gkac401

By:

Paul, Tapas;
Opresko, Patricia L;
Ha, Taekjip;
Myong, Sua

Publication type:

Article

Ribosomal protein eL39 is important for maturation of the nascent polypeptide exit tunnel and proper protein folding during translation.

Published in:

Nucleic Acids Research, 2022, v. 50, n. 11, p. 6453, doi. 10.1093/nar/gkac366

By:

Micic, Jelena;
Rodríguez-Galán, Olga;
Babiano, Reyes;
Fitzgerald, Fiona;
Fernández-Fernández, José;
Zhang, Yunyang;
Gao, Ning;
Woolford, John L;
de la Cruz, Jesús

Publication type:

Article

Comprehensive analysis of PNA-based antisense antibiotics targeting various essential genes in uropathogenic Escherichia coli.

Published in:

Nucleic Acids Research, 2022, v. 50, n. 11, p. 6435, doi. 10.1093/nar/gkac362

By:

Popella, Linda;
Jung, Jakob;
Do, Phuong Thao;
Hayward, Regan J;
Barquist, Lars;
Vogel, Jörg

Publication type:

Article

SCAPE: a mixture model revealing single-cell polyadenylation diversity and cellular dynamics during cell differentiation and reprogramming.

Published in:

Nucleic Acids Research, 2022, v. 50, n. 11, p. e66, doi. 10.1093/nar/gkac167

By:

Zhou, Ran;
Xiao, Xia;
He, Ping;
Zhao, Yuancun;
Xu, Mengying;
Zheng, Xiuran;
Yang, Ruirui;
Chen, Shasha;
Zhou, Lifang;
Zhang, Dan;
Yang, Qingxin;
Song, Junwei;
Tang, Chao;
Zhang, Yiming;
Lin, Jing-wen;
Cheng, Lu;
Chen, Lu

Publication type:

Article

CRISPR/Cas13 effectors have differing extents of off-target effects that limit their utility in eukaryotic cells.

Published in:

Nucleic Acids Research, 2022, v. 50, n. 11, p. e65, doi. 10.1093/nar/gkac159

By:

Ai, Yuxi;
Liang, Dongming;
Wilusz, Jeremy E

Publication type:

Article

TransposonUltimate: software for transposon classification, annotation and detection.

Published in:

Nucleic Acids Research, 2022, v. 50, n. 11, p. e64, doi. 10.1093/nar/gkac136

By:

Riehl, Kevin;
Riccio, Cristian;
Miska, Eric A;
Hemberg, Martin

Publication type:

Article

Single-cell genome-wide concurrent haplotyping and copy-number profiling through genotyping-by-sequencing.

Published in:

Nucleic Acids Research, 2022, v. 50, n. 11, p. e63, doi. 10.1093/nar/gkac134

By:

Masset, Heleen;
Ding, Jia;
Dimitriadou, Eftychia;
Debrock, Sophie;
Tšuiko, Olga;
Smits, Katrien;
Peeraer, Karen;
Voet, Thierry;
Zamani Esteki, Masoud;
Vermeesch, Joris R

Publication type:

Article

Ligation-assisted homologous recombination enables precise genome editing by deploying both MMEJ and HDR.

Published in:

Nucleic Acids Research, 2022, v. 50, n. 11, p. e62, doi. 10.1093/nar/gkac118

By:

Zhao, Zhihan;
Shang, Peng;
Sage, Fanny;
Geijsen, Niels

Publication type:

Article

ALT-FISH quantifies alternative lengthening of telomeres activity by imaging of single-stranded repeats.

Published in:

Nucleic Acids Research, 2022, v. 50, n. 11, p. e61, doi. 10.1093/nar/gkac113

By:

Frank, Lukas;
Rademacher, Anne;
Mücke, Norbert;
Tirier, Stephan M;
Koeleman, Emma;
Knotz, Caroline;
Schumacher, Sabrina;
Stainczyk, Sabine A;
Westermann, Frank;
Fröhling, Stefan;
Chudasama, Priya;
Rippe, Karsten

Publication type:

Article

Protoplast fusion in Bacillus species produces frequent, unbiased, genome-wide homologous recombination.

Published in:

Nucleic Acids Research, 2022, v. 50, n. 11, p. 6211, doi. 10.1093/nar/gkac025

By:

Vasileva, Delyana P;
Streich, Jared C;
Burdick, Leah H;
Klingeman, Dawn M;
Chhetri, Hari B;
Brelsford, Christa M;
Ellis, J Christopher;
Close, Dan M;
Jacobson, Daniel A;
Michener, Joshua K

Publication type:

Article

Tissue-specific regulation of translational readthrough tunes functions of the traffic jam transcription factor.

Published in:

Nucleic Acids Research, 2022, v. 50, n. 11, p. 6001, doi. 10.1093/nar/gkab1189

By:

Karki, Prajwal;
Carney, Travis D;
Maracci, Cristina;
Yatsenko, Andriy S;
Shcherbata, Halyna R;
Rodnina, Marina V

Publication type:

Article