Works matching IS 03051048 AND DT 2021 AND VI 49 AND IP 5

Results: 47

Conserved dual-mode gene regulation programs in higher eukaryotes.

Published in:

Nucleic Acids Research, 2021, v. 49, n. 5, p. 2583, doi. 10.1093/nar/gkab108

By:

Lee, Jun-Yeong;
Song, Jawon;
LeBlanc, Lucy;
Davis, Ian;
Kim, Jonghwan;
Beck, Samuel

Publication type:

Article

Role of CxxC-finger protein 1 in establishing mouse oocyte epigenetic landscapes.

Published in:

Nucleic Acids Research, 2021, v. 49, n. 5, p. 2569, doi. 10.1093/nar/gkab107

By:

Sha, Qian-Qian;
Zhu, Ye-Zhang;
Xiang, Yunlong;
Yu, Jia-Li;
Fan, Xiao-Ying;
Li, Yan-Chu;
Wu, Yun-Wen;
Shen, Li;
Fan, Heng-Yu

Publication type:

Article

Mechanisms of spacer acquisition by sequential assembly of the adaptation module in Synechocystis.

Published in:

Nucleic Acids Research, 2021, v. 49, n. 5, p. 2973, doi. 10.1093/nar/gkab105

By:

Wu, Chengyong;
Tang, Dongmei;
Cheng, Jie;
Hu, Daojun;
Yang, Zejing;
Ma, Xue;
He, Haihuai;
Yao, Shaohua;
Fu, Tian-Min;
Yu, Yamei;
Chen, Qiang

Publication type:

Article

The human tRNA taurine modification enzyme GTPBP3 is an active GTPase linked to mitochondrial diseases.

Published in:

Nucleic Acids Research, 2021, v. 49, n. 5, p. 2816, doi. 10.1093/nar/gkab104

By:

Peng, Gui-Xin;
Zhang, Yong;
Wang, Qin-Qin;
Li, Qing-Run;
Xu, Hong;
Wang, En-Duo;
Zhou, Xiao-Long

Publication type:

Article

Reprograming of sRNA target specificity by the leader peptide peTrpL in response to antibiotic exposure.

Published in:

Nucleic Acids Research, 2021, v. 49, n. 5, p. 2894, doi. 10.1093/nar/gkab093

By:

Melior, Hendrik;
Li, Siqi;
Stötzel, Maximilian;
Maaß, Sandra;
Schütz, Rubina;
Azarderakhsh, Saina;
Shevkoplias, Aleksei;
Barth-Weber, Susanne;
Baumgardt, Kathrin;
Ziebuhr, John;
Förstner, Konrad U;
Chervontseva, Zoe;
Becher, Dörte;
Evguenieva-Hackenberg, Elena

Publication type:

Article

Four-pronged negative feedback of DSB machinery in meiotic DNA-break control in mice.

Published in:

Nucleic Acids Research, 2021, v. 49, n. 5, p. 2609, doi. 10.1093/nar/gkab082

By:

Dereli, Ihsan;
Stanzione, Marcello;
Olmeda, Fabrizio;
Papanikos, Frantzeskos;
Baumann, Marek;
Demir, Sevgican;
Carofiglio, Fabrizia;
Lange, Julian;
de Massy, Bernard;
Baarends, Willy M;
Turner, James;
Rulands, Steffen;
Tóth, Attila

Publication type:

Article

Hsp70 acts as a fine-switch that controls E3 ligase CHIP-mediated TAp63 and ΔNp63 ubiquitination and degradation.

Published in:

Nucleic Acids Research, 2021, v. 49, n. 5, p. 2740, doi. 10.1093/nar/gkab081

By:

Wu, H Helena;
Wang, Benfan;
Armstrong, Stephen R;
Abuetabh, Yasser;
Leng, Sarah;
Roa, Wilson H Y;
Atfi, Azeddine;
Marchese, Adriano;
Wilson, Beverly;
Sergi, Consolato;
Flores, Elsa R;
Eisenstat, David D;
Leng, Roger P

Publication type:

Article

Molecular insights into miRNA processing by Arabidopsis thaliana SERRATE.

Published in:: Nucleic Acids Research, 2021, v. 49, n. 5, p. 3002, doi. 10.1093/nar/gkab103
Publication type:: Article

Tandem RNA binding sites induce self-association of the stress granule marker protein TIA-1.

Published in:

Nucleic Acids Research, 2021, v. 49, n. 5, p. 2403, doi. 10.1093/nar/gkab080

By:

Loughlin, Fionna E;
West, Danella L;
Gunzburg, Menachem J;
Waris, Saboora;
Crawford, Simon A;
Wilce, Matthew C J;
Wilce, Jacqueline A

Publication type:

Article

Sequence-independent RNA sensing and DNA targeting by a split domain CRISPR–Cas12a gRNA switch.

Published in:

Nucleic Acids Research, 2021, v. 49, n. 5, p. 2985, doi. 10.1093/nar/gkab100

By:

Collins, Scott P;
Rostain, William;
Liao, Chunyu;
Beisel, Chase L

Publication type:

Article

Intron exon boundary junctions in human genome have in-built unique structural and energetic signals.

Published in:

Nucleic Acids Research, 2021, v. 49, n. 5, p. 2674, doi. 10.1093/nar/gkab098

By:

Mishra, Akhilesh;
Siwach, Priyanka;
Misra, Pallavi;
Dhiman, Simran;
Pandey, Ashutosh Kumar;
Srivastava, Parul;
Jayaram, B

Publication type:

Article

Single bacterial resolvases first exploit, then constrain intrinsic dynamics of the Holliday junction to direct recombination.

Published in:

Nucleic Acids Research, 2021, v. 49, n. 5, p. 2803, doi. 10.1093/nar/gkab096

By:

Ray, Sujay;
Pal, Nibedita;
Walter, Nils G

Publication type:

Article

In vivo structure of the Ty1 retrotransposon RNA genome.

Published in:

Nucleic Acids Research, 2021, v. 49, n. 5, p. 2878, doi. 10.1093/nar/gkab090

By:

Andrzejewska, Angelika;
Zawadzka, Małgorzata;
Gumna, Julita;
Garfinkel, David J;
Pachulska-Wieczorek, Katarzyna

Publication type:

Article

Dynamics of Ku and bacterial non-homologous end-joining characterized using single DNA molecule analysis.

Published in:

Nucleic Acids Research, 2021, v. 49, n. 5, p. 2629, doi. 10.1093/nar/gkab083

By:

Öz, Robin;
Wang, Jing L;
Guerois, Raphael;
Goyal, Gaurav;
KK, Sriram;
Ropars, Virginie;
Sharma, Rajhans;
Koca, Firat;
Charbonnier, Jean-Baptiste;
Modesti, Mauro;
Strick, Terence R;
Westerlund, Fredrik

Publication type:

Article

DAZAP2 acts as specifier of the p53 response to DNA damage.

Published in:

Nucleic Acids Research, 2021, v. 49, n. 5, p. 2759, doi. 10.1093/nar/gkab084

By:

Liebl, Magdalena C;
Moehlenbrink, Jutta;
Becker, Huong;
Raddatz, Günter;
Abdeen, Suhaib K;
Aqeilan, Rami I;
Lyko, Frank;
Hofmann, Thomas G

Publication type:

Article

Current and emerging roles of Cockayne syndrome group B (CSB) protein.

Published in:

Nucleic Acids Research, 2021, v. 49, n. 5, p. 2418, doi. 10.1093/nar/gkab085

By:

Tiwari, Vinod;
Baptiste, Beverly A;
Okur, Mustafa N;
Bohr, Vilhelm A

Publication type:

Article

Binding of phosphorothioate oligonucleotides with RNase H1 can cause conformational changes in the protein and alter the interactions of RNase H1 with other proteins.

Published in:

Nucleic Acids Research, 2021, v. 49, n. 5, p. 2721, doi. 10.1093/nar/gkab078

By:

Zhang, Lingdi;
Vickers, Timothy A;
Sun, Hong;
Liang, Xue-hai;
Crooke, Stanley T

Publication type:

Article

Structural mechanism of DNA recognition by the p204 HIN domain.

Published in:

Nucleic Acids Research, 2021, v. 49, n. 5, p. 2959, doi. 10.1093/nar/gkab076

By:

Fan, Xiaojiao;
Jiang, Jiansheng;
Zhao, Dan;
Chen, Feng;
Ma, Huan;
Smith, Patrick;
Unterholzner, Leonie;
Xiao, Tsan Sam;
Jin, Tengchuan

Publication type:

Article

Structural basis for RNA recognition by the N-terminal tandem RRM domains of human RBM45.

Published in:

Nucleic Acids Research, 2021, v. 49, n. 5, p. 2946, doi. 10.1093/nar/gkab075

By:

Chen, Xiaolei;
Yang, Zhongmei;
Wang, Wenfeng;
Qian, Kaiyue;
Liu, Mingjie;
Wang, Junchao;
Wang, Mingzhu

Publication type:

Article

RNA polymerase clamp conformational dynamics: long-lived states and modulation by crowding, cations, and nonspecific DNA binding.

Published in:

Nucleic Acids Research, 2021, v. 49, n. 5, p. 2790, doi. 10.1093/nar/gkab074

By:

Mazumder, Abhishek;
Wang, Anna;
Uhm, Heesoo;
Ebright, Richard H;
Kapanidis, Achillefs N

Publication type:

Article

The CRISPR ancillary effector Can2 is a dual-specificity nuclease potentiating type III CRISPR defence.

Published in:

Nucleic Acids Research, 2021, v. 49, n. 5, p. 2777, doi. 10.1093/nar/gkab073

By:

Zhu, Wenlong;
McQuarrie, Stuart;
Grüschow, Sabine;
McMahon, Stephen A;
Graham, Shirley;
Gloster, Tracey M;
White, Malcolm F

Publication type:

Article

The SR-protein Npl3 is an essential component of the meiotic splicing regulatory network in Saccharomyces cerevisiae.

Published in:

Nucleic Acids Research, 2021, v. 49, n. 5, p. 2552, doi. 10.1093/nar/gkab071

By:

Sandhu, Rima;
Sinha, Aniketa;
Montpetit, Ben

Publication type:

Article

DHX29 reduces leaky scanning through an upstream AUG codon regardless of its nucleotide context.

Published in:: Nucleic Acids Research, 2021, v. 49, n. 5, p. 3001, doi. 10.1093/nar/gkab069
Publication type:: Article

eIF5 and eIF5B together stimulate 48S initiation complex formation during ribosomal scanning.

Published in:: Nucleic Acids Research, 2021, v. 49, n. 5, p. 3000, doi. 10.1093/nar/gkab068
Publication type:: Article

SUMOylation of YTHDF2 promotes mRNA degradation and cancer progression by increasing its binding affinity with m6A-modified mRNAs.

Published in:

Nucleic Acids Research, 2021, v. 49, n. 5, p. 2859, doi. 10.1093/nar/gkab065

By:

Hou, Guofang;
Zhao, Xian;
Li, Lian;
Yang, Qianqian;
Liu, Xiaojia;
Huang, Caihu;
Lu, Runhui;
Chen, Ran;
Wang, Yanli;
Jiang, Bin;
Yu, Jianxiu

Publication type:

Article

Bacteria have numerous distinctive groups of phage–plasmids with conserved phage and variable plasmid gene repertoires.

Published in:

Nucleic Acids Research, 2021, v. 49, n. 5, p. 2655, doi. 10.1093/nar/gkab064

By:

Pfeifer, Eugen;
Sousa, Jorge A Moura de;
Touchon, Marie;
Rocha, Eduardo P C

Publication type:

Article

Interplay of folded domains and the disordered low-complexity domain in mediating hnRNPA1 phase separation.

Published in:

Nucleic Acids Research, 2021, v. 49, n. 5, p. 2931, doi. 10.1093/nar/gkab063

By:

Martin, Erik W;
Thomasen, F Emil;
Milkovic, Nicole M;
Cuneo, Matthew J;
Grace, Christy R;
Nourse, Amanda;
Lindorff-Larsen, Kresten;
Mittag, Tanja

Publication type:

Article

HuB and HuD repress telomerase activity by dissociating HuR from TERC.

Published in:

Nucleic Acids Research, 2021, v. 49, n. 5, p. 2848, doi. 10.1093/nar/gkab062

By:

Cheng, Xiaolei;
Gu, Xiaoping;
Xia, Tianjiao;
Ma, Zhengliang;
Yang, Zhongzhou;
Feng, Helen Lechen;
Zhao, Yong;
Ma, Wenbin;
Ju, Zhenyu;
Gorospe, Myriam;
Yi, Xia;
Tang, Hao;
Wang, Wengong

Publication type:

Article

Hamster PIWI proteins bind to piRNAs with stage-specific size variations during oocyte maturation.

Published in:

Nucleic Acids Research, 2021, v. 49, n. 5, p. 2700, doi. 10.1093/nar/gkab059

By:

Ishino, Kyoko;
Hasuwa, Hidetoshi;
Yoshimura, Jun;
Iwasaki, Yuka W;
Nishihara, Hidenori;
Seki, Naomi M;
Hirano, Takamasa;
Tsuchiya, Marie;
Ishizaki, Hinako;
Masuda, Harumi;
Kuramoto, Tae;
Saito, Kuniaki;
Sakakibara, Yasubumi;
Toyoda, Atsushi;
Itoh, Takehiko;
Siomi, Mikiko C;
Morishita, Shinichi;
Siomi, Haruhiko

Publication type:

Article

A critical role for linker DNA in higher-order folding of chromatin fibers.

Published in:

Nucleic Acids Research, 2021, v. 49, n. 5, p. 2537, doi. 10.1093/nar/gkab058

By:

Brouwer, Thomas;
Pham, Chi;
Kaczmarczyk, Artur;
de Voogd, Willem-Jan;
Botto, Margherita;
Vizjak, Petra;
Mueller-Planitz, Felix;
van Noort, John

Publication type:

Article

Novel roles of an intragenic G-quadruplex in controlling microRNA expression and cardiac function.

Published in:

Nucleic Acids Research, 2021, v. 49, n. 5, p. 2522, doi. 10.1093/nar/gkab055

By:

Zhu, Min;
Gao, Juan;
Lin, Xian-Juan;
Gong, Yun-Yun;
Qi, Yan-Chao;
Ma, Yuan-Liang;
Song, Yuan-Xiu;
Tan, Wei;
Li, Fang-Yuan;
Ye, Min;
Gong, Jun;
Cui, Qing-Hua;
Huang, Zeng-Hui;
Zhang, You-Yi;
Wang, Xiu-Jie;
Lan, Feng;
Wang, Shi-Qiang;
Yuan, Gu;
Feng, Yue;
Xu, Ming

Publication type:

Article

Aberrant splicing in neuroblastoma generates RNA-fusion transcripts and provides vulnerability to spliceosome inhibitors.

Published in:

Nucleic Acids Research, 2021, v. 49, n. 5, p. 2509, doi. 10.1093/nar/gkab054

By:

Shi, Yao;
Yuan, Juan;
Rraklli, Vilma;
Maxymovitz, Eva;
Cipullo, Miriam;
Liu, Mingzhi;
Li, Shuijie;
Westerlund, Isabelle;
Bedoya-Reina, Oscar C;
Bullova, Petra;
Rorbach, Joanna;
Juhlin, C Christofer;
Stenman, Adam;
Larsson, Catharina;
Kogner, Per;
O'Sullivan, Maureen J;
Schlisio, Susanne;
Holmberg, Johan

Publication type:

Article

Fra-1 regulates its target genes via binding to remote enhancers without exerting major control on chromatin architecture in triple negative breast cancers.

Published in:

Nucleic Acids Research, 2021, v. 49, n. 5, p. 2488, doi. 10.1093/nar/gkab053

By:

Bejjani, Fabienne;
Tolza, Claire;
Boulanger, Mathias;
Downes, Damien;
Romero, Raphaël;
Maqbool, Muhammad Ahmad;
Zine El Aabidine, Amal;
Andrau, Jean-Christophe;
Lebre, Sophie;
Brehelin, Laurent;
Parrinello, Hughes;
Rohmer, Marine;
Kaoma, Tony;
Vallar, Laurent;
Hughes, Jim R;
Zibara, Kazem;
Lecellier, Charles-Henri;
Piechaczyk, Marc;
Jariel-Encontre, Isabelle

Publication type:

Article

SAMHD1 restrains aberrant nucleotide insertions at repair junctions generated by DNA end joining.

Published in:

Nucleic Acids Research, 2021, v. 49, n. 5, p. 2598, doi. 10.1093/nar/gkab051

By:

Akimova, Ekaterina;
Gassner, Franz Josef;
Schubert, Maria;
Rebhandl, Stefan;
Arzt, Claudia;
Rauscher, Stefanie;
Tober, Vanessa;
Zaborsky, Nadja;
Greil, Richard;
Geisberger, Roland

Publication type:

Article

siRNAs containing 2′-fluorinated Northern-methanocarbacyclic (2′-F-NMC) nucleotides: in vitro and in vivo RNAi activity and inability of mitochondrial polymerases to incorporate 2′-F-NMC NTPs.

Published in:

Nucleic Acids Research, 2021, v. 49, n. 5, p. 2435, doi. 10.1093/nar/gkab050

By:

Akabane-Nakata, Masaaki;
Erande, Namrata D;
Kumar, Pawan;
Degaonkar, Rohan;
Gilbert, Jason A;
Qin, June;
Mendez, Martha;
Woods, Lauren Blair;
Jiang, Yongfeng;
Janas, Maja M;
O'Flaherty, Derek K;
Zlatev, Ivan;
Schlegel, Mark K;
Matsuda, Shigeo;
Egli, Martin;
Manoharan, Muthiah

Publication type:

Article

The integrity of the U12 snRNA 3′ stem–loop is necessary for its overall stability.

Published in:

Nucleic Acids Research, 2021, v. 49, n. 5, p. 2835, doi. 10.1093/nar/gkab048

By:

Norppa, Antto J;
Frilander, Mikko J

Publication type:

Article

Restriction of an intron size en route to endothermy.

Published in:

Nucleic Acids Research, 2021, v. 49, n. 5, p. 2460, doi. 10.1093/nar/gkab046

By:

Královičová, Jana;
Borovská, Ivana;
Pengelly, Reuben;
Lee, Eunice;
Abaffy, Pavel;
Šindelka, Radek;
Grutzner, Frank;
Vořechovský, Igor

Publication type:

Article

Reversible chromatin condensation by the DNA repair and demethylation factor thymine DNA glycosylase.

Published in:

Nucleic Acids Research, 2021, v. 49, n. 5, p. 2450, doi. 10.1093/nar/gkab040

By:

Deckard, Charles E;
Sczepanski, Jonathan T

Publication type:

Article

Application of counter-selectable marker PIGA in engineering designer deletion cell lines and characterization of CRISPR deletion efficiency.

Published in:

Nucleic Acids Research, 2021, v. 49, n. 5, p. 2642, doi. 10.1093/nar/gkab035

By:

Li, Donghui;
Sun, Xiaoji;
Yu, Fangzhou;
Perle, Mary Ann;
Araten, David;
Boeke, Jef D

Publication type:

Article

N6-Methyladenosines in mRNAs reduce the accuracy of codon reading by transfer RNAs and peptide release factors.

Published in:

Nucleic Acids Research, 2021, v. 49, n. 5, p. 2684, doi. 10.1093/nar/gkab033

By:

Ieong, Ka-Weng;
Indrisiunaite, Gabriele;
Prabhakar, Arjun;
Puglisi, Joseph D;
Ehrenberg, Måns

Publication type:

Article

A high-throughput screening method for evolving a demethylase enzyme with improved and new functionalities.

Published in:

Nucleic Acids Research, 2021, v. 49, n. 5, p. e30, doi. 10.1093/nar/gkaa1213

By:

Wang, Yuru;
Katanski, Christopher D;
Watkins, Christopher;
Pan, Jessica N;
Dai, Qing;
Jiang, Zhuoxun;
Pan, Tao

Publication type:

Article

Optogenetic control of Neisseria meningitidis Cas9 genome editing using an engineered, light-switchable anti-CRISPR protein.

Published in:

Nucleic Acids Research, 2021, v. 49, n. 5, p. e29, doi. 10.1093/nar/gkaa1198

By:

Hoffmann, Mareike D;
Mathony, Jan;
Upmeier zu Belzen, Julius;
Harteveld, Zander;
Aschenbrenner, Sabine;
Stengl, Christina;
Grimm, Dirk;
Correia, Bruno E;
Eils, Roland;
Niopek, Dominik

Publication type:

Article

FAX-RIC enables robust profiling of dynamic RNP complex formation in multicellular organisms in vivo.

Published in:

Nucleic Acids Research, 2021, v. 49, n. 5, p. e28, doi. 10.1093/nar/gkaa1194

By:

Na, Yongwoo;
Kim, Hyunjoon;
Choi, Yeon;
Shin, Sanghee;
Jung, Jae Hun;
Kwon, S Chul;
Kim, V Narry;
Kim, Jong-Seo

Publication type:

Article

Nucleotide resolution profiling of m3C RNA modification by HAC-seq.

Published in:

Nucleic Acids Research, 2021, v. 49, n. 5, p. e27, doi. 10.1093/nar/gkaa1186

By:

Cui, Jia;
Liu, Qi;
Sendinc, Erdem;
Shi, Yang;
Gregory, Richard I

Publication type:

Article

Smart-ORF: a single-molecule method for accessing ribosome dynamics in both upstream and main open reading frames.

Published in:

Nucleic Acids Research, 2021, v. 49, n. 5, p. e26, doi. 10.1093/nar/gkaa1185

By:

Gaba, Anthony;
Wang, Hongyun;
Fortune, Trinisia;
Qu, Xiaohui

Publication type:

Article

A suppressor tRNA-mediated feedforward loop eliminates leaky gene expression in bacteria.

Published in:

Nucleic Acids Research, 2021, v. 49, n. 5, p. e25, doi. 10.1093/nar/gkaa1179

By:

Ho, Joanne M L;
Miller, Corwin A;
Parks, Sydney E;
Mattia, Jacob R;
Bennett, Matthew R

Publication type:

Article

Structural and dynamical insights into the PH domain of p62 in human TFIIH.

Published in:

Nucleic Acids Research, 2021, v. 49, n. 5, p. 2916, doi. 10.1093/nar/gkaa1045

By:

Okuda, Masahiko;
Ekimoto, Toru;
Kurita, Jun-ichi;
Ikeguchi, Mitsunori;
Nishimura, Yoshifumi

Publication type:

Article