Works matching IS 03051048 AND DT 2021 AND VI 49 AND IP 14

Results: 48

Genetic vulnerabilities upon inhibition of DNA damage response.

Published in:

Nucleic Acids Research, 2021, v. 49, n. 14, p. 8214, doi. 10.1093/nar/gkab643

By:

Wang, Chao;
Tang, Mengfan;
Chen, Zhen;
Nie, Litong;
Li, Siting;
Xiong, Yun;
Szymonowicz, Klaudia Anna;
Park, Jeong-Min;
Zhang, Huimin;
Feng, Xu;
Huang, Min;
Su, Dan;
Hart, Traver;
Chen, Junjie

Publication type:

Article

Core promoter activity contributes to chromatin-based regulation of internal cryptic promoters.

Published in:

Nucleic Acids Research, 2021, v. 49, n. 14, p. 8097, doi. 10.1093/nar/gkab639

By:

Lee, Bo Bae;
Woo, Hyeonju;
Lee, Min Kyung;
Youn, SeoJung;
Lee, Sumin;
Roe, Jae-Seok;
Lee, Soo Young;
Kim, TaeSoo

Publication type:

Article

Correction to 'Expression of mRNA electroporated into plant and animal cells'.

Published in:

Nucleic Acids Research, 2021, v. 49, n. 14, p. 8406, doi. 10.1093/nar/gkab636

By:

Callis, J;
Fromm, M;
Walbot, V

Publication type:

Article

Motif WFYY of human PrimPol is crucial to stabilize the incoming 3′-nucleotide during replication fork restart.

Published in:

Nucleic Acids Research, 2021, v. 49, n. 14, p. 8199, doi. 10.1093/nar/gkab634

By:

Calvo, Patricia A;
Martínez-Jiménez, María I;
Díaz, Marcos;
Stojkovic, Gorazd;
Kasho, Kazutoshi;
Guerra, Susana;
Wanrooij, Sjoerd;
Méndez, Juan;
Blanco, Luis

Publication type:

Article

Characterization of a functional endothelial super-enhancer that regulates ADAMTS18 and angiogenesis.

Published in:

Nucleic Acids Research, 2021, v. 49, n. 14, p. 8078, doi. 10.1093/nar/gkab633

By:

Mushimiyimana, Isidore;
Niskanen, Henri;
Beter, Mustafa;
Laakkonen, Johanna P;
Kaikkonen, Minna U;
Ylä-Herttuala, Seppo;
Laham-Karam, Nihay

Publication type:

Article

The clinical importance of tandem exon duplication-derived substitutions.

Published in:

Nucleic Acids Research, 2021, v. 49, n. 14, p. 8232, doi. 10.1093/nar/gkab623

By:

Martinez Gomez, Laura;
Pozo, Fernando;
Walsh, Thomas A;
Abascal, Federico;
Tress, Michael L

Publication type:

Article

Discovering single nucleotide variants and indels from bulk and single-cell ATAC-seq.

Published in:

Nucleic Acids Research, 2021, v. 49, n. 14, p. 7986, doi. 10.1093/nar/gkab621

By:

Massarat, Arya R;
Sen, Arko;
Jaureguy, Jeff;
Tyndale, Sélène T;
Fu, Yi;
Erikson, Galina;
McVicker, Graham

Publication type:

Article

The RGG domain in the C-terminus of the DEAD box helicases Dbp2 and Ded1 is necessary for G-quadruplex destabilization.

Published in:

Nucleic Acids Research, 2021, v. 49, n. 14, p. 8339, doi. 10.1093/nar/gkab620

By:

Yan, Kevin Kok-Phen;
Obi, Ikenna;
Sabouri, Nasim

Publication type:

Article

The Bromodomains of the mammalian SWI/SNF (mSWI/SNF) ATPases Brahma (BRM) and Brahma Related Gene 1 (BRG1) promote chromatin interaction and are critical for skeletal muscle differentiation.

Published in:

Nucleic Acids Research, 2021, v. 49, n. 14, p. 8060, doi. 10.1093/nar/gkab617

By:

Sharma, Tapan;
Robinson, Daniel C L;
Witwicka, Hanna;
Dilworth, F Jeffrey;
Imbalzano, Anthony N

Publication type:

Article

Predicting stability of DNA bulge at mononucleotide microsatellite.

Published in:

Nucleic Acids Research, 2021, v. 49, n. 14, p. 7901, doi. 10.1093/nar/gkab616

By:

Bae, Jin H;
Zhang, David Yu

Publication type:

Article

Pyrophosphate release acts as a kinetic checkpoint during high-fidelity DNA replication by the Staphylococcus aureus replicative polymerase PolC.

Published in:

Nucleic Acids Research, 2021, v. 49, n. 14, p. 8324, doi. 10.1093/nar/gkab613

By:

Fagan, Sean P;
Mukherjee, Purba;
Jaremko, William J;
Nelson-Rigg, Rachel;
Wilson, Ryan C;
Dangerfield, Tyler L;
Johnson, Kenneth A;
Lahiri, Indrajit;
Pata, Janice D

Publication type:

Article

Structural and biochemical insight into the mechanism of dual CpG site binding and methylation by the DNMT3A DNA methyltransferase.

Published in:

Nucleic Acids Research, 2021, v. 49, n. 14, p. 8294, doi. 10.1093/nar/gkab600

By:

Emperle, Max;
Bangalore, Disha M;
Adam, Sabrina;
Kunert, Stefan;
Heil, Hannah S;
Heinze, Katrin G;
Bashtrykov, Pavel;
Tessmer, Ingrid;
Jeltsch, Albert

Publication type:

Article

Stabilization and structural changes of 2D DNA origami by enzymatic ligation.

Published in:

Nucleic Acids Research, 2021, v. 49, n. 14, p. 7884, doi. 10.1093/nar/gkab611

By:

Rajendran, Arivazhagan;
Krishnamurthy, Kirankumar;
Giridasappa, Amulya;
Nakata, Eiji;
Morii, Takashi

Publication type:

Article

HBO1 is a versatile histone acyltransferase critical for promoter histone acylations.

Published in:

Nucleic Acids Research, 2021, v. 49, n. 14, p. 8037, doi. 10.1093/nar/gkab607

By:

Xiao, Yanhui;
Li, Wenjing;
Yang, Hui;
Pan, Lulu;
Zhang, Liwei;
Lu, Lu;
Chen, Jiwei;
Wei, Wei;
Ye, Jie;
Li, Jiwen;
Li, Guohong;
Zhang, Yong;
Tan, Minjia;
Ding, Jianping;
Wong, Jiemin

Publication type:

Article

RBFOX2 alters splicing outcome in distinct binding modes with multiple protein partners.

Published in:

Nucleic Acids Research, 2021, v. 49, n. 14, p. 8370, doi. 10.1093/nar/gkab595

By:

Zhou, Delong;
Couture, Sonia;
Scott, Michelle S;
Abou Elela, Sherif

Publication type:

Article

Mutually exclusive substrate selection strategy by human m<sup>3</sup>C RNA transferases METTL2A and METTL6.

Published in:

Nucleic Acids Research, 2021, v. 49, n. 14, p. 8309, doi. 10.1093/nar/gkab603

By:

Mao, Xue-Ling;
Li, Zi-Han;
Huang, Meng-Han;
Wang, Jin-Tao;
Zhou, Jing-Bo;
Li, Qing-Run;
Xu, Hong;
Wang, Xi-Jin;
Zhou, Xiao-Long

Publication type:

Article

Photorhabdus antibacterial Rhs polymorphic toxin inhibits translation through ADP-ribosylation of 23S ribosomal RNA.

Published in:

Nucleic Acids Research, 2021, v. 49, n. 14, p. 8384, doi. 10.1093/nar/gkab608

By:

Jurėnas, Dukas;
Payelleville, Amaury;
Roghanian, Mohammad;
Turnbull, Kathryn J;
Givaudan, Alain;
Brillard, Julien;
Hauryliuk, Vasili;
Cascales, Eric

Publication type:

Article

Guanidine-II aptamer conformations and ligand binding modes through the lens of molecular simulation.

Published in:

Nucleic Acids Research, 2021, v. 49, n. 14, p. 7954, doi. 10.1093/nar/gkab592

By:

Steuer, Jakob;
Kukharenko, Oleksandra;
Riedmiller, Kai;
Hartig, Jörg S;
Peter, Christine

Publication type:

Article

ANANSE: an enhancer network-based computational approach for predicting key transcription factors in cell fate determination.

Published in:

Nucleic Acids Research, 2021, v. 49, n. 14, p. 7966, doi. 10.1093/nar/gkab598

By:

Xu, Quan;
Georgiou, Georgios;
Frölich, Siebren;
van der Sande, Maarten;
Veenstra, Gert Jan C;
Zhou, Huiqing;
van Heeringen, Simon J

Publication type:

Article

Plasmid replication based on the T7 origin of replication requires a T7 RNAP variant and inactivation of ribonuclease H.

Published in:

Nucleic Acids Research, 2021, v. 49, n. 14, p. 8189, doi. 10.1093/nar/gkab596

By:

Becker, Katja;
Meyer, Andreas;
Roberts, Tania Michelle;
Panke, Sven

Publication type:

Article

Recognition of single-stranded nucleic acids by small-molecule splicing modulators.

Published in:

Nucleic Acids Research, 2021, v. 49, n. 14, p. 7870, doi. 10.1093/nar/gkab602

By:

Tang, Zhichao;
Akhter, Sana;
Ramprasad, Ankita;
Wang, Xiao;
Reibarkh, Mikhail;
Wang, Jinan;
Aryal, Sadikshya;
Thota, Srinivas S;
Zhao, Junxing;
Douglas, Justin T;
Gao, Philip;
Holmstrom, Erik D;
Miao, Yinglong;
Wang, Jingxin

Publication type:

Article

Targeting a noncanonical, hairpin-containing G-quadruplex structure from the MYCN gene.

Published in:

Nucleic Acids Research, 2021, v. 49, n. 14, p. 7856, doi. 10.1093/nar/gkab594

By:

Yang, Mo;
Carter, Sakereh;
Parmar, Shaifaly;
Bume, Desta D;
Calabrese, David R;
Liang, Xiao;
Yazdani, Kamyar;
Xu, Man;
Liu, Zhihui;
Thiele, Carol J;
Schneekloth, John S

Publication type:

Article

Golgi-58K can re-localize to late endosomes upon cellular uptake of PS-ASOs and facilitates endosomal release of ASOs.

Published in:

Nucleic Acids Research, 2021, v. 49, n. 14, p. 8277, doi. 10.1093/nar/gkab599

By:

Liang, Xue-Hai;
Nichols, Joshua G;
De Hoyos, Cheryl Li;
Sun, Hong;
Zhang, Lingdi;
Crooke, Stanley T

Publication type:

Article

RqcH and RqcP catalyze processive poly-alanine synthesis in a reconstituted ribosome-associated quality control system.

Published in:

Nucleic Acids Research, 2021, v. 49, n. 14, p. 8355, doi. 10.1093/nar/gkab589

By:

Takada, Hiraku;
Crowe-McAuliffe, Caillan;
Polte, Christine;
Sidorova, Zhanna Yu;
Murina, Victoriia;
Atkinson, Gemma C;
Konevega, Andrey L;
Ignatova, Zoya;
Wilson, Daniel N;
Hauryliuk, Vasili

Publication type:

Article

Single molecule analysis indicates stimulation of MUTYH by UV-DDB through enzyme turnover.

Published in:

Nucleic Acids Research, 2021, v. 49, n. 14, p. 8177, doi. 10.1093/nar/gkab591

By:

Jang, Sunbok;
Schaich, Matthew A;
Khuu, Cindy;
Schnable, Brittani L;
Majumdar, Chandrima;
Watkins, Simon C;
David, Sheila S;
Van Houten, Bennett

Publication type:

Article

LSH catalyzes ATP-driven exchange of histone variants macroH2A1 and macroH2A2.

Published in:

Nucleic Acids Research, 2021, v. 49, n. 14, p. 8024, doi. 10.1093/nar/gkab588

By:

Ni, Kai;
Muegge, Kathrin

Publication type:

Article

Local states of chromatin compaction at transcription start sites control transcription levels.

Published in:

Nucleic Acids Research, 2021, v. 49, n. 14, p. 8007, doi. 10.1093/nar/gkab587

By:

Ishihara, Satoru;
Sasagawa, Yohei;
Kameda, Takeru;
Yamashita, Hayato;
Umeda, Mana;
Kotomura, Naoe;
Abe, Masayuki;
Shimono, Yohei;
Nikaido, Itoshi

Publication type:

Article

RNAi and Ino80 complex control rate limiting translocation step that moves rDNA to eroding telomeres.

Published in:

Nucleic Acids Research, 2021, v. 49, n. 14, p. 8161, doi. 10.1093/nar/gkab586

By:

Apte, Manasi S;
Masuda, Hirohisa;
Wheeler, David Lee;
Cooper, Julia Promisel

Publication type:

Article

The conserved Tpk1 regulates non-homologous end joining double-strand break repair by phosphorylation of Nej1, a homolog of the human XLF.

Published in:

Nucleic Acids Research, 2021, v. 49, n. 14, p. 8145, doi. 10.1093/nar/gkab585

By:

Jessulat, Matthew;
Amin, Shahreen;
Hooshyar, Mohsen;
Malty, Ramy;
Moutaoufik, Mohamed Taha;
Zilocchi, Mara;
Istace, Zoe;
Phanse, Sadhna;
Aoki, Hiroyuki;
Omidi, Katayoun;
Burnside, Daniel;
Samanfar, Bahram;
Aly, Khaled A;
Golshani, Ashkan;
Babu, Mohan

Publication type:

Article

Coupling of the engineered DNA "mutator" to a biosensor as a new paradigm for activation of silent biosynthetic gene clusters in Streptomyces.

Published in:

Nucleic Acids Research, 2021, v. 49, n. 14, p. 8396, doi. 10.1093/nar/gkab583

By:

Sekurova, Olga N;
Sun, Yi-Qian;
Zehl, Martin;
Rückert, Christian;
Stich, Anna;
Busche, Tobias;
Kalinowski, Jörn;
Zotchev, Sergey B

Publication type:

Article

Inferring single cell expression profiles from overlapped pooling sequencing data with compressed sensing strategy.

Published in:

Nucleic Acids Research, 2021, v. 49, n. 14, p. 7995, doi. 10.1093/nar/gkab581

By:

Huang, Mengting;
Yang, Yixuan;
Wen, Xingzhao;
Xu, Weiqiang;
Lu, Na;
Sun, Xiao;
Tu, Jing;
Lu, Zuhong

Publication type:

Article

Roles of non-canonical structures of nucleic acids in cancer and neurodegenerative diseases.

Published in:

Nucleic Acids Research, 2021, v. 49, n. 14, p. 7839, doi. 10.1093/nar/gkab580

By:

Tateishi-Karimata, Hisae;
Sugimoto, Naoki

Publication type:

Article

Translation mediated by the nuclear cap-binding complex is confined to the perinuclear region via a CTIF–DDX19B interaction.

Published in:

Nucleic Acids Research, 2021, v. 49, n. 14, p. 8261, doi. 10.1093/nar/gkab579

By:

Park, Yeonkyoung;
Park, Joori;
Hwang, Hyun Jung;
Kim, Leehyeon;
Jeong, Kwon;
Song, Hyun Kyu;
Rufener, Simone C;
Mühlemann, Oliver;
Kim, Yoon Ki

Publication type:

Article

Cognate restriction of transposition by piggyBac-like proteins.

Published in:

Nucleic Acids Research, 2021, v. 49, n. 14, p. 8135, doi. 10.1093/nar/gkab578

By:

Beckermann, Thomas M;
Luo, Wentian;
Wilson, Catherine M;
Veach, Ruth Ann;
Wilson, Matthew H

Publication type:

Article

Differential efficacies of Cas nucleases on microsatellites involved in human disorders and associated off-target mutations.

Published in:

Nucleic Acids Research, 2021, v. 49, n. 14, p. 8120, doi. 10.1093/nar/gkab569

By:

Poggi, Lucie;
Emmenegger, Lisa;
Descorps-Declère, Stéphane;
Dumas, Bruno;
Richard, Guy-Franck

Publication type:

Article

Preferential import of queuosine-modified tRNAs into Trypanosoma brucei mitochondrion is critical for organellar protein synthesis.

Published in:

Nucleic Acids Research, 2021, v. 49, n. 14, p. 8247, doi. 10.1093/nar/gkab567

By:

Kulkarni, Sneha;
Rubio, Mary Anne T;
Hegedűsová, Eva;
Ross, Robert L;
Limbach, Patrick A;
Alfonzo, Juan D;
Paris, Zdeněk

Publication type:

Article

Towards a global investigation of transcriptomic signatures through co-expression networks and pathway knowledge for the identification of disease mechanisms.

Published in:

Nucleic Acids Research, 2021, v. 49, n. 14, p. 7939, doi. 10.1093/nar/gkab556

By:

Figueiredo, Rebeca Queiroz;
Raschka, Tamara;
Kodamullil, Alpha Tom;
Hofmann-Apitius, Martin;
Mubeen, Sarah;
Domingo-Fernández, Daniel

Publication type:

Article

RoboCOP: jointly computing chromatin occupancy profiles for numerous factors from chromatin accessibility data.

Published in:

Nucleic Acids Research, 2021, v. 49, n. 14, p. 7925, doi. 10.1093/nar/gkab553

By:

Mitra, Sneha;
Zhong, Jianling;
Tran, Trung Q;
MacAlpine, David M;
Hartemink, Alexander J

Publication type:

Article

CTCF as a regulator of alternative splicing: new tricks for an old player.

Published in:

Nucleic Acids Research, 2021, v. 49, n. 14, p. 7825, doi. 10.1093/nar/gkab520

By:

Alharbi, Adel B;
Schmitz, Ulf;
Bailey, Charles G;
Rasko, John E J

Publication type:

Article

Bound2Learn: a machine learning approach for classification of DNA-bound proteins from single-molecule tracking experiments.

Published in:

Nucleic Acids Research, 2021, v. 49, n. 14, p. e79, doi. 10.1093/nar/gkab186

By:

Kapadia, Nitin;
El-Hajj, Ziad W;
Reyes-Lamothe, Rodrigo

Publication type:

Article

Reweighting of molecular simulations with explicit-solvent SAXS restraints elucidates ion-dependent RNA ensembles.

Published in:

Nucleic Acids Research, 2021, v. 49, n. 14, p. e84, doi. 10.1093/nar/gkab459

By:

Bernetti, Mattia;
Hall, Kathleen B;
Bussi, Giovanni

Publication type:

Article

The cooperative assembly of shelterin bridge provides a kinetic gateway that controls telomere length homeostasis.

Published in:

Nucleic Acids Research, 2021, v. 49, n. 14, p. 8110, doi. 10.1093/nar/gkab550

By:

Liu, Jinqiang;
Hu, Xichan;
Bao, Kehan;
Kim, Jin-Kwang;
Zhang, Catherine;
Jia, Songtao;
Qiao, Feng

Publication type:

Article

PseudoGA: cell pseudotime reconstruction based on genetic algorithm.

Published in:

Nucleic Acids Research, 2021, v. 49, n. 14, p. 7909, doi. 10.1093/nar/gkab457

By:

Mondal, Pronoy Kanti;
Saha, Udit Surya;
Mukhopadhyay, Indranil

Publication type:

Article

noisyR: enhancing biological signal in sequencing datasets by characterizing random technical noise.

Published in:

Nucleic Acids Research, 2021, v. 49, n. 14, p. e83, doi. 10.1093/nar/gkab433

By:

Moutsopoulos, Ilias;
Maischak, Lukas;
Lauzikaite, Elze;
Vasquez Urbina, Sergio A;
Williams, Eleanor C;
Drost, Hajk-Georg;
Mohorianu, Irina I

Publication type:

Article

Multiplexed single-cell profiling of chromatin states at genomic loci by expansion microscopy.

Published in:

Nucleic Acids Research, 2021, v. 49, n. 14, p. e82, doi. 10.1093/nar/gkab423

By:

Woodworth, Marcus A;
Ng, Kenneth K H;
Halpern, Aaron R;
Pease, Nicholas A;
Nguyen, Phuc H B;
Kueh, Hao Yuan;
Vaughan, Joshua C

Publication type:

Article

Long-read whole-genome methylation patterning using enzymatic base conversion and nanopore sequencing.

Published in:

Nucleic Acids Research, 2021, v. 49, n. 14, p. e81, doi. 10.1093/nar/gkab397

By:

Sakamoto, Yoshitaka;
Zaha, Suzuko;
Nagasawa, Satoi;
Miyake, Shuhei;
Kojima, Yasuyuki;
Suzuki, Ayako;
Suzuki, Yutaka;
Seki, Masahide

Publication type:

Article

Integrating multiple references for single-cell assignment.

Published in:

Nucleic Acids Research, 2021, v. 49, n. 14, p. e80, doi. 10.1093/nar/gkab380

By:

Duan, Bin;
Chen, Shaoqi;
Chen, Xiaohan;
Zhu, Chenyu;
Tang, Chen;
Wang, Shuguang;
Gao, Yicheng;
Fu, Shaliu;
Liu, Qi

Publication type:

Article

Crucial role of Salmonella genomic island 1 master activator in the parasitism of IncC plasmids.

Published in:

Nucleic Acids Research, 2021, v. 49, n. 14, p. 7807, doi. 10.1093/nar/gkab204

By:

Durand, Romain;
Huguet, Kévin T;
Rivard, Nicolas;
Carraro, Nicolas;
Rodrigue, Sébastien;
Burrus, Vincent

Publication type:

Article