Works matching IS 03051048 AND DT 2020 AND VI 48 AND IP 9

Results: 38

Enabling large-scale genome editing at repetitive elements by reducing DNA nicking.

Published in:

Nucleic Acids Research, 2020, v. 48, n. 9, p. 5183, doi. 10.1093/nar/gkaa239

By:

Smith, Cory J.;
Castanon, Oscar;
Said, Khaled;
Volf, Verena;
Khoshakhlagh, Parastoo;
Hornick, Amanda;
Ferreira, Raphael;
Chun-Ting Wu;
Güell, Marc;
Garg, Shilpa;
Ng, Alex H.M.;
Myllykallio, Hannu;
Church, George M.

Publication type:

Article

Determinants of cyclization–decyclization kinetics of short DNA with sticky ends

Published in:

Nucleic Acids Research, 2020, v. 48, n. 9, p. 5147, doi. 10.1093/nar/gkaa207

By:

Jiyoun Jeong;
Kim, Harold D.

Publication type:

Article

Mutagenesis mechanism of the major oxidative adenine lesion 7,8-dihydro-8-oxoadenine

Published in:

Nucleic Acids Research, 2020, v. 48, n. 9, p. 5119, doi. 10.1093/nar/gkaa193

By:

Myong-Chul Koag;
Hunmin Jung;
Seongmin Lee

Publication type:

Article

Functional organization of box C/D RNA-guided RNA methyltransferase.

Published in:

Nucleic Acids Research, 2020, v. 48, n. 9, p. 5094, doi. 10.1093/nar/gkaa247

By:

Zuxiao Yang;
Jiayin Wang;
Lin Huang;
Lilley, David M.J.;
Keqiong Ye

Publication type:

Article

The flavivirus polymerase NS5 regulates translation of viral genomic RNA

Published in:

Nucleic Acids Research, 2020, v. 48, n. 9, p. 5081, doi. 10.1093/nar/gkaa242

By:

Fajardo Jr., Teodoro;
Sanford, Thomas J.;
Mears, Harriet V.;
Jasper, Annika;
Storrie, Skye;
Mansur, Daniel S.;
Sweeney, Trevor R.

Publication type:

Article

Systematic in vitro profiling of off-target affinity, cleavage and efficiency for CRISPR enzymes

Published in:

Nucleic Acids Research, 2020, v. 48, n. 9, p. 5037, doi. 10.1093/nar/gkaa231

By:

Liyang Zhang;
Rube, H. Tomas;
Vakulskas, Christopher A.;
Behlke, Mark A.;
Bussemaker, Harmen J.;
Pufall, Miles A.

Publication type:

Article

Understanding the paradoxical mechanical response of in-phase A-tracts at different force regimes.

Published in:

Nucleic Acids Research, 2020, v. 48, n. 9, p. 5024, doi. 10.1093/nar/gkaa225

By:

Marin-Gonzalez, Alberto;
Pastrana, Cesar L.;
Bocanegra, Rebeca;
Martín-González, Alejandro;
Vilhena, J.G.;
Pérez, Rubén;
Ibarra, Borja;
Aicart-Ramos, Clara;
Moreno-Herrero, Fernando

Publication type:

Article

Deacetylation enhances ParB–DNA interactions affecting chromosome segregation in Streptomyces coelicolor

Published in:

Nucleic Acids Research, 2020, v. 48, n. 9, p. 4902, doi. 10.1093/nar/gkaa245

By:

Peng Li;
Hong Zhang;
Guo-Ping Zhao;
Wei Zhao

Publication type:

Article

A non-canonical promoter element drives spurious transcription of horizontally acquired bacterial genes.

Published in:

Nucleic Acids Research, 2020, v. 48, n. 9, p. 4891, doi. 10.1093/nar/gkaa244

By:

Warman, Emily A.;
Singh, Shivani S.;
Gubieda, Alicia G.;
Grainger, David C.

Publication type:

Article

Stress-induced lncRNA LASTR fosters cancer cell fitness by regulating the activity of the U4/U6 recycling factor SART3.

Published in:

Nucleic Acids Research, 2020, v. 48, n. 9, p. 5198, doi. 10.1093/nar/gkaa280

By:

Troyer, Linde De;
Zhao, Peihua;
Pastor, Tibor;
Baietti, Maria Francesca;
Barra, Jasmine;
Vendramin, Roberto;
Dok, Ruveyda;
Lechat, Benoit;
Najm, Paul;
Haver, Delphi Van;
Impens, Francis;
Leucci, Eleonora;
Sablina, Anna A

Publication type:

Article

Mammalian RAD51 paralogs protect nascent DNA at stalled forks and mediate replication restart.

Published in:

Nucleic Acids Research, 2020, v. 48, n. 9, p. 5196, doi. 10.1093/nar/gkaa279

By:

Somyajit, Kumar;
Saxena, Sneha;
Babu, Sharath;
Mishra, Anup;
Nagaraju, Ganesh

Publication type:

Article

Weak interactions in higher-order chromatin organization.

Published in:

Nucleic Acids Research, 2020, v. 48, n. 9, p. 4614, doi. 10.1093/nar/gkaa261

By:

Kantidze, Omar L;
Razin, Sergey V

Publication type:

Article

Plasticity of nuclear and cytoplasmic stress responses of RNA-binding proteins.

Published in:

Nucleic Acids Research, 2020, v. 48, n. 9, p. 4725, doi. 10.1093/nar/gkaa256

By:

Backlund, Michael;
Stein, Frank;
Rettel, Mandy;
Schwarzl, Thomas;
Perez-Perri, Joel I;
Brosig, Annika;
Zhou, Yang;
Neu-Yilik, Gabriele;
Hentze, Matthias W;
Kulozik, Andreas E

Publication type:

Article

ATAD5 deficiency alters DNA damage metabolism and sensitizes cells to PARP inhibition.

Published in:

Nucleic Acids Research, 2020, v. 48, n. 9, p. 4928, doi. 10.1093/nar/gkaa255

By:

Giovannini, Sara;
Weller, Marie-Christine;
Hanzlíková, Hana;
Shiota, Tetsuya;
Takeda, Shunichi;
Jiricny, Josef

Publication type:

Article

Specific histone modifications associate with alternative exon selection during mammalian development.

Published in:

Nucleic Acids Research, 2020, v. 48, n. 9, p. 4709, doi. 10.1093/nar/gkaa248

By:

Hu, Qiwen;
Greene, Casey S;
Heller, Elizabeth A

Publication type:

Article

Release of promoter–proximal paused Pol II in response to histone deacetylase inhibition.

Published in:

Nucleic Acids Research, 2020, v. 48, n. 9, p. 4877, doi. 10.1093/nar/gkaa234

By:

Vaid, Roshan;
Wen, Jiayu;
Mannervik, Mattias

Publication type:

Article

Delivery of oligonucleotides to bone marrow to modulate ferrochelatase splicing in a mouse model of erythropoietic protoporphyria.

Published in:

Nucleic Acids Research, 2020, v. 48, n. 9, p. 4658, doi. 10.1093/nar/gkaa229

By:

Halloy, François;
Iyer, Pavithra S;
Ćwiek, Paulina;
Ghidini, Alice;
Barman-Aksözen, Jasmin;
Wildner-Verhey van Wijk, Nicole;
Theocharides, Alexandre P A;
Minder, Elisabeth I;
Schneider-Yin, Xiaoye;
Schümperli, Daniel;
Hall, Jonathan

Publication type:

Article

Biochemical evidence for Ku-independent backup pathways of NHEJ.

Published in:

Nucleic Acids Research, 2020, v. 48, n. 9, p. 5200, doi. 10.1093/nar/gkaa228

By:

Wang, Huichen;
Perrault, Ange Ronel;
Takeda, Yoshihiko;
Qin, Wei;
Wang, Hongyan;
Iliakis, George

Publication type:

Article

Loci specific epigenetic drug sensitivity.

Published in:

Nucleic Acids Research, 2020, v. 48, n. 9, p. 4797, doi. 10.1093/nar/gkaa210

By:

Zhang, Thanutra;
Pilko, Anna;
Wollman, Roy

Publication type:

Article

Machine learning predicts new anti-CRISPR proteins.

Published in:

Nucleic Acids Research, 2020, v. 48, n. 9, p. 4698, doi. 10.1093/nar/gkaa219

By:

Eitzinger, Simon;
Asif, Amina;
Watters, Kyle E;
Iavarone, Anthony T;
Knott, Gavin J;
Doudna, Jennifer A;
Minhas, Fayyaz ul Amir Afsar

Publication type:

Article

Deacetylase-independent function of SIRT6 couples GATA4 transcription factor and epigenetic activation against cardiomyocyte apoptosis.

Published in:

Nucleic Acids Research, 2020, v. 48, n. 9, p. 4992, doi. 10.1093/nar/gkaa214

By:

Peng, Linyuan;
Qian, Minxian;
Liu, Zuojun;
Tang, Xiaolong;
Sun, Jie;
Jiang, Yue;
Sun, Shimin;
Cao, Xinyue;
Pang, Qiuxiang;
Liu, Baohua

Publication type:

Article

Nono deficiency compromises TET1 chromatin association and impedes neuronal differentiation of mouse embryonic stem cells.

Published in:

Nucleic Acids Research, 2020, v. 48, n. 9, p. 4827, doi. 10.1093/nar/gkaa213

By:

Li, Wenjing;
Karwacki-Neisius, Violetta;
Ma, Chun;
Tan, Li;
Shi, Yang;
Wu, Feizhen;
Shi, Yujiang Geno

Publication type:

Article

Genetic interactions and transcriptomics implicate fission yeast CTD prolyl isomerase Pin1 as an agent of RNA 3′ processing and transcription termination that functions via its effects on CTD phosphatase Ssu72.

Published in:

Nucleic Acids Research, 2020, v. 48, n. 9, p. 4811, doi. 10.1093/nar/gkaa212

By:

Sanchez, Ana M;
Garg, Angad;
Shuman, Stewart;
Schwer, Beate

Publication type:

Article

Effect of 2′-5′/3′-5′ phosphodiester linkage heterogeneity on RNA interference.

Published in:

Nucleic Acids Research, 2020, v. 48, n. 9, p. 4643, doi. 10.1093/nar/gkaa222

By:

Habibian, Maryam;
Harikrishna, S;
Fakhoury, Johans;
Barton, Maria;
Ageely, Eman A;
Cencic, Regina;
Fakih, Hassan H;
Katolik, Adam;
Takahashi, Mayumi;
Rossi, John;
Pelletier, Jerry;
Gagnon, Keith T;
Pradeepkumar, P I;
Damha, Masad J

Publication type:

Article

Uncovering the cellular capacity for intensive and specific feedback self-control of the argonautes and MicroRNA targeting activity.

Published in:

Nucleic Acids Research, 2020, v. 48, n. 9, p. 4681, doi. 10.1093/nar/gkaa209

By:

Wang, Degeng;
Wang, Tingzeng;
Gill, Audrey;
Hilliard, Terrell;
Chen, Fengqian;
Karamyshev, Andrey L;
Zhang, Fangyuan

Publication type:

Article

Inverted duplicate DNA sequences increase translocation rates through sequencing nanopores resulting in reduced base calling accuracy.

Published in:

Nucleic Acids Research, 2020, v. 48, n. 9, p. 4940, doi. 10.1093/nar/gkaa206

By:

Spealman, Pieter;
Burrell, Jaden;
Gresham, David

Publication type:

Article

PHB regulates meiotic recombination via JAK2-mediated histone modifications in spermatogenesis.

Published in:

Nucleic Acids Research, 2020, v. 48, n. 9, p. 4780, doi. 10.1093/nar/gkaa203

By:

Zhang, Ling-Fei;
Tan-Tai, Wen-Jing;
Li, Xiao-Hui;
Liu, Mo-Fang;
Shi, Hui-Juan;
Martin-DeLeon, Patricia A;
O, Wai-Sum;
Chen, Hong

Publication type:

Article

EXO1 resection at G-quadruplex structures facilitates resolution and replication.

Published in:

Nucleic Acids Research, 2020, v. 48, n. 9, p. 4960, doi. 10.1093/nar/gkaa199

By:

Stroik, Susanna;
Kurtz, Kevin;
Lin, Kevin;
Karachenets, Sergey;
Myers, Chad L;
Bielinsky, Anja-Katrin;
Hendrickson, Eric A

Publication type:

Article

Molecular architecture of the DNA-binding sites of the P-loop ATPases MipZ and ParA from Caulobacter crescentus.

Published in:

Nucleic Acids Research, 2020, v. 48, n. 9, p. 4769, doi. 10.1093/nar/gkaa192

By:

Corrales-Guerrero, Laura;
He, Binbin;
Refes, Yacine;
Panis, Gaël;
Bange, Gert;
Viollier, Patrick H;
Steinchen, Wieland;
Thanbichler, Martin

Publication type:

Article

Molecular basis of the multifaceted functions of human leucyl-tRNA synthetase in protein synthesis and beyond.

Published in:

Nucleic Acids Research, 2020, v. 48, n. 9, p. 4946, doi. 10.1093/nar/gkaa189

By:

Liu, Ru-Juan;
Long, Tao;
Li, Hao;
Zhao, JingHua;
Li, Jing;
Wang, MingZhu;
Palencia, Andrés;
Lin, JinZhong;
Cusack, Stephen;
Wang, En-Duo

Publication type:

Article

Selective targeting of mutually exclusive DNA G-quadruplexes: HIV-1 LTR as paradigmatic model.

Published in:

Nucleic Acids Research, 2020, v. 48, n. 9, p. 4627, doi. 10.1093/nar/gkaa186

By:

Tassinari, Martina;
Zuffo, Michela;
Nadai, Matteo;
Pirota, Valentina;
Sevilla Montalvo, Adriana Carolina;
Doria, Filippo;
Freccero, Mauro;
Richter, Sara N

Publication type:

Article

Cancer-specific mutation of GATA3 disrupts the transcriptional regulatory network governed by Estrogen Receptor alpha, FOXA1 and GATA3.

Published in:

Nucleic Acids Research, 2020, v. 48, n. 9, p. 4756, doi. 10.1093/nar/gkaa179

By:

Takaku, Motoki;
Grimm, Sara A;
De Kumar, Bony;
Bennett, Brian D;
Wade, Paul A

Publication type:

Article

Differential modulation of the androgen receptor for prostate cancer therapy depends on the DNA response element.

Published in:

Nucleic Acids Research, 2020, v. 48, n. 9, p. 4741, doi. 10.1093/nar/gkaa178

By:

Kregel, Steven;
Bagamasbad, Pia;
He, Shihan;
LaPensee, Elizabeth;
Raji, Yemi;
Brogley, Michele;
Chinnaiyan, Arul;
Cieslik, Marcin;
Robins, Diane M

Publication type:

Article

H2A.Z is dispensable for both basal and activated transcription in post-mitotic mouse muscles.

Published in:

Nucleic Acids Research, 2020, v. 48, n. 9, p. 4601, doi. 10.1093/nar/gkaa157

By:

Belotti, Edwige;
Lacoste, Nicolas;
Simonet, Thomas;
Papin, Christophe;
Padmanabhan, Kiran;
Scionti, Isabella;
Gangloff, Yann-Gaël;
Ramos, Lorrie;
Dalkara, Defne;
Hamiche, Ali;
Dimitrov, Stefan;
Schaeffer, Laurent

Publication type:

Article

TimeMeter assesses temporal gene expression similarity and identifies differentially progressing genes.

Published in:

Nucleic Acids Research, 2020, v. 48, n. 9, p. e51, doi. 10.1093/nar/gkaa142

By:

Jiang, Peng;
Chamberlain, Connie S;
Vanderby, Ray;
Thomson, James A;
Stewart, Ron

Publication type:

Article

Quantitative analysis of transcription factor binding and expression using calling cards reporter arrays.

Published in:

Nucleic Acids Research, 2020, v. 48, n. 9, p. e50, doi. 10.1093/nar/gkaa141

By:

Liu, Jiayue;
Shively, Christian A;
Mitra, Robi D

Publication type:

Article

Cu<sup>2+</sup>-based distance measurements by pulsed EPR provide distance constraints for DNA backbone conformations in solution.

Published in:

Nucleic Acids Research, 2020, v. 48, n. 9, p. e49, doi. 10.1093/nar/gkaa133

By:

Ghosh, Shreya;
Lawless, Matthew J;
Brubaker, Hanna J;
Singewald, Kevin;
Kurpiewski, Michael R;
Jen-Jacobson, Linda;
Saxena, Sunil

Publication type:

Article

Global and local mechanical properties control endonuclease reactivity of a DNA origami nanostructure.

Published in:

Nucleic Acids Research, 2020, v. 48, n. 9, p. 4672, doi. 10.1093/nar/gkaa080

By:

Suma, Antonio;
Stopar, Alex;
Nicholson, Allen W;
Castronovo, Matteo;
Carnevale, Vincenzo

Publication type:

Article