Works matching IS 03051048 AND DT 2020 AND VI 48 AND IP 10

Results: 48

CRISPR–Cas12a system in fission yeast for multiplex genomic editing and CRISPR interference.

Published in:

Nucleic Acids Research, 2020, v. 48, n. 10, p. 5788, doi. 10.1093/nar/gkaa329

By:

Zhao, Yu;
Boeke, Jef D

Publication type:

Article

Emergence of a novel immune-evasion strategy from an ancestral protein fold in bacteriophage Mu.

Published in:

Nucleic Acids Research, 2020, v. 48, n. 10, p. 5294, doi. 10.1093/nar/gkaa319

By:

Karambelkar, Shweta;
Udupa, Shubha;
Gowthami, Vykuntham Naga;
Ramachandra, Sharmila Giliyaru;
Swapna, Ganduri;
Nagaraja, Valakunja

Publication type:

Article

H2B ubiquitylation enhances H3K4 methylation activities of human KMT2 family complexes.

Published in:

Nucleic Acids Research, 2020, v. 48, n. 10, p. 5442, doi. 10.1093/nar/gkaa317

By:

Kwon, Minjung;
Park, Kihyun;
Hyun, Kwangbeom;
Lee, Jeong-Heon;
Zhou, Linjiao;
Cho, Young-Wook;
Ge, Kai;
Skalnik, David G;
Muir, Tom W;
Kim, Jaehoon

Publication type:

Article

The ancillary N-terminal region of the yeast AP-1 transcription factor Yap8 contributes to its DNA binding specificity.

Published in:

Nucleic Acids Research, 2020, v. 48, n. 10, p. 5426, doi. 10.1093/nar/gkaa316

By:

Maciaszczyk-Dziubinska, Ewa;
Reymer, Anna;
Kumar, Nallani Vijay;
Białek, Wojciech;
Mizio, Katarzyna;
Tamás, Markus J;
Wysocki, Robert

Publication type:

Article

Polymorphisms in human immunoglobulin heavy chain variable genes and their upstream regions.

Published in:

Nucleic Acids Research, 2020, v. 48, n. 10, p. 5499, doi. 10.1093/nar/gkaa310

By:

Mikocziova, Ivana;
Gidoni, Moriah;
Lindeman, Ida;
Peres, Ayelet;
Snir, Omri;
Yaari, Gur;
Sollid, Ludvig M

Publication type:

Article

Ribosome profiling in archaea reveals leaderless translation, novel translational initiation sites, and ribosome pausing at single codon resolution.

Published in:

Nucleic Acids Research, 2020, v. 48, n. 10, p. 5201, doi. 10.1093/nar/gkaa304

By:

Gelsinger, Diego Rivera;
Dallon, Emma;
Reddy, Rahul;
Mohammad, Fuad;
Buskirk, Allen R;
DiRuggiero, Jocelyne

Publication type:

Article

Human REXO2 controls short mitochondrial RNAs generated by mtRNA processing and decay machinery to prevent accumulation of double-stranded RNA.

Published in:

Nucleic Acids Research, 2020, v. 48, n. 10, p. 5572, doi. 10.1093/nar/gkaa302

By:

Szewczyk, Maciej;
Malik, Deepshikha;
Borowski, Lukasz S;
Czarnomska, Sylwia D;
Kotrys, Anna V;
Klosowska-Kosicka, Kamila;
Nowotny, Marcin;
Szczesny, Roman J

Publication type:

Article

Evolutionary selection of pestivirus variants with altered or no microRNA dependency.

Published in:

Nucleic Acids Research, 2020, v. 48, n. 10, p. 5555, doi. 10.1093/nar/gkaa300

By:

Kokkonos, Konstantinos G;
Fossat, Nicolas;
Nielsen, Louise;
Holm, Christina;
Hepkema, Wytske M;
Bukh, Jens;
Scheel, Troels K H

Publication type:

Article

Phosphorothioate modified oligonucleotide–protein interactions.

Published in:

Nucleic Acids Research, 2020, v. 48, n. 10, p. 5235, doi. 10.1093/nar/gkaa299

By:

Crooke, Stanley T;
Vickers, Timothy A;
Liang, Xue-hai

Publication type:

Article

Reciprocal regulation of hnRNP C and CELF2 through translation and transcription tunes splicing activity in T cells.

Published in:

Nucleic Acids Research, 2020, v. 48, n. 10, p. 5710, doi. 10.1093/nar/gkaa295

By:

Mallory, Michael J;
McClory, Sean P;
Chatrikhi, Rakesh;
Gazzara, Matthew R;
Ontiveros, Robert J;
Lynch, Kristen W

Publication type:

Article

A splice site-sensing conformational switch in U2AF2 is modulated by U2AF1 and its recurrent myelodysplasia-associated mutation.

Published in:

Nucleic Acids Research, 2020, v. 48, n. 10, p. 5695, doi. 10.1093/nar/gkaa293

By:

Warnasooriya, Chandani;
Feeney, Callen F;
Laird, Kholiswa M;
Ermolenko, Dmitri N;
Kielkopf, Clara L

Publication type:

Article

Regulation of alternative polyadenylation in the yeast Saccharomyces cerevisiae by histone H3K4 and H3K36 methyltransferases.

Published in:

Nucleic Acids Research, 2020, v. 48, n. 10, p. 5407, doi. 10.1093/nar/gkaa292

By:

Kaczmarek Michaels, Katarzyna;
Mohd Mostafa, Salwa;
Ruiz Capella, Julia;
Moore, Claire L

Publication type:

Article

Phage T7 DNA mimic protein Ocr is a potent inhibitor of BREX defence.

Published in:

Nucleic Acids Research, 2020, v. 48, n. 10, p. 5397, doi. 10.1093/nar/gkaa290

By:

Isaev, Artem;
Drobiazko, Alena;
Sierro, Nicolas;
Gordeeva, Julia;
Yosef, Ido;
Qimron, Udi;
Ivanov, Nikolai V;
Severinov, Konstantin

Publication type:

Article

The human telomeric nucleosome displays distinct structural and dynamic properties.

Published in:

Nucleic Acids Research, 2020, v. 48, n. 10, p. 5383, doi. 10.1093/nar/gkaa289

By:

Soman, Aghil;
Liew, Chong Wai;
Teo, Hsiang Ling;
Berezhnoy, Nikolay V;
Olieric, Vincent;
Korolev, Nikolay;
Rhodes, Daniela;
Nordenskiöld, Lars

Publication type:

Article

Generation and validation of structurally defined antibody–siRNA conjugates.

Published in:

Nucleic Acids Research, 2020, v. 48, n. 10, p. 5281, doi. 10.1093/nar/gkaa286

By:

Nanna, Alex R;
Kel'in, Alexander V;
Theile, Christopher;
Pierson, Justin M;
Voo, Zhi Xiang;
Garg, Ashish;
Nair, Jayaprakash K;
Maier, Martin A;
Fitzgerald, Kevin;
Rader, Christoph

Publication type:

Article

Protein disorder-to-order transition enhances the nucleosome-binding affinity of H1.

Published in:

Nucleic Acids Research, 2020, v. 48, n. 10, p. 5318, doi. 10.1093/nar/gkaa285

By:

Sridhar, Akshay;
Orozco, Modesto;
Collepardo-Guevara, Rosana

Publication type:

Article

Cohesin SA1 and SA2 are RNA binding proteins that localize to RNA containing regions on DNA.

Published in:

Nucleic Acids Research, 2020, v. 48, n. 10, p. 5639, doi. 10.1093/nar/gkaa284

By:

Pan, Hai;
Jin, Miao;
Ghadiyaram, Ashwin;
Kaur, Parminder;
Miller, Henry E;
Ta, Hai Minh;
Liu, Ming;
Fan, Yanlin;
Mahn, Chelsea;
Gorthi, Aparna;
You, Changjiang;
Piehler, Jacob;
Riehn, Robert;
Bishop, Alexander J R;
Tao, Yizhi Jane;
Wang, Hong

Publication type:

Article

Revealing thermodynamics of DNA origami folding via affine transformations.

Published in:

Nucleic Acids Research, 2020, v. 48, n. 10, p. 5268, doi. 10.1093/nar/gkaa283

By:

Majikes, Jacob M;
Patrone, Paul N;
Schiffels, Daniel;
Zwolak, Michael;
Kearsley, Anthony J;
Forry, Samuel P;
Liddle, J Alexander

Publication type:

Article

High specificity and tight spatial restriction of self-biotinylation by DNA and RNA G-Quadruplexes complexed in vitro and in vivo with Heme.

Published in:

Nucleic Acids Research, 2020, v. 48, n. 10, p. 5254, doi. 10.1093/nar/gkaa281

By:

Lat, Prince Kumar;
Liu, Kun;
Kumar, Dev N;
Wong, Kenneth K L;
Verheyen, Esther M;
Sen, Dipankar

Publication type:

Article

Peptides containing the PCNA interacting motif APIM bind to the β-clamp and inhibit bacterial growth and mutagenesis.

Published in:

Nucleic Acids Research, 2020, v. 48, n. 10, p. 5540, doi. 10.1093/nar/gkaa278

By:

Nedal, Aina;
Ræder, Synnøve B;
Dalhus, Bjørn;
Helgesen, Emily;
Forstrøm, Rune J;
Lindland, Kim;
Sumabe, Balagra K;
Martinsen, Jacob H;
Kragelund, Birthe B;
Skarstad, Kirsten;
Bjørås, Magnar;
Otterlei, Marit

Publication type:

Article

Spatial organization-dependent EphA2 transcriptional responses revealed by ligand nanocalipers.

Published in:

Nucleic Acids Research, 2020, v. 48, n. 10, p. 5777, doi. 10.1093/nar/gkaa274

By:

Verheyen, Toon;
Fang, Trixy;
Lindenhofer, Dominik;
Wang, Yang;
Akopyan, Karen;
Lindqvist, Arne;
Högberg, Björn;
Teixeira, Ana I

Publication type:

Article

The internal region of CtIP negatively regulates DNA end resection.

Published in:

Nucleic Acids Research, 2020, v. 48, n. 10, p. 5485, doi. 10.1093/nar/gkaa273

By:

Howard, Sean Michael;
Ceppi, Ilaria;
Anand, Roopesh;
Geiger, Roger;
Cejka, Petr

Publication type:

Article

Characterization of Cas12a nucleases reveals diverse PAM profiles between closely-related orthologs.

Published in:

Nucleic Acids Research, 2020, v. 48, n. 10, p. 5624, doi. 10.1093/nar/gkaa272

By:

Jacobsen, Thomas;
Ttofali, Fani;
Liao, Chunyu;
Manchalu, Srinivas;
Gray, Benjamin N;
Beisel, Chase L

Publication type:

Article

IKBKE activity enhances AR levels in advanced prostate cancer via modulation of the Hippo pathway.

Published in:

Nucleic Acids Research, 2020, v. 48, n. 10, p. 5366, doi. 10.1093/nar/gkaa271

By:

Bainbridge, Alex;
Walker, Scott;
Smith, Joseph;
Patterson, Kathryn;
Dutt, Aparna;
Ng, Yi Min;
Thomas, Huw D;
Wilson, Laura;
McCullough, Benjamin;
Jones, Dominic;
Maan, Arussa;
Banks, Peter;
McCracken, Stuart R;
Gaughan, Luke;
Robson, Craig N;
Coffey, Kelly

Publication type:

Article

Targeted mRNA demethylation using an engineered dCas13b-ALKBH5 fusion protein.

Published in:

Nucleic Acids Research, 2020, v. 48, n. 10, p. 5684, doi. 10.1093/nar/gkaa269

By:

Li, Jiexin;
Chen, Zhuojia;
Chen, Feng;
Xie, Guoyou;
Ling, Yuyi;
Peng, Yanxi;
Lin, Yu;
Luo, Nan;
Chiang, Cheng-Ming;
Wang, Hongsheng

Publication type:

Article

A distinct role for recombination repair factors in an early cellular response to transcription–replication conflicts.

Published in:

Nucleic Acids Research, 2020, v. 48, n. 10, p. 5467, doi. 10.1093/nar/gkaa268

By:

Shao, Xin;
Joergensen, Amalie M;
Howlett, Niall G;
Lisby, Michael;
Oestergaard, Vibe H

Publication type:

Article

Structural and functional insights into CWC27/CWC22 heterodimer linking the exon junction complex to spliceosomes.

Published in:

Nucleic Acids Research, 2020, v. 48, n. 10, p. 5670, doi. 10.1093/nar/gkaa267

By:

Busetto, Virginia;
Barbosa, Isabelle;
Basquin, Jérôme;
Marquenet, Émelie;
Hocq, Rémi;
Hennion, Magali;
Paternina, Janio Antonio;
Namane, Abdelkader;
Conti, Elena;
Bensaude, Olivier;
Le Hir, Hervé

Publication type:

Article

Methyltransferase DnmA is responsible for genome-wide N6-methyladenosine modifications at non-palindromic recognition sites in Bacillus subtilis.

Published in:

Nucleic Acids Research, 2020, v. 48, n. 10, p. 5332, doi. 10.1093/nar/gkaa266

By:

Nye, Taylor M;
van Gijtenbeek, Lieke A;
Stevens, Amanda G;
Schroeder, Jeremy W;
Randall, Justin R;
Matthews, Lindsay A;
Simmons, Lyle A

Publication type:

Article

To Petabytes and beyond: recent advances in probabilistic and signal processing algorithms and their application to metagenomics.

Published in:

Nucleic Acids Research, 2020, v. 48, n. 10, p. 5217, doi. 10.1093/nar/gkaa265

By:

Elworth, R A Leo;
Wang, Qi;
Kota, Pavan K;
Barberan, C J;
Coleman, Benjamin;
Balaji, Advait;
Gupta, Gaurav;
Baraniuk, Richard G;
Shrivastava, Anshumali;
Treangen, Todd J

Publication type:

Article

O-GlcNAc regulates gene expression by controlling detained intron splicing.

Published in:

Nucleic Acids Research, 2020, v. 48, n. 10, p. 5656, doi. 10.1093/nar/gkaa263

By:

Tan, Zhi-Wei;
Fei, George;
Paulo, Joao A;
Bellaousov, Stanislav;
Martin, Sara E S;
Duveau, Damien Y;
Thomas, Craig J;
Gygi, Steven P;
Boutz, Paul L;
Walker, Suzanne

Publication type:

Article

High resolution crystal structure of a KRAS promoter G-quadruplex reveals a dimer with extensive poly-A π-stacking interactions for small-molecule recognition.

Published in:

Nucleic Acids Research, 2020, v. 48, n. 10, p. 5766, doi. 10.1093/nar/gkaa262

By:

Ou, Arnold;
Schmidberger, Jason W;
Wilson, Katie A;
Evans, Cameron W;
Hargreaves, Jessica A;
Grigg, Melanie;
O'Mara, Megan L;
Iyer, K Swaminathan;
Bond, Charles S;
Smith, Nicole M

Publication type:

Article

RNase AM, a 5′ to 3′ exonuclease, matures the 5′ end of all three ribosomal RNAs in E. coli.

Published in:

Nucleic Acids Research, 2020, v. 48, n. 10, p. 5616, doi. 10.1093/nar/gkaa260

By:

Jain, Chaitanya

Publication type:

Article

Structural and functional characterization of the severe fever with thrombocytopenia syndrome virus L protein.

Published in:

Nucleic Acids Research, 2020, v. 48, n. 10, p. 5749, doi. 10.1093/nar/gkaa253

By:

Vogel, Dominik;
Thorkelsson, Sigurdur Rafn;
Quemin, Emmanuelle R J;
Meier, Kristina;
Kouba, Tomas;
Gogrefe, Nadja;
Busch, Carola;
Reindl, Sophia;
Günther, Stephan;
Cusack, Stephen;
Grünewald, Kay;
Rosenthal, Maria

Publication type:

Article

A proteinase-free DNA replication machinery for in vitro and in vivo amplified MicroRNA imaging.

Published in:

Nucleic Acids Research, 2020, v. 48, n. 10, p. e60, doi. 10.1093/nar/gkaa250

By:

Wei, Jie;
Wang, Huimin;
Gong, Xue;
Wang, Qing;
Wang, Hong;
Zhou, Yangjie;
Wang, Fuan

Publication type:

Article

EXOSC10 sculpts the transcriptome during the growth-to-maturation transition in mouse oocytes.

Published in:

Nucleic Acids Research, 2020, v. 48, n. 10, p. 5349, doi. 10.1093/nar/gkaa249

By:

Wu, Di;
Dean, Jurrien

Publication type:

Article

Phase-plate cryo-EM structure of the Widom 601 CENP-A nucleosome core particle reveals differential flexibility of the DNA ends.

Published in:

Nucleic Acids Research, 2020, v. 48, n. 10, p. 5735, doi. 10.1093/nar/gkaa246

By:

Boopathi, Ramachandran;
Danev, Radostin;
Khoshouei, Maryam;
Kale, Seyit;
Nahata, Sunil;
Ramos, Lorrie;
Angelov, Dimitar;
Dimitrov, Stefan;
Hamiche, Ali;
Petosa, Carlo;
Bednar, Jan

Publication type:

Article

Simultaneous measurement of biochemical phenotypes and gene expression in single cells.

Published in:

Nucleic Acids Research, 2020, v. 48, n. 10, p. e59, doi. 10.1093/nar/gkaa240

By:

Richer, Amanda L;
Riemondy, Kent A;
Hardie, Lakotah;
Hesselberth, Jay R

Publication type:

Article

Caveat mutator: alanine substitutions for conserved amino acids in RNA ligase elicit unexpected rearrangements of the active site for lysine adenylylation.

Published in:

Nucleic Acids Research, 2020, v. 48, n. 10, p. 5603, doi. 10.1093/nar/gkaa238

By:

Unciuleac, Mihaela-Carmen;
Goldgur, Yehuda;
Shuman, Stewart

Publication type:

Article

Temperature controlled high-throughput magnetic tweezers show striking difference in activation energies of replicating viral RNA-dependent RNA polymerases.

Published in:

Nucleic Acids Research, 2020, v. 48, n. 10, p. 5591, doi. 10.1093/nar/gkaa233

By:

Seifert, Mona;
van Nies, Pauline;
Papini, Flávia S;
Arnold, Jamie J;
Poranen, Minna M;
Cameron, Craig E;
Depken, Martin;
Dulin, David

Publication type:

Article

Extinction of all infectious HIV in cell culture by the CRISPR-Cas12a system with only a single crRNA.

Published in:

Nucleic Acids Research, 2020, v. 48, n. 10, p. 5527, doi. 10.1093/nar/gkaa226

By:

Gao, Zongliang;
Fan, Minghui;
Das, Atze T;
Herrera-Carrillo, Elena;
Berkhout, Ben

Publication type:

Article

Pervasive and CpG-dependent promoter-like characteristics of transcribed enhancers.

Published in:

Nucleic Acids Research, 2020, v. 48, n. 10, p. 5306, doi. 10.1093/nar/gkaa223

By:

Steinhaus, Robin;
Gonzalez, Tonatiuh;
Seelow, Dominik;
Robinson, Peter N

Publication type:

Article

Polyphosphate induces the proteolysis of ADP-bound fraction of initiator to inhibit DNA replication initiation upon stress in Escherichia coli.

Published in:

Nucleic Acids Research, 2020, v. 48, n. 10, p. 5457, doi. 10.1093/nar/gkaa217

By:

Gross, Marta H;
Konieczny, Igor

Publication type:

Article

PRMT7 regulates RNA-binding capacity and protein stability in Leishmania parasites.

Published in:

Nucleic Acids Research, 2020, v. 48, n. 10, p. 5511, doi. 10.1093/nar/gkaa211

By:

Ferreira, Tiago R;
Dowle, Adam A;
Parry, Ewan;
Alves-Ferreira, Eliza V C;
Hogg, Karen;
Kolokousi, Foteini;
Larson, Tony R;
Plevin, Michael J;
Cruz, Angela K;
Walrad, Pegine B

Publication type:

Article

Isolation and analysis of rereplicated DNA by Rerep-Seq.

Published in:

Nucleic Acids Research, 2020, v. 48, n. 10, p. e58, doi. 10.1093/nar/gkaa197

By:

Menzel, Johannes;
Tatman, Philip;
Black, Joshua C

Publication type:

Article

Efficient and risk-reduced genome editing using double nicks enhanced by bacterial recombination factors in multiple species.

Published in:

Nucleic Acids Research, 2020, v. 48, n. 10, p. e57, doi. 10.1093/nar/gkaa195

By:

He, Xiaozhen;
Chen, Wenfeng;
Liu, Zhen;
Yu, Guirong;
Chen, Youbang;
Cai, Yi-Jun;
Sun, Ling;
Xu, Wanli;
Zhong, Lili;
Gao, Caixi;
Chen, Jishen;
Zhang, Minjie;
Yang, Shengxi;
Yao, Yizhou;
Zhang, Zhiping;
Ma, Fujun;
Zhang, Chen-Chen;
Lu, Hui-Ping;
Yu, Bin;
Cheng, Tian-Lin

Publication type:

Article

Uncovering the key dimensions of high-throughput biomolecular data using deep learning.

Published in:

Nucleic Acids Research, 2020, v. 48, n. 10, p. e56, doi. 10.1093/nar/gkaa191

By:

Zhang, Shixiong;
Li, Xiangtao;
Lin, Qiuzhen;
Lin, Jiecong;
Wong, Ka-Chun

Publication type:

Article

SingleCellSignalR: inference of intercellular networks from single-cell transcriptomics.

Published in:

Nucleic Acids Research, 2020, v. 48, n. 10, p. e55, doi. 10.1093/nar/gkaa183

By:

Cabello-Aguilar, Simon;
Alame, Mélissa;
Kon-Sun-Tack, Fabien;
Fau, Caroline;
Lacroix, Matthieu;
Colinge, Jacques

Publication type:

Article

The hTERT core promoter forms three parallel G-quadruplexes.

Published in:

Nucleic Acids Research, 2020, v. 48, n. 10, p. 5720, doi. 10.1093/nar/gkaa107

By:

Monsen, Robert C;
DeLeeuw, Lynn;
Dean, William L;
Gray, Robert D;
Sabo, T Michael;
Chakravarthy, Srinivas;
Chaires, Jonathan B;
Trent, John O

Publication type:

Article