Works matching IS 03051048 AND DT 2018 AND VI 46 AND IP 16

Results: 53

A novel λ integrase-mediated seamless vector transgenesis platform for therapeutic protein expression.

Published in:

Nucleic Acids Research, 2018, v. 46, n. 16, p. 1, doi. 10.1093/nar/gky500

By:

Makhija, Harshyaa;
Roy, Suki;
Hoon, Shawn;
Ghadessy, Farid John;
Wong, Desmond;
Jaiswal, Rahul;
Campana, Dario;
Dröge, Peter

Publication type:

Article

Triazole linking for preparation of a next-generation sequencing library from single-stranded DNA.

Published in:

Nucleic Acids Research, 2018, v. 46, n. 16, p. e95, doi. 10.1093/nar/gky452

By:

Miura, Fumihito;
Fujino, Tomoko;
Kogashi, Kanako;
Shibata, Yukiko;
Miura, Miki;
Isobe, Hiroyuki;
Ito, Takashi

Publication type:

Article

SWI/SNF interacts with cleavage and polyadenylation factors and facilitates pre-mRNA 3′ end processing.

Published in:

Nucleic Acids Research, 2018, v. 46, n. 16, p. 8557, doi. 10.1093/nar/gky438

By:

Yu, Simei;
Jordán-Pla, Antonio;
Gañez-Zapater, Antoni;
Jain, Shruti;
Rolicka, Anna;
Östlund Farrants, Ann-Kristin;
Visa, Neus

Publication type:

Article

Structural insights into Drosophila-C3PO complex assembly and 'Dynamic Side Port' model in substrate entry and release.

Published in:

Nucleic Acids Research, 2018, v. 46, n. 16, p. 8590, doi. 10.1093/nar/gky465

By:

Mo, Xiaobing;
Yang, Xia;
Yuan, Yuren Adam

Publication type:

Article

Structural dynamics of translation elongation factor Tu during aa-tRNA delivery to the ribosome.

Published in:

Nucleic Acids Research, 2018, v. 46, n. 16, p. 8651, doi. 10.1093/nar/gky651

By:

Kavaliauskas, Darius;
Chen, Chunlai;
Liu, Wei;
Cooperman, Barry S;
Goldman, Yale E;
Knudsen, Charlotte R

Publication type:

Article

Structural basis for the synergy of 4′- and 2′-modifications on siRNA nuclease resistance, thermal stability and RNAi activity.

Published in:

Nucleic Acids Research, 2018, v. 46, n. 16, p. 8090, doi. 10.1093/nar/gky703

By:

Harp, Joel M;
Guenther, Dale C;
Bisbe, Anna;
Perkins, Lydia;
Matsuda, Shigeo;
Bommineni, Gopal R;
Zlatev, Ivan;
Foster, Donald J;
Taneja, Nate;
Charisse, Klaus

Publication type:

Article

Structural accommodations accompanying splicing of a group II intron RNP.

Published in:

Nucleic Acids Research, 2018, v. 46, n. 16, p. 8542, doi. 10.1093/nar/gky416

By:

Dong, Xiaolong;
Ranganathan, Srivathsan;
Qu, Guosheng;
Piazza, Carol Lyn;
Belfort, Marlene

Publication type:

Article

A strongly pairing fifth base: oligonucleotides with a C-nucleoside replacing thymidine.

Published in:

Nucleic Acids Research, 2018, v. 46, n. 16, p. 8069, doi. 10.1093/nar/gky669

By:

Walter, Tanja J;
Richert, Clemens

Publication type:

Article

Small synthetic molecule-stabilized RNA pseudoknot as an activator for –1 ribosomal frameshifting.

Published in:

Nucleic Acids Research, 2018, v. 46, n. 16, p. 8079, doi. 10.1093/nar/gky689

By:

Matsumoto, Saki;
Caliskan, Neva;
Rodnina, Marina V;
Murata, Asako;
Nakatani, Kazuhiko

Publication type:

Article

Single molecule kinetics uncover roles for E. coli RecQ DNA helicase domains and interaction with SSB.

Published in:

Nucleic Acids Research, 2018, v. 46, n. 16, p. 8500, doi. 10.1093/nar/gky647

By:

Bagchi, Debjani;
Manosas, Maria;
Zhang, Weiting;
Manthei, Kelly A;
Hodeib, Samar;
Ducos, Bertrand;
Keck, James L;
Croquette, Vincent

Publication type:

Article

The signature motif of the Saccharomyces cerevisiae Pif1 DNA helicase is essential in vivo for mitochondrial and nuclear functions and in vitro for ATPase activity.

Published in:

Nucleic Acids Research, 2018, v. 46, n. 16, p. 8357, doi. 10.1093/nar/gky655

By:

Geronimo, Carly L;
Singh, Saurabh P;
Galletto, Roberto;
Zakian, Virginia A

Publication type:

Article

Shared nucleotide flanks confer transcriptional competency to bZip core motifs.

Published in:

Nucleic Acids Research, 2018, v. 46, n. 16, p. 8371, doi. 10.1093/nar/gky681

By:

Cohen, Daniel M;
Lim, Hee-Woong;
Won, Kyoung-Jae;
Steger, David J

Publication type:

Article

The sequence features that define efficient and specific hAGO2-dependent miRNA silencing guides.

Published in:

Nucleic Acids Research, 2018, v. 46, n. 16, p. 8181, doi. 10.1093/nar/gky546

By:

Yan, Yifei;
Acevedo, Mariana;
Mignacca, Lian;
Desjardins, Philippe;
Scott, Nicolas;
Imane, Roqaya;
Quenneville, Jordan;
Robitaille, Julie;
Feghaly, Albert;
Gagnon, Etienne

Publication type:

Article

SB Driver Analysis: a Sleeping Beauty cancer driver analysis framework for identifying and prioritizing experimentally actionable oncogenes and tumor suppressors.

Published in:

Nucleic Acids Research, 2018, v. 46, n. 16, p. e94, doi. 10.1093/nar/gky450

By:

Newberg, Justin Y;
Black, Michael A;
Jenkins, Nancy A;
Copeland, Neal G;
Mann, Karen M;
Mann, Michael B

Publication type:

Article

Rpd3L HDAC links H3K4me3 to transcriptional repression memory.

Published in:

Nucleic Acids Research, 2018, v. 46, n. 16, p. 8261, doi. 10.1093/nar/gky573

By:

Lee, Bo Bae;
Choi, Ahyoung;
Kim, Ji Hyun;
Jun, Yukyung;
Woo, Hyeonju;
Ha, So Dam;
Yoon, Chae Young;
Hwang, Jin-Taek;
Steinmetz, Lars;
Buratowski, Stephen

Publication type:

Article

RNA Framework: an all-in-one toolkit for the analysis of RNA structures and post-transcriptional modifications.

Published in:

Nucleic Acids Research, 2018, v. 46, n. 16, p. e97, doi. 10.1093/nar/gky486

By:

Incarnato, Danny;
Morandi, Edoardo;
Simon, Lisa Marie;
Oliviero, Salvatore

Publication type:

Article

Revealing a human p53 universe.

Published in:

Nucleic Acids Research, 2018, v. 46, n. 16, p. 8153, doi. 10.1093/nar/gky720

By:

Nguyen, Thuy-Ai T;
Grimm, Sara A;
Bushel, Pierre R;
Li, Jianying;
Li, Yuanyuan;
Bennett, Brian D;
Lavender, Christopher A;
Ward, James M;
Fargo, David C;
Anderson, Carl W

Publication type:

Article

RBPJ binds to consensus and methylated cis elements within phased nucleosomes and controls gene expression in human aortic smooth muscle cells in cooperation with SRF.

Published in:

Nucleic Acids Research, 2018, v. 46, n. 16, p. 8232, doi. 10.1093/nar/gky562

By:

Rozenberg, Julian M;
Taylor, Joan M;
Mack, Christopher P

Publication type:

Article

RBPJ binds to consensus and methylated cis elements within phased nucleosomes and controls gene expression in human aortic smooth muscle cells in cooperation with SRF.

Published in:

Nucleic Acids Research, 2018, v. 46, n. 16, p. 8662, doi. 10.1093/nar/gky617

By:

Rozenberg, Julian M;
Taylor, Joan M;
Mack, Christopher P

Publication type:

Article

The Pif1 signature motif of Pfh1 is necessary for both protein displacement and helicase unwinding activities, but is dispensable for strand-annealing activity.

Published in:

Nucleic Acids Research, 2018, v. 46, n. 16, p. 8516, doi. 10.1093/nar/gky654

By:

Mohammad, Jani B;
Wallgren, Marcus;
Sabouri, Nasim

Publication type:

Article

A multivariate prediction model for Rho-dependent termination of transcription.

Published in:

Nucleic Acids Research, 2018, v. 46, n. 16, p. 8245, doi. 10.1093/nar/gky563

By:

Nadiras, Cédric;
Eveno, Eric;
Schwartz, Annie;
Figueroa-Bossi, Nara;
Boudvillain, Marc

Publication type:

Article

MTG1 couples mitoribosome large subunit assembly with intersubunit bridge formation.

Published in:

Nucleic Acids Research, 2018, v. 46, n. 16, p. 8435, doi. 10.1093/nar/gky672

By:

Kim, Hyun-Jung;
Barrientos, Antoni

Publication type:

Article

mRNAs are sorted for export or degradation before passing through nuclear speckles.

Published in:

Nucleic Acids Research, 2018, v. 46, n. 16, p. 8404, doi. 10.1093/nar/gky650

By:

Fan, Jing;
Kuai, Bin;
Wang, Ke;
Wang, Lantian;
Wang, Yimin;
Wu, Xudong;
Chi, Binkai;
Li, Guohui;
Cheng, Hong

Publication type:

Article

Insights into the development of chemical probes for RNA.

Published in:

Nucleic Acids Research, 2018, v. 46, n. 16, p. 8025, doi. 10.1093/nar/gky718

By:

Morgan, Brittany S;
Forte, Jordan E;
Hargrove, Amanda E

Publication type:

Article

In vivo genome-wide binding interactions of mouse and human constitutive androstane receptors reveal novel gene targets.

Published in:

Nucleic Acids Research, 2018, v. 46, n. 16, p. 8385, doi. 10.1093/nar/gky692

By:

Niu, Ben;
Coslo, Denise M;
Bataille, Alain R;
Albert, Istvan;
Pugh, B Franklin;
Omiecinski, Curtis J

Publication type:

Article

In vitro selection of an XNA aptamer capable of small-molecule recognition.

Published in:

Nucleic Acids Research, 2018, v. 46, n. 16, p. 8057, doi. 10.1093/nar/gky667

By:

Rangel, Alexandra E;
Chen, Zhe;
Ayele, Tewoderos M;
Heemstra, Jennifer M

Publication type:

Article

i-Motif DNA: structural features and significance to cell biology.

Published in:

Nucleic Acids Research, 2018, v. 46, n. 16, p. 8038, doi. 10.1093/nar/gky735

By:

Abou Assi, Hala;
Garavís, Miguel;
González, Carlos;
Damha, Masad J

Publication type:

Article

The human Obg protein GTPBP10 is involved in mitoribosomal biogenesis.

Published in:

Nucleic Acids Research, 2018, v. 46, n. 16, p. 8471, doi. 10.1093/nar/gky701

By:

Lavdovskaia, Elena;
Kolander, Elisa;
Steube, Emely;
Mai, Mandy Mong-Quyen;
Urlaub, Henning;
Richter-Dennerlein, Ricarda

Publication type:

Article

HIV-1 Vpr and p21 restrict LINE-1 mobility.

Published in:

Nucleic Acids Research, 2018, v. 46, n. 16, p. 8454, doi. 10.1093/nar/gky688

By:

Kawano, Koudai;
Doucet, Aurélien J;
Ueno, Mikinori;
Kariya, Ryusho;
An, Wenfeng;
Marzetta, Flavia;
Kuroki, Misao;
Turelli, Priscilla;
Sukegawa, Sayaka;
Okada, Seiji

Publication type:

Article

Histone variant H2A.Z deposition and acetylation directs the canonical Notch signaling response.

Published in:

Nucleic Acids Research, 2018, v. 46, n. 16, p. 8197, doi. 10.1093/nar/gky551

By:

Giaimo, Benedetto Daniele;
Ferrante, Francesca;
Vallejo, Diana M;
Hein, Kerstin;
Gutierrez-Perez, Irene;
Nist, Andrea;
Stiewe, Thorsten;
Mittler, Gerhard;
Herold, Susanne;
Zimmermann, Tobias

Publication type:

Article

The helicase Pif1 functions in the template switching pathway of DNA damage bypass.

Published in:

Nucleic Acids Research, 2018, v. 46, n. 16, p. 8347, doi. 10.1093/nar/gky648

By:

García-Rodríguez, Néstor;
Wong, Ronald P;
Ulrich, Helle D

Publication type:

Article

Germline DNA replication timing shapes mammalian genome composition.

Published in:

Nucleic Acids Research, 2018, v. 46, n. 16, p. 8299, doi. 10.1093/nar/gky610

By:

Yehuda, Yishai;
Blumenfeld, Britny;
Mayorek, Nina;
Makedonski, Kirill;
Vardi, Oriya;
Cohen-Daniel, Leonor;
Mansour, Yousef;
Baror-Sebban, Shulamit;
Masika, Hagit;
Farago, Marganit

Publication type:

Article

A genome-wide scan for correlated mutations detects macromolecular and chromatin interactions in Arabidopsis thaliana.

Published in:

Nucleic Acids Research, 2018, v. 46, n. 16, p. 8114, doi. 10.1093/nar/gky576

By:

Perlaza-Jiménez, Laura;
Walther, Dirk

Publication type:

Article

Generating genomic platforms to study Candida albicans pathogenesis.

Published in:

Nucleic Acids Research, 2018, v. 46, n. 16, p. 8664, doi. 10.1093/nar/gky747

By:

Legrand, Mélanie;
Bachellier-Bassi, Sophie;
Lee, Keunsook K;
Chaudhari, Yogesh;
Tournu, Hélène;
Arbogast, Laurence;
Boyer, Hélène;
Chauvel, Murielle;
Cabral, Vitor;
Maufrais, Corinne

Publication type:

Article

Faithful chromosome segregation in Trypanosoma brucei requires a cohort of divergent spindle-associated proteins with distinct functions.

Published in:

Nucleic Acids Research, 2018, v. 46, n. 16, p. 8216, doi. 10.1093/nar/gky557

By:

Zhou, Qing;
Lee, Kyu Joon;
Kurasawa, Yasuhiro;
Hu, Huiqing;
An, Tai;
Li, Ziyin

Publication type:

Article

Evolutionary insights into Trm112-methyltransferase holoenzymes involved in translation between archaea and eukaryotes.

Published in:

Nucleic Acids Research, 2018, v. 46, n. 16, p. 8483, doi. 10.1093/nar/gky638

By:

van Tran, Nhan;
Muller, Leslie;
Ross, Robert L;
Lestini, Roxane;
Létoquart, Juliette;
Ulryck, Nathalie;
Limbach, Patrick A;
de Crécy-Lagard, Valérie;
Cianférani, Sarah;
Graille, Marc

Publication type:

Article

EVI1 carboxy-terminal phosphorylation is ATM-mediated and sustains transcriptional modulation and self-renewal via enhanced CtBP1 association.

Published in:

Nucleic Acids Research, 2018, v. 46, n. 16, p. 8663, doi. 10.1093/nar/gky711

By:

Paredes, Roberto;
Schneider, Marion;
Stevens, Adam;
White, Daniel J;
K. Williamson, Andrew J;
Muter, Joanne;
Pearson, Stella;
Kelly, James R;
Connors, Kathleen;
Wiseman, Daniel H

Publication type:

Article

The essential nature of YqfG, a YbeY homologue required for 3′ maturation of Bacillus subtilis 16S ribosomal RNA is suppressed by deletion of RNase R.

Published in:

Nucleic Acids Research, 2018, v. 46, n. 16, p. 8605, doi. 10.1093/nar/gky488

By:

Baumgardt, Kathrin;
Gilet, Laetitia;
Figaro, Sabine;
Condon, Ciarán

Publication type:

Article

Entropy-driven DNA logic circuits regulated by DNAzyme.

Published in:

Nucleic Acids Research, 2018, v. 46, n. 16, p. 8532, doi. 10.1093/nar/gky663

By:

Yang, Jing;
Wu, Ranfeng;
Li, Yifan;
Wang, Zhiyu;
Pan, Linqiang;
Zhang, Qiang;
Lu, Zuhong;
Zhang, Cheng

Publication type:

Article

Efficient CRISPR/Cas9-mediated editing of trinucleotide repeat expansion in myotonic dystrophy patient-derived iPS and myogenic cells.

Published in:

Nucleic Acids Research, 2018, v. 46, n. 16, p. 8275, doi. 10.1093/nar/gky548

By:

Dastidar, Sumitava;
Ardui, Simon;
Singh, Kshitiz;
Majumdar, Debanjana;
Nair, Nisha;
Fu, Yanfang;
Reyon, Deepak;
Samara, Ermira;
Gerli, Mattia F M;
Klein, Arnaud F

Publication type:

Article

E. coli elongation factor Tu bound to a GTP analogue displays an open conformation equivalent to the GDP-bound form.

Published in:

Nucleic Acids Research, 2018, v. 46, n. 16, p. 8641, doi. 10.1093/nar/gky697

By:

Johansen, Jesper S;
Kavaliauskas, Darius;
Pfeil, Shawn H;
Blaise, Mickaël;
Cooperman, Barry S;
Goldman, Yale E;
Thirup, Søren S;
Knudsen, Charlotte R

Publication type:

Article

DNA binding with a minimal scaffold: structure–function analysis of Lig E DNA ligases.

Published in:

Nucleic Acids Research, 2018, v. 46, n. 16, p. 8616, doi. 10.1093/nar/gky622

By:

Williamson, Adele;
Grgic, Miriam;
Leiros, Hanna-Kirsti S

Publication type:

Article

A deep recurrent neural network discovers complex biological rules to decipher RNA protein-coding potential.

Published in:

Nucleic Acids Research, 2018, v. 46, n. 16, p. 8105, doi. 10.1093/nar/gky567

By:

Hill, Steven T;
Kuintzle, Rachael;
Teegarden, Amy;
Merrill, Erich;
Danaee, Padideh;
Hendrix, David A

Publication type:

Article

Decoding non-random mutational signatures at Cas9 targeted sites.

Published in:

Nucleic Acids Research, 2018, v. 46, n. 16, p. 8417, doi. 10.1093/nar/gky653

By:

Taheri-Ghahfarokhi, Amir;
Taylor, Benjamin J M;
Nitsch, Roberto;
Lundin, Anders;
Cavallo, Anna-Lina;
Madeyski-Bengtson, Katja;
Karlsson, Fredrik;
Clausen, Maryam;
Hicks, Ryan;
Mayr, Lorenz M

Publication type:

Article

Crystal structure of dimeric human PNPase reveals why disease-linked mutants suffer from low RNA import and degradation activities.

Published in:

Nucleic Acids Research, 2018, v. 46, n. 16, p. 8630, doi. 10.1093/nar/gky642

By:

Golzarroshan, Bagher;
Lin, Chia-Liang;
Li, Chia-Lung;
Yang, Wei-Zen;
Chu, Lee-Ya;
Agrawal, Sashank;
Yuan, Hanna S

Publication type:

Article

Computational analysis of ribonomics datasets identifies long non-coding RNA targets of γ-herpesviral miRNAs.

Published in:

Nucleic Acids Research, 2018, v. 46, n. 16, p. 8574, doi. 10.1093/nar/gky459

By:

Sethuraman, Sunantha;
Thomas, Merin;
Gay, Lauren A;
Renne, Rolf

Publication type:

Article

Combined deficiency of Senataxin and DNA-PKcs causes DNA damage accumulation and neurodegeneration in spinal muscular atrophy.

Published in:

Nucleic Acids Research, 2018, v. 46, n. 16, p. 8326, doi. 10.1093/nar/gky641

By:

Kannan, Annapoorna;
Bhatia, Kanchan;
Branzei, Dana;
Gangwani, Laxman

Publication type:

Article

Circular RNA expression in human hematopoietic cells is widespread and cell-type specific.

Published in:

Nucleic Acids Research, 2018, v. 46, n. 16, p. 8168, doi. 10.1093/nar/gky721

By:

Nicolet, Benoit P;
Engels, Sander;
Aglialoro, Francesca;
van den Akker, Emile;
von Lindern, Marieke;
Wolkers, Monika C

Publication type:

Article

Characterizing the 3D structure and dynamics of chromosomes and proteins in a common contact matrix framework.

Published in:

Nucleic Acids Research, 2018, v. 46, n. 16, p. 8143, doi. 10.1093/nar/gky604

By:

Lindsay, Richard J;
Pham, Bill;
Shen, Tongye;
McCord, Rachel Patton

Publication type:

Article

BASiNET—BiologicAl Sequences NETwork: a case study on coding and non-coding RNAs identification.

Published in:

Nucleic Acids Research, 2018, v. 46, n. 16, p. e96, doi. 10.1093/nar/gky462

By:

Ito, Eric Augusto;
Katahira, Isaque;
Vicente, Fábio Fernandes da Rocha;
Pereira, Luiz Filipe Protasio;
Lopes, Fabrício Martins

Publication type:

Article