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Developmental and cancer-associated plasticity of DNA replication preferentially targets GC-poor, lowly expressed and late-replicating regions.
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- Nucleic Acids Research, 2018, v. 46, n. 19, p. 10157, doi. 10.1093/nar/gky797
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Developmental and cancer-associated plasticity of DNA replication preferentially targets GC-poor, lowly expressed and late-replicating regions.
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- Nucleic Acids Research, 2018, v. 46, n. 19, p. 10532, doi. 10.1093/nar/gky849
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Deep genome annotation of the opportunistic human pathogen Streptococcus pneumoniae D39.
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- Nucleic Acids Research, 2018, v. 46, n. 19, p. 9971, doi. 10.1093/nar/gky725
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Crystal structure of the modification-dependent SRA-HNH endonuclease TagI.
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- Nucleic Acids Research, 2018, v. 46, n. 19, p. 10489, doi. 10.1093/nar/gky781
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ZBTB24 is a transcriptional regulator that coordinates with DNMT3B to control DNA methylation.
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- Nucleic Acids Research, 2018, v. 46, n. 19, p. 10034, doi. 10.1093/nar/gky682
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T4 DNA ligase structure reveals a prototypical ATP-dependent ligase with a unique mode of sliding clamp interaction.
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- Nucleic Acids Research, 2018, v. 46, n. 19, p. 10474, doi. 10.1093/nar/gky776
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Unexpected functional versatility of the pentatricopeptide repeat proteins PGR3, PPR5 and PPR10.
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- Nucleic Acids Research, 2018, v. 46, n. 19, p. 10448, doi. 10.1093/nar/gky737
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A Type III-B Cmr effector complex catalyzes the synthesis of cyclic oligoadenylate second messengers by cooperative substrate binding.
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- Nucleic Acids Research, 2018, v. 46, n. 19, p. 10319, doi. 10.1093/nar/gky844
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Transcription-driven genome organization: a model for chromosome structure and the regulation of gene expression tested through simulations.
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- Nucleic Acids Research, 2018, v. 46, n. 19, p. 9895, doi. 10.1093/nar/gky763
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Vibrio cholerae chromosome 2 copy number is controlled by the methylation-independent binding of its monomeric initiator to the chromosome 1 crtS site.
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- Nucleic Acids Research, 2018, v. 46, n. 19, p. 10145, doi. 10.1093/nar/gky790
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CRISPR–Cas adaptation in Escherichia coli requires RecBCD helicase but not nuclease activity, is independent of homologous recombination, and is antagonized by 5′ ssDNA exonucleases.
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- Nucleic Acids Research, 2018, v. 46, n. 19, p. 10173, doi. 10.1093/nar/gky799
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Systematic exploration of cell morphological phenotypes associated with a transcriptomic query.
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- Nucleic Acids Research, 2018, v. 46, n. 19, p. e116, doi. 10.1093/nar/gky626
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Systematic editing of synthetic RIG-I ligands to produce effective antiviral and anti-tumor RNA immunotherapies.
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- Nucleic Acids Research, 2018, v. 46, n. 19, p. 10533, doi. 10.1093/nar/gky819
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Structural insights into the mechanism of double strand break formation by Hermes, a hAT family eukaryotic DNA transposase.
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- Nucleic Acids Research, 2018, v. 46, n. 19, p. 10286, doi. 10.1093/nar/gky838
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Structural characterization of maternally expressed gene 3 RNA reveals conserved motifs and potential sites of interaction with polycomb repressive complex 2.
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- Nucleic Acids Research, 2018, v. 46, n. 19, p. 10432, doi. 10.1093/nar/gky722
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Structural basis of chimpanzee APOBEC3H dimerization stabilized by double-stranded RNA.
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- Nucleic Acids Research, 2018, v. 46, n. 19, p. 10368, doi. 10.1093/nar/gky676
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Structural analysis of the ternary complex between lamin A/C, BAF and emerin identifies an interface disrupted in autosomal recessive progeroid diseases.
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- Nucleic Acids Research, 2018, v. 46, n. 19, p. 10460, doi. 10.1093/nar/gky736
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Site-specific amino acid substitution in dodecameric peptides determines the stability and unfolding of c-MYC quadruplex promoting apoptosis in cancer cells.
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- Nucleic Acids Research, 2018, v. 46, n. 19, p. 9932, doi. 10.1093/nar/gky824
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A single molecule analysis of H-NS uncouples DNA binding affinity from DNA specificity.
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- Nucleic Acids Research, 2018, v. 46, n. 19, p. 10216, doi. 10.1093/nar/gky826
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Sequence preference and structural heterogeneity of BZ junctions.
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- Nucleic Acids Research, 2018, v. 46, n. 19, p. 10504, doi. 10.1093/nar/gky784
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Schizosaccharomyces pombe Pol II transcription elongation factor ELL functions as part of a rudimentary super elongation complex.
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- Nucleic Acids Research, 2018, v. 46, n. 19, p. 10095, doi. 10.1093/nar/gky713
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COPII vesicles can affect the activity of antisense oligonucleotides by facilitating the release of oligonucleotides from endocytic pathways.
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- Nucleic Acids Research, 2018, v. 46, n. 19, p. 10225, doi. 10.1093/nar/gky841
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Role of nucleotide identity in effective CRISPR target escape mutations.
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- Nucleic Acids Research, 2018, v. 46, n. 19, p. 10395, doi. 10.1093/nar/gky687
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Robustness by intrinsically disordered C-termini and translational readthrough.
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- Nucleic Acids Research, 2018, v. 46, n. 19, p. 10184, doi. 10.1093/nar/gky778
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RGG-box in hnRNPA1 specifically recognizes the telomere G-quadruplex DNA and enhances the G-quadruplex unfolding ability of UP1 domain.
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- Nucleic Acids Research, 2018, v. 46, n. 19, p. 10246, doi. 10.1093/nar/gky854
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RbpA relaxes promoter selectivity of M. tuberculosis RNA polymerase.
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- Nucleic Acids Research, 2018, v. 46, n. 19, p. 10106, doi. 10.1093/nar/gky714
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More is not always better: finding the right trade-off between affinity and selectivity of a G-quadruplex ligand.
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- Nucleic Acids Research, 2018, v. 46, n. 19, p. e115, doi. 10.1093/nar/gky607
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A phosphate-targeted dinuclear Cu(II) complex combining major groove binding and oxidative DNA cleavage.
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- Nucleic Acids Research, 2018, v. 46, n. 19, p. 9918, doi. 10.1093/nar/gky806
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Pancreatic β-cell tRNA hypomethylation and fragmentation link TRMT10A deficiency with diabetes.
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- Nucleic Acids Research, 2018, v. 46, n. 19, p. 10302, doi. 10.1093/nar/gky839
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The OB-fold proteins of the Trypanosoma brucei editosome execute RNA-chaperone activity.
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- Nucleic Acids Research, 2018, v. 46, n. 19, p. 10353, doi. 10.1093/nar/gky668
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Nucleolar residence of the seckel syndrome protein TRAIP is coupled to ribosomal DNA transcription.
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- Nucleic Acids Research, 2018, v. 46, n. 19, p. 10119, doi. 10.1093/nar/gky775
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Rapid high-resolution measurement of DNA replication timing by droplet digital PCR.
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- Nucleic Acids Research, 2018, v. 46, n. 19, p. e112, doi. 10.1093/nar/gky590
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Codon-specific effects of tRNA anticodon loop modifications on translational misreading errors in the yeast Saccharomyces cerevisiae.
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- Nucleic Acids Research, 2018, v. 46, n. 19, p. 10331, doi. 10.1093/nar/gky664
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Molecular mechanisms for dynamic regulation of N1 riboswitch by aminoglycosides.
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- Nucleic Acids Research, 2018, v. 46, n. 19, p. 9960, doi. 10.1093/nar/gky833
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Misfolding of a DNAzyme for ultrahigh sodium selectivity over potassium.
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- Nucleic Acids Research, 2018, v. 46, n. 19, p. 10262, doi. 10.1093/nar/gky807
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MIR100 host gene-encoded lncRNAs regulate cell cycle by modulating the interaction between HuR and its target mRNAs.
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- Nucleic Acids Research, 2018, v. 46, n. 19, p. 10405, doi. 10.1093/nar/gky696
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MetClo: methylase-assisted hierarchical DNA assembly using a single type IIS restriction enzyme.
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- Nucleic Acids Research, 2018, v. 46, n. 19, p. e113, doi. 10.1093/nar/gky596
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Mechanistic insights into histone deposition and nucleosome assembly by the chromatin assembly factor-1.
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- Nucleic Acids Research, 2018, v. 46, n. 19, p. 9907, doi. 10.1093/nar/gky823
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Identification of clustered organellar short (cos) RNAs and of a conserved family of organellar RNA-binding proteins, the heptatricopeptide repeat proteins, in the malaria parasite.
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- Nucleic Acids Research, 2018, v. 46, n. 19, p. 10417, doi. 10.1093/nar/gky710
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A limited number of double-strand DNA breaks is sufficient to delay cell cycle progression.
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- Nucleic Acids Research, 2018, v. 46, n. 19, p. 10132, doi. 10.1093/nar/gky786
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High-resolution analysis of the pneumococcal transcriptome under a wide range of infection-relevant conditions.
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- Nucleic Acids Research, 2018, v. 46, n. 19, p. 9990, doi. 10.1093/nar/gky750
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In vivo cleavage rules and target repertoire of RNase III in Escherichia coli.
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- Nucleic Acids Research, 2018, v. 46, n. 19, p. 10530, doi. 10.1093/nar/gky816
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Cancer-associated mutations of histones H2B, H3.1 and H2A.Z.1 affect the structure and stability of the nucleosome.
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- Nucleic Acids Research, 2018, v. 46, n. 19, p. 10007, doi. 10.1093/nar/gky661
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Mb- and FnCpf1 nucleases are active in mammalian cells: activities and PAM preferences of four wild-type Cpf1 nucleases and of their altered PAM specificity variants.
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- Nucleic Acids Research, 2018, v. 46, n. 19, p. 10272, doi. 10.1093/nar/gky815
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FACER: comprehensive molecular and functional characterization of epigenetic chromatin regulators.
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- Nucleic Acids Research, 2018, v. 46, n. 19, p. 10019, doi. 10.1093/nar/gky679
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The interplay between the Argonaute proteins Piwi and Aub within Drosophila germarium is critical for oogenesis, piRNA biogenesis and TE silencing.
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- Nucleic Acids Research, 2018, v. 46, n. 19, p. 10052, doi. 10.1093/nar/gky695
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Highly efficient genome editing via CRISPR–Cas9 in human pluripotent stem cells is achieved by transient BCL-XL overexpression.
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- Nucleic Acids Research, 2018, v. 46, n. 19, p. 10195, doi. 10.1093/nar/gky804
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A glutamine riboswitch is a key element for the regulation of glutamine synthetase in cyanobacteria.
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- Nucleic Acids Research, 2018, v. 46, n. 19, p. 10082, doi. 10.1093/nar/gky709
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Fluorescence spectroscopic detection and measurement of single telomere molecules.
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- Nucleic Acids Research, 2018, v. 46, n. 19, p. e117, doi. 10.1093/nar/gky627
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How bacterial xenogeneic silencer rok distinguishes foreign from self DNA in its resident genome.
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- Nucleic Acids Research, 2018, v. 46, n. 19, p. 10514, doi. 10.1093/nar/gky836
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