Works matching IS 02724391 AND DT 2024 AND VI 85 AND IP 4

Results: 21

SEP‐363856 exerts neuroprotection through the PI3K/AKT/GSK‐3β signaling pathway in a dual‐hit neurodevelopmental model of schizophrenia‐like mice.

Published in:

Drug Development Research, 2024, v. 85, n. 4, p. 1, doi. 10.1002/ddr.22225

By:

Li, Mengdie;
Liu, Yunxiao;
Sun, Meng;
Yang, Yating;
Zhang, Ling;
Liu, Yuexia;
Li, Fujin;
Liu, Huanzhong

Publication type:

Article

2‐(Methyl(phenyl)amino)‐N‐(phenyloxyphenyl)acetamide structural motif representing a framework for selective SIRT2 inhibition.

Published in:

Drug Development Research, 2024, v. 85, n. 4, p. 1, doi. 10.1002/ddr.22224

By:

Kaya, Selen Gozde;
Eren, Gokcen;
Massarotti, Alberto;
Bakar‐Ates, Filiz;
Ozkan, Erva;
Gozelle, Mahmut;
Ozkan, Yesim

Publication type:

Article

Validating linalool as a potential drug for breast cancer treatment based on machine learning and molecular docking.

Published in:

Drug Development Research, 2024, v. 85, n. 4, p. 1, doi. 10.1002/ddr.22223

By:

Zhang, Qian;
Chen, Dengfeng

Publication type:

Article

Downregulation of HIGD1B induces mitochondria‐mediated apoptosis in gastric cancer cells by inactivating Akt and ERK pathways.

Published in:

Drug Development Research, 2024, v. 85, n. 4, p. 1, doi. 10.1002/ddr.22221

By:

Chen, Xiangyu;
Sun, Binghua;
Li, Shuai

Publication type:

Article

Vedolizumab in the treatment of Crohn's disease: A promising therapeutic approach.

Published in:

Drug Development Research, 2024, v. 85, n. 4, p. 1, doi. 10.1002/ddr.22220

By:

Zargar, Abrar Ahmad

Publication type:

Article

Oxymatrine attenuates sepsis‐induced inflammation and organ injury via inhibition of HMGB1/RAGE/NF‐κB signaling pathway.

Published in:

Drug Development Research, 2024, v. 85, n. 4, p. 1, doi. 10.1002/ddr.22219

By:

He, Junbing;
Qin, Wanbing;
Jiang, Shusong;
Lin, Yao;
Lin, Yingying;
Yang, Ruoxuan;
Xu, Mingwei;
Liu, Qinghua

Publication type:

Article

New benzimidazole‐oxadiazole derivatives as potent VEGFR‐2 inhibitors: Synthesis, anticancer evaluation, and docking study.

Published in:

Drug Development Research, 2024, v. 85, n. 4, p. 1, doi. 10.1002/ddr.22218

By:

Acar Çevik, Ulviye;
Celik, Ismail;
Görgülü, Şennur;
Şahin Inan, Zeynep Deniz;
Bostancı, Hayrani Eren;
Özkay, Yusuf;
Kaplacıklı, Zafer Asım

Publication type:

Article

Vicinal diaryl pyrazole with tetrazole/urea scaffolds as selective angiotensin converting enzyme‐1/cyclooxygenase‐2 inhibitors: Design, synthesis, anti‐hypertensive, anti‐fibrotic, and anti‐inflammatory.

Published in:

Drug Development Research, 2024, v. 85, n. 4, p. 1, doi. 10.1002/ddr.22217

By:

Fadaly, Wael A. A.;
Elshaier, Yaseen A. M. M.;
Ali, Fares E. M.;
El‐Bahrawy, Ali H.;
Abdellatif, Khaled R. A.;
Nemr, Mohamed T. M.

Publication type:

Article

Explore new quinoxaline pharmacophore tethered sulfonamide fragments as in vitro α‐glucosidase, α‐amylase, and acetylcholinesterase inhibitors with ADMET and molecular modeling simulation.

Published in:

Drug Development Research, 2024, v. 85, n. 4, p. 1, doi. 10.1002/ddr.22216

By:

Ragab, Ahmed;
Salem, Mohamed A.;
Ammar, Yousry A.;
Aboulthana, Wael M.;
Helal, Mohamed H.;
Abusaif, Moustafa S.

Publication type:

Article

Glucosyltriazole amphiphile treatment attenuates breast cancer by modulating the AMPK signaling.

Published in:

Drug Development Research, 2024, v. 85, n. 4, p. 1, doi. 10.1002/ddr.22215

By:

Chouhan, Neeraj Kumar;
Eedara, Abhisheik;
Talati, Mamta N.;
Ambadipudi, Sudha S. S. S. S.;
Andugulapati, Sai Balaji;
Pabbaraja, Srihari

Publication type:

Article

Synthesis of new N‐(5,6‐methylenedioxybenzothiazole‐2‐yl)‐2‐[(substituted)thio/piperazine]acetamide/propanamide derivatives and evaluation of their AChE, BChE, and BACE‐1 inhibitory activities.

Published in:

Drug Development Research, 2024, v. 85, n. 4, p. 1, doi. 10.1002/ddr.22214

By:

Tutuş, Beyzanur;
Kaya, Aybüke Züleyha;
Baz, Yonca;
Evren, Asaf Evrim;
Sağlik Özkan, Begüm Nurpelin;
Yurttaş, Leyla

Publication type:

Article

Asprosin aggravates nonalcoholic fatty liver disease via inflammation and lipid metabolic disturbance mediated by reactive oxygen species.

Published in:

Drug Development Research, 2024, v. 85, n. 4, p. 1, doi. 10.1002/ddr.22213

By:

Wang, Chaowen;
Zeng, Wenjing;
Wang, Li;
Xiong, Xiaowei;
Chen, Sheng;
Huang, Qianqian;
Zeng, Guohua;
Huang, Qiren

Publication type:

Article

Newly synthesized acridone derivatives targeting lung cancer: A toxicity and xenograft model study.

Published in:

Drug Development Research, 2024, v. 85, n. 4, p. 1, doi. 10.1002/ddr.22212

By:

Bhusare, Nilam;
Yadav, Tanuja;
Nandave, Mukesh;
Gadade, Amruta;
Dighe, Vikas;
Peters, Godefridus J.;
Kumar, Maushmi S.;
Yergeri, Mayur C.

Publication type:

Article

Repurposing of drugs against bacterial infections: A pharmacovigilance‐based data mining approach.

Published in:

Drug Development Research, 2024, v. 85, n. 4, p. 1, doi. 10.1002/ddr.22211

By:

Ohra, Simran;
Sharma, Ruchika;
Kumar, Anoop

Publication type:

Article

Modafinil lightens apoptosis and inflammatory response in hepatic ischemia‐reperfusion injury through inactivation of TLR9/Myd88/p38 signaling.

Published in:

Drug Development Research, 2024, v. 85, n. 4, p. 1, doi. 10.1002/ddr.22210

By:

Zhang, Tairan;
Wang, Xidong

Publication type:

Article

Hesperidin, vanillic acid, and sinapic acid attenuate atorvastatin‐induced mitochondrial dysfunction via inhibition of mitochondrial swelling and maintenance of mitochondrial function in pancreas isolated mitochondria.

Published in:

Drug Development Research, 2024, v. 85, n. 4, p. 1, doi. 10.1002/ddr.22199

By:

Salimi, Ahmad;
Khezri, Saleh;
Vahabzadeh, Zoleikhah;
Rajabi, Paria;
Samimi, Rojin;
Adhami, Vahed

Publication type:

Article

Issue Information.

Published in:: Drug Development Research, 2024, v. 85, n. 4, p. 1, doi. 10.1002/ddr.22209
Publication type:: Article

Pantoprazole suppresses carcinogenesis and growth of hepatocellular carcinoma by inhibiting glycolysis and Na<sup>+</sup>/H<sup>+</sup> exchange.

Published in:

Drug Development Research, 2024, v. 85, n. 4, p. 1, doi. 10.1002/ddr.22198

By:

Jin, Hai;
Wen, Guorong;
Zhu, Jiaxing;
Liu, Jielong;
Li, Jingguo;
Yao, Shun;
Zhao, Zhenglan;
Dong, Zhiqi;
Zhang, Xue;
An, Jiaxing;
Liu, Xuemei;
Tuo, Biguang

Publication type:

Article

Design and synthesis of novel tetrabromophthalimide derivatives as potential tubulin inhibitors endowed with apoptotic induction for cancer treatment.

Published in:

Drug Development Research, 2024, v. 85, n. 4, p. 1, doi. 10.1002/ddr.22197

By:

Abdel‐Motaal, Marwa;
Aldakhili, Dalal A.;
Abo Elmaaty, Ayman;
Sharaky, Marwa;
Mourad, Mai A. E.;
Alzahrani, Abdullah Y. A.;
Mohamed, Nadia A.;
Al‐Karmalawy, Ahmed A.

Publication type:

Article

Apigenin alleviates doxorubicin‐induced myocardial pyroptosis by inhibiting glycogen synthase kinase‐3β in vitro and in vivo.

Published in:

Drug Development Research, 2024, v. 85, n. 4, p. 1, doi. 10.1002/ddr.22196

By:

Wang, Feng;
Yan, Xinxin;
Yue, Anna;
Zhang, Kaiyu;
Li, Ping;
Xu, Jingyi;
Sun, Kangyun;
Zhang, Qian;
Li, Yuan

Publication type:

Article

Unveiling the potential of antisense oligonucleotides: Mechanisms, therapies, and safety insights.

Published in:

Drug Development Research, 2024, v. 85, n. 4, p. 1, doi. 10.1002/ddr.22187

By:

Ersöz, Edanur;
Demir‐Dora, Devrim

Publication type:

Article