Works matching IS 02724391 AND DT 2024 AND VI 85 AND IP 1

Results: 37

Costunolide attenuates high‐fat diet‐induced inflammation and oxidative stress in non‐alcoholic fatty liver disease.

Published in:

Drug Development Research, 2024, v. 85, n. 1, p. 1, doi. 10.1002/ddr.22150

By:

Wang, Jiong;
Jin, Bo;
Chen, Yanghao;
Chen, Yi;
Zuo, Wei;
Huang, Lijiang;
Lin, Jianjun;
Jiang, Yongsheng;
Xie, Longteng;
Lian, Xiang;
Wang, Yi

Publication type:

Article

Design and synthesis of vancomycin‐functionalized ZnFe2O4 nanoparticles as an effective antibacterial agent against methicillin‐resistant Staphylococcus aureus.

Published in:

Drug Development Research, 2024, v. 85, n. 1, p. 1, doi. 10.1002/ddr.22148

By:

Akbari, Minoo;
Rezayan, Ali Hossein;
Rastegar, Hossein;
Alebouyeh, Mahmoud;
Yahyaei, Mohammad

Publication type:

Article

Exploring the potential of radiolabeled duramycin as an infection imaging probe.

Published in:

Drug Development Research, 2024, v. 85, n. 1, p. 1, doi. 10.1002/ddr.22138

By:

Kumar, Anuj;
Mitra, Jyotsna Bhatt;
Khatoon, Elina;
Pramanik, Aparna;
Sharma, Rohit K.;
Chandak, Ashok;
Rakshit, Sutapa;
Mukherjee, Archana

Publication type:

Article

CALCRL knockdown suppresses cancer stemness and chemoresistance in acute myeloid leukemia with FLT3‐ITD and DNM3TA‐R882 double mutations.

Published in:

Drug Development Research, 2024, v. 85, n. 1, p. 1, doi. 10.1002/ddr.22137

By:

Tang, Shanhao;
Zhu, Huiling;
Sheng, Lixia;
Mu, Qitian;
Wang, Yi;
Xu, Kaihong;
Zhou, Miao;
Xu, Zhijuan;
Wu, An;
Ouyang, Guifang

Publication type:

Article

FGF12 restrains mitochondria‐dependent ferroptosis in doxorubicin‐induced cardiomyocytes through the activation of FGFR1/AMPK/NRF2 signaling.

Published in:

Drug Development Research, 2024, v. 85, n. 1, p. 1, doi. 10.1002/ddr.22149

By:

Tian, Ge;
Li, Jing;
Wang, Wenjie;
Zhou, Lina

Publication type:

Article

Cover Image, Volume 85, Issue 1.

Published in:

Drug Development Research, 2024, v. 85, n. 1, p. 1, doi. 10.1002/ddr.22176

By:

Eschbach, Judith;
Wagner, Alain;
Beahr, Corinne;
Bekel, Akkiz;
Korganow, Anne‐Sophie;
Quartier, Angelique;
Peter, Jean‐Christophe;
Eftekhari, Pierre

Publication type:

Article

Early investigation of a novel SI306 theranostic prodrug for glioblastoma treatment.

Published in:

Drug Development Research, 2024, v. 85, n. 1, p. 1, doi. 10.1002/ddr.22158

By:

Vagaggini, Chiara;
Petroni, Debora;
D'Agostino, Ilaria;
Poggialini, Federica;
Cavallini, Chiara;
Cianciusi, Annarita;
Salis, Annalisa;
D'Antona, Lucia;
Francesconi, Valeria;
Manetti, Fabrizio;
Damonte, Gianluca;
Musumeci, Francesca;
Menichetti, Luca;
Dreassi, Elena;
Carbone, Anna;
Schenone, Silvia

Publication type:

Article

Influence of β‐catenin signaling on neurogenesis in neuropsychiatric disorders: Anxiety and depression.

Published in:

Drug Development Research, 2024, v. 85, n. 1, p. 1, doi. 10.1002/ddr.22157

By:

El‐Kadi, Rana A.;
AbdelKader, Noha F.;
Zaki, Hala F.;
Kamel, Ahmed S.

Publication type:

Article

Bazedoxifene analogs as potential WDHD1 degraders and antitumor agents: Synthesis, evaluation and molecular dynamics simulation studies.

Published in:

Drug Development Research, 2024, v. 85, n. 1, p. 1, doi. 10.1002/ddr.22155

By:

Chen, Leyuan;
Liu, Gaiting;
Meng, Fancui;
shi, Yu;
Fang, Zhennan;
Peng, Zhenyu;
Wang, Manjiang;
Gou, Wenfeng;
Hou, Wenbin;
Li, Yiliang

Publication type:

Article

Tri‐substituted 1,3,5‐triazine‐based analogs as effective HIV‐1 non‐nucleoside reverse transcriptase inhibitors (NNRTIs): A systematic review.

Published in:

Drug Development Research, 2024, v. 85, n. 1, p. 1, doi. 10.1002/ddr.22154

By:

Khalifa, Zebabanu;
Patel, Amit B.

Publication type:

Article

N‐Substituted piperazine‐coupled imidazo[2,1‐b]thiazoles as inhibitors of Mycobacterium tuberculosis: Synthesis, evaluation, and docking studies.

Published in:

Drug Development Research, 2024, v. 85, n. 1, p. 1, doi. 10.1002/ddr.22153

By:

Chirra, Nagaraju;
Abburi, Naga Pranathi;
Rekha, Estharla Madhu;
Pedapati, Ravi kumar;
Bollikanda, Rakesh Kumar;
Murahari, Manikanta;
Sriram, Dharmarajan;
Sridhar, Balasubramanian;
Kantevari, Srinivas

Publication type:

Article

Dendrobine regulates STAT3 to attenuate mitochondrial dysfunction and senescence in vascular endothelial cells triggered by oxidized low‐density lipoprotein.

Published in:

Drug Development Research, 2024, v. 85, n. 1, p. 1, doi. 10.1002/ddr.22152

By:

Xia, Jia;
Chen, Jingyi;
Xing, Xinyue;
Meng, Jing;
Song, Xiaoying;
Lou, Danfei

Publication type:

Article

Drug upgrade: A complete methodology from old drug to new chemical entities using Nematic Protein Organization Technique.

Published in:

Drug Development Research, 2024, v. 85, n. 1, p. 1, doi. 10.1002/ddr.22151

By:

Eschbach, Judith;
Wagner, Alain;
Beahr, Corinne;
Bekel, Akkiz;
Korganow, Anne‐Sophie;
Quartier, Angelique;
Peter, Jean‐Christophe;
Eftekhari, Pierre

Publication type:

Article

68Ga‐labeled, imatinib encapsulated, theranostic liposomes: Formulation, characterization, and in vitro evaluation of anticancer activity.

Published in:

Drug Development Research, 2024, v. 85, n. 1, p. 1, doi. 10.1002/ddr.22136

By:

Karpuz, Merve;
Ozgenc, Emre;
Oner, Ezgi;
Atlihan‐Gundogdu, Evren;
Burak, Zeynep

Publication type:

Article

Novel sulfonamide‐phosphonate conjugates as carbonic anhydrase isozymes inhibitors.

Published in:

Drug Development Research, 2024, v. 85, n. 1, p. 1, doi. 10.1002/ddr.22135

By:

Bekheit, Mohamed S.;
Sabry, Eman;
Mohamed, Hanan A.;
Ewies, Ewies F.;
Kariuki, Benson M.;
Fouad, Marwa A.;
Vullo, Daniela;
Supuran, Claudiu T.

Publication type:

Article

Development and evaluation of multi‐functionalized sialic acid conjugated asiatic acid nanoconstruct to mitigate cognitive deficits in Alzheimer's disease.

Published in:

Drug Development Research, 2024, v. 85, n. 1, p. 1, doi. 10.1002/ddr.22146

By:

Halder, Tripti;
Saha, Bijit;
Dhas, Namdev;
Acharya, Sanjeev;
Acharya, Niyati

Publication type:

Article

Combined chemotherapy of zoledronic acid and pamidronate in the treatment of bone metastases from nonsmall cell lung cancer and the effects on pain stress and bone metabolic indices.

Published in:

Drug Development Research, 2024, v. 85, n. 1, p. 1, doi. 10.1002/ddr.22147

By:

Huang, Kun;
Tang, Xiao;
Tang, Fang

Publication type:

Article

Proteolysis‐targeting chimeras in antiviral therapy: Leveraging influenza virus and exosome‐mediated delivery for targeted protein degradation and therapeutic advancements.

Published in:

Drug Development Research, 2024, v. 85, n. 1, p. 1, doi. 10.1002/ddr.22145

By:

Mukerjee, Nobendu;
Maitra, Swastika;
Sharma, Rohit

Publication type:

Article

2‐Thioxo‐3,4‐dihydropyrimidine and thiourea endowed with sulfonamide moieties as dual EGFRT790M and VEGFR‐2 inhibitors: Design, synthesis, docking, and anticancer evaluations.

Published in:

Drug Development Research, 2024, v. 85, n. 1, p. 1, doi. 10.1002/ddr.22143

By:

El‐Gaby, Mohamed S. A.;
Abdel Reheim, Mohamed A. M.;
Akrim, Zuhir S. M.;
Naguib, Bassem H.;
Saleh, Nashwa M.;
El‐Adasy, Abu Bakr A. A. M.;
El‐Adl, Khaled;
Mohamady, Samy

Publication type:

Article

Issue Information.

Published in:: Drug Development Research, 2024, v. 85, n. 1, p. 1, doi. 10.1002/ddr.22144
Publication type:: Article

AKR1C3 silencing inhibits autophagy‐dependent glycolysis in thyroid cancer cells by inactivating ERK signaling.

Published in:

Drug Development Research, 2024, v. 85, n. 1, p. 1, doi. 10.1002/ddr.22142

By:

Gao, Ying;
Tao, Weijie;
Wang, Shoujun;
Duan, Ran;
Zhang, Zhendong

Publication type:

Article

Mechanism of gambogic acid repressing invasion and metastasis of colorectal cancer by regulating macrophage polarization via tumor cell‐derived extracellular vesicle‐shuttled miR‐21.

Published in:

Drug Development Research, 2024, v. 85, n. 1, p. 1, doi. 10.1002/ddr.22141

By:

Li, You;
Liao, Wenqi;
Huang, Wei;
Liu, Fenglin;
Ma, Lin;
Qian, Xiaoping

Publication type:

Article

Everolimus inhibits hepatoblastoma by inducing autophagy‐dependent ferroptosis.

Published in:

Drug Development Research, 2024, v. 85, n. 1, p. 1, doi. 10.1002/ddr.22140

By:

Huang, Haijin;
Yan, Jinlong;
Xu, Xianyun;
Feng, Yanping;
Liu, Haijin;
Liu, Jianping;
Xie, Mingfeng;
Chen, Leifeng;
Xiang, Deng;
Peng, Wei;
Zeng, Linshan;
Zeng, Yong;
Chen, Feng;
Zhang, Shouhua;
Liu, Qian

Publication type:

Article

Comprehensive characterization and preclinical assessment of an imidazopyridine‐based anticancer lead molecule.

Published in:

Drug Development Research, 2024, v. 85, n. 1, p. 1, doi. 10.1002/ddr.22139

By:

Bulbule, Ratik Ramesh;
Jadav, Tarang;
Rajput, Niraj;
Das, Rudradip;
Chatterjee, Deep Rohan;
Shard, Amit;
Sengupta, Pinaki

Publication type:

Article

Anti‐allodynic and anti‐hyperalgesic activity of (±)‐licarin A in neuropathic rats via NO‐cyclic‐GMP‐ATP‐sensitive K+ channel pathway.

Published in:

Drug Development Research, 2024, v. 85, n. 1, p. 1, doi. 10.1002/ddr.22134

By:

Hernández‐Vázquez, Liliana;
Colín‐Martínez, Brian;
Lara‐Ruíz, María Guadalupe;
Cordova‐Alonso, Beatriz;
González‐Morales, Estefanía;
Godínez‐Chaparro, Beatriz

Publication type:

Article

Design, synthesis of novel chromene‐based scaffolds targeting hepatocellular carcinoma: Cell cycle arrest, cytotoxic effect against resistant cancer cells, apoptosis induction, and c‐Src inhibition.

Published in:

Drug Development Research, 2024, v. 85, n. 1, p. 1, doi. 10.1002/ddr.22133

By:

Abdelall, Eman K. A.;
Elshemy, Heba A. H.;
Labib, Madlen B.;
Mohamed, Fatma E. A.

Publication type:

Article

Covalent inhibitors: An ambitious approach for the discovery of newer oncotherapeutics.

Published in:

Drug Development Research, 2024, v. 85, n. 1, p. 1, doi. 10.1002/ddr.22132

By:

Cheke, Rameshwar S.;
Kharkar, Prashant S.

Publication type:

Article

Heat‐shock protein A12A attenuates oxygen‐glucose deprivation/reoxygenation‐induced human brain microvascular endothelial cell dysfunction via PGC‐1α/SIRT3 pathway.

Published in:

Drug Development Research, 2024, v. 85, n. 1, p. 1, doi. 10.1002/ddr.22130

By:

Li, Jun;
Shen, Shouyin;
Shen, Haiyan

Publication type:

Article

Discovery of N‐(phenylsulfonyl)thiazole‐2‐carboxamides as potent α‐glucosidase inhibitors.

Published in:

Drug Development Research, 2024, v. 85, n. 1, p. 1, doi. 10.1002/ddr.22128

By:

Liu, Jun;
Li, Jia‐Hao;
Zhao, Si‐Yu;
Chang, Yi‐Qun;
Chen, Qiu‐Xian;
Wu, Wen‐Fu;
Jiao, Shu‐Meng;
Xiao, Haichuan;
Zhang, Qiang;
Zhao, Jian‐Fu;
Xu, Jun;
Sun, Ping‐Hua

Publication type:

Article

Design, synthesis, and in‐silico study of novel triarylethylene analogs with dual anti‐estrogenic and serotonergic activity.

Published in:

Drug Development Research, 2024, v. 85, n. 1, p. 1, doi. 10.1002/ddr.22127

By:

Mostafa, Tammy;
Albeir, Miriam;
Wober, Jannette;
Abadi, Ashraf;
Salama, Ismail;
Ahmed, Nermin S.

Publication type:

Article

Function of proprotein convertase subtilisin/kexin type 9 and its role in central nervous system diseases: An update on clinical evidence.

Published in:

Drug Development Research, 2024, v. 85, n. 1, p. 1, doi. 10.1002/ddr.22131

By:

Zhu, Xiao‐Bin;
Xu, Yao‐Yao;
Li, Liu‐Cheng;
Sun, Jia‐Bin;
Wang, Yu‐Zhen;
Chen, Jie;
Wang, Chen;
Zhang, Su;
Jin, Liang‐Yan

Publication type:

Article

Investigation of the activity of a novel tropolone in osteosarcoma.

Published in:

Drug Development Research, 2024, v. 85, n. 1, p. 1, doi. 10.1002/ddr.22129

By:

Haney, Staci L.;
Feng, Dan;
Kollala, Sai Sundeep;
Chhonker, Yashpal S.;
Varney, Michelle L.;
Williams, Jacob T.;
Ford, James B.;
Murry, Daryl J.;
Holstein, Sarah A.

Publication type:

Article

Medicinal polypharmacology: Exploration and exploitation of the polypharmacolome in modern drug development.

Published in:

Drug Development Research, 2024, v. 85, n. 1, p. 1, doi. 10.1002/ddr.22125

By:

Stefan, Sven Marcel;
Rafehi, Muhammad

Publication type:

Article

Nitroimidazole derivatives potentiated against tumor hypoxia: Design, synthesis, antitumor activity, molecular docking study, and QSAR study.

Published in:

Drug Development Research, 2024, v. 85, n. 1, p. 1, doi. 10.1002/ddr.22126

By:

Almatary, Aya M.;
El Husseiny, Walaa M.;
Selim, Khalid B.;
Eisa, Hassan M. H.

Publication type:

Article

AS602801 treatment suppresses breast cancer metastasis to the brain by interfering with gap‐junction communication by regulating Cx43 expression.

Published in:

Drug Development Research, 2024, v. 85, n. 1, p. 1, doi. 10.1002/ddr.22124

By:

Yang, Zhigang;
Yang, Liguo;
Zhang, Jun;
Qian, Chenzeyue;
Zhao, Yi

Publication type:

Article

Indole‐based aryl sulfides target the cell wall of Staphylococcus aureus without detectable resistance.

Published in:

Drug Development Research, 2024, v. 85, n. 1, p. 1, doi. 10.1002/ddr.22123

By:

Lavekar, Aditya G.;
Thakare, Ritesh;
Saima;
Equbal, Danish;
Chopra, Sidharth;
Sinha, Arun K.

Publication type:

Article

A growth‐based assay using fluorescent protein emission to screen for S‐adenosylmethionine synthetase inhibitors.

Published in:

Drug Development Research, 2024, v. 85, n. 1, p. 1, doi. 10.1002/ddr.22122

By:

Viola, Ronald E.;
Parungao, Gwenn G.;
Blumenthal, Robert M.

Publication type:

Article

Works matching IS 02724391 AND DT 2024 AND VI 85 AND IP 1

Costunolide attenuates high‐fat diet‐induced inflammation and oxidative stress in non‐alcoholic fatty liver disease.

Design and synthesis of vancomycin‐functionalized ZnFe<sub>2</sub>O<sub>4</sub> nanoparticles as an effective antibacterial agent against methicillin‐resistant Staphylococcus aureus.

Exploring the potential of radiolabeled duramycin as an infection imaging probe.

CALCRL knockdown suppresses cancer stemness and chemoresistance in acute myeloid leukemia with FLT3‐ITD and DNM3TA‐R882 double mutations.

FGF12 restrains mitochondria‐dependent ferroptosis in doxorubicin‐induced cardiomyocytes through the activation of FGFR1/AMPK/NRF2 signaling.

Cover Image, Volume 85, Issue 1.

Early investigation of a novel SI306 theranostic prodrug for glioblastoma treatment.

Influence of β‐catenin signaling on neurogenesis in neuropsychiatric disorders: Anxiety and depression.

Bazedoxifene analogs as potential WDHD1 degraders and antitumor agents: Synthesis, evaluation and molecular dynamics simulation studies.

Tri‐substituted 1,3,5‐triazine‐based analogs as effective HIV‐1 non‐nucleoside reverse transcriptase inhibitors (NNRTIs): A systematic review.

N‐Substituted piperazine‐coupled imidazo[2,1‐b]thiazoles as inhibitors of Mycobacterium tuberculosis: Synthesis, evaluation, and docking studies.

Dendrobine regulates STAT3 to attenuate mitochondrial dysfunction and senescence in vascular endothelial cells triggered by oxidized low‐density lipoprotein.

Drug upgrade: A complete methodology from old drug to new chemical entities using Nematic Protein Organization Technique.

<sup>68</sup>Ga‐labeled, imatinib encapsulated, theranostic liposomes: Formulation, characterization, and in vitro evaluation of anticancer activity.

Novel sulfonamide‐phosphonate conjugates as carbonic anhydrase isozymes inhibitors.

Development and evaluation of multi‐functionalized sialic acid conjugated asiatic acid nanoconstruct to mitigate cognitive deficits in Alzheimer's disease.

Combined chemotherapy of zoledronic acid and pamidronate in the treatment of bone metastases from nonsmall cell lung cancer and the effects on pain stress and bone metabolic indices.

Proteolysis‐targeting chimeras in antiviral therapy: Leveraging influenza virus and exosome‐mediated delivery for targeted protein degradation and therapeutic advancements.

2‐Thioxo‐3,4‐dihydropyrimidine and thiourea endowed with sulfonamide moieties as dual EGFR<sup>T790M</sup> and VEGFR‐2 inhibitors: Design, synthesis, docking, and anticancer evaluations.

Issue Information.

AKR1C3 silencing inhibits autophagy‐dependent glycolysis in thyroid cancer cells by inactivating ERK signaling.

Mechanism of gambogic acid repressing invasion and metastasis of colorectal cancer by regulating macrophage polarization via tumor cell‐derived extracellular vesicle‐shuttled miR‐21.

Everolimus inhibits hepatoblastoma by inducing autophagy‐dependent ferroptosis.

Comprehensive characterization and preclinical assessment of an imidazopyridine‐based anticancer lead molecule.

Anti‐allodynic and anti‐hyperalgesic activity of (±)‐licarin A in neuropathic rats via NO‐cyclic‐GMP‐ATP‐sensitive K+ channel pathway.

Design, synthesis of novel chromene‐based scaffolds targeting hepatocellular carcinoma: Cell cycle arrest, cytotoxic effect against resistant cancer cells, apoptosis induction, and c‐Src inhibition.

Covalent inhibitors: An ambitious approach for the discovery of newer oncotherapeutics.

Heat‐shock protein A12A attenuates oxygen‐glucose deprivation/reoxygenation‐induced human brain microvascular endothelial cell dysfunction via PGC‐1α/SIRT3 pathway.

Discovery of N‐(phenylsulfonyl)thiazole‐2‐carboxamides as potent α‐glucosidase inhibitors.

Design, synthesis, and in‐silico study of novel triarylethylene analogs with dual anti‐estrogenic and serotonergic activity.

Function of proprotein convertase subtilisin/kexin type 9 and its role in central nervous system diseases: An update on clinical evidence.

Investigation of the activity of a novel tropolone in osteosarcoma.

Medicinal polypharmacology: Exploration and exploitation of the polypharmacolome in modern drug development.

Nitroimidazole derivatives potentiated against tumor hypoxia: Design, synthesis, antitumor activity, molecular docking study, and QSAR study.

AS602801 treatment suppresses breast cancer metastasis to the brain by interfering with gap‐junction communication by regulating Cx43 expression.

Indole‐based aryl sulfides target the cell wall of Staphylococcus aureus without detectable resistance.

A growth‐based assay using fluorescent protein emission to screen for S‐adenosylmethionine synthetase inhibitors.