Works matching IS 02646021 AND DT 2021 AND VI 478 AND IP 13

Results: 20

Mapping the substrate specificity of the Plasmodium M1 and M17 aminopeptidases.

Published in:

Biochemical Journal, 2021, v. 478, n. 13, p. 2697, doi. 10.1042/BCJ20210172

By:

Malcolm, Tess R.;
Swiderska, Karolina W.;
Hayes, Brooke K.;
Webb, Chaille T.;
Drag, Marcin;
Drinkwater, Nyssa;
McGowan, Sheena

Publication type:

Article

Identifying SARS-CoV-2 antiviral compounds by screening for small molecule inhibitors of nsp14/ nsp10 exoribonuclease.

Published in:

Biochemical Journal, 2021, v. 478, n. 13, p. 2445, doi. 10.1042/BCJ20210198

By:

Canal, Berta;
McClure, Allison W.;
Curran, Joseph F.;
Wu, Mary;
Ulferts, Rachel;
Weissmann, Florian;
Jingkun Zeng;
Bertolin, Agustina P.;
Milligan, Jennifer C.;
Basu, Souradeep;
Drury, Lucy S.;
Deegan, Tom D.;
Fujisawa, Ryo;
Roberts, Emma L.;
Basier, Clovis;
Labib, Karim;
Beale, Rupert;
Howell, Michael;
Diffley, John F. X.

Publication type:

Article

Characterization of caspase-7 interaction with RNA.

Published in:

Biochemical Journal, 2021, v. 478, n. 13, p. 2681, doi. 10.1042/BCJ20210366

By:

Desroches, Alexandre;
Denault, Jean-Bernard

Publication type:

Article

Author’s overview: identifying SARS-CoV-2 antiviral compounds.

Published in:

Biochemical Journal, 2021, v. 478, n. 13, p. 2533, doi. 10.1042/BCJ20210426

By:

Diffley, John F. X.

Publication type:

Article

Structural and calorimetric studies reveal specific determinants for the binding of a high-affinity NLS to mammalian importin-alpha.

Published in:

Biochemical Journal, 2021, v. 478, n. 13, p. 2715, doi. 10.1042/BCJ20210401

By:

de Oliveira, Hamine C.;
da Silva, Tainá D.;
Salvador, Guilherme H. M.;
Moraes, Ivan R.;
Fukuda, Cíntia A.;
de Barros, Andrea C.;
Fontes, Marcos R. M.

Publication type:

Article

The interplay of self-assembly and target binding in centrin 1 from Toxoplasma gondii.

Published in:

Biochemical Journal, 2021, v. 478, n. 13, p. 2571, doi. 10.1042/BCJ20210295

By:

Conter, Carolina;
Bombardi, Luca;
Pedretti, Marco;
Favretto, Filippo;
Matteo, Adele Di;
Dominici, Paola;
Astegno, Alessandra

Publication type:

Article

SMCHD1’s ubiquitin-like domain is required for N-terminal dimerization and chromatin localization.

Published in:

Biochemical Journal, 2021, v. 478, n. 13, p. 2555, doi. 10.1042/BCJ20210278

By:

Gurzau, Alexandra D.;
Horne, Christopher R.;
Mok, Yee-Foong;
Iminitoff, Megan;
Willson, Tracy A.;
Young, Samuel N.;
Blewitt, Marnie E.;
Murphy, James M.

Publication type:

Article

Insulin rapidly increases skeletal muscle mitochondrial ADP sensitivity in the absence of a high lipid environment.

Published in:

Biochemical Journal, 2021, v. 478, n. 13, p. 2539, doi. 10.1042/BCJ20210264

By:

Brunetta, Henver S.;
Petrick, Heather L.;
Vachon, Bayley;
Nunes, Everson A.;
Holloway, Graham P.

Publication type:

Article

Identifying SARS-CoV-2 antiviral compounds by screening for small molecule inhibitors of Nsp3 papain-like protease.

Published in:

Biochemical Journal, 2021, v. 478, n. 13, p. 2517, doi. 10.1042/BCJ20210244

By:

Chew Theng Lim;
Kang Wei Tan;
Wu, Mary;
Ulferts, Rachel;
Armstrong, Lee A.;
Eiko Ozono;
Drury, Lucy S.;
Milligan, Jennifer C.;
Zeisner, Theresa U.;
Jingkun Zeng;
Weissmann, Florian;
Canal, Berta;
Bineva-Todd, Ganka;
Howell, Michael;
O’Reilly, Nicola;
Beale, Rupert;
Kulathu, Yogesh;
Labib, Karim;
Diffley, John F. X.

Publication type:

Article

An all-out assault on SARS-CoV-2 replication.

Published in:

Biochemical Journal, 2021, v. 478, n. 13, p. 2399, doi. 10.1042/BCJ20210256

By:

Hay, Ronald T.

Publication type:

Article

Identifying SARS-CoV-2 antiviral compounds by screening for small molecule inhibitors of Nsp14 RNA cap methyltransferase.

Published in:

Biochemical Journal, 2021, v. 478, n. 13, p. 2481, doi. 10.1042/BCJ20210219

By:

Basu, Souradeep;
Mak, Tiffany;
Ulferts, Rachel;
Wu, Mary;
Deegan, Tom;
Fujisawa, Ryo;
Kang Wei Tan;
Chew Theng Lim;
Basier, Clovis;
Canal, Berta;
Curran, Joseph F.;
Drury, Lucy S.;
McClure, Allison W.;
Roberts, Emma L.;
Weissmann, Florian;
Zeisner, Theresa U.;
Beale, Rupert;
Cowling, Victoria H.;
Howell, Michael;
Labib, Karim

Publication type:

Article

Identifying SARS-CoV-2 antiviral compounds by screening for small molecule inhibitors of nsp13 helicase.

Published in:

Biochemical Journal, 2021, v. 478, n. 13, p. 2405, doi. 10.1042/BCJ20210201

By:

Jingkun Zeng;
Weissmann, Florian;
Bertolin, Agustina P.;
Posse, Viktor;
Canal, Berta;
Ulferts, Rachel;
Wu, Mary;
Harvey, Ruth;
Hussain, Saira;
Milligan, Jennifer C.;
Roustan, Chloe;
Borg, Annabel;
McCoy, Laura;
Drury, Lucy S.;
Kjaer, Svend;
McCauley, John;
Howell, Michael;
Beale, Rupert;
Diffley, John F. X.

Publication type:

Article

Identifying SARS-CoV-2 antiviral compounds by screening for small molecule inhibitors of nsp12/7/8 RNA-dependent RNA polymerase.

Published in:

Biochemical Journal, 2021, v. 478, n. 13, p. 2425, doi. 10.1042/BCJ20210200

By:

Bertolin, Agustina P.;
Weissmann, Florian;
Jingkun Zeng;
Posse, Viktor;
Milligan, Jennifer C.;
Canal, Berta;
Ulferts, Rachel;
Wu, Mary;
Drury, Lucy S.;
Howell, Michael;
Beale, Rupert;
Diffley, John F. X.

Publication type:

Article

Identifying SARS-CoV-2 antiviral compounds by screening for small molecule inhibitors of nsp15 endoribonuclease.

Published in:

Biochemical Journal, 2021, v. 478, n. 13, p. 2465, doi. 10.1042/bcj20210198

By:

Canal, Berta;
Fujisawa, Ryo;
McClure, Allison W.;
Deegan, Tom D.;
Wu, Mary;
Ulferts, Rachel;
Weissmann, Florian;
Drury, Lucy S.;
Bertolin, Agustina P.;
Jingkun Zeng;
Beale, Rupert;
Howell, Michael;
Labib, Karim;
Diffley, John F. X.

Publication type:

Article

The structures of E. coli NfsA bound to the antibiotic nitrofurantoin; to 1,4-benzoquinone and to FMN.

Published in:

Biochemical Journal, 2021, v. 478, n. 13, p. 2601, doi. 10.1042/BCJ20210160

By:

Day, Martin A.;
Jarrom, David;
Christofferson, Andrew J.;
Graziano, Antonio E.;
Ross Anderson, J. L.;
Searle, Peter F.;
Hyde, Eva I.;
White, Scott A.

Publication type:

Article

Identifying SARS-CoV-2 antiviral compounds by screening for small molecule inhibitors of Nsp5 main protease.

Published in:

Biochemical Journal, 2021, v. 478, n. 13, p. 2499, doi. 10.1042/BCJ20210197

By:

Milligan, Jennifer C.;
Zeisner, Theresa U.;
Papageorgiou, George;
Joshi, Dhira;
Soudy, Christelle;
Ulferts, Rachel;
Wu, Mary;
Chew Theng Lim;
Kang Wei Tan;
Weissmann, Florian;
Canal, Berta;
Fujisawa, Ryo;
Deegan, Tom;
Nagaraj, Hema;
Bineva-Todd, Ganka;
Basier, Clovis;
Curran, Joseph F.;
Howell, Michael;
Beale, Rupert;
Labib, Karim

Publication type:

Article

Inhibitory feedback control of NF-κB signalling in health and disease.

Published in:

Biochemical Journal, 2021, v. 478, n. 13, p. 2619, doi. 10.1042/BCJ20210139

By:

Prescott, Jack A.;
Mitchell, Jennifer P.;
Cook, Simon J.

Publication type:

Article

Correction: Mobility shift-based electrophoresis coupled with fluorescent detection enables realtime enzyme analysis of carbohydrate sulfatase activity.

Published in:

Biochemical Journal, 2021, v. 478, n. 13, p. 2537, doi. 10.1042/bcj-2020-0952_cor

By:

Byrne, Dominic P.;
London, James A.;
Eyers, Patrick A.;
Yates, Edwin A.;
Cartmell, Alan

Publication type:

Article

Structure of an open conformation of T7 DNA polymerase reveals novel structural features regulating primer-template stabilization at the polymerization active site.

Published in:

Biochemical Journal, 2021, v. 478, n. 13, p. 2665, doi. 10.1042/BCJ20200922

By:

Juarez-Quintero, Víctor;
Peralta-Castro, Antolín;
Benítez Cardoza, Claudia G.;
Ellenberger, Tom;
Brieba, Luis G.

Publication type:

Article

Hetero-oligomerization of Bacillus thuringiensis Cry1A proteins enhance binding to the ABCC2 transporter of Spodoptera exigua.

Published in:

Biochemical Journal, 2021, v. 478, n. 13, p. 2589, doi. 10.1042/BCJ20210137

By:

Pinos, Daniel;
Joya, Noelia;
Herrero, Salvador;
Ferré, Juan;
Hernández-Martínez, Patricia

Publication type:

Article