Works matching IS 02614189 AND DT 2025 AND VI 44 AND IP 4

Results: 11

RHEB neddylation by the UBE2F-SAG axis enhances mTORC1 activity and aggravates liver tumorigenesis.

Published in:

EMBO Journal, 2025, v. 44, n. 4, p. 1185, doi. 10.1038/s44318-024-00353-5

By:

Zhang, Fengwu;
Xiong, Xiufang;
Li, Zhijian;
Wang, Haibo;
Wang, Weilin;
Zhao, Yongchao;
Sun, Yi

Publication type:

Article

E3 ubiquitin ligase CHIP facilitates cAMP and cGMP signalling cross-talk by polyubiquitinating PDE9A.

Published in:

EMBO Journal, 2025, v. 44, n. 4, p. 1249, doi. 10.1038/s44318-024-00351-7

By:

Hao, Xiaoyan;
Hu, Zhengwei;
Li, Mengjie;
Zhang, Shuo;
Tang, Mibo;
Hao, Chenwei;
Qi, Shasha;
Liang, Yuanyuan;
Almeida, Michael F;
Smith, Kaitlan;
Zuo, Chunyan;
Feng, Yanmei;
Guo, Mengnan;
Ma, Dongrui;
Li, Shuangjie;
Wang, Zhiyun;
Sun, Yuemeng;
Deng, Zhifen;
Mao, Chengyuan;
Xia, Zongping

Publication type:

Article

A bipartite bacterial virulence factor targets the complement system and neutrophil activation.

Published in:

EMBO Journal, 2025, v. 44, n. 4, p. 1154, doi. 10.1038/s44318-024-00342-8

By:

Kurniyati, Kurni;
Clark, Nicholas D;
Wang, Hongxia;
Deng, Yijie;
Sze, Ching Wooen;
Visser, Michelle B;
Malkowski, Michael G;
Li, Chunhao

Publication type:

Article

Developmental beta-cell death orchestrates the islet's inflammatory milieu by regulating immune system crosstalk.

Published in:

EMBO Journal, 2025, v. 44, n. 4, p. 1131, doi. 10.1038/s44318-024-00332-w

By:

Akhtar, Mohammad Nadeem;
Hnatiuk, Alisa;
Delgadillo-Silva, Luis;
Geravandi, Shirin;
Sameith, Katrin;
Reinhardt, Susanne;
Bernhardt, Katja;
Singh, Sumeet Pal;
Maedler, Kathrin;
Brusch, Lutz;
Ninov, Nikolay

Publication type:

Article

Structural insights into binding-site access and ligand recognition by human ABCB1.

Published in:

EMBO Journal, 2025, v. 44, n. 4, p. 991, doi. 10.1038/s44318-025-00361-z

By:

Kurre, Devanshu;
Dang, Phuoc X;
Le, Le T M;
Gadkari, Varun V;
Alam, Amer

Publication type:

Article

NADH-bound AIF activates the mitochondrial CHCHD4/MIA40 chaperone by a substrate-mimicry mechanism.

Published in:

EMBO Journal, 2025, v. 44, n. 4, p. 1220, doi. 10.1038/s44318-024-00360-6

By:

Brosey, Chris A;
Shen, Runze;
Tainer, John A

Publication type:

Article

Two FAM134B isoforms differentially regulate ER dynamics during myogenesis.

Published in:

EMBO Journal, 2025, v. 44, n. 4, p. 1039, doi. 10.1038/s44318-024-00356-2

By:

Buonomo, Viviana;
Lohachova, Kateryna;
Reggio, Alessio;
Cano-Franco, Sara;
Cillo, Michele;
Santorelli, Lucia;
Venditti, Rossella;
Polishchuk, Elena;
Peluso, Ivana;
Brunello, Lorene;
Cirillo, Carmine;
Petrosino, Sara;
Silva, Malan;
De Cegli, Rossella;
Di Bartolomeo, Sabrina;
Gargioli, Cesare;
Swuec, Paolo;
Cortese, Mirko;
Stolz, Alexandra;
Bhaskara, Ramachandra M

Publication type:

Article

Specialized pericyte subtypes in the pulmonary capillaries.

Published in:

EMBO Journal, 2025, v. 44, n. 4, p. 1074, doi. 10.1038/s44318-024-00349-1

By:

Klouda, Timothy;
Kim, Yunhye;
Baek, Seung-Han;
Bhaumik, Mantu;
Li, Yan;
Liu, Yu;
Wu, Joseph C;
Raby, Benjamin A;
Perez, Vinicio de Jesus;
Yuan, Ke

Publication type:

Article

MTCH2 controls energy demand and expenditure to fuel anabolism during adipogenesis.

Published in:

EMBO Journal, 2025, v. 44, n. 4, p. 1007, doi. 10.1038/s44318-024-00335-7

By:

Chourasia, Sabita;
Petucci, Christopher;
Shoffler, Clarissa;
Abbasian, Dina;
Wang, Hu;
Han, Xianlin;
Sivan, Ehud;
Brandis, Alexander;
Mehlman, Tevie;
Malitsky, Sergey;
Itkin, Maxim;
Sharp, Ayala;
Rotkopf, Ron;
Dassa, Bareket;
Regev, Limor;
Zaltsman, Yehudit;
Gross, Atan

Publication type:

Article

The integrated stress response drives MET oncogene overexpression in cancers.

Published in:

EMBO Journal, 2025, v. 44, n. 4, p. 1107, doi. 10.1038/s44318-024-00338-4

By:

Cerqua, Marina;
Foiani, Marco;
Boccaccio, Carla;
Comoglio, Paolo M;
Altintas, Dogus M

Publication type:

Article

Structure of a step II catalytically activated spliceosome from Chlamydomonas reinhardtii.

Published in:

EMBO Journal, 2025, v. 44, n. 4, p. 975, doi. 10.1038/s44318-024-00274-3

By:

Lu, Yichen;
Liang, Ke;
Zhan, Xiechao

Publication type:

Article