Works matching IS 01926233 AND DT 1999 AND VI 27 AND IP 1

Results: 26

Preclinical Development of Agents for the Treatment of Osteoporosis.

Published in:

Toxicologic Pathology, 1999, v. 27, n. 1, p. 143, doi. 10.1177/019262339902700126

By:

Hartke, James R.

Publication type:

Article

Animal Models of Arthritis: Relevance to Human Disease.

Published in:

Toxicologic Pathology, 1999, v. 27, n. 1, p. 134, doi. 10.1177/019262339902700125

By:

Bendele, Alison;
Mccomb, Jennifer;
Gould, TY;
Mcabee, Tracy;
Sennello, Gina;
Chlipala, Elizabeth;
Guy, Michael

Publication type:

Article

The Role of IL-10 in Inflammatory Bowel Disease: "Of Mice and Men".

Published in:

Toxicologic Pathology, 1999, v. 27, n. 1, p. 123, doi. 10.1177/019262339902700124

By:

Leach, Michael W.;
Davidson, Natalie J.;
Fort, Madeline M.;
Powrie, Fiona;
Rennick, Donna M.

Publication type:

Article

Tumor Models: Assessing Toxicity in Efficacy Studies.

Published in:

Toxicologic Pathology, 1999, v. 27, n. 1, p. 121, doi. 10.1177/019262339902700123

By:

Arp, Lawrence H.

Publication type:

Article

Mechanisms of Disease and Injury: Utilization of Mutants, Monoclonals, and Molecular Methods.

Published in:

Toxicologic Pathology, 1999, v. 27, n. 1, p. 115, doi. 10.1177/019262339902700122

By:

Schuh, Joann C.L.;
Harrington, Kimberly A.

Publication type:

Article

Utilization of Genetically Altered Animals in the Pharmaceutical Industry.

Published in:

Toxicologic Pathology, 1999, v. 27, n. 1, p. 111, doi. 10.1177/019262339902700121

By:

Rudmann, Daniel G.;
Durham, Stephen K.

Publication type:

Article

Revolution through Genomics in Investigative and Discovery Toxicology.

Published in:

Toxicologic Pathology, 1999, v. 27, n. 1, p. 107, doi. 10.1177/019262339902700120

By:

Rodi, Charles P.;
Bunch, Roderick T.;
Curtiss, Sandra W.;
Kier, Larry D.;
Cabonce, Marc A.;
Davila, Julio C.;
Mitchell, Michael D.;
Alden, Carl L.;
Morris, Dale L.

Publication type:

Article

The Pathologist and Toxicologist in Pharmaceutical Product Discovery.

Published in:

Toxicologic Pathology, 1999, v. 27, n. 1, p. 104, doi. 10.1177/019262339902700119

By:

Alden, Carl L.;
Sagartz, John E.;
Smith, Peter F.;
Wilson, Alan G.;
Bunch, Roderick T.;
Morris, Dale L.

Publication type:

Article

Safety Evaluation of Human Living Skin Equivalents.

Published in:

Toxicologic Pathology, 1999, v. 27, n. 1, p. 101, doi. 10.1177/019262339902700118

By:

Nemecek, Georgina M.;
Dayan, Anthony D.

Publication type:

Article

Correlation of Toxicity and Pharmacokinetic Properties of a Phosphorothioate Oligonucleotide Designed to Inhibit ICAM-1.

Published in:

Toxicologic Pathology, 1999, v. 27, n. 1, p. 95, doi. 10.1177/019262339902700117

By:

Henry, Scott P.;
Templin, Michael V.;
Gillett, Nancy;
Rojko, Jennifer;
Levin, Arthur A.

Publication type:

Article

BR96 sFv-PE40 Immunotoxin: Nonclinical Safety Assessment.

Published in:

Toxicologic Pathology, 1999, v. 27, n. 1, p. 87, doi. 10.1177/019262339902700116

By:

Haggerty, H.G.;
Warner, W.A.;
Comereski, C.R.;
Peden, W.M.;
Mezza, L.E.;
Damle, B.D.;
Siegall, C.B.;
Davidson, T.J.

Publication type:

Article

Preclinical Safety Evaluation of rhuMAbVEGF, an Antiangiogenic Humanized Monoclonal Antibody.

Published in:

Toxicologic Pathology, 1999, v. 27, n. 1, p. 78, doi. 10.1177/019262339902700115

By:

Ryan, Anne M.;
Eppler, Dorothy Bates;
Hagler, Kelly E.;
Bruner, Richard H.;
Thomford, Peter J.;
Hall, Robert L.;
Shopp, George M.;
O'Neill, Charles A.

Publication type:

Article

Development of a Recombinant Growth Factor and Fusion Protein: Lessons from GM-CSF.

Published in:

Toxicologic Pathology, 1999, v. 27, n. 1, p. 72, doi. 10.1177/019262339902700114

By:

Schuh, Joann C.L.;
Morrissey, Philip J.

Publication type:

Article

Preclinical and Early Clinical Development of Keratinocyte Growth Factor, an Epithelial- Specific Tissue Growth Factor.

Published in:

Toxicologic Pathology, 1999, v. 27, n. 1, p. 64, doi. 10.1177/019262339902700113

By:

Danilenko, Dimitry M.

Publication type:

Article

The Toxicology of Interleukin-12: A Review.

Published in:

Toxicologic Pathology, 1999, v. 27, n. 1, p. 58, doi. 10.1177/019262339902700112

By:

Car, Bruce D.;
Eng, Vicki M.;
Lipman, Jack M.;
Anderson, Timothy D.

Publication type:

Article

Toxicologic Pathology of Cytokines, Cytokine Receptors, and Other Recombinant Human Proteins.

Published in:

Toxicologic Pathology, 1999, v. 27, n. 1, p. 53, doi. 10.1177/019262339902700111

By:

Puri, Raj K.

Publication type:

Article

Molecular Pathology in the Preclinical Development of Biopharmaceuticals.

Published in:

Toxicologic Pathology, 1999, v. 27, n. 1, p. 48, doi. 10.1177/019262339902700110

By:

Gillett, Nancy A.;
Chan, Curtis M.

Publication type:

Article

Use of In Vivo Confocal Microscopy to Understand the Pathology of Accidental Ocular Irritation.

Published in:

Toxicologic Pathology, 1999, v. 27, n. 1, p. 44, doi. 10.1177/019262339902700109

By:

Maurer, J.K.;
Jester, J.V.

Publication type:

Article

Flow Cytometry in the Preclinical Development of Biopharmaceuticals.

Published in:

Toxicologic Pathology, 1999, v. 27, n. 1, p. 32, doi. 10.1177/019262339902700107

By:

Gossett, Kent A.;
Narayanan, Padma K.;
Williams, Donna M.;
Gore, Elizabeth R.;
Herzyk, Danuta J.;
Hart, Timothy K.;
Sellers, Teresa S.

Publication type:

Article

Safety Assessment of Biotechnology-Derived Pharmaceuticals: ICH and Beyond.

Published in:

Toxicologic Pathology, 1999, v. 27, n. 1, p. 27, doi. 10.1177/019262339902700106

By:

Serabian, Mercedes A.;
Pilaro, Anne M.

Publication type:

Article

Regulatory Decision Strategy for Entry of a Novel Biologic Therapeutic with a Clinically Unmonitorable Toxicity into Clinical Trials: Pre-IND Meetings and a Case Example.

Published in:

Toxicologic Pathology, 1999, v. 27, n. 1, p. 22, doi. 10.1177/019262339902700105

By:

Black, Lauren E.;
Bendele, Alison M.;
Bendele, Ray A.;
Zack, Philip M.;
Hamilton, Marta

Publication type:

Article

Efficacy and Concentration-Response of Murine Anti-VEGF Monoclonal Antibody in Tumor-Bearing Mice and Extrapolation to Humans.

Published in:

Toxicologic Pathology, 1999, v. 27, n. 1, p. 14, doi. 10.1177/019262339902700104

By:

Mordenti, Joyce;
Thomsen, Karen;
Licko, Vojtech;
Chen, Helen;
Gloria Meng, Y.;
Ferrara, Napoleone

Publication type:

Article

Lesions and Identification of Crystalline Precipitates of Glycoprotein IIb-IIIa Antagonists in the Rat Kidney.

Published in:

Toxicologic Pathology, 1999, v. 27, n. 1, p. 38, doi. 10.1177/019262339902700108

By:

Levin, Stuart;
Friedman, Robert M.;
Cortez, Enriqueta;
Hribar, Jeremy;
Nicholas, Mark;
Schlessinger, Sally;
Fouant, Monique;
Khan, Nasir

Publication type:

Article

Synthetic Oligonucleotides: The Development of Antisense Therapeutics.

Published in:

Toxicologic Pathology, 1999, v. 27, n. 1, p. 8, doi. 10.1177/019262339902700103

By:

Monteith, David K.;
Levin, Arthur A.

Publication type:

Article

Pharmacology and Safety Assessment of Humanized Monoclonal Antibodies for Therapeutic Use.

Published in:

Toxicologic Pathology, 1999, v. 27, n. 1, p. 1, doi. 10.1177/019262339902700101

By:

Klingbeil, Corine;
Hsu, Di-Hwei

Publication type:

Article

Preclinical Development Strategies for Novel Gene Therapeutic Products.

Published in:

Toxicologic Pathology, 1999, v. 27, n. 1, p. 4, doi. 10.1177/019262339902700102

By:

Pilaro, Anne M.;
Serabian, Mercedes A.

Publication type:

Article