Works matching IS 01676997 AND DT 2018 AND VI 36 AND IP 3

Results: 20

Exacerbation of autoimmune hemolytic anemia induced by the first dose of programmed death-1 inhibitor pembrolizumab: a case report.

Published in:

Investigational New Drugs, 2018, v. 36, n. 3, p. 509, doi. 10.1007/s10637-018-0561-5

By:

Ogawa, Kenta;
Ito, Jiro;
Fujimoto, Daichi;
Morita, Mari;
Yoshizumi, Yuko;
Ariyoshi, Koichi;
Tomii, Keisuke;
Katakami, Nobuyuki

Publication type:

Article

Phase II trial of ifosfamide in combination with the VEGFR inhibitor sorafenib in advanced soft tissue sarcoma: a Spanish group for research on sarcomas (GEIS) study.

Published in:

Investigational New Drugs, 2018, v. 36, n. 3, p. 468, doi. 10.1007/s10637-018-0583-z

By:

García del Muro, Xavier;
Maurel, Joan;
Martínez Trufero, Javier;
Lavernia, Javier;
López Pousa, Antonio;
de las Peñas, Ramón;
Cubedo, Ricardo;
Berros, José Pablo;
Casado Herráez, Antonio;
de Juan, Ana;
Martín Broto, Javier

Publication type:

Article

A call for improved transparency in financial aspects of clinical trials: a case study of the CREATE-X trial in the New England Journal of Medicine.

Published in:

Investigational New Drugs, 2018, v. 36, n. 3, p. 517, doi. 10.1007/s10637-018-0577-x

By:

Ozaki, Akihiko;
Takita, Morihito;
Tanimoto, Tetsuya

Publication type:

Article

Pazopanib-related tumor lysis syndrome in metastatic clear cell renal cell carcinoma: a case report.

Published in:

Investigational New Drugs, 2018, v. 36, n. 3, p. 513, doi. 10.1007/s10637-018-0576-y

By:

van Kalleveen, Michael W.;
Walraven, Maudy;
Hendriks, Mathijs P.

Publication type:

Article

A phase 2 study of OSI-906 (linsitinib, an insulin-like growth factor receptor-1 inhibitor) in patients with asymptomatic or mildly symptomatic (non-opioid requiring) metastatic castrate resistant prostate cancer (CRPC).

Published in:

Investigational New Drugs, 2018, v. 36, n. 3, p. 451, doi. 10.1007/s10637-018-0574-0

By:

Barata, Pedro;
Cooney, Matthew;
Tyler, Allison;
Wright, John;
Dreicer, Robert;
Garcia, Jorge A.

Publication type:

Article

Drug approval based on randomized phase 3 trials for relapsed malignancy: analysis of oncologic drugs granted accelerated approval, publications and clinical trial databases.

Published in:

Investigational New Drugs, 2018, v. 36, n. 3, p. 487, doi. 10.1007/s10637-018-0572-2

By:

Nagai, Sumimasa;
Ozawa, Keiya

Publication type:

Article

A phase II study of the dual mTOR inhibitor MLN0128 in patients with metastatic castration resistant prostate cancer.

Published in:

Investigational New Drugs, 2018, v. 36, n. 3, p. 458, doi. 10.1007/s10637-018-0578-9

By:

Graham, Laura;
Banda, Kalyan;
Torres, Alba;
Carver, Brett S.;
Chen, Yu;
Pisano, Katie;
Shelkey, Greg;
Curley, Tracy;
Scher, Howard I.;
Lotan, Tamara L.;
Hsieh, Andrew C.;
Rathkopf, Dana E.

Publication type:

Article

Everolimus induced mood changes in breast cancer patients: a case-control study.

Published in:

Investigational New Drugs, 2018, v. 36, n. 3, p. 503, doi. 10.1007/s10637-017-0554-9

By:

Mir, Olivier;
Salvador, Alexandre;
Dauchy, Sarah;
Ropert, Stanislas;
Lemogne, Cédric;
Gaillard, Raphaël

Publication type:

Article

Prognostic Implication of Inflammation-based Prognostic Scores in Patients with Intrahepatic Cholangiocarcinoma Treated with First-line Gemcitabine plus Cisplatin.

Published in:

Investigational New Drugs, 2018, v. 36, n. 3, p. 496, doi. 10.1007/s10637-017-0548-7

By:

Cho, Hyungwoo;
Yoo, Changhoon;
Kim, Kyu-pyo;
Jeong, Jae Ho;
Kang, Jihoon;
Chang, Heung-Moon;
Lee, Sang Soo;
Park, Do Hyun;
Song, Tae Jun;
Lee, Sung Koo;
Kim, Myung-Hwan;
Lee, Han Chu;
Lim, Young-Suk;
Kim, Kang Mo;
Shim, Ju Hyun;
Hwang, Shin;
Song, Gi-Won;
Moon, Deok-Bog;
Lee, Jae Hoon;
Lee, Young-Joo

Publication type:

Article

Hepatic safety analysis of trabectedin: results of a pharmacokinetic study with trabectedin in patients with hepatic impairment and experience from a phase 3 clinical trial.

Published in:

Investigational New Drugs, 2018, v. 36, n. 3, p. 476, doi. 10.1007/s10637-017-0546-9

By:

Calvo, Emiliano;
Azaro, Analia;
Rodon, Jordi;
Dirix, Luc;
Huizing, Manon;
Senecal, Francis Mark;
LoRusso, Patricia;
Yee, Lorrin;
Poggesi, Italo;
de Jong, Jan;
Triantos, Spyros;
Park, Youn C.;
Knoblauch, Roland E.;
Parekh, Trilok V.;
Demetri, George D.;
von Mehren, Margaret

Publication type:

Article

The sirtuin 1/2 inhibitor tenovin-1 induces a nonlinear apoptosis-inducing factor-dependent cell death in a p53 null Ewing’s sarcoma cell line.

Published in:

Investigational New Drugs, 2018, v. 36, n. 3, p. 396, doi. 10.1007/s10637-017-0541-1

By:

Marx, Christian;
Marx-Blümel, Lisa;
Lindig, Nora;
Thierbach, René;
Hoelzer, Doerte;
Becker, Sabine;
Wittig, Susan;
Lehmann, Roland;
Slevogt, Hortense;
Heinzel, Thorsten;
Wang, Zhao-Qi;
Beck, James F.;
Sonnemann, Jürgen

Publication type:

Article

Phase I study of the combination of quinacrine and erlotinib in patients with locally advanced or metastatic non small cell lung cancer.

Published in:

Investigational New Drugs, 2018, v. 36, n. 3, p. 435, doi. 10.1007/s10637-017-0515-3

By:

Bhateja, Priyanka;
Dowlati, Afshin;
Sharma, Neelesh

Publication type:

Article

ATP-binding cassette transporters limit the brain penetration of Wee1 inhibitors.

Published in:

Investigational New Drugs, 2018, v. 36, n. 3, p. 380, doi. 10.1007/s10637-017-0539-8

By:

de Gooijer, Mark C.;
Buil, Levi C. M.;
Beijnen, Jos H.;
van Tellingen, Olaf

Publication type:

Article

Cyclodextrin polymers as nanocarriers for sorafenib.

Published in:

Investigational New Drugs, 2018, v. 36, n. 3, p. 370, doi. 10.1007/s10637-017-0538-9

By:

Giglio, Valentina;
Viale, Maurizio;
Bertone, Vittorio;
Maric, Irena;
Vaccarone, Rita;
Vecchio, Graziella

Publication type:

Article

Contribution of reactive oxygen species to the anticancer activity of aminoalkanol derivatives of xanthone.

Published in:

Investigational New Drugs, 2018, v. 36, n. 3, p. 355, doi. 10.1007/s10637-017-0537-x

By:

Sypniewski, Daniel;
Szkaradek, Natalia;
Loch, Tomasz;
Waszkielewicz, Anna M.;
Gunia-Krzyżak, Agnieszka;
Matczyńska, Daria;
Sołtysik, Dagna;
Marona, Henryk;
Bednarek, Ilona

Publication type:

Article

Dual Src and EGFR inhibition in combination with gemcitabine in advanced pancreatic cancer: phase I results.

Published in:

Investigational New Drugs, 2018, v. 36, n. 3, p. 442, doi. 10.1007/s10637-017-0519-z

By:

Cardin, Dana B.;
Goff, Laura W.;
Chan, Emily;
Whisenant, Jennifer G.;
Dan Ayers, G.;
Takebe, Naoko;
Arlinghaus, Lori R.;
Yankeelov, Thomas E.;
Berlin, Jordan;
Merchant, Nipun

Publication type:

Article

LFM-A13, a potent inhibitor of polo-like kinase, inhibits breast carcinogenesis by suppressing proliferation activity and inducing apoptosis in breast tumors of mice.

Published in:

Investigational New Drugs, 2018, v. 36, n. 3, p. 388, doi. 10.1007/s10637-017-0540-2

By:

Sahin, Kazim;
Tuzcu, Mehmet;
Yabas, Mehmet;
Orhan, Cemal;
Sahin, Nurhan;
Ozercan, Ibrahim H.

Publication type:

Article

Safety, pharmacokinetic, and pharmacodynamics of erdafitinib, a pan-fibroblast growth factor receptor (FGFR) tyrosine kinase inhibitor, in patients with advanced or refractory solid tumors.

Published in:

Investigational New Drugs, 2018, v. 36, n. 3, p. 424, doi. 10.1007/s10637-017-0514-4

By:

Nishina, Tomohiro;
Takahashi, Shunji;
Iwasawa, Ryota;
Noguchi, Hidehisa;
Aoki, Masayuki;
Doi, Toshihiko

Publication type:

Article

Phase I study of the combination of crizotinib (as a MET inhibitor) and dasatinib (as a c-SRC inhibitor) in patients with advanced cancer.

Published in:

Investigational New Drugs, 2018, v. 36, n. 3, p. 416, doi. 10.1007/s10637-017-0513-5

By:

Kato, Shumei;
Jardim, Denis L.;
Johnson, Faye M.;
Subbiah, Vivek;
Piha-Paul, Sarina;
Tsimberidou, Apostolia M.;
Falchook, Gerald S.;
Karp, Daniel;
Zinner, Ralph;
Wheler, Jennifer;
Janku, Filip;
Fu, Siqing;
Lim, JoAnn;
Bean, Stacie;
Nguyen, Ly;
Urban, Susan;
Browne, Elsa;
Meric-Bernstam, Funda;
Hong, David S.

Publication type:

Article

A phase I study to assess the mass balance, excretion, and pharmacokinetics of [<sup>14</sup>C]-ixazomib, an oral proteasome inhibitor, in patients with advanced solid tumors.

Published in:

Investigational New Drugs, 2018, v. 36, n. 3, p. 407, doi. 10.1007/s10637-017-0509-1

By:

Gupta, Neeraj;
Zhang, Steven;
Pusalkar, Sandeepraj;
Plesescu, Mihaela;
Chowdhury, Swapan;
Hanley, Michael J.;
Wang, Bingxia;
Xia, Cindy;
Zhang, Xiaoquan;
Venkatakrishnan, Karthik;
Shepard, Dale R.

Publication type:

Article