Works matching IS 01676997 AND DT 2018 AND VI 36 AND IP 1

Results: 21

Acknowledgement of Reviewers 2017.

Published in:: Investigational New Drugs, 2018, v. 36, n. 1, p. 170, doi. 10.1007/s10637-018-0565-1
Publication type:: Article

Phase II study of doxorubicin and thalidomide in patients with refractory aggressive fibromatosis.

Published in:

Investigational New Drugs, 2018, v. 36, n. 1, p. 114, doi. 10.1007/s10637-017-0542-0

By:

Liu, Xin;
Wang, Huijie;
Wu, Xianghua;
Hong, Xiaonan;
Luo, Zhiguo

Publication type:

Article

A phase 2 study of ontuxizumab, a monoclonal antibody targeting endosialin, in metastatic melanoma.

Published in:

Investigational New Drugs, 2018, v. 36, n. 1, p. 103, doi. 10.1007/s10637-017-0530-4

By:

D’Angelo, Sandra P.;
Hamid, Omid A.;
Tarhini, Ahmad;
Schadendorf, Dirk;
Chmielowski, Bartosz;
Collichio, Frances A.;
Pavlick, Anna C.;
Lewis, Karl D.;
Weil, Susan C.;
Heyburn, John;
Schweizer, Charles;
O’Shannessy, Daniel J.;
Carvajal, Richard D.

Publication type:

Article

Ganoderic acid, lanostanoid triterpene: a key player in apoptosis.

Published in:

Investigational New Drugs, 2018, v. 36, n. 1, p. 136, doi. 10.1007/s10637-017-0526-0

By:

Gill, Balraj Singh;
Navgeet;
Mehra, Richa;
Kumar, Vicky;
Kumar, Sanjeev

Publication type:

Article

Phase Ib/II study of gemcitabine, nab-paclitaxel, and pembrolizumab in metastatic pancreatic adenocarcinoma.

Published in:

Investigational New Drugs, 2018, v. 36, n. 1, p. 96, doi. 10.1007/s10637-017-0525-1

By:

Weiss, Glen J.;
Blaydorn, Lisa;
Beck, Julia;
Bornemann-Kolatzki, Kirsten;
Urnovitz, Howard;
Schütz, Ekkhard;
Khemka, Vivek

Publication type:

Article

Clinical toxicity of antibody drug conjugates: a meta-analysis of payloads.

Published in:

Investigational New Drugs, 2018, v. 36, n. 1, p. 121, doi. 10.1007/s10637-017-0520-6

By:

Masters, Joanna C.;
Nickens, Dana J.;
Xuan, Dawei;
Shazer, Ronald L.;
Amantea, Michael

Publication type:

Article

The kinesin Eg5 inhibitor K858 induces apoptosis and reverses the malignant invasive phenotype in human glioblastoma cells.

Published in:

Investigational New Drugs, 2018, v. 36, n. 1, p. 28, doi. 10.1007/s10637-017-0517-1

By:

Taglieri, Ludovica;
Rubinacci, Giovanna;
Giuffrida, Anna;
Carradori, Simone;
Scarpa, Susanna

Publication type:

Article

Crucial microRNAs and genes in metformin’s anti-pancreatic cancer effect explored by microRNA-mRNA integrated analysis.

Published in:

Investigational New Drugs, 2018, v. 36, n. 1, p. 20, doi. 10.1007/s10637-017-0508-2

By:

Li, Yilong;
Li, Le;
Zhang, Guangquan;
Wang, Yongwei;
Chen, Hua;
Kong, Rui;
Pan, Shangha;
Sun, Bei

Publication type:

Article

CUDC-907, a dual HDAC and PI3K inhibitor, reverses platinum drug resistance.

Published in:

Investigational New Drugs, 2018, v. 36, n. 1, p. 10, doi. 10.1007/s10637-017-0501-9

By:

To, Kenneth K. W.;
Fu, Li-wu

Publication type:

Article

AN-7, a butyric acid prodrug, sensitizes cutaneous T-cell lymphoma cell lines to doxorubicin via inhibition of DNA double strand breaks repair.

Published in:

Investigational New Drugs, 2018, v. 36, n. 1, p. 1, doi. 10.1007/s10637-017-0500-x

By:

Moyal, Lilach;
Goldfeiz, Neta;
Gorovitz, Batia;
Rephaeli, Ada;
Tal, Efrat;
Tarasenko, Nataly;
Nudelman, Abraham;
Ziv, Yael;
Hodak, Emmilia

Publication type:

Article

Germline <italic>BRCA</italic> mutations in Asian patients with pancreatic adenocarcinoma: a prospective study evaluating risk category for genetic testing.

Published in:

Investigational New Drugs, 2018, v. 36, n. 1, p. 163, doi. 10.1007/s10637-017-0497-1

By:

Lee, Kyoungmin;
Yoo, Changhoon;
Kim, Kyu-pyo;
Park, Kyoung-Jin;
Chang, Heung-Moon;
Kim, Tae Won;
Lee, Jae-Lyun;
Lee, Woochang;
Lee, Sang Soo;
Park, Do Hyun;
Song, Tae Jun;
Seo, Dong Wan;
Lee, Sung Koo;
Kim, Myung-Hwan;
Shin, Sang Hyun;
Hwang, Dae Wook;
Song, Ki Byung;
Lee, Jae Hoon;
Kim, Song Cheol;
Ryoo, Baek-Yeol

Publication type:

Article

Addition of an antiangiogenic therapy, bevacizumab, to gemcitabine plus oxaliplatin improves survival in advanced biliary tract cancers.

Published in:

Investigational New Drugs, 2018, v. 36, n. 1, p. 156, doi. 10.1007/s10637-017-0492-6

By:

Bréchon, Marie;
Dior, Marie;
Dréanic, Johann;
Brieau, Bertrand;
Guillaumot, Marie-Anne;
Brezault, Catherine;
Mir, Olivier;
Goldwasser, François;
Coriat, Romain

Publication type:

Article

Phase I dose escalation study of NMS-1286937, an orally available Polo-Like Kinase 1 inhibitor, in patients with advanced or metastatic solid tumors.

Published in:

Investigational New Drugs, 2018, v. 36, n. 1, p. 85, doi. 10.1007/s10637-017-0491-7

By:

Weiss, Glen J.;
Jameson, Gayle;
Von Hoff, Daniel D.;
Valsasina, Barbara;
Davite, Cristina;
Di Giulio, Claudia;
Fiorentini, Francesco;
Alzani, Rachele;
Carpinelli, Patrizia;
Di Sanzo, Alessandro;
Galvani, Arturo;
Isacchi, Antonella;
Ramanathan, Ramesh K.

Publication type:

Article

A Phase I study to determine safety, pharmacokinetics, and pharmacodynamics of ANF-RHO™, a novel PEGylated granulocyte colony-stimulating factor, in healthy volunteers.

Published in:

Investigational New Drugs, 2018, v. 36, n. 1, p. 75, doi. 10.1007/s10637-017-0490-8

By:

Misra, Hemant;
Berryman, John;
Jubin, Ronald;
Abuchowski, Abraham

Publication type:

Article

Feasibility of olanzapine, multi acting receptor targeted antipsychotic agent, for the prevention of emesis caused by continuous cisplatin- or ifosfamide-based chemotherapy.

Published in:

Investigational New Drugs, 2018, v. 36, n. 1, p. 151, doi. 10.1007/s10637-017-0487-3

By:

Bun, Seiko;
Yonemori, Kan;
Akagi, Toru;
Noguchi, Emi;
Shimoi, Tatsunori;
Shimomura, Akihiko;
Yunokawa, Mayu;
Shimizu, Chikako;
Fujiwara, Yasuhiro;
Makino, Yoshinori;
Hayashi, Yoshikazu;
Tamura, Kenji

Publication type:

Article

Chemotherapy-induced cardiomyopathy caused by Pemetrexed.

Published in:

Investigational New Drugs, 2018, v. 36, n. 1, p. 147, doi. 10.1007/s10637-017-0485-5

By:

Oyakawa, Takuya;
Iida, Kei;
Kusuhara, Masatoshi;
Kenmotsu, Hirotsugu;
Sugino, Takashi

Publication type:

Article

A case of nivolumab-related cholangitis and literature review: how to look for the right tools for a correct diagnosis of this rare immune-related adverse event.

Published in:

Investigational New Drugs, 2018, v. 36, n. 1, p. 144, doi. 10.1007/s10637-017-0484-6

By:

Gelsomino, Francesco;
Vitale, Giovanni;
Ardizzoni, Andrea

Publication type:

Article

Outcomes and prognostic factors for relapsed or refractory lymphoma patients in phase I clinical trials.

Published in:

Investigational New Drugs, 2018, v. 36, n. 1, p. 62, doi. 10.1007/s10637-017-0480-x

By:

Michot, Jean-Marie;
Benajiba, Lina;
Faivre, Laura;
Baldini, Capucine;
Haddag, Lelia;
Bonnet, Clement;
Massard, Christophe;
Bigot, Frederic;
Bigenwald, Camille;
Verret, Benjamin;
Thomas, Zoé A. P.;
Varga, Andrea;
Gazzah, Anas;
Hollebecque, Antoine;
Ghez, David;
Lazarovici, Julien;
Balheda, Rastilav;
Jeanson, Aurore;
Postel-Vinay, Sophie;
Danu, Alina

Publication type:

Article

A phase Ib study of everolimus combined with metformin for patients with advanced cancer.

Published in:

Investigational New Drugs, 2018, v. 36, n. 1, p. 53, doi. 10.1007/s10637-017-0478-4

By:

Molenaar, Remco J.;
van de Venne, Tim;
Weterman, Mariëtte J.;
Mathot, Ron A.;
Klümpen, Heinz-Josef;
Richel, Dick J.;
Wilmink, Johanna W.

Publication type:

Article

Phase I study of Nedaplatin, a platinum based antineoplastic drug, combined with nab-paclitaxel in patients with advanced squamous non–small cell lung cancer.

Published in:

Investigational New Drugs, 2018, v. 36, n. 1, p. 45, doi. 10.1007/s10637-017-0472-x

By:

Igawa, Satoshi;
Otani, Sakiko;
Nakahara, Yoshiro;
Ryuge, Shinichiro;
Hiyoshi, Yasuhiro;
Fukui, Tomoya;
Mitsufuji, Hisashi;
Kubota, Masaru;
Katagiri, Masato;
Sato, Yuichi;
Sasaki, Jiichiro;
Masuda, Noriyuki

Publication type:

Article

A phase I dose-escalation study of the safety and pharmacokinetics of a tablet formulation of voxtalisib, a phosphoinositide 3-kinase inhibitor, in patients with solid tumors.

Published in:

Investigational New Drugs, 2018, v. 36, n. 1, p. 36, doi. 10.1007/s10637-017-0467-7

By:

Mehnert, Janice M.;
Edelman, Gerald;
Stein, Mark;
Camisa, Heather;
Lager, Joanne;
Dedieu, Jean-François;
Ghuysen, Anne-Frédérique;
Sharma, Jyoti;
Liu, Li;
LoRusso, Patricia M.

Publication type:

Article