Works matching IS 01676997 AND DT 2017 AND VI 35 AND IP 4

Results: 16

Safety, tolerability and pharmacokinetics of the fibroblast growth factor receptor inhibitor AZD4547 in Japanese patients with advanced solid tumours: a Phase I study.

Published in:

Investigational New Drugs, 2017, v. 35, n. 4, p. 451, doi. 10.1007/s10637-016-0416-x

By:

Saka, Hideo;
Kitagawa, Chiyoe;
Kogure, Yoshihito;
Takahashi, Yasuo;
Fujikawa, Koshi;
Sagawa, Tamotsu;
Iwasa, Satoru;
Takahashi, Naoki;
Fukao, Taro;
Tchinou, Catherine;
Landers, Dónal;
Yamada, Yasuhide

Publication type:

Article

A phase I and pharmacokinetic study of afilbercept with FOLFIRI: comparison of Chinese and Caucasian populations.

Published in:

Investigational New Drugs, 2017, v. 35, n. 4, p. 463, doi. 10.1007/s10637-016-0421-0

By:

Xu, Jianming;
Li, Yingxin;
Sun, Xing;
Zhang, Dongsheng;
Liu, Rongrui;
Ziti-Ljajic, Samira;
Shi, Dongmei;
Xue, Fengying;
Le bail, Nathalie;
Xu, Ruihua

Publication type:

Article

Phase I study of lurbinectedin, a synthetic tetrahydroisoquinoline that inhibits activated transcription, induces DNA single- and double-strand breaks, on a weekly × 2 every-3-week schedule.

Published in:

Investigational New Drugs, 2017, v. 35, n. 4, p. 471, doi. 10.1007/s10637-017-0427-2

By:

Jimeno, Antonio;
Sharma, Manish;
Szyldergemajn, Sergio;
Gore, Lia;
Geary, David;
Diamond, Jennifer;
Fernandez Teruel, Carlos;
Soto Matos-Pita, Arturo;
Iglesias, Jorge;
Cullell-Young, Martin;
Ratain, Mark

Publication type:

Article

Metabolism and disposition of the anticancer quinolone derivative vosaroxin, a novel inhibitor of topoisomerase II.

Published in:

Investigational New Drugs, 2017, v. 35, n. 4, p. 478, doi. 10.1007/s10637-017-0428-1

By:

Nijenhuis, C.M.;
Lucas, L.;
Rosing, H.;
Huitema, A.D.R.;
Mergui-Roelvink, M.;
Jamieson, G.;
Fox, J.A.;
Mould, D.R.;
Schellens, J.H.M.;
Beijnen, J.H.

Publication type:

Article

Association of an aurora kinase a ( AURKA) gene polymorphism with progression-free survival in patients with advanced urothelial carcinoma treated with the selective aurora kinase a inhibitor alisertib.

Published in:

Investigational New Drugs, 2017, v. 35, n. 4, p. 524, doi. 10.1007/s10637-017-0440-5

By:

Necchi, Andrea;
Pintarelli, Giulia;
Raggi, Daniele;
Giannatempo, Patrizia;
Colombo, Francesca

Publication type:

Article

Diclofenac sex-divergent drug-drug interaction with Sunitinib: pharmacokinetics and tissue distribution in male and female mice.

Published in:

Investigational New Drugs, 2017, v. 35, n. 4, p. 399, doi. 10.1007/s10637-017-0447-y

By:

Chew, Chii;
Ng, Salby;
Chee, Yun;
Koo, Teng;
Liew, Ming;
Chee, Evelyn;
Modamio, Pilar;
Fernández, Cecilia;
Mariño, Eduardo;
Segarra, Ignacio

Publication type:

Article

Effects of histone deacetylase inhibitory prodrugs on epigenetic changes and DNA damage response in tumor and heart of glioblastoma xenograft.

Published in:

Investigational New Drugs, 2017, v. 35, n. 4, p. 412, doi. 10.1007/s10637-017-0448-x

By:

Tarasenko, Nataly;
Nudelman, Abraham;
Rozic, Gabriela;
Cutts, Suzanne;
Rephaeli, Ada

Publication type:

Article

Lung cancer and β-glucans: review of potential therapeutic applications.

Published in:

Investigational New Drugs, 2017, v. 35, n. 4, p. 509, doi. 10.1007/s10637-017-0449-9

By:

Roudi, Raheleh;
Mohammadi, Shahla;
Roudbary, Maryam;
Mohsenzadegan, Monireh

Publication type:

Article

Erratum to: Sarcopenic overweight is associated with early acute limiting toxicity of anti-PD1 checkpoint inhibitors in melanoma patients.

Published in:

2017

By:

Heidelberger, Valentine;
Goldwasser, François;
Kramkimel, Nora;
Jouinot, Anne;
Huillard, Olivier;
Boudou-Rouquette, Pascaline;
Chanal, Johan;
Arrondeau, Jennifer;
Franck, Nathalie;
Alexandre, Jérôme;
Blanchet, Benoît;
Leroy, Karen;
Avril, Marie-Françoise;
Dupin, Nicolas;
Aractingi, Sélim

Publication type:

Erratum

Risk of hypertension with ramucirumab-based therapy in solid tumors: data from a literature based meta-analysis.

Published in:

Investigational New Drugs, 2017, v. 35, n. 4, p. 518, doi. 10.1007/s10637-017-0452-1

By:

Roviello, Giandomenico;
Pacifico, Chiara;
Corona, Paola;
Generali, Daniele

Publication type:

Article

MPT0B002, a novel microtubule inhibitor, downregulates T315I mutant Bcr-Abl and induces apoptosis of imatinib-resistant chronic myeloid leukemia cells.

Published in:

Investigational New Drugs, 2017, v. 35, n. 4, p. 427, doi. 10.1007/s10637-017-0457-9

By:

Yeh, Yi-Yen;
Liou, Jing-Ping;
Lee, Yueh-Lun;
Lin, John;
Huang, Huei-Mei

Publication type:

Article

Phase II study of the Multikinase inhibitor of angiogenesis, Linifanib, in patients with metastatic and refractory colorectal cancer expressing mutated KRAS.

Published in:

Investigational New Drugs, 2017, v. 35, n. 4, p. 491, doi. 10.1007/s10637-017-0458-8

By:

Chan, Emily;
Goff, Laura;
Cardin, Dana;
Ancell, Kristin;
Smith, Stephen;
Whisenant, Jennifer;
Ye, Fei;
Berlin, Jordan

Publication type:

Article

Sarcopenic overweight is associated with early acute limiting toxicity of anti-PD1 checkpoint inhibitors in melanoma patients.

Published in:

Investigational New Drugs, 2017, v. 35, n. 4, p. 436, doi. 10.1007/s10637-017-0464-x

By:

Heidelberger, Valentine;
Goldwasser, François;
Kramkimel, Nora;
Jouinot, Anne;
Huillard, Olivier;
Boudou-Rouquette, Pascaline;
Chanal, Johan;
Arrondeau, Jennifer;
Franck, Nathalie;
Alexandre, Jérôme;
Blanchet, Benoît;
Leroy, Karen;
Avril, Marie-Françoise;
Dupin, Nicolas;
Aractingi, Sélim

Publication type:

Article

Imaging and clinicopathological features of nivolumab-related cholangitis in patients with non-small cell lung cancer.

Published in:

Investigational New Drugs, 2017, v. 35, n. 4, p. 529, doi. 10.1007/s10637-017-0453-0

By:

Kawakami, Hisato;
Tanizaki, Junko;
Tanaka, Kaoru;
Haratani, Koji;
Hayashi, Hidetoshi;
Takeda, Masayuki;
Kamata, Ken;
Takenaka, Mamoru;
Kimura, Masatomo;
Chikugo, Takaaki;
Sato, Takao;
Kudo, Masatoshi;
Ito, Akihiko;
Nakagawa, Kazuhiko

Publication type:

Article

Phase 1 study of narnatumab, an anti-RON receptor monoclonal antibody, in patients with advanced solid tumors.

Published in:

Investigational New Drugs, 2017, v. 35, n. 4, p. 442, doi. 10.1007/s10637-016-0413-0

By:

LoRusso, Patricia;
Gounder, Mrinal;
Jalal, Shadia;
André, Valérie;
Kambhampati, Siva;
Loizos, Nick;
Hall, Jennifer;
Holzer, Timothy;
Nasir, Aejaz;
Cosaert, Jan;
Kauh, John;
Chiorean, E.

Publication type:

Article

Phase II study of lanreotide autogel in Japanese patients with unresectable or metastatic well-differentiated neuroendocrine tumors.

Published in:

Investigational New Drugs, 2017, v. 35, n. 4, p. 499, doi. 10.1007/s10637-017-0466-8

By:

Ito, Tetsuhide;
Honma, Yoshitaka;
Hijioka, Susumu;
Kudo, Atsushi;
Fukutomi, Akira;
Nozaki, Akira;
Kimura, Yasutoshi;
Motoi, Fuyuhiko;
Isayama, Hiroyuki;
Komoto, Izumi;
Hisamatsu, Seiichi;
Nakajima, Akihiro;
Shimatsu, Akira

Publication type:

Article