Works matching IS 01676997 AND DT 2017 AND VI 35 AND IP 1

Results: 15

Osimertinib-induced interstitial lung disease after treatment with anti-PD1 antibody.

Published in:

Investigational New Drugs, 2017, v. 35, n. 1, p. 105, doi. 10.1007/s10637-016-0389-9

By:

Mamesaya, Nobuaki;
Kenmotsu, Hirotsugu;
Katsumata, Mineo;
Nakajima, Takashi;
Endo, Masahiro;
Takahashi, Toshiaki

Publication type:

Article

A phase I dose-escalation study of TAK-733, an investigational oral MEK inhibitor, in patients with advanced solid tumors.

Published in:

Investigational New Drugs, 2017, v. 35, n. 1, p. 47, doi. 10.1007/s10637-016-0391-2

By:

Adjei, Alex;
LoRusso, Patricia;
Ribas, Antoni;
Sosman, Jeffrey;
Pavlick, Anna;
Dy, Grace;
Zhou, Xiaofei;
Gangolli, Esha;
Kneissl, Michelle;
Faucette, Stephanie;
Neuwirth, Rachel;
Bózon, Viviana

Publication type:

Article

Evaluating the role of phase I expansion cohorts in oncologic drug development.

Published in:

Investigational New Drugs, 2017, v. 35, n. 1, p. 108, doi. 10.1007/s10637-016-0394-z

By:

Norris, Robin;
Behtaj, Mohadese;
Fu, Pingfu;
Dowlati, Afshin

Publication type:

Article

Incidence of infusion reactions to anti-neoplastic agents in early phase clinical trials: The MD Anderson Cancer Center experience.

Published in:

Investigational New Drugs, 2017, v. 35, n. 1, p. 59, doi. 10.1007/s10637-016-0395-y

By:

Bupathi, Manojkumar;
Hajjar, Joud;
Bean, Stacie;
Fu, Siqing;
Hong, David;
Karp, Daniel;
Stephen, Bettzy;
Hess, Kenneth;
Meric-Bernstam, Funda;
Naing, Aung

Publication type:

Article

A photodynamic bifunctional conjugate for prostate cancer: an in vitro mechanistic study.

Published in:

Investigational New Drugs, 2017, v. 35, n. 1, p. 115, doi. 10.1007/s10637-016-0396-x

By:

Rapozzi, Valentina;
Varchi, Greta;
Della Pietra, Emilia;
Ferroni, Claudia;
Xodo, Luigi

Publication type:

Article

4-methylumbelliferone and imatinib combination enhances senescence induction in chronic myeloid leukemia cell lines.

Published in:

Investigational New Drugs, 2017, v. 35, n. 1, p. 1, doi. 10.1007/s10637-016-0397-9

By:

Lompardía, Silvina;
Díaz, Mariángeles;
Papademetrio, Daniela;
Pibuel, Matías;
Álvarez, Élida;
Hajos, Silvia

Publication type:

Article

A phase I trial investigating pulsatile erlotinib in combination with gemcitabine and oxaliplatin in advanced biliary tract cancers.

Published in:

Investigational New Drugs, 2017, v. 35, n. 1, p. 95, doi. 10.1007/s10637-016-0406-z

By:

Goff, Laura;
Cardin, Dana;
Whisenant, Jennifer;
Du, Liping;
Koyama, Tatsuki;
Dahlman, Kimberly;
Salaria, Safia;
Young, Ruth;
Ciombor, Kristen;
Gilbert, Jill;
Smith, Stephen;
Chan, Emily;
Berlin, Jordan

Publication type:

Article

A phase 1 study combining the HER3 antibody seribantumab (MM-121) and cetuximab with and without irinotecan.

Published in:

Investigational New Drugs, 2017, v. 35, n. 1, p. 68, doi. 10.1007/s10637-016-0399-7

By:

Cleary, James;
McRee, Autumn;
Shapiro, Geoffrey;
Tolaney, Sara;
O'Neil, Bert;
Kearns, Jeffrey;
Mathews, Sara;
Nering, Rachel;
MacBeath, Gavin;
Czibere, Akos;
Sharma, Sunil;
Korn, W.

Publication type:

Article

The DNA methyltransferase inhibitor zebularine exerts antitumor effects and reveals BATF2 as a poor prognostic marker for childhood medulloblastoma.

Published in:

Investigational New Drugs, 2017, v. 35, n. 1, p. 26, doi. 10.1007/s10637-016-0401-4

By:

Andrade, Augusto;
Borges, Kleiton;
Suazo, Veridiana;
Geron, Lenisa;
Corrêa, Carolina;
Castro-Gamero, Angel;
Vasconcelos, Elton;
Oliveira, Ricardo;
Neder, Luciano;
Yunes, José;
Santos Aguiar, Simone;
Scrideli, Carlos;
Tone, Luiz

Publication type:

Article

Predictive factors of renal toxicities related to anti-VEGFR multikinase inhibitors in phase 1 trials.

Published in:

Investigational New Drugs, 2017, v. 35, n. 1, p. 79, doi. 10.1007/s10637-016-0402-3

By:

Boissier, Emilie;
Mir, Olivier;
Hollebecque, Antoine;
Izzedine, Hassan;
Ederhy, Stéphane;
Gazzah, Anas;
Bahleda, Rastislav;
Massard, Christophe;
Macquin-Mavier, Isabelle;
Tournigand, Christophe;
Spano, Jean-Philippe;
Soria, Jean-Charles;
Rousseau, Benoît

Publication type:

Article

Phase 1b study of orteronel in postmenopausal women with hormone-receptor positive (HR+) metastatic breast cancer.

Published in:

Investigational New Drugs, 2017, v. 35, n. 1, p. 87, doi. 10.1007/s10637-016-0403-2

By:

Rampurwala, Murtuza;
Wisinski, Kari;
Burkard, Mark;
Ehsani, Sima;
O'Regan, Ruth;
Carmichael, Lakeesha;
Kim, KyungMann;
Kolesar, Jill;
Tevaarwerk, Amye

Publication type:

Article

Targeting the protein ubiquitination machinery in melanoma by the NEDD8-activating enzyme inhibitor pevonedistat (MLN4924).

Published in:

Investigational New Drugs, 2017, v. 35, n. 1, p. 11, doi. 10.1007/s10637-016-0398-8

By:

Wong, Kit;
Micel, Lindsey;
Selby, Heather;
Tan, Aik;
Pitts, Todd;
Bagby, Stacey;
Spreafico, Anna;
Klauck, Peter;
Blakemore, Stephen;
Smith, Peter;
McDonald, Alice;
Berger, Allison;
Tentler, John;
Eckhardt, S.

Publication type:

Article

Erratum to: The DNA methyltransferase inhibitor zebularine exerts antitumor effects and reveals BATF2 as a poor prognostic marker for childhood medulloblastoma.

Published in:

2017

By:

Andrade, Augusto;
Borges, Kleiton;
Suazo, Veridiana;
Geron, Lenisa;
Corrêa, Carolina;
Castro-Gamero, Angel;
Vasconcelos, Elton;
Oliveira, Ricardo;
Neder, Luciano;
Yunes, José;
Aguiar, Simone;
Scrideli, Carlos;
Tone, Luiz

Publication type:

Erratum

Acknowledgement of Reviewers 2016.

Published in:: Investigational New Drugs, 2017, v. 35, n. 1, p. 125, doi. 10.1007/s10637-017-0426-3
Publication type:: Article

Phase Ia/Ib study of the pan-class I PI3K inhibitor pictilisib (GDC-0941) administered as a single agent in Japanese patients with solid tumors and in combination in Japanese patients with non-squamous non-small cell lung cancer.

Published in:

Investigational New Drugs, 2017, v. 35, n. 1, p. 37, doi. 10.1007/s10637-016-0382-3

By:

Yamamoto, Noboru;
Fujiwara, Yutaka;
Tamura, Kenji;
Kondo, Shunsuke;
Iwasa, Satoru;
Tanabe, Yuko;
Horiike, Atsushi;
Yanagitani, Noriko;
Kitazono, Satoru;
Inatani, Michiyasu;
Tanaka, Jun;
Nishio, Makoto

Publication type:

Article