Works matching IS 01676997 AND DT 2015 AND VI 33 AND IP 3

Results: 27

3,4′,5- trans-Trimethoxystilbene; a natural analogue of resveratrol with enhanced anticancer potency.

Published in:

2015

By:

Aldawsari, Fahad;
Velázquez-Martínez, Carlos

Publication type:

Journal Article

Posterior reversible encephalopathy syndrome induced by enzalutamide in a patient with castration-resistant prostate cancer.

Published in:

Investigational New Drugs, 2015, v. 33, n. 3, p. 751, doi. 10.1007/s10637-014-0193-3

By:

Crona, Daniel;
Whang, Young

Publication type:

Article

Does the Nerium oleander extract PBI-05204 have potential for pancreatic cancer therapy?

Published in:

2015

By:

Calderón-Montaño, José;
Burgos-Morón, Estefanía;
Guillén-Mancina, Emilio;
López-Lázaro, Miguel

Publication type:

Letter

Response to: Does the Nerium oleander extract PBI-05204 have potential for pancreatic cancer?

Published in:

2015

By:

Newman, Robert;
Yang, Peiying

Publication type:

Letter

Biomarker-driven phase 2 study of MK-2206 and selumetinib (AZD6244, ARRY-142886) in patients with colorectal cancer.

Published in:

Investigational New Drugs, 2015, v. 33, n. 3, p. 720, doi. 10.1007/s10637-015-0212-z

By:

Do, Khanh;
Speranza, Giovanna;
Bishop, Rachel;
Khin, Sonny;
Rubinstein, Larry;
Kinders, Robert;
Datiles, Manuel;
Eugeni, Michelle;
Lam, Michael;
Doyle, L.;
Doroshow, James;
Kummar, Shivaani

Publication type:

Article

Combretastatin A-4 derived imidazoles show cytotoxic, antivascular, and antimetastatic effects based on cytoskeletal reorganisation.

Published in:

Investigational New Drugs, 2015, v. 33, n. 3, p. 541, doi. 10.1007/s10637-015-0215-9

By:

Mahal, Katharina;
Biersack, Bernhard;
Caysa, Henrike;
Schobert, Rainer;
Mueller, Thomas

Publication type:

Article

The oncolytic virus, pelareorep, as a novel anticancer agent: a review.

Published in:

Investigational New Drugs, 2015, v. 33, n. 3, p. 761, doi. 10.1007/s10637-015-0216-8

By:

Chakrabarty, Romit;
Tran, Hue;
Selvaggi, Giovanni;
Hagerman, Allison;
Thompson, Brad;
Coffey, Matt

Publication type:

Article

Phase I and pharmacokinetic study of the novel anthracycline derivative 5-imino-13-deoxydoxorubicin (GPX-150) in patients with advanced solid tumors.

Published in:

Investigational New Drugs, 2015, v. 33, n. 3, p. 594, doi. 10.1007/s10637-015-0220-z

By:

Holstein, Sarah;
Bigelow, James;
Olson, Richard;
Vestal, Robert;
Walsh, Gerald;
Hohl, Raymond

Publication type:

Article

A phase I open-labeled, single-arm, dose-escalation, study of dichloroacetate (DCA) in patients with advanced solid tumors.

Published in:

Investigational New Drugs, 2015, v. 33, n. 3, p. 603, doi. 10.1007/s10637-015-0221-y

By:

Chu, Quincy;
Sangha, Randeep;
Spratlin, Jennifer;
Vos, Larissa;
Mackey, John;
McEwan, Alexander;
Venner, Peter;
Michelakis, Evangelos

Publication type:

Article

Phase 1 study of ixazomib, an investigational proteasome inhibitor, in advanced non-hematologic malignancies.

Published in:

Investigational New Drugs, 2015, v. 33, n. 3, p. 652, doi. 10.1007/s10637-015-0230-x

By:

Smith, David;
Kalebic, Thea;
Infante, Jeffrey;
Siu, Lillian;
Sullivan, Daniel;
Vlahovic, Gordana;
Kauh, John;
Gao, Feng;
Berger, Allison;
Tirrell, Stephen;
Gupta, Neeraj;
Bacco, Alessandra;
Berg, Deborah;
Liu, Guohui;
Lin, Jianchang;
Hui, Ai-Min;
Thompson, John

Publication type:

Article

3,4′,5- trans-Trimethoxystilbene; a natural analogue of resveratrol with enhanced anticancer potency.

Published in:

Investigational New Drugs, 2015, v. 33, n. 3, p. 775, doi. 10.1007/s10637-015-0222-x

By:

Aldawsari, Fahad;
Velázquez-Martínez, Carlos

Publication type:

Article

Xilonix, a novel true human antibody targeting the inflammatory cytokine interleukin-1 alpha, in non-small cell lung cancer.

Published in:

Investigational New Drugs, 2015, v. 33, n. 3, p. 621, doi. 10.1007/s10637-015-0226-6

By:

Hong, David;
Janku, Filip;
Naing, Aung;
Falchook, Gerald;
Piha-Paul, Sarina;
Wheler, Jennifer;
Fu, Siqing;
Tsimberidou, Apostolia;
Stecher, Michael;
Mohanty, Prasant;
Simard, John;
Kurzrock, Razelle

Publication type:

Article

Phase I study of the anti-MET antibody onartuzumab in patients with solid tumors and MET-positive lung cancer.

Published in:

Investigational New Drugs, 2015, v. 33, n. 3, p. 632, doi. 10.1007/s10637-015-0227-5

By:

Nishio, Makoto;
Horiike, Atsushi;
Nokihara, Hiroshi;
Horinouchi, Hidehito;
Nakamichi, Shinji;
Wakui, Hiroshi;
Ohyanagi, Fumiyoshi;
Kudo, Keita;
Yanagitani, Noriko;
Takahashi, Shunji;
Kuboki, Yasutoshi;
Yamamoto, Noboru;
Yamada, Yasuhide;
Abe, Masaichi;
Tahata, Takashi;
Tamura, Tomohide

Publication type:

Article

Convection-enhancement delivery of platinum-based drugs and Lipoplatin to optimize the concomitant effect with radiotherapy in F98 glioma rat model.

Published in:

Investigational New Drugs, 2015, v. 33, n. 3, p. 555, doi. 10.1007/s10637-015-0228-4

By:

Shi, Minghan;
Fortin, David;
Sanche, Léon;
Paquette, Benoit

Publication type:

Article

Phase I and pharmacokinetics/pharmacodynamics study of the MEK inhibitor RO4987655 in Japanese patients with advanced solid tumors.

Published in:

Investigational New Drugs, 2015, v. 33, n. 3, p. 641, doi. 10.1007/s10637-015-0229-3

By:

Nakamichi, Shinji;
Nokihara, Hiroshi;
Yamamoto, Noboru;
Yamada, Yasuhide;
Fujiwara, Yutaka;
Tamura, Yosuke;
Wakui, Hiroshi;
Honda, Kazunori;
Mizugaki, Hidenori;
Kitazono, Satoru;
Tanabe, Yuko;
Asahina, Hajime;
Yamazaki, Naoya;
Suzuki, Shigenobu;
Matsuoka, Mieko;
Ogita, Yoshitaka;
Tamura, Tomohide

Publication type:

Article

Phase I trial of volasertib, a Polo-like kinase inhibitor, plus platinum agents in solid tumors: safety, pharmacokinetics and activity.

Published in:

Investigational New Drugs, 2015, v. 33, n. 3, p. 611, doi. 10.1007/s10637-015-0223-9

By:

Awada, Ahmad;
Dumez, Herlinde;
Aftimos, Philippe;
Costermans, Jo;
Bartholomeus, Sylvie;
Forceville, Kathleen;
Berghmans, Thierry;
Meeus, Marie-Anne;
Cescutti, Jessica;
Munzert, Gerd;
Pilz, Korinna;
Liu, Dan;
Schöffski, Patrick

Publication type:

Article

Clinical outcomes in 66 patients with advanced gastric cancer treated in phase I trials: the NCCHE experience.

Published in:

Investigational New Drugs, 2015, v. 33, n. 3, p. 664, doi. 10.1007/s10637-015-0231-9

By:

Kawazoe, Akihito;
Shitara, Kohei;
Fukuoka, Shota;
Noguchi, Masaaki;
Kuboki, Yasutoshi;
Bando, Hideaki;
Okamoto, Wataru;
Kojima, Takashi;
Fuse, Nozomu;
Yoshino, Takayuki;
Ohtsu, Atsushi;
Doi, Toshihiko

Publication type:

Article

Inhibition of human vascular endothelial cell migration and capillary-like tube formation by the microtubule-stabilizing agent peloruside A.

Published in:

Investigational New Drugs, 2015, v. 33, n. 3, p. 564, doi. 10.1007/s10637-015-0232-8

By:

Chan, Ariane;
Singh, A.;
Northcote, Peter;
Miller, John

Publication type:

Article

The efficacy of amrubicin on central nervous system metastases originating from small-cell lung cancer: a case series of eight patients.

Published in:

Investigational New Drugs, 2015, v. 33, n. 3, p. 755, doi. 10.1007/s10637-015-0233-7

By:

Miura, Satoru;
Kaira, Kyoichi;
Kaira, Rieko;
Akamatsu, Hiroaki;
Ono, Akira;
Shukuya, Takehito;
Tsuya, Asuka;
Nakamura, Yukiko;
Kenmotsu, Hirotsugu;
Naito, Tateaki;
Murakami, Haruyasu;
Takahashi, Toshiaki;
Endo, Masahiro;
Yamamoto, Nobuyuki

Publication type:

Article

A phase 1 study of ABT-806 in subjects with advanced solid tumors.

Published in:

Investigational New Drugs, 2015, v. 33, n. 3, p. 671, doi. 10.1007/s10637-015-0234-6

By:

Cleary, James;
Reardon, David;
Azad, Nilofer;
Gandhi, Leena;
Shapiro, Geoffrey;
Chaves, Jorge;
Pedersen, Michelle;
Ansell, Peter;
Ames, William;
Xiong, Hao;
Munasinghe, Wijith;
Dudley, Matt;
Reilly, Edward;
Holen, Kyle;
Humerickhouse, Rod

Publication type:

Article

AZD3514, an oral selective androgen receptor down-regulator in patients with castration-resistant prostate cancer - results of two parallel first-in-human phase I studies.

Published in:

Investigational New Drugs, 2015, v. 33, n. 3, p. 679, doi. 10.1007/s10637-015-0235-5

By:

Omlin, A.;
Jones, R.;
Noll, R.;
Satoh, T.;
Niwakawa, M.;
Smith, S.;
Graham, J.;
Ong, M.;
Finkelman, R.;
Schellens, J.;
Zivi, A.;
Crespo, M.;
Riisnaes, R.;
Nava-Rodrigues, D.;
Malone, M.;
Dive, C.;
Sloane, R.;
Moore, D.;
Alumkal, J.;
Dymond, A.

Publication type:

Article

Pharmacokinetic drug-drug interaction study of the angiopoietin-1/angiopoietin-2-inhibiting peptibody trebananib (AMG 386) and paclitaxel in patients with advanced solid tumors.

Published in:

Investigational New Drugs, 2015, v. 33, n. 3, p. 691, doi. 10.1007/s10637-015-0236-4

By:

Diamond, Jennifer;
Wu, Benjamin;
Agarwal, Neeraj;
Bowles, Daniel;
Lam, Elaine;
Werner, Theresa;
Rasmussen, Erik;
Gamelin, Erick;
Soto, Felipe;
Friberg, Greg;
Sun, Yu-Nien;
Sharma, Sunil

Publication type:

Article

Sorafenib treatment in Child-Pugh A and B patients with advanced hepatocellular carcinoma: safety, efficacy and prognostic factors.

Published in:

Investigational New Drugs, 2015, v. 33, n. 3, p. 729, doi. 10.1007/s10637-015-0237-3

By:

Ogasawara, Sadahisa;
Chiba, Tetsuhiro;
Ooka, Yoshihiko;
Kanogawa, Naoya;
Saito, Tomoko;
Motoyama, Tenyu;
Suzuki, Eiichiro;
Tawada, Akinobu;
Kanai, Fumihiko;
Yokosuka, Osamu

Publication type:

Article

Phase I combination of pazopanib and everolimus in PIK3CA mutation positive/PTEN loss patients with advanced solid tumors refractory to standard therapy.

Published in:

Investigational New Drugs, 2015, v. 33, n. 3, p. 700, doi. 10.1007/s10637-015-0238-2

By:

Rodrigues, Heloisa;
Ke, Danxia;
Lim, JoAnn;
Stephen, Bettzy;
Bellido, Jorge;
Janku, Filip;
Zinner, Ralph;
Tsimberidou, Apostolia;
Hong, David;
Piha-Paul, Sarina;
Fu, Siqing;
Naing, Aung;
Subbiah, Vivek;
Karp, Daniel;
Falchook, Gerald;
Kurzrock, Razelle;
Wheler, Jennifer

Publication type:

Article

Screening and biological evaluation of myricetin as a multiple target inhibitor insulin, epidermal growth factor, and androgen receptor; in silico and in vitro.

Published in:

Investigational New Drugs, 2015, v. 33, n. 3, p. 575, doi. 10.1007/s10637-015-0240-8

By:

Singh, Pushpendra;
Bast, Felix

Publication type:

Article

Randomized phase III trial of regorafenib in metastatic colorectal cancer: analysis of the CORRECT Japanese and non-Japanese subpopulations.

Published in:

Investigational New Drugs, 2015, v. 33, n. 3, p. 740, doi. 10.1007/s10637-014-0154-x

By:

Yoshino, Takayuki;
Komatsu, Yoshito;
Yamada, Yasuhide;
Yamazaki, Kentaro;
Tsuji, Akihito;
Ura, Takashi;
Grothey, Axel;
Cutsem, Eric;
Wagner, Andrea;
Cihon, Frank;
Hamada, Yoko;
Ohtsu, Atsushi

Publication type:

Article

A first-in-human phase I trial of LY2780301, a dual p70 S6 kinase and Akt Inhibitor, in patients with advanced or metastatic cancer.

Published in:

Investigational New Drugs, 2015, v. 33, n. 3, p. 710, doi. 10.1007/s10637-015-0241-7

By:

Azaro, Analia;
Rodon, Jordi;
Calles, Antonio;
Braña, Irene;
Hidalgo, Manuel;
Lopez-Casas, Pedro;
Munoz, Manuel;
Westwood, Paul;
Miller, Joel;
Moser, Brian;
Ohnmacht, Ute;
Bumgardner, William;
Benhadji, Karim;
Calvo, Emiliano

Publication type:

Article