Works matching IS 01676997 AND DT 2013 AND VI 31 AND IP 6

Results: 31

Bio-distribution study of Reolysin® (pelareorep) through a single intravenous infusion in Sprague-Dawley rats.

Published in:

2013

By:

Chakrabarty, Romit;
Tran, Hue;
Boulay, Iohann;
Moran, Tanya;
Parenteau, Audrey;
Tavcar, Robert;
Bigras, Maude;
Hagerman, Allison;
Serl, Sarah;
Thompson, Brad;
Coffey, Matt

Publication type:

Journal Article

Addition of vandetanib to pegylated liposomal doxorubicin (PLD) in patients with recurrent ovarian cancer. A randomized phase I/II study of the AGO Study Group (AGO-OVAR 2.13)

Published in:

2013

By:

Harter, Philipp;
Sehouli, Jalid;
Kimmig, Rainer;
Rau, Jörn;
Hilpert, Felix;
Kurzeder, Christian;
Elser, Gabriele;
Bois, Andreas

Publication type:

Journal Article

Metabolism, mechanism of action and sensitivity profile of fluorocyclopentenylcytosine (RX-3117; TV-1360)

Published in:

2013

By:

Peters, Godefridus;
Smid, Kees;
Vecchi, Leonardo;
Kathmann, Ietje;
Sarkisjan, Dzjemma;
Honeywell, Richard;
Losekoot, Nienke;
Ohne, Osnat;
Orbach, Aric;
Blaugrund, Eran;
Jeong, Lak;
Lee, Young;
Ahn, Chang-Ho;
Kim, Deog

Publication type:

Journal Article

Sorafenib in patients with progressive malignant solitary fibrous tumors: a subgroup analysis from a phase II study of the French Sarcoma Group (GSF/GETO)

Published in:

2013

By:

Valentin, T.;
Fournier, C.;
Penel, N.;
Bompas, E.;
Chaigneau, L.;
Isambert, N.;
Chevreau, C.

Publication type:

Journal Article

A phase I study of vorinostat in combination with bortezomib in patients with advanced malignancies.

Published in:

Investigational New Drugs, 2013, v. 31, n. 6, p. 1539, doi. 10.1007/s10637-013-0029-6

By:

Schelman, William;
Traynor, Anne;
Holen, Kyle;
Kolesar, Jill;
Attia, Steven;
Hoang, Tien;
Eickhoff, Jens;
Jiang, Zhisheng;
Alberti, Dona;
Marnocha, Rebecca;
Reid, Joel;
Ames, Matthew;
McGovern, Renee;
Espinoza-Delgado, Igor;
Wright, John;
Wilding, George;
Bailey, Howard

Publication type:

Article

ZRX1, the first EGFR inhibitor-capecitabine based combi-molecule, requires carboxylesterase-mediated hydrolysis for optimal activity.

Published in:

Investigational New Drugs, 2013, v. 31, n. 6, p. 1409, doi. 10.1007/s10637-013-0008-y

By:

Ait-Tihyaty, Maria;
Rachid, Zakaria;
Larroque-Lombard, Anne-Laure;
Jean-Claude, Bertrand

Publication type:

Article

NCIC CTG IND.181: Phase I study of AT9283 given as a weekly 24 hour infusion in advanced malignancies.

Published in:

Investigational New Drugs, 2013, v. 31, n. 6, p. 1522, doi. 10.1007/s10637-013-0018-9

By:

Dent, S.;
Gelmon, K.;
Chi, K.;
Jonker, D.;
Wainman, N.;
Capier, C.;
Chen, E.;
Lyons, J.;
Seymour, L.

Publication type:

Article

Preclinical evaluation of the PI3K-mTOR dual inhibitor PF-04691502 as a novel therapeutic drug in nasopharyngeal carcinoma.

Published in:

Investigational New Drugs, 2013, v. 31, n. 6, p. 1399, doi. 10.1007/s10637-013-0007-z

By:

Wong, Chi;
Loong, Herbert;
Hui, Connie;
Lau, Cecilia;
Hui, Edwin;
Ma, Brigette;
Chan, Anthony

Publication type:

Article

A phase II study of cisplatin /S-1 in patients with carcinomas of unknown primary site.

Published in:

Investigational New Drugs, 2013, v. 31, n. 6, p. 1568, doi. 10.1007/s10637-013-0014-0

By:

Tsuya, Asuka;
Kurata, Takayasu;
Tamiya, Akihiro;
Okamoto, Isamu;
Ueda, Shinya;
Sakai, Daisuke;
Sugimoto, Naotoshi;
Matsumoto, Koji;
Goto, Isao;
Yamamoto, Nobuyuki;
Fukuoka, Masahiro;
Nakagawa, Kazuhiko

Publication type:

Article

Phase I study of sunitinib plus capecitabine/cisplatin or capecitabine/oxaliplatin in advanced gastric cancer.

Published in:

Investigational New Drugs, 2013, v. 31, n. 6, p. 1547, doi. 10.1007/s10637-013-0032-y

By:

Lee, K.-W.;
Park, S.;
Oh, D.-Y.;
Park, Y.-I.;
Khosravan, R.;
Lin, X.;
Lee, S.-Y.;
Roh, E.-J.;
Valota, O.;
Lechuga, M.;
Bang, Y.-J.

Publication type:

Article

Sunitinib combined with pemetrexed and carboplatin in patients with advanced solid malignancies-results of a phase I dose-escalation study.

Published in:

Investigational New Drugs, 2013, v. 31, n. 6, p. 1487, doi. 10.1007/s10637-013-0010-4

By:

Blais, Normand;
Camidge, D.;
Jonker, Derek;
Soulières, Denis;
Laurie, Scott;
Diab, Sami;
Ruiz-Garcia, Ana;
Thall, Aron;
Zhang, Ke;
Chao, Richard;
Chow, Laura

Publication type:

Article

Nanoparticulate paclitaxel demonstrates antitumor activity in PC3 and Ace-1 aggressive prostate cancer cell lines.

Published in:

Investigational New Drugs, 2013, v. 31, n. 6, p. 1609, doi. 10.1007/s10637-013-0006-0

By:

Axiak-Bechtel, Sandra;
Kumar, Senthil;
Dank, Kristin;
Clarkson, Nicole;
Selting, Kim;
Bryan, Jeffrey;
Rosol, Thomas;
Espinosa, Jahna;
Decedue, Charles

Publication type:

Article

UGT1A1 genotype-guided phase I study of irinotecan, oxaliplatin, and capecitabine.

Published in:

Investigational New Drugs, 2013, v. 31, n. 6, p. 1559, doi. 10.1007/s10637-013-0034-9

By:

Goetz, Matthew;
McKean, Heidi;
Reid, Joel;
Mandrekar, Sumithra;
Tan, Angelina;
Kuffel, Mary;
Safgren, Stephanie;
McGovern, Renee;
Goldberg, Richard;
Grothey, Axel;
McWilliams, Robert;
Erlichman, Charles;
Ames, Matthew

Publication type:

Article

A non-comparative phase II study of dose intensive chemotherapy with doxorubicin and ifosfamide followed by high dose ICE consolidation with PBSCT in non-resectable, high grade, adult type soft tissue sarcomas.

Published in:

Investigational New Drugs, 2013, v. 31, n. 6, p. 1592, doi. 10.1007/s10637-013-0027-8

By:

Hartmann, Jörg;
Horger, M.;
Kluba, T.;
Königsrainer, A.;
Zwart, P.;
Weyhern, C.;
Eckert, F.;
Budach, W.;
Bokemeyer, C.

Publication type:

Article

Phase I/II trial of pemetrexed plus nab-paclitaxel in advanced solid tumor patients with emphasis on non-small cell lung cancer.

Published in:

Investigational New Drugs, 2013, v. 31, n. 6, p. 1587, doi. 10.1007/s10637-013-0024-y

By:

Ho, Cheryl;
Davies, Angela;
Sangha, Randeep;
Lau, Derick;
Lara, Primo;
Chew, Helen;
Beckett, Laurel;
Mack, Philip;
Riess, Jonathan;
Gandara, David

Publication type:

Article

A phase I study of everolimus and CHOP in newly diagnosed peripheral T-cell lymphomas.

Published in:

Investigational New Drugs, 2013, v. 31, n. 6, p. 1514, doi. 10.1007/s10637-013-0015-z

By:

Kim, Seok;
Kang, Hye;
Kim, Jin;
Eom, Hyeon-Seok;
Huh, Jooryung;
Ko, Young;
Lee, Jongtae;
Yim, Dong-Seok;
Lee, Soo-Youn;
Park, Weon;
Yang, Woo;
Lee, Seung-Sook;
Suh, Cheolwon;
Kim, Won

Publication type:

Article

Addition of vandetanib to pegylated liposomal doxorubicin (PLD) in patients with recurrent ovarian cancer. A randomized phase I/II study of the AGO Study Group (AGO-OVAR 2.13).

Published in:

Investigational New Drugs, 2013, v. 31, n. 6, p. 1499, doi. 10.1007/s10637-013-0011-3

By:

Harter, Philipp;
Sehouli, Jalid;
Kimmig, Rainer;
Rau, Jörn;
Hilpert, Felix;
Kurzeder, Christian;
Elser, Gabriele;
Bois, Andreas

Publication type:

Article

Phase II trial of capecitabine and everolimus (RAD001) combination in refractory gastric cancer patients.

Published in:

Investigational New Drugs, 2013, v. 31, n. 6, p. 1580, doi. 10.1007/s10637-013-0022-0

By:

Lee, Su;
Lee, Jongtae;
Lee, Jeeyun;
Park, Se;
Park, Joon;
Park, Young;
Lim, Ho;
Kim, Kyoung-Mee;
Do, In-Gu;
Jung, Sin-Ho;
Yim, Dong-Seok;
Kang, Won

Publication type:

Article

Ketoprofen-loaded polymeric nanocapsules selectively inhibit cancer cell growth in vitro and in preclinical model of glioblastoma multiforme.

Published in:

Investigational New Drugs, 2013, v. 31, n. 6, p. 1424, doi. 10.1007/s10637-013-0016-y

By:

Silveira, Elita;
Chassot, Janaine;
Teixeira, Fernanda;
Azambuja, Juliana;
Debom, Gabriela;
Beira, Fátima;
Pino, Francisco;
Lourenço, Adriana;
Horn, Ana;
Cruz, Letícia;
Spanevello, Roselia;
Braganhol, Elizandra

Publication type:

Article

The diaryl oxazole PC-046 is a tubulin-binding agent with experimental anti-tumor efficacy in hematologic cancers.

Published in:

2013

By:

Landowski, Terry;
Samulitis, Betty;
Dorr, Robert

Publication type:

Report

Erratum to: Sunitinib malate in previously untreated, nonsquamous, non-small cell lung cancer patients over the age of 70 years: Results of a Phase II trial.

Published in:

2013

By:

Reynolds, Craig;
Spira, Alexander;
Gluck, Larry;
Bradie-Muller, Suzanne;
Zhan, Feng;
Boehm, Kristi;
Asmar, Lina

Publication type:

Correction Notice

A phase I, dose-escalation study of the Eg5-inhibitor EMD 534085 in patients with advanced solid tumors or lymphoma.

Published in:

Investigational New Drugs, 2013, v. 31, n. 6, p. 1530, doi. 10.1007/s10637-013-0026-9

By:

Hollebecque, A.;
Deutsch, E.;
Massard, C.;
Gomez-Roca, C.;
Bahleda, R.;
Ribrag, V.;
Bourgier, C.;
Lazar, V.;
Lacroix, L.;
Gazzah, A.;
Varga, A.;
Baere, T.;
Beier, F.;
Kroesser, S.;
Trang, K.;
Zenke, F.;
Klevesath, M.;
Soria, Jean-Charles

Publication type:

Article

Chemo-sensitisation of HeLa cells to Etoposide by a Benzoxazine in the absence of DNA-PK inhibition.

Published in:

Investigational New Drugs, 2013, v. 31, n. 6, p. 1466, doi. 10.1007/s10637-013-0031-z

By:

Fitzgibbon, Cheree;
Ihmaid, Saleh;
Al-Rawi, Jasim;
Meehan-Andrews, Terri;
Bradley, Christopher

Publication type:

Article

Metabolism, mechanism of action and sensitivity profile of fluorocyclopentenylcytosine (RX-3117; TV-1360).

Published in:

Investigational New Drugs, 2013, v. 31, n. 6, p. 1444, doi. 10.1007/s10637-013-0025-x

By:

Peters, Godefridus;
Smid, Kees;
Vecchi, Leonardo;
Kathmann, Ietje;
Sarkisjan, Dzjemma;
Honeywell, Richard;
Losekoot, Nienke;
Ohne, Osnat;
Orbach, Aric;
Blaugrund, Eran;
Jeong, Lak;
Lee, Young;
Ahn, Chang-Ho;
Kim, Deog

Publication type:

Article

Dual inhibition of MEK1/2 and EGFR synergistically induces caspase-3-dependent apoptosis in EGFR inhibitor-resistant lung cancer cells via BIM upregulation.

Published in:

Investigational New Drugs, 2013, v. 31, n. 6, p. 1458, doi. 10.1007/s10637-013-0030-0

By:

Song, Ji-Young;
Kim, Choung-Soo;
Lee, Je-Hwan;
Jang, Se;
Lee, Sang-wook;
Hwang, Jung;
Lim, Chulsoo;
Lee, Gilnam;
Seo, Jeongbeob;
Cho, Suk;
Choi, Jene

Publication type:

Article

Multicenter phase II study of everolimus in patients with metastatic or recurrent bone and soft-tissue sarcomas after failure of anthracycline and ifosfamide.

Published in:

Investigational New Drugs, 2013, v. 31, n. 6, p. 1602, doi. 10.1007/s10637-013-0028-7

By:

Yoo, Changhoon;
Lee, Jeeyun;
Rha, Sun;
Park, Kyong;
Kim, Tae;
Kim, Yu;
Lee, Hyo;
Lee, Kyung;
Ahn, Jin-Hee

Publication type:

Article

Bio-distribution study of Reolysin® (pelareorep) through a single intravenous infusion in Sprague-Dawley rats.

Published in:

Investigational New Drugs, 2013, v. 31, n. 6, p. 1476, doi. 10.1007/s10637-013-0033-x

By:

Chakrabarty, Romit;
Tran, Hue;
Boulay, Iohann;
Moran, Tanya;
Parenteau, Audrey;
Tavcar, Robert;
Bigras, Maude;
Hagerman, Allison;
Serl, Sarah;
Thompson, Brad;
Coffey, Matt

Publication type:

Article

OM-RCA-01, a novel humanized monoclonal antibody targeting fibroblast growth factor receptor 1, in renal cell carcinoma model.

Published in:

Investigational New Drugs, 2013, v. 31, n. 6, p. 1436, doi. 10.1007/s10637-013-0017-x

By:

Tsimafeyeu, Ilya;
Zaveleva, Elina;
Stepanova, Evgenia;
Low, Walter

Publication type:

Article

Multicenter phase II study of oxaliplatin and sorafenib in advanced gastric adenocarcinoma after failure of cisplatin and fluoropyrimidine treatment. A gemcad study.

Published in:

Investigational New Drugs, 2013, v. 31, n. 6, p. 1573, doi. 10.1007/s10637-013-0020-2

By:

Martin-Richard, M.;
Gallego, R.;
Pericay, C.;
Foncillas, J.;
Queralt, B.;
Casado, E.;
Barriuso, J.;
Iranzo, V.;
Juez, I.;
Visa, L.;
Saigi, E.;
Barnadas, A.;
Garcia-Albeniz, X.;
Maurel, J.

Publication type:

Article

Sorafenib in patients with progressive malignant solitary fibrous tumors: a subgroup analysis from a phase II study of the French Sarcoma Group (GSF/GETO).

Published in:

2013

By:

Valentin, T.;
Fournier, C.;
Penel, N.;
Bompas, E.;
Chaigneau, L.;
Isambert, N.;
Chevreau, C.

Publication type:

Report

Phase I clinical trial of lenalidomide in combination with temsirolimus in patients with advanced cancer.

Published in:

Investigational New Drugs, 2013, v. 31, n. 6, p. 1505, doi. 10.1007/s10637-013-0013-1

By:

Ganesan, Prasanth;
Piha-Paul, Sarina;
Naing, Aung;
Falchook, Gerald;
Wheler, Jennifer;
Janku, Filip;
Zinner, Ralph;
Laday, Shell;
Kies, Merrill;
Tsimberidou, Apostolia

Publication type:

Article