Works matching IS 01676997 AND DT 2010 AND VI 28

Results: 133

The DAC system and associations with multiple myeloma.

Published in:

Investigational New Drugs, 2010, v. 28, p. 28, doi. 10.1007/s10637-010-9589-x

By:

Ocio, Enrique;
San Miguel, Jesús

Publication type:

Article

Histone deacetylase inhibitors: potential targets responsible for their anti-cancer effect.

Published in:

Investigational New Drugs, 2010, v. 28, p. 3, doi. 10.1007/s10637-010-9596-y

By:

Dickinson, Michael;
Johnstone, Ricky;
Prince, H.

Publication type:

Article

The deacetylase inhibitors-here to stay!

Published in:

Investigational New Drugs, 2010, v. 28, p. 1, doi. 10.1007/s10637-010-9600-6

By:

Prince, H.

Publication type:

Article

Histone deacetylase inhibitors in Hodgkin lymphoma.

Published in:

Investigational New Drugs, 2010, v. 28, p. 21, doi. 10.1007/s10637-010-9588-y

By:

Buglio, Daniela;
Younes, Anas

Publication type:

Article

Deactylase inhibition in myeloproliferative neoplasms.

Published in:

Investigational New Drugs, 2010, v. 28, p. 50, doi. 10.1007/s10637-010-9590-4

By:

Mithraprabhu, Sridurga;
Grigoriadis, George;
Khong, Tiffany;
Spencer, Andrew

Publication type:

Article

Targeting histone deacetyalses in the treatment of B- and T-cell malignancies.

Published in:

Investigational New Drugs, 2010, v. 28, p. 58, doi. 10.1007/s10637-010-9591-3

By:

Zain, Jasmine;
O'Connor, Owen

Publication type:

Article

The DAC system and associations with acute leukemias and myelodysplastic syndromes.

Published in:

Investigational New Drugs, 2010, v. 28, p. 36, doi. 10.1007/s10637-010-9595-z

By:

Bug, Gesine;
Ottmann, Oliver

Publication type:

Article

New SRC/ABL inhibitors for chronic myeloid leukemia therapy show selectivity for T315I ABL mutant CD34(+) cells.

Published in:

2010

By:

Santucci, MA;
Mancini, M;
Corradi, V;
Lacobucci, I;
Martinelli, G;
Botta, M;
Schenone, S

Publication type:

Journal Article

DH9, a novel PPAR[gamma] agonist suppresses the proliferation of ADPKD epithelial cells: an association with an inhibition of [beta]-catenin signaling.

Published in:

2010

By:

Liu, Moyan;
Fu, Lili;
Liu, Chunyan;
Xiong, Xishan;
Gao, Xiang;
Xiao, Min;
Cai, Houan;
Hu, Huimin;
Wang, Xueqi;
Mei, Changlin

Publication type:

Journal Article

Synthesis, characterization and in vitro anti-tumor activities of novel 9-ethyl-9H-purine derivatives.

Published in:

2010

By:

Ningegowda, Raghu;
Grover, Amit;
Basappa;
Ranjith, S;
Rangappa, Kanchugarakoppal S;
Priya, BS;
Nanjunda Swamy, S

Publication type:

Journal Article

Antitumor activity of natural compounds, curcumin and PKF118-310, as Wnt/[beta]-catenin antagonists against human osteosarcoma cells.

Published in:

2010

By:

Leow, Pay-Chin;
Tian, Quan;
Ong, Zhan-Yuin;
Yang, Zheng;
Ee, Pui-Lai Rachel

Publication type:

Journal Article

Phase I study of non-pegylated liposomal doxorubicin in combination with ifosfamide in adult patients with metastatic soft tissue sarcomas.

Published in:

Investigational New Drugs, 2010, v. 28, n. 6, p. 834, doi. 10.1007/s10637-009-9288-7

By:

Stroppa, Elisa;
Bertuzzi, Alexia;
Comite, Gabriele;
Mussi, Chiara;
Lutman, Romano;
Barbato, Alfredo;
Santoro, Armando

Publication type:

Article

New SRC/ABL inhibitors for chronic myeloid leukemia therapy show selectivity for T315I ABL mutant CD34 cells.

Published in:

2010

By:

Santucci, Maria;
Mancini, Manuela;
Corradi, Valentina;
lacobucci, Ilaria;
Martinelli, Giovanni;
Botta, Maurizio;
Schenone, Silvia

Publication type:

Report

Reflex sympathetic dystrophy in patients with metastatic renal cell carcinoma treated with Everolimus.

Published in:

2010

By:

Massard, Christophe;
Fizazi, Karim;
Gross-Goupil, Marine;
Escudier, Bernard

Publication type:

Report

The epothilone B analogue ixabepilone in patients with advanced hepatobiliary cancers: a trial of the University of Chicago Phase II Consortium.

Published in:

Investigational New Drugs, 2010, v. 28, n. 6, p. 854, doi. 10.1007/s10637-009-9297-6

By:

Nimeiri, Halla;
Singh, Deepti;
Kasza, Kristen;
Taber, David;
Ansari, Rafat;
Vokes, Everett;
Kindler, Hedy

Publication type:

Article

MT7, a novel compound from a combinatorial library, arrests mitosis via inhibiting the polymerization of microtubules.

Published in:

Investigational New Drugs, 2010, v. 28, n. 6, p. 715, doi. 10.1007/s10637-009-9303-z

By:

Zhang, Zhixiang;
Meng, Tao;
He, Jingxue;
Li, Ming;
Tong, Lin-Jiang;
Xiong, Bing;
Lin, Liping;
Shen, Jingkang;
Miao, Ze-Hong;
Ding, Jian

Publication type:

Article

NBBS isolated from Pygeum africanum bark exhibits androgen antagonistic activity, inhibits AR nuclear translocation and prostate cancer cell growth.

Published in:

Investigational New Drugs, 2010, v. 28, n. 6, p. 729, doi. 10.1007/s10637-009-9304-y

By:

Papaioannou, Maria;
Schleich, Sonja;
Roell, Daniela;
Schubert, Undine;
Tanner, Tamzin;
Claessens, Frank;
Matusch, Rudolf;
Baniahmad, Aria

Publication type:

Article

Phase II study of gemcitabine and carboplatin in metastatic breast cancers with prior exposure to anthracyclines and taxanes.

Published in:

Investigational New Drugs, 2010, v. 28, n. 6, p. 859, doi. 10.1007/s10637-009-9305-x

By:

Chan, Daniel;
Yeo, Wee-Lee;
Tiemsim Cordero, Maricel;
Wong, Chiung-Ing;
Chuah, Benjamin;
Soo, Ross;
Tan, Sing-Huang;
Lim, Siew-Eng;
Goh, Boon-Cher;
Lee, Soo-Chin

Publication type:

Article

Phase I/II study of sunitinib malate in Japanese patients with gastrointestinal stromal tumor after failure of prior treatment with imatinib mesylate.

Published in:

Investigational New Drugs, 2010, v. 28, n. 6, p. 866, doi. 10.1007/s10637-009-9306-9

By:

Shirao, Kuniaki;
Nishida, Toshirou;
Doi, Toshihiko;
Komatsu, Yoshito;
Muro, Kei;
Li, Yinhua;
Ueda, Eiji;
Ohtsu, Atsushi

Publication type:

Article

Scaling the time-course of myelosuppression from rats to patients with a semi-physiological model.

Published in:

Investigational New Drugs, 2010, v. 28, n. 6, p. 744, doi. 10.1007/s10637-009-9308-7

By:

Friberg, Lena;
Sandström, Marie;
Karlsson, Mats

Publication type:

Article

Synthesis, characterization and in vitro anti-tumor activities of novel 9-ethyl-9 H-purine derivatives.

Published in:

Investigational New Drugs, 2010, v. 28, n. 6, p. 754, doi. 10.1007/s10637-009-9309-6

By:

Ningegowda, Raghu;
Grover, Amit;
Basappa;
Ranjith, S.;
Rangappa, Kanchugarakoppal;
Priya, B.;
Nanjunda Swamy, S.

Publication type:

Article

Antitumor activity of natural compounds, curcumin and PKF118-310, as Wnt/β-catenin antagonists against human osteosarcoma cells.

Published in:

Investigational New Drugs, 2010, v. 28, n. 6, p. 766, doi. 10.1007/s10637-009-9311-z

By:

Leow, Pay-Chin;
Tian, Quan;
Ong, Zhan-Yuin;
Yang, Zheng;
Ee, Pui-Lai

Publication type:

Article

Painful cervical esophageal erosion in a patient with advanced colorectal cancer treated with bevacizumab.

Published in:

2010

By:

Paiva, Carlos;
Maia, Yara;
Paiva, Bianca;
Lerco, Mauro

Publication type:

Report

DH9, a novel PPARγ agonist suppresses the proliferation of ADPKD epithelial cells: An association with an inhibition of β-catenin signaling.

Published in:

Investigational New Drugs, 2010, v. 28, n. 6, p. 783, doi. 10.1007/s10637-009-9313-x

By:

Liu, Moyan;
Fu, Lili;
Liu, Chunyan;
Xiong, Xishan;
Gao, Xiang;
Xiao, Min;
Cai, Houan;
Hu, Huimin;
Wang, Xueqi;
Mei, Changlin

Publication type:

Article

Dysphonia induced by vascular endothelium growth factor/vascular endothelium growth factor receptor inhibitors.

Published in:

2010

By:

Hartl, Dana;
Ferté, Charles;
Loriot, Yohann;
Gomez Roca, Carlos;
Bahleda, Rastislav;
Moldovan, Cristian;
Mir, Olivier;
Soria, Jean-Charles

Publication type:

Report

Justification of the starting dose as the main determinant of accrual time in dose-seeking oncology phase 1 trials.

Published in:

Investigational New Drugs, 2010, v. 28, n. 6, p. 839, doi. 10.1007/s10637-009-9317-6

By:

Penel, Nicolas;
Leblond, Pierre;
Lansiaux, Amélie;
Clisant, Stéphanie;
Dansin, Eric;
Adenis, Antoine;
Bonneterre, Jacques

Publication type:

Article

Lovastatin overcomes gefitinib resistance in human non-small cell lung cancer cells with K-Ras mutations.

Published in:

Investigational New Drugs, 2010, v. 28, n. 6, p. 791, doi. 10.1007/s10637-009-9319-4

By:

Park, In;
Kim, Jin;
Jung, Jae;
Han, Ji-Youn

Publication type:

Article

Phase I clinical and pharmacokinetic study of sorafenib in combination with carboplatin and paclitaxel in patients with advanced non-small cell lung cancer.

Published in:

Investigational New Drugs, 2010, v. 28, n. 6, p. 844, doi. 10.1007/s10637-009-9321-x

By:

Okamoto, Isamu;
Miyazaki, Masaki;
Morinaga, Ryotaro;
Kaneda, Hiroyasu;
Ueda, Shinya;
Hasegawa, Yoshikazu;
Satoh, Taroh;
Kawada, Akira;
Fukuoka, Masahiro;
Fukino, Koichi;
Tanigawa, Takahiko;
Nakagawa, Kazuhiko

Publication type:

Article

Antimetastatic activity of MONCPT in preclinical melanoma mice model.

Published in:

Investigational New Drugs, 2010, v. 28, n. 6, p. 800, doi. 10.1007/s10637-009-9323-8

By:

Yang, Xiao-Chun;
Tu, Chong-Xing;
Luo, Pei-Hua;
Zhu, Hong;
Zhu, Di-Feng;
Wu, Hong-Hai;
Zhou, Xing-Lu;
Lu, Wei;
He, Qiao-Jun;
Yang, Bo

Publication type:

Article

Synergistic efficacy of sorafenib and genistein in growth inhibition by down regulating angiogenic and survival factors and increasing apoptosis through upregulation of p53 and p21 in malignant neuroblastoma cells having N-Myc amplification or non-amplification

Published in:

Investigational New Drugs, 2010, v. 28, n. 6, p. 812, doi. 10.1007/s10637-009-9324-7

By:

Roy Choudhury, Subhasree;
Karmakar, Surajit;
Banik, Naren;
Ray, Swapan

Publication type:

Article

TAE226-mediated inhibition of focal adhesion kinase interferes with tumor angiogenesis and vasculogenesis.

Published in:

Investigational New Drugs, 2010, v. 28, n. 6, p. 825, doi. 10.1007/s10637-009-9326-5

By:

Schultze, Alexander;
Decker, Sebastian;
Otten, Jasmin;
Horst, Andrea;
Vohwinkel, Gabi;
Schuch, Gunter;
Bokemeyer, Carsten;
Loges, Sonja;
Fiedler, Walter

Publication type:

Article

Complete remission of ovarian cancer induced intractable malignant ascites with intraperitoneal bevacizumab. Immunological observations and a literature review.

Published in:

2010

By:

Bellati, Filippo;
Napoletano, Chiara;
Ruscito, Ilary;
Pastore, Maria;
Pernice, Milena;
Antonilli, Morena;
Nuti, Marianna;
Benedetti Panici, Pierluigi

Publication type:

Report

Erratum to: Antimetastatic activity of MONCPT in preclinical melanoma mice model.

Published in:

2010

By:

Yang, Xiao-Chun;
Tu, Chong-Xing;
Luo, Pei-Hua;
Zhu, Hong;
Zhu, Di-Feng;
Wu, Hong-Hai;
Zhou, Xing-Lu;
Lu, Wei;
He, Qiao-Jun;
Yang, Bo

Publication type:

Correction Notice

Effect of a Vitamin D3 derivative (B3CD) with postulated anti-cancer activity in an ovarian cancer animal model.

Published in:

2010

By:

Lange T;
Stuckey A;
Robison K;
Kim K;
Singh R;
Raker C;
Brard L

Publication type:

Journal Article

Intravenous administration of Reolysin®, a live replication competent RNA virus is safe in patients with advanced solid tumors.

Published in:

2010

By:

Gollamudi R;
Ghalib MH;
Desai KK;
Chaudhary I;
Wong B;
Einstein M;
Coffey M;
Gill GM;
Mettinger K;
Mariadason JM;
Mani S;
Goel S

Publication type:

Journal Article

Synthesis and biological properties of oxazolinodaunorubicin-a new derivative of daunorubicin with a modified daunosamine moiety.

Published in:

2010

By:

Lukawska M;
Wietrzyk J;
Opolski A;
Oszczapowicz J;
Oszczapowicz I

Publication type:

Journal Article

Effect of a Vitamin D<sub>3</sub> derivative (B3CD) with postulated anti-cancer activity in an ovarian cancer animal model.

Published in:

Investigational New Drugs, 2010, v. 28, n. 5, p. 543, doi. 10.1007/s10637-009-9284-y

By:

Lange, Thilo;
Stuckey, Ashley;
Robison, Katina;
Kim, Kyu;
Singh, Rakesh;
Raker, Christina;
Brard, Laurent

Publication type:

Article

Phase II study of darinaparsin in patients with advanced hepatocellular carcinoma.

Published in:

Investigational New Drugs, 2010, v. 28, n. 5, p. 670, doi. 10.1007/s10637-009-9286-9

By:

Wu, Jennifer;
Henderson, Charles;
Feun, Lynn;
Veldhuizen, Peter;
Gold, Philip;
Zheng, Hui;
Ryan, Theresa;
Blaszkowsky, Lawrence;
Chen, HaoBin;
Costa, Max;
Rosenzweig, Barry;
Nierodzik, MaryLynn;
Hochster, Howard;
Muggia, Franco;
Abbadessa, Giovanni;
Lewis, Jonathan;
Zhu, Andrew

Publication type:

Article

Nelfinavir induces mitochondria protection by ERK1/2-mediated mcl-1 stabilization that can be overcome by sorafenib.

Published in:

Investigational New Drugs, 2010, v. 28, n. 5, p. 535, doi. 10.1007/s10637-009-9281-1

By:

Brüning, Ansgar;
Burger, Petra;
Vogel, Marianne;
Gingelmaier, Andrea;
Friese, Klaus;
Burges, Alexander

Publication type:

Article

A phase I trial of imexon, a pro-oxidant, in combination with docetaxel for the treatment of patients with advanced breast, non-small cell lung and prostate cancer.

Published in:

Investigational New Drugs, 2010, v. 28, n. 5, p. 634, doi. 10.1007/s10637-009-9273-1

By:

Moulder, Stacy;
Dhillon, Navneet;
Ng, Chaan;
Hong, David;
Wheler, Jennifer;
Naing, Aung;
Tse, Susan;
La Paglia, Amy;
Dorr, Robert;
Hersh, Evan;
Boytim, Michelle;
Kurzrock, Razelle

Publication type:

Article

Sunitinib inducing tumor lysis syndrome in a patient treated for renal carcinoma.

Published in:

2010

By:

Michels, Judith;
Lassau, Nathalie;
Gross-Goupil, Marine;
Massard, Christophe;
Mejean, Arnaud;
Escudier, Bernard

Publication type:

Report

Anti-tumor effects of nitrosylcobalamin against spontaneous tumors in dogs.

Published in:

2010

By:

Bauer, Joseph;
Frye, Gerald;
Bahr, Anne;
Gieg, Jennifer;
Brofman, Peter

Publication type:

Report

Intravenous administration of Reolysin®, a live replication competent RNA virus is safe in patients with advanced solid tumors.

Published in:

Investigational New Drugs, 2010, v. 28, n. 5, p. 641, doi. 10.1007/s10637-009-9279-8

By:

Gollamudi, Radharani;
Ghalib, Mohammad;
Desai, Kavita;
Chaudhary, Imran;
Wong, Benny;
Einstein, Mark;
Coffey, Matthew;
Gill, George;
Mettinger, Karl;
Mariadason, John;
Mani, Sridhar;
Goel, Sanjay

Publication type:

Article

Phase II study of gemcitabine in combination with vinorelbine versus gemcitabine followed by vinorelbine for metastatic breast cancer.

Published in:

Investigational New Drugs, 2010, v. 28, n. 5, p. 659, doi. 10.1007/s10637-009-9285-x

By:

Park, In;
Ro, Jungsil;
Lee, Keun;
Kim, Shi;
Yun, Young;
Nam, Byung

Publication type:

Article

A phase I pharmacokinetic and pharmacodynamic study of CKD-732, an antiangiogenic agent, in patients with refractory solid cancer.

Published in:

Investigational New Drugs, 2010, v. 28, n. 5, p. 650, doi. 10.1007/s10637-009-9287-8

By:

Shin, Sang;
Jeung, Hei-Cheul;
Ahn, Joong;
Rha, Sun;
Roh, Jae;
Park, Kyung;
Kim, Dal-Hyun;
Kim, Chin;
Chung, Hyun

Publication type:

Article

Dietary supplementation of silymarin protects against chemically induced nephrotoxicity, inflammation and renal tumor promotion response.

Published in:

2010

By:

Kaur, Gurpreet;
Athar, Mohammad;
Alam, M.

Publication type:

Report

An in vitro study, evaluating the effect of sunitinib and/or lapatinib on two glioma cell lines.

Published in:

Investigational New Drugs, 2010, v. 28, n. 5, p. 554, doi. 10.1007/s10637-009-9290-0

By:

Giannopoulou, Efstathia;
Dimitropoulos, Konstantinos;
Argyriou, Andreas;
Koutras, Angelos;
Dimitrakopoulos, Fotinos;
Kalofonos, Haralabos

Publication type:

Article

Development of a new fully human anti-CD20 monoclonal antibody for the treatment of B-cell malignancies.

Published in:

Investigational New Drugs, 2010, v. 28, n. 5, p. 561, doi. 10.1007/s10637-009-9291-z

By:

Bornstein, Gadi;
Quéva, Christophe;
Tabrizi, Mohammad;
Abbema, Anne;
Chavez, Carlos;
Wang, Ping;
Foord, Orit;
Ahluwalia, Kiran;
Laing, Naomi;
Raja, Sandhya;
Wen, Shenghua;
Green, Larry;
Yang, Xiaodong;
Webster, Carl;
Stewart, Ross;
Blakey, David

Publication type:

Article

The induction of senescence-like growth arrest by protein kinase C-activating diterpene esters in solid tumor cells.

Published in:

Investigational New Drugs, 2010, v. 28, n. 5, p. 575, doi. 10.1007/s10637-009-9292-y

By:

Mason, Sharon;
Cozzi, Sarah-Jane;
Pierce, Carly;
Pavey, Sandra;
Parsons, Peter;
Boyle, Glen

Publication type:

Article

Triphenyltin(IV) 2-[( E)-2-(aryl)-1-diazenyl]benzoates as anticancer drugs: synthesis, structural characterization, in vitro cytotoxicity and study of its influence towards the mechanistic role of some key enzymes.

Published in:

Investigational New Drugs, 2010, v. 28, n. 5, p. 587, doi. 10.1007/s10637-009-9293-x

By:

Basu Baul, Tushar;
Paul, Anup;
Pellerito, Lorenzo;
Scopelliti, Michelangelo;
Singh, Palwinder;
Verma, Pooja;
Vos, Dick

Publication type:

Article