Found: 29
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The antitumor efficacy of monomeric disintegrin obtustatin in S-180 sarcoma mouse model.
- Published in:
- Investigational New Drugs, 2019, v. 37, n. 5, p. 1044, doi. 10.1007/s10637-019-00734-2
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- Article
Lopinavir-NO, a nitric oxide-releasing HIV protease inhibitor, suppresses the growth of melanoma cells in vitro and in vivo.
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- Investigational New Drugs, 2019, v. 37, n. 5, p. 1014, doi. 10.1007/s10637-019-00733-3
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- Article
A phase I study of the antibody drug conjugate ASG-5ME, an SLC44A4-targeting antibody carrying auristatin E, in metastatic castration-resistant prostate cancer.
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- Investigational New Drugs, 2019, v. 37, n. 5, p. 1052, doi. 10.1007/s10637-019-00731-5
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- Article
Modified ingenol semi-synthetic derivatives from Euphorbia tirucalli induce cytotoxicity on a large panel of human cancer cell lines.
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- Investigational New Drugs, 2019, v. 37, n. 5, p. 1029, doi. 10.1007/s10637-019-00728-0
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The rhenium(I)-diselenoether anticancer drug targets ROS, TGF-β1, VEGF-A, and IGF-1 in an in vitro experimental model of triple-negative breast cancers.
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- Investigational New Drugs, 2019, v. 37, n. 5, p. 973, doi. 10.1007/s10637-019-00727-1
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Nifuroxazide induces apoptosis, inhibits cell migration and invasion in osteosarcoma.
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- Investigational New Drugs, 2019, v. 37, n. 5, p. 1006, doi. 10.1007/s10637-019-00724-4
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- Article
Human antigen R and drug resistance in tumors.
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- Investigational New Drugs, 2019, v. 37, n. 5, p. 1107, doi. 10.1007/s10637-018-00723-x
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In vitro and in vivo cytotoxic activity and human serum albumin interaction for a methoxy-styryl-thiosemicarbazone.
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- Investigational New Drugs, 2019, v. 37, n. 5, p. 994, doi. 10.1007/s10637-018-00722-y
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- Article
Bispecific anti-CD3 x anti-B7-H3 antibody mediates T cell cytotoxic ability to human melanoma in vitro and in vivo.
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- Investigational New Drugs, 2019, v. 37, n. 5, p. 1036, doi. 10.1007/s10637-018-00719-7
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Biodistribution, pharmacokinetics and radioimmunotherapy of <sup>188</sup>Re-cetuximab in NCI-H292 human lung tumor-bearing nude mice.
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- Investigational New Drugs, 2019, v. 37, n. 5, p. 961, doi. 10.1007/s10637-018-00718-8
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- Article
The availability of drug by liposomal drug delivery: Individual kinetics and tissue distribution of encapsulated and released drug in mice after administration of PEGylated liposomal prednisolone phosphate.
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- Investigational New Drugs, 2019, v. 37, n. 5, p. 890, doi. 10.1007/s10637-018-0708-4
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- Article
Significant differences on submission lag following regulation reform for registration of novel therapeutic drugs in Taiwan.
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- Investigational New Drugs, 2019, v. 37, n. 5, p. 1094, doi. 10.1007/s10637-018-00715-x
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- Article
MiR-181a, a new regulator of TGF-β signaling, can promote cell migration and proliferation in gastric cancer.
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- Investigational New Drugs, 2019, v. 37, n. 5, p. 923, doi. 10.1007/s10637-018-0695-5
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- Article
The role of oxidative stress in 63 T-induced cytotoxicity against human lung cancer and normal lung fibroblast cell lines.
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- Investigational New Drugs, 2019, v. 37, n. 5, p. 849, doi. 10.1007/s10637-018-0704-8
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- Article
Screening, identification of prostate cancer urinary biomarkers and verification of important spots.
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- Investigational New Drugs, 2019, v. 37, n. 5, p. 935, doi. 10.1007/s10637-018-0709-3
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- Article
Sensitization of colorectal cancer to irinotecan therapy by PARP inhibitor rucaparib.
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- Investigational New Drugs, 2019, v. 37, n. 5, p. 948, doi. 10.1007/s10637-018-00717-9
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- Article
A phase I study of ontuxizumab, a humanized monoclonal antibody targeting endosialin, in Japanese patients with solid tumors.
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- Investigational New Drugs, 2019, v. 37, n. 5, p. 1061, doi. 10.1007/s10637-018-0713-7
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- Article
The cellular effects of novel triazine nitrogen mustards in glioblastoma LBC3, LN-18 and LN-229 cell lines.
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- Investigational New Drugs, 2019, v. 37, n. 5, p. 984, doi. 10.1007/s10637-018-0712-8
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- Article
A mediator of phosphorylated Smad2/3, evodiamine, in the reversion of TAF-induced EMT in normal colonic epithelial cells.
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- Investigational New Drugs, 2019, v. 37, n. 5, p. 865, doi. 10.1007/s10637-018-0702-x
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- Article
Caffeic acid phenethyl ester exerts apoptotic and oxidative stress on human multiple myeloma cells.
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- Investigational New Drugs, 2019, v. 37, n. 5, p. 837, doi. 10.1007/s10637-018-0701-y
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- Article
The novel PI3K inhibitor S1 synergizes with sorafenib in non-small cell lung cancer cells involving the Akt-S6 signaling.
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- Investigational New Drugs, 2019, v. 37, n. 5, p. 828, doi. 10.1007/s10637-018-0698-2
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- Article
Modulator of the PI3K/Akt oncogenic pathway affects mTOR complex 2 in human adenocarcinoma cells.
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- Investigational New Drugs, 2019, v. 37, n. 5, p. 902, doi. 10.1007/s10637-018-0705-7
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- Article
MICONIDINE acetate, a new selective and cytotoxic compound with synergic potential, induces cell cycle arrest and apoptosis in leukemia cells.
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- Investigational New Drugs, 2019, v. 37, n. 5, p. 912, doi. 10.1007/s10637-018-0694-6
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- Article
A novel tetravalent bispecific antibody targeting programmed death 1 and tyrosine-protein kinase Met for treatment of gastric cancer.
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- Investigational New Drugs, 2019, v. 37, n. 5, p. 876, doi. 10.1007/s10637-018-0689-3
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- Article
The bispecific anti-CD3 × anti-CD155 antibody mediates T cell immunotherapy for human prostate cancer.
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- Investigational New Drugs, 2019, v. 37, n. 5, p. 810, doi. 10.1007/s10637-018-0683-9
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- Article
Chemotherapy in pregnancy: exploratory study of the effects of paclitaxel on the expression of placental drug transporters.
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- Investigational New Drugs, 2019, v. 37, n. 5, p. 1075, doi. 10.1007/s10637-018-0677-7
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The drug lag and associated factors for orphan anticancer drugs in Japan compared to the United States.
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- Investigational New Drugs, 2019, v. 37, n. 5, p. 1086, doi. 10.1007/s10637-018-0612-y
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- Article
Lurbinectedin (PM01183), a selective inhibitor of active transcription, effectively eliminates both cancer cells and cancer stem cells in preclinical models of uterine cervical cancer.
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- Investigational New Drugs, 2019, v. 37, n. 5, p. 818, doi. 10.1007/s10637-018-0686-6
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- Article
A novel humanized anti-PD-1 monoclonal antibody potentiates therapy in oral squamous cell carcinoma.
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- Investigational New Drugs, 2019, v. 37, n. 5, p. 799, doi. 10.1007/s10637-018-0678-6
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- Article