Found: 36
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A phase I study of intravenous aflibercept with FOLFIRI in Japanese patients with previously treated metastatic colorectal cancer.
- Published in:
- Investigational New Drugs, 2013, v. 31, n. 4, p. 910, doi. 10.1007/s10637-012-9895-6
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- Publication type:
- Article
Monitoring the effects of bevacizumab beyond progression in a murine colorectal cancer model: a functional imaging approach.
- Published in:
- Investigational New Drugs, 2013, v. 31, n. 4, p. 881, doi. 10.1007/s10637-012-9920-9
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- Publication type:
- Article
Phase Ib trial of the oral angiogenesis inhibitor pazopanib administered concurrently with erlotinib.
- Published in:
- Investigational New Drugs, 2013, v. 31, n. 4, p. 891, doi. 10.1007/s10637-012-9887-6
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- Publication type:
- Article
Evaluation of the pharmacodynamics and pharmacokinetics of the PARP inhibitor olaparib: a Phase I multicentre trial in patients scheduled for elective breast cancer surgery.
- Published in:
- Investigational New Drugs, 2013, v. 31, n. 4, p. 949, doi. 10.1007/s10637-012-9922-7
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- Publication type:
- Article
Safety and pharmacokinetics of the antisense oligonucleotide (ASO) LY2181308 as a single-agent or in combination with idarubicin and cytarabine in patients with refractory or relapsed acute myeloid leukemia (AML)
- Published in:
- 2013
- By:
- Publication type:
- Journal Article
Functional and molecular characterization of kinin B and B receptors in human bladder cancer: implication of the PI3Kγ pathway.
- Published in:
- 2013
- By:
- Publication type:
- Journal Article
Sonic hedgehog antagonists induce cell death in acute myeloid leukemia cells with the presence of lipopolysaccharides, tumor necrosis factor-α, or interferons.
- Published in:
- 2013
- By:
- Publication type:
- Journal Article
First-in-human phase 1/2a trial of CRLX101, a cyclodextrin-containing polymer-camptothecin nanopharmaceutical in patients with advanced solid tumor malignancies.
- Published in:
- Investigational New Drugs, 2013, v. 31, n. 4, p. 986, doi. 10.1007/s10637-012-9921-8
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- Publication type:
- Article
Phase I trial of bortezomib and dacarbazine in melanoma and soft tissue sarcoma.
- Published in:
- Investigational New Drugs, 2013, v. 31, n. 4, p. 937, doi. 10.1007/s10637-012-9913-8
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- Publication type:
- Article
A phase I study of sorafenib, oxaliplatin and 2 days of high dose capecitabine in advanced pancreatic and biliary tract cancer: a Wisconsin oncology network study.
- Published in:
- Investigational New Drugs, 2013, v. 31, n. 4, p. 943, doi. 10.1007/s10637-012-9916-5
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- Publication type:
- Article
Tetra-O-methyl nordihydroguaiaretic acid, an inhibitor of Sp1-mediated survivin transcription, induces apoptosis and acts synergistically with chemo-radiotherapy in glioblastoma cells.
- Published in:
- Investigational New Drugs, 2013, v. 31, n. 4, p. 858, doi. 10.1007/s10637-012-9917-4
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- Publication type:
- Article
Therapeutic efficacy of Re-liposome in a C26 murine colon carcinoma solid tumor model.
- Published in:
- Investigational New Drugs, 2013, v. 31, n. 4, p. 801, doi. 10.1007/s10637-012-9906-7
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- Publication type:
- Article
Phase I study of oral CP-4126, a gemcitabine derivative, in patients with advanced solid tumors.
- Published in:
- Investigational New Drugs, 2013, v. 31, n. 4, p. 959, doi. 10.1007/s10637-013-9925-z
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- Publication type:
- Article
Sustained inhibition of deacetylases is required for the antitumor activity of the histone deactylase inhibitors panobinostat and vorinostat in models of colorectal cancer.
- Published in:
- Investigational New Drugs, 2013, v. 31, n. 4, p. 845, doi. 10.1007/s10637-012-9914-7
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- Publication type:
- Article
A phase I trial of KX2-391, a novel non-ATP competitive substrate-pocket- directed SRC inhibitor, in patients with advanced malignancies.
- Published in:
- Investigational New Drugs, 2013, v. 31, n. 4, p. 967, doi. 10.1007/s10637-013-9929-8
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- Publication type:
- Article
Preclinical antitumor activity of a nanoparticulate SN38.
- Published in:
- Investigational New Drugs, 2013, v. 31, n. 4, p. 871, doi. 10.1007/s10637-012-9919-2
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- Publication type:
- Article
Safety and pharmacokinetics of the antisense oligonucleotide (ASO) LY2181308 as a single-agent or in combination with idarubicin and cytarabine in patients with refractory or relapsed acute myeloid leukemia (AML).
- Published in:
- Investigational New Drugs, 2013, v. 31, n. 4, p. 1023, doi. 10.1007/s10637-013-9935-x
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- Publication type:
- Article
Erratum to: Phase I trial of bortezomib and dacarbazine in melanoma and soft tissue sarcoma.
- Published in:
- 2013
- By:
- Publication type:
- Correction Notice
A phase 2 multicenter study of tivantinib (ARQ 197) monotherapy in patients with relapsed or refractory germ cell tumors.
- Published in:
- Investigational New Drugs, 2013, v. 31, n. 4, p. 1016, doi. 10.1007/s10637-013-9934-y
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- Publication type:
- Article
Sonic hedgehog antagonists induce cell death in acute myeloid leukemia cells with the presence of lipopolysaccharides, tumor necrosis factor-α, or interferons.
- Published in:
- Investigational New Drugs, 2013, v. 31, n. 4, p. 823, doi. 10.1007/s10637-012-9908-5
- By:
- Publication type:
- Article
Opioid growth factor (OGF) for hepatoblastoma: a novel non-toxic treatment.
- Published in:
- 2013
- By:
- Publication type:
- Report
A randomized, double-blind, placebo-controlled, Phase II study with and without enzastaurin in combination with docetaxel-based chemotherapy in patients with castration-resistant metastatic prostate cancer.
- Published in:
- Investigational New Drugs, 2013, v. 31, n. 4, p. 1044, doi. 10.1007/s10637-013-9940-0
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- Publication type:
- Article
Effect of selection of QTc formula on eligibility of cancer patients for phase I clinical trials.
- Published in:
- Investigational New Drugs, 2013, v. 31, n. 4, p. 1056, doi. 10.1007/s10637-012-9909-4
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- Publication type:
- Article
LY2801653 is an orally bioavailable multi-kinase inhibitor with potent activity against MET, MST1R, and other oncoproteins, and displays anti-tumor activities in mouse xenograft models.
- Published in:
- Investigational New Drugs, 2013, v. 31, n. 4, p. 833, doi. 10.1007/s10637-012-9912-9
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- Publication type:
- Article
Phase II study to assess the efficacy, safety and tolerability of the mitotic spindle kinesin inhibitor AZD4877 in patients with recurrent advanced urothelial cancer.
- Published in:
- Investigational New Drugs, 2013, v. 31, n. 4, p. 1001, doi. 10.1007/s10637-013-9926-y
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- Publication type:
- Article
Cardiac glycosides in cancer therapy: from preclinical investigations towards clinical trials.
- Published in:
- Investigational New Drugs, 2013, v. 31, n. 4, p. 1087, doi. 10.1007/s10637-013-9984-1
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- Publication type:
- Article
A phase I dose-escalation study of intravenous panobinostat in patients with lymphoma and solid tumors.
- Published in:
- Investigational New Drugs, 2013, v. 31, n. 4, p. 974, doi. 10.1007/s10637-013-9930-2
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- Publication type:
- Article
A phase II study of cediranib (AZD 2171) in treatment naive patients with progressive unresectable recurrent or metastatic renal cell carcinoma. A trial of the PMH phase 2 consortium.
- Published in:
- Investigational New Drugs, 2013, v. 31, n. 4, p. 1008, doi. 10.1007/s10637-013-9931-1
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- Publication type:
- Article
Risk of hand-foot skin reaction with the novel multikinase inhibitor regorafenib: a meta-analysis.
- Published in:
- Investigational New Drugs, 2013, v. 31, n. 4, p. 1078, doi. 10.1007/s10637-013-9977-0
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- Publication type:
- Article
Phase Ib trial of the oral angiogenesis inhibitor pazopanib administered concurrently with pemetrexed in patients with advanced solid tumors.
- Published in:
- Investigational New Drugs, 2013, v. 31, n. 4, p. 927, doi. 10.1007/s10637-012-9900-0
- By:
- Publication type:
- Article
Maintenance single-agent bevacizumab or observation after first-line chemotherapy in patients with metastatic colorectal cancer: a multicenter retrospective study.
- Published in:
- Investigational New Drugs, 2013, v. 31, n. 4, p. 1035, doi. 10.1007/s10637-013-9936-9
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- Publication type:
- Article
A phase 1 study of gemcitabine combined with dasatinib in patients with advanced solid tumors.
- Published in:
- Investigational New Drugs, 2013, v. 31, n. 4, p. 918, doi. 10.1007/s10637-012-9898-3
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- Publication type:
- Article
Potential factors correlating to the PMDA's decision to waive Japanese Phase 2 and 3 studies for oncology drugs New Drug Application in Japan.
- Published in:
- Investigational New Drugs, 2013, v. 31, n. 4, p. 1051, doi. 10.1007/s10637-012-9911-x
- By:
- Publication type:
- Article
Ipilimumab associated hepatitis: imaging and clinicopathologic findings.
- Published in:
- 2013
- By:
- Publication type:
- Report
Functional and molecular characterization of kinin B and B receptors in human bladder cancer: implication of the PI3Kγ pathway.
- Published in:
- Investigational New Drugs, 2013, v. 31, n. 4, p. 812, doi. 10.1007/s10637-012-9907-6
- By:
- Publication type:
- Article
A phase I, open-label, single-arm study for QT assessment of eribulin mesylate in patients with advanced solid tumors.
- Published in:
- Investigational New Drugs, 2013, v. 31, n. 4, p. 900, doi. 10.1007/s10637-012-9893-8
- By:
- Publication type:
- Article