Works in Drug & Chemical Toxicology, 2022, Vol 45, Issue 5

Results: 48

Distribution, metabolism, excretion, and toxicity of implanted silver: a review.

Published in:

Drug & Chemical Toxicology, 2022, v. 45, n. 5, p. 2388, doi. 10.1080/01480545.2021.1950167

By:

Hadrup, Niels;
Sharma, Anoop K.;
Jacobsen, Nicklas R.;
Loeschner, Katrin

Publication type:

Article

Effects of quetiapine administration on sperm quality and testicular histology.

Published in:

Drug & Chemical Toxicology, 2022, v. 45, n. 5, p. 2379, doi. 10.1080/01480545.2021.1946558

By:

Korkut Celikates, Busra;
Kilic, Volkan;
Atli-Eklioglu, Ozlem;
Baysal, Merve;
Aydogan-Kılıc, Gozde;
Ucarcan, Seyda;
Ilgin, Sinem

Publication type:

Article

Silver nanoparticles' impact on the gene expression of the cytosolic adaptor MyD-88 and the interferon regulatory factor IRF in the gills and digestive gland of mytilus galloprovincialis.

Published in:

Drug & Chemical Toxicology, 2022, v. 45, n. 5, p. 2371, doi. 10.1080/01480545.2021.1945128

By:

Ben Younes, Ridha;
Bouallegui, Younes;
Fezai, Olfa;
Mezni, Amine;
Touaylia, Samir;
Oueslati, Ridha

Publication type:

Article

Lagerstroemia speciosa (L.) Pers., ethanolic leaves extract attenuates dapsone-induced liver inflammation in rats.

Published in:

Drug & Chemical Toxicology, 2022, v. 45, n. 5, p. 2361, doi. 10.1080/01480545.2021.1945079

By:

Rohit Singh, Thakur;
Ezhilarasan, Devaraj

Publication type:

Article

Glabridin attenuates paracetamol-induced liver injury in mice via CYP2E1-mediated inhibition of oxidative stress.

Published in:

Drug & Chemical Toxicology, 2022, v. 45, n. 5, p. 2352, doi. 10.1080/01480545.2021.1945004

By:

Bhatt, Shipra;
Sharma, Ankita;
Dogra, Ashish;
Sharma, Priyanka;
Kumar, Amit;
Kotwal, Pankul;
Bag, Swarnendu;
Misra, Prashant;
Singh, Gurdarshan;
Kumar, Ajay;
Sangwan, Payare Lal;
Nandi, Utpal

Publication type:

Article

Study of cardioprotective activity of the methanolic extract of the aerial parts of Bauhinia madagascariensis compared to Bauhinia purpurea against adrenaline-induced myocardial toxicity in rats.

Published in:

Drug & Chemical Toxicology, 2022, v. 45, n. 5, p. 2341, doi. 10.1080/01480545.2021.1942486

By:

Aziz, Fayza Tawfiek Abdl;
Sanad, Fatma Abdel-Azim;
Temraz, Abeer;
El-Tantawy, Walid Hamdy;
Hassan, Madiha Amin

Publication type:

Article

Therapeutic effects of thymoquinone or capsaicin on acrylamide-induced reproductive toxicity in rats mediated by their effect on oxidative stress, inflammation, and tight junction integrity.

Published in:

Drug & Chemical Toxicology, 2022, v. 45, n. 5, p. 2328, doi. 10.1080/01480545.2021.1942485

By:

Abd Al Haleem, Ekram Nemr;
Hasan, Walaa Yousef Soliman;
Arafa, Hossam Mohamed Mohamed

Publication type:

Article

The effects of minocycline in improving of methamphetamine withdrawal syndrome in male mice.

Published in:

Drug & Chemical Toxicology, 2022, v. 45, n. 5, p. 2319, doi. 10.1080/01480545.2021.1942484

By:

Ghavimi, Hamed;
Bayani Ershadi, Amir Sasan;
Dastvar, Samira;
Hosseini, Mir-Jamal

Publication type:

Article

Borassus flabellifer Linn haustorium methanol extract mitigates fluoride-induced apoptosis by enhancing Nrf2/Haeme oxygenase 1 –dependent glutathione metabolism in intestinal epithelial cells.

Published in:

Drug & Chemical Toxicology, 2022, v. 45, n. 5, p. 2269, doi. 10.1080/01480545.2021.1926476

By:

Job, Joice Tom;
Rajagopal, Rajakrishnan;
Alfarhan, Ahmed;
Narayanankutty, Arunaksharan

Publication type:

Article

Investigation of genotoxic effects of rhododendron honey using three mammalian bioassays in vivo.

Published in:

Drug & Chemical Toxicology, 2022, v. 45, n. 5, p. 2301, doi. 10.1080/01480545.2021.1935421

By:

Rasgele, Pinar Goc;
Gokalp, Fulya Dilek;
Kaya, Salih Tunc;
Kekecoglu, Meral;
Acar, Merve Kambur

Publication type:

Article

The impact of filtered water-pipe smoke on healthy versus cancer cells and their neurodegenerative role on AMPA receptor.

Published in:

Drug & Chemical Toxicology, 2022, v. 45, n. 5, p. 2292, doi. 10.1080/01480545.2021.1935397

By:

Hawash, Mohammed;
Qneibi, Mohammad;
Jaradat, Nidal;
Abualhasan, Murad;
Amer, Johnny;
Amer, EL-Hamouz;
Ibraheem, Tasneem;
Hindieh, Siham;
Tarazi, Sama;
Sobuh, Shorooq

Publication type:

Article

Combined effect of fulvestrant and low dose BPA: comparative implications on EMT, apoptosis, and TGF-β1 signaling in HepG2 cells.

Published in:

Drug & Chemical Toxicology, 2022, v. 45, n. 5, p. 2285, doi. 10.1080/01480545.2021.1935368

By:

Öz, Esin;
Tüylü Küçükkılınç, Tuba

Publication type:

Article

Resveratrol-mediated cardioprotection against myocardial ischemia-reperfusion injury was revoked by statin-induced mitochondrial alterations.

Published in:

Drug & Chemical Toxicology, 2022, v. 45, n. 5, p. 2276, doi. 10.1080/01480545.2021.1929285

By:

C. Vedarathinam, Ramalingam;
Rajkumar, Yogeshwari;
Vetriselvan, Priya;
Prem, Priyanka N.;
Ganapathy, Angammai;
Kurian, Gino A.

Publication type:

Article

Dichlorophene activates aryl hydrocarbon receptor (AhR) and indoleamine 2, 3-dioxygenase 1 (IDO1) to mediate splenotoxicity in rat.

Published in:

Drug & Chemical Toxicology, 2022, v. 45, n. 5, p. 2311, doi. 10.1080/01480545.2021.1935435

By:

Banerjee, Oly;
Singh, Siddhartha;
Prasad, Shilpi K;
Ray, Dibyendu;
Banerjee, Maitrayee;
Pal, Swagata;
Kundu, Sudipta;
Maji, Bithin Kumar;
Mukherjee, Sandip

Publication type:

Article

Treatment with human umbilical cord blood serum in a gentamicin-induced nephrotoxicity model in rats.

Published in:

Drug & Chemical Toxicology, 2022, v. 45, n. 5, p. 2262, doi. 10.1080/01480545.2021.1926475

By:

Mirazi, Naser;
Baharvand, Fatemeh;
Moghadasali, Reza;
Nourian, Alireza;
Hosseini, Abdolkarim

Publication type:

Article

Ameliorative role of inducible nitric oxide synthase inhibitors against sodium arsenite-induced renal and hepatic dysfunction in rats.

Published in:

Drug & Chemical Toxicology, 2022, v. 45, n. 5, p. 2255, doi. 10.1080/01480545.2021.1926109

By:

Kumar Sharma, Ashwani;
Kaur, Anmoldeep;
Kaur, Tajpreet;
Kaur, Sarabjit;
Pathak, Devendra;
Singh, Amrit Pal

Publication type:

Article

Chemical characterization of tobacco-free "modern" oral nicotine pouches and their position on the toxicant and risk continuums.

Published in:

Drug & Chemical Toxicology, 2022, v. 45, n. 5, p. 2246, doi. 10.1080/01480545.2021.1925691

By:

Azzopardi, David;
Liu, Chuan;
Murphy, James

Publication type:

Article

Rosuvastatin exposure in female Wistar rats alters uterine contractility and do not show evident (anti)estrogenic effects.

Published in:

Drug & Chemical Toxicology, 2022, v. 45, n. 5, p. 2233, doi. 10.1080/01480545.2021.1919139

By:

de Barros, Jorge Willian Franco;
Villela e Silva, Patrícia;
da Silva, Gustavo Venâncio;
da Silva, Katiussia Pinho;
Borges, Cibele dos Santos;
Mueller, André;
Valencise, Lethícia;
Pupo, André Sampaio;
Kempinas, Wilma De Grava

Publication type:

Article

Synergistic hepatoprotective effects of ω-3 and ω-6 fatty acids from Indian flax and sesame seed oils against CCl<sub>4</sub>-induced oxidative stress-mediated liver damage in rats.

Published in:

Drug & Chemical Toxicology, 2022, v. 45, n. 5, p. 2221, doi. 10.1080/01480545.2021.1917496

By:

Gurumallu, Sunil Chikkalakshmipura;
Aqeel, Tareq;
Bhaskar, Ashwini;
Chandramohan, Kannan;
Javaraiah, Rajesha

Publication type:

Article

Verbascoside inhibits paraquate-induced pulmonary toxicity via modulating oxidative stress, inflammation, apoptosis and DNA damage in A549 cell.

Published in:

Drug & Chemical Toxicology, 2022, v. 45, n. 5, p. 2212, doi. 10.1080/01480545.2021.1917467

By:

Khorashadizadeh, Nastaran;
Neamati, Ali;
Moshiri, Mohammad;
Etemad, Leila

Publication type:

Article

N<sup>ω</sup>-nitro-L-arginine, a nitric oxide synthase inhibitor, attenuates nickel-induced neurotoxicity.

Published in:

Drug & Chemical Toxicology, 2022, v. 45, n. 5, p. 2202, doi. 10.1080/01480545.2021.1917382

By:

Ijomone, Omamuyovwi M.;
Aluko, Oritoke M.;
Okoh, Comfort O. A.;
Ebokaiwe, Azubuike P.

Publication type:

Article

Subacute oral toxicity and bacterial mutagenicity of a mixture of Puerariae radix and Hizikia fusiforme extracts.

Published in:

Drug & Chemical Toxicology, 2022, v. 45, n. 5, p. 2193, doi. 10.1080/01480545.2021.1916176

By:

Youn, Soo Hyun;
Han, Chang-Kyun;
Suh, Jae Hyun;
Hyun, Sun Hee;
Kyung, Jong-Soo;
So, Seung-Ho;
Kim, Jong-Han;
Seo, Hwi Won

Publication type:

Article

Anticonvulsant effectiveness of scopolamine against soman-induced seizures in African green monkeys.

Published in:

Drug & Chemical Toxicology, 2022, v. 45, n. 5, p. 2185, doi. 10.1080/01480545.2021.1916171

By:

McDonough, John H.;
McMonagle, Joseph D.;
Capacio, Benedict R.

Publication type:

Article

There and back again: a dendrimer's tale.

Published in:

Drug & Chemical Toxicology, 2022, v. 45, n. 5, p. 2169, doi. 10.1080/01480545.2021.1915327

By:

Ziemba, Barbara;
Borowiec, Maciej;
Franiak-Pietryga, Ida

Publication type:

Article

Neuroprotective effects of dexpanthenol on streptozotocin-induced neuronal damage in rats.

Published in:

Drug & Chemical Toxicology, 2022, v. 45, n. 5, p. 2160, doi. 10.1080/01480545.2021.1914464

By:

Erdogan, Mumin Alper;
Yigitturk, Gurkan;
Erbas, Oytun;
Taskıran, Dilek

Publication type:

Article

Nebivolol alleviates liver damage caused by methotrexate via AKT1/Hif1α/eNOS signaling.

Published in:

Drug & Chemical Toxicology, 2022, v. 45, n. 5, p. 2153, doi. 10.1080/01480545.2021.1908759

By:

Pekgöz, Sakir;
Asci, Halil;
Erzurumlu, Yalcin;
Savran, Mehtap;
Ilhan, Ilter;
Hasseyid, Nursel;
Ciris, Metin

Publication type:

Article

Protective effect of chrysin, a flavonoid, on the genotoxic activity of carboplatin in mice.

Published in:

Drug & Chemical Toxicology, 2022, v. 45, n. 5, p. 2146, doi. 10.1080/01480545.2021.1908752

By:

Jan, Basit L.;
Ahmad, Ajaz;
Khan, Altaf;
Rehman, Muneeb U.;
Alkharfy, Khalid M.

Publication type:

Article

Neurotoxic responses of rainbow trout (Oncorhynchus mykiss) exposed to fipronil: multi-biomarker approach to illuminate the mechanism in brain.

Published in:

Drug & Chemical Toxicology, 2022, v. 45, n. 5, p. 2140, doi. 10.1080/01480545.2021.1908751

By:

Uçar, Arzu;
Özgeriş, Fatma Betül;
Parlak, Veysel;
Yeltekin, Aslı Çilingir;
Kocaman, Esat Mahmut;
Alak, Gonca;
Atamanalp, Muhammed

Publication type:

Article

Protective effects of resveratrol and avocado oil against paracetamol-induced hepatotoxicity in rats.

Published in:

Drug & Chemical Toxicology, 2022, v. 45, n. 5, p. 2131, doi. 10.1080/01480545.2021.1908716

By:

Gokkaya, Erdi Onur;
Yesilot, Sukriye;
Ozgocmen, Meltem;
Aslankoc, Rahime;
Aydin Acar, Cigdem

Publication type:

Article

Effects of ellagic acid in the testes of streptozotocin induced diabetic rats.

Published in:

Drug & Chemical Toxicology, 2022, v. 45, n. 5, p. 2123, doi. 10.1080/01480545.2021.1908714

By:

Akarca Dizakar, Saadet Özen;
Saribas, Gulistan Sanem;
Tekcan, Akın

Publication type:

Article

Identification and genotoxicity evaluation of potential impurities in rabeprazole sodium using in silico and in vitro analyses.

Published in:

Drug & Chemical Toxicology, 2022, v. 45, n. 5, p. 2116, doi. 10.1080/01480545.2021.1908712

By:

Du, Yi;
Wu, Yinnan;
Liu, Yang;
Meng, Changhong;
Tan, Li;
Cai, Tiantian;
Wang, Yuxin;
Lu, Yihong

Publication type:

Article

Genotoxicity evaluation of self-assembled-micelle inhibitory RNA-targeting amphiregulin (SAMiRNA-AREG), a novel siRNA nanoparticle for the treatment of fibrotic disease.

Published in:

Drug & Chemical Toxicology, 2022, v. 45, n. 5, p. 2109, doi. 10.1080/01480545.2021.1908003

By:

Kim, Hyeon-Young;
Kim, Tae Rim;
Kim, Sung-Hwan;
Kim, In-Hyeon;
Ko, Youngho;
Yun, Sungil;
Lee, In-Chul;
Park, Han-Oh;
Kim, Jong-Choon

Publication type:

Article

l-Theanine ameliorates motor deficit, mitochondrial dysfunction, and neurodegeneration against chronic tramadol induced rats model of Parkinson's disease.

Published in:

Drug & Chemical Toxicology, 2022, v. 45, n. 5, p. 2097, doi. 10.1080/01480545.2021.1907909

By:

Raj, Khadga;
Gupta, G. D.;
Singh, Shamsher

Publication type:

Article

Acute toxicity studies and protective effects of Cinnamon cassia bark extract in streptozotocin-induced diabetic rats.

Published in:

Drug & Chemical Toxicology, 2022, v. 45, n. 5, p. 2086, doi. 10.1080/01480545.2021.1907908

By:

Vijayakumar, K.;
Rengarajan, R. L.;
Suganthi, N.;
Prasanna, B.;
Velayuthaprabhu, S.;
Shenbagam, M.;
Vijaya Anand, A.

Publication type:

Article

Toxicological assessment of electronic cigarette vaping: an emerging threat to force health, readiness and resilience in the U.S. Army.

Published in:

Drug & Chemical Toxicology, 2022, v. 45, n. 5, p. 2049, doi. 10.1080/01480545.2021.1905657

By:

Williams, Marc A.;
Reddy, Gunda;
Quinn, Michael J.;
Millikan Bell, Amy

Publication type:

Article

Trends of acute drug and chemical toxicities in adults and adolescents in Tehran, Iran between 2012 and 2018: a retrospective chart review.

Published in:

Drug & Chemical Toxicology, 2022, v. 45, n. 5, p. 2039, doi. 10.1080/01480545.2021.1903486

By:

Hadeiy, Seyed Kaveh;
Parhizgar, Parinaz;
Hassanian-Moghaddam, Hossein;
Zamani, Nasim;
Khoshkar, Ali;
Kolahi, Ali-Asghar;
Amirabadizadeh, Alireza;
Rezaei, Omidvar

Publication type:

Article

The comparison of the effect of Origanum vulgare L. extract and vitamin C on the gentamycin-induced nephrotoxicity in rats.

Published in:

Drug & Chemical Toxicology, 2022, v. 45, n. 5, p. 2031, doi. 10.1080/01480545.2021.1895826

By:

Raeeszadeh, Mahdieh;
Rezaee, Mahtab;
Akbari, Abolfazl;
Khademi, Nadia

Publication type:

Article

Linalool exhibits therapeutic and protective effects in a rat model of doxorubicin-induced kidney injury by modulating oxidative stress.

Published in:

Drug & Chemical Toxicology, 2022, v. 45, n. 5, p. 2024, doi. 10.1080/01480545.2021.1894751

By:

Altinoz, Eyup;
Oner, Zulal;
Elbe, Hulya;
Uremis, Nuray;
Uremis, Muhammed

Publication type:

Article

Morel mushroom, Morchella from Kashmir Himalaya: a potential source of therapeutically useful bioactives that possess free radical scavenging, anti-inflammatory, and arthritic edema-inhibiting activities.

Published in:

Drug & Chemical Toxicology, 2022, v. 45, n. 5, p. 2014, doi. 10.1080/01480545.2021.1894750

By:

Ramya, Haridas;
Ravikumar, Korattuvalappil S.;
Fathimathu, Zuhara;
Janardhanan, Kainoor K.;
Ajith, Thekkuttuparambil A.;
Shah, Manzoor Ahmad;
Farooq, Ramona;
Reshi, Zafar A.

Publication type:

Article

Evaluation of the non-clinical toxicity of an antiparasitic agent: diminazene aceturate.

Published in:

Drug & Chemical Toxicology, 2022, v. 45, n. 5, p. 2003, doi. 10.1080/01480545.2021.1894741

By:

da Silva Oliveira, George Laylson;
da Silva, Ana Paula dos Santos C. L.

Publication type:

Article

Chronic intraperitoneal injection of polyethylene glycol 200 in mice induces hippocampal neuroinflammation.

Published in:

Drug & Chemical Toxicology, 2022, v. 45, n. 5, p. 1995, doi. 10.1080/01480545.2021.1894738

By:

Freyssin, Aline;
Fauconneau, Bernard;
Chassaing, Damien;
Rioux Bilan, Agnès;
Page, Guylène

Publication type:

Article

Oral toxicity evaluation of gokshuradi guggulu, an ayurvedic formulation.

Published in:

Drug & Chemical Toxicology, 2022, v. 45, n. 5, p. 1986, doi. 10.1080/01480545.2021.1894725

By:

Wanjari, Manish M.;
Dey, Yadu Nandan;
Yadav, Mahendra;
Sharma, Deepti;
Srivastava, Bhavana;
Jamdagni, Shrirang B.;
Gaidhani, Sudesh N.;
Pawar, Sharad

Publication type:

Article

Prenatal exposure of bonny light crude oil induces embryotoxicity, impaired cognitive functions and cortico-hippocampal neurodegeneration on fetal outcomes of pregnant sprague-dawley rats.

Published in:

Drug & Chemical Toxicology, 2022, v. 45, n. 5, p. 1978, doi. 10.1080/01480545.2021.1894721

By:

Gbotolorun, S. C.;
Ezeife, C. C.;
Ogunlade, B.

Publication type:

Article

Synthetic pyrethroids common metabolite 3-phenoxybenzoic acid induces caspase-3 and Bcl-2 mediated apoptosis in human hepatocyte cells.

Published in:

Drug & Chemical Toxicology, 2022, v. 45, n. 5, p. 1971, doi. 10.1080/01480545.2021.1894720

By:

Guvenc, Dilek;
Inal, Sinem;
Kuruca, Nilufer;
Gokmen, Sedat;
Guvenc, Tolga

Publication type:

Article

The molecular interaction of human anti-apoptotic proteins and in silico ADMET, drug-likeness and toxicity computation of N-cyclohexylmethacrylamide.

Published in:

Drug & Chemical Toxicology, 2022, v. 45, n. 5, p. 1963, doi. 10.1080/01480545.2021.1894711

By:

Çankaya, Nevin;
Azarkan, Serap Yalçın;
Tanış, Emine

Publication type:

Article

Attenuation of lipid metabolic abnormalities, proinflammatory cytokines, and matrix metalloproteinase expression by biochanin-A in isoproterenol-induced myocardial infarction in rats.

Published in:

Drug & Chemical Toxicology, 2022, v. 45, n. 5, p. 1951, doi. 10.1080/01480545.2021.1894707

By:

Sangeethadevi, Govindasami;
V. V., Sathibabu Uddandrao;
Jansy Isabella, Rani Antony Rathinasamy;
Saravanan, Ganapathy;
Ponmurugan, Ponnusamy;
Chandrasekaran, Ponnusamy;
Sengottuvelu, Singaravel;
Vadivukkarasi, Sasikumar

Publication type:

Article

Flavonoid-rich fraction of Lasianthera africana leaves alleviates hepatotoxicity induced by carbon tetrachloride in Wistar rats.

Published in:

Drug & Chemical Toxicology, 2022, v. 45, n. 5, p. 1934, doi. 10.1080/01480545.2021.1892957

By:

Ekpo, Daniel Emmanuel;
Joshua, Parker Elijah;
Odiba, Arome Solomon;
Nwodo, Okwesilieze Fred Chiletugo

Publication type:

Article

Cocoyam (Colocasia esculenta) modulates some parameters of testosterone propionate-induced rat model of benign prostatic hyperplasia.

Published in:

Drug & Chemical Toxicology, 2022, v. 45, n. 5, p. 1923, doi. 10.1080/01480545.2021.1892956

By:

Eleazu, Kate;
Maduabuchi Aja, Patrick;
Eleazu, Chinedum Ogbonnaya

Publication type:

Article