Works matching IS 00912700 AND DT 2018 AND VI 58

Results: 204

Issue Information.

Published in:: Journal of Clinical Pharmacology, 2018, v. 58, n. 12, p. 1527, doi. 10.1002/jcph.1342
Publication type:: Article

Clinical Pharmacokinetic and Pharmacodynamic Overview of Nilotinib, a Selective Tyrosine Kinase Inhibitor.

Published in:

Journal of Clinical Pharmacology, 2018, v. 58, n. 12, p. 1533, doi. 10.1002/jcph.1312

By:

Tian, Xianbin;
Zhang, Hefei;
Heimbach, Tycho;
He, Handan;
Buchbinder, Aby;
Aghoghovbia, Mary;
Hourcade‐Potelleret, Florence

Publication type:

Article

Population Pharmacokinetics of Lopinavir/Ritonavir: Changes Across Formulations and Human Development From Infancy Through Adulthood.

Published in:

Journal of Clinical Pharmacology, 2018, v. 58, n. 12, p. 1604, doi. 10.1002/jcph.1293

By:

Yang, Jincheng;
Nikanjam, Mina;
Best, Brookie M.;
Pinto, Jorge;
Chadwick, Ellen G.;
Daar, Eric S.;
Havens, Peter L.;
Rakhmanina, Natella;
Capparelli, Edmund V.

Publication type:

Article

Pharmacokinetics of Enoxaparin After Renal Transplantation in Pediatric Patients.

Published in:

Journal of Clinical Pharmacology, 2018, v. 58, n. 12, p. 1597, doi. 10.1002/jcph.1289

By:

Damamme, Alice;
Urien, Saïk;
Borgel, Delphine;
Lasne, Dominique;
Krug, Pauline;
Krid, Saoussen;
Charbit, Marina;
Salomon, Rémi;
Treluyer, Jean‐Marc;
Boyer, Olivia

Publication type:

Article

An Integrated Population Pharmacokinetic Analysis to Characterize Levonorgestrel Pharmacokinetics After Different Administration Routes.

Published in:

Journal of Clinical Pharmacology, 2018, v. 58, n. 12, p. 1639, doi. 10.1002/jcph.1288

By:

Reinecke, Isabel;
Hofmann, Birte;
Mesic, Emir;
Drenth, Henk‐Jan;
Garmann, Dirk

Publication type:

Article

Pharmacokinetics and Pharmacodynamics of Anacetrapib in Black and White Healthy Subjects.

Published in:

Journal of Clinical Pharmacology, 2018, v. 58, n. 12, p. 1578, doi. 10.1002/jcph.1287

By:

Krishna, Rajesh;
Gheyas, Ferdous;
Corr, Christy;
Cote, Josee;
Liu, Yang;
Wagner, John;
Gutstein, David E.

Publication type:

Article

Effect of Hepatic Impairment on the Pharmacokinetics of Alectinib.

Published in:

Journal of Clinical Pharmacology, 2018, v. 58, n. 12, p. 1618, doi. 10.1002/jcph.1286

By:

Morcos, Peter N.;
Cleary, Yumi;
Sturm‐Pellanda, Carolina;
Guerini, Elena;
Abt, Markus;
Donzelli, Massimiliano;
Vazvaei, Faye;
Balas, Bogdana;
Parrott, Neil;
Yu, Li

Publication type:

Article

FDA Public Meeting Report on "Drug Interactions With Hormonal Contraceptives: Public Health and Drug Development Implications".

Published in:

Journal of Clinical Pharmacology, 2018, v. 58, n. 12, p. 1655, doi. 10.1002/jcph.1285

By:

Akbar, Mohammad;
Berry‐Bibee, Erin;
Blithe, Diana L.;
Day, Ruth S.;
Edelman, Alison;
Höchel, Joachim;
Jamshidi, Roxanne;
Kim, Myong‐Jin;
Li, Li;
Purohit, Vivek S.;
Turpin, Jim A.;
Scott, Pamela E.;
Strauss, David G.;
Sun, Haiying;
Tepper, Naomi K.;
Zhang, Lei;
Yu, Chongwoo

Publication type:

Article

Pharmacokinetic and Pharmacodynamic Evaluation of Intravenous Levetiracetam in Children With Epilepsy.

Published in:

Journal of Clinical Pharmacology, 2018, v. 58, n. 12, p. 1586, doi. 10.1002/jcph.1282

By:

Kim, Min‐Jee;
Yum, Mi‐Sun;
Yeh, Hye‐Ryun;
Ko, Tae‐Sung;
Lim, Hyeong‐Seok

Publication type:

Article

Safety, Pharmacokinetics, and Pharmacodynamics of Multiple Rising Doses of BI 655064, an Antagonistic Anti‐CD40 Antibody, in Healthy Subjects: A Potential Novel Treatment for Autoimmune Diseases.

Published in:

Journal of Clinical Pharmacology, 2018, v. 58, n. 12, p. 1566, doi. 10.1002/jcph.1278

By:

Schwabe, Christian;
Rosenstock, Bernd;
Doan, Thi;
Hamilton, Paul;
Dunbar, P. Rod;
Eleftheraki, Anastasia G.;
Joseph, David;
Hilbert, James;
Schoelch, Corinna;
Padula, Steven J.;
Steffgen, Jürgen

Publication type:

Article

Population Pharmacokinetic/Pharmacodynamic Analyses of Avatrombopag in Patients With Chronic Liver Disease and Optimal Dose Adjustment Guide With Concomitantly Administered CYP3A and CYP2C9 Inhibitors.

Published in:

Journal of Clinical Pharmacology, 2018, v. 58, n. 12, p. 1629, doi. 10.1002/jcph.1267

By:

Nomoto, Maiko;
Ferry, Jim;
Hussein, Ziad

Publication type:

Article

Effect of ABCC2 and ABCG2 Gene Polymorphisms and CSF‐to‐Serum Albumin Ratio on Ceftriaxone Plasma and Cerebrospinal Fluid Concentrations.

Published in:

Journal of Clinical Pharmacology, 2018, v. 58, n. 12, p. 1550, doi. 10.1002/jcph.1266

By:

Allegra, Sarah;
Cardellino, Chiara Simona;
Fatiguso, Giovanna;
Cusato, Jessica;
Nicolò, Amedeo;
Avataneo, Valeria;
Bonora, Stefano;
D'Avolio, Antonio;
Di Perri, Giovanni;
Calcagno, Andrea

Publication type:

Article

A Pharmacokinetic and Pharmacogenetic Analysis of Osteosarcoma Patients Treated With High‐Dose Methotrexate: Data From the OS2006/Sarcoma‐09 Trial.

Published in:

Journal of Clinical Pharmacology, 2018, v. 58, n. 12, p. 1541, doi. 10.1002/jcph.1252

By:

Lui, Gabrielle;
Treluyer, Jean‐Marc;
Fresneau, Brice;
Piperno‐Neumann, Sophie;
Gaspar, Nathalie;
Corradini, Nadège;
Gentet, Jean‐Claude;
Marec Berard, Perrine;
Laurence, Valérie;
Schneider, Pascale;
Entz‐Werle, Natacha;
Pacquement, Hélène;
Millot, Frédéric;
Taque, Sophie;
Freycon, Claire;
Lervat, Cyril;
Deley, Marie Cécile;
Mahier Ait Oukhatar, Céline;
Brugieres, Laurence;
Teuff, Gwénaël

Publication type:

Article

A Phase I, Single‐Ascending‐Dose Study in Healthy Subjects to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of DS‐2969b, a Novel GyrB Inhibitor.

Published in:

Journal of Clinical Pharmacology, 2018, v. 58, n. 12, p. 1557, doi. 10.1002/jcph.1151

By:

Dennie, Justin;
Vandell, Alexander G.;
Inoue, Satoshi;
Gajee, Roohi;
Pav, Joseph;
Zhang, George;
Zamora, Cynthia;
Masuda, Nobuhisa;
Uchiyama, Minoru;
Yamada, Makiko;
Senaldi, Giorgio

Publication type:

Article

Issue Information.

Published in:: 2018
Publication type:: Table of Contents

Codeine‐Induced Sensory Neuropathy, Autonomic Dysfunction, and Myopathy.

Published in:

2018

By:

Malek, Elia Gebran;
Salameh, Johnny S.

Publication type:

Letter to the Editor

Population Pharmacokinetic Analysis for Daclatasvir and Asunaprevir in Japanese Subjects With Chronic Hepatitis C Virus Infection.

Published in:

Journal of Clinical Pharmacology, 2018, v. 58, n. 11, p. 1468, doi. 10.1002/jcph.1274

By:

Osawa, Mayu;
Ueno, Takayo;
Ishikawa, Hiroki;
Imai, Yasuhiko;
Garimella, Tushar

Publication type:

Article

Exposure‐Response Modeling Analyses for Sirukumab, a Human Monoclonal Antibody Targeting Interleukin 6, in Patients With Moderately to Severely Active Rheumatoid Arthritis.

Published in:

Journal of Clinical Pharmacology, 2018, v. 58, n. 11, p. 1501, doi. 10.1002/jcph.1272

By:

Xu, Yan;
Hu, Chuanpu;
Zhuang, Yanli;
Hsu, Benjamin;
Xu, Zhenhua;
Sharma, Amarnath;
Zhou, Honghui

Publication type:

Article

An Open‐Label Discontinuation Trial of Long‐Term, Off‐Label Antipsychotic Medication in People With Intellectual Disability: Determinants of Success and Failure.

Published in:

Journal of Clinical Pharmacology, 2018, v. 58, n. 11, p. 1418, doi. 10.1002/jcph.1271

By:

de Kuijper, Gerda M.;
Hoekstra, Pieter J.

Publication type:

Article

Pharmacology of Antiretrovirals in the Female Genital Tract for HIV Prevention.

Published in:

Journal of Clinical Pharmacology, 2018, v. 58, n. 11, p. 1381, doi. 10.1002/jcph.1270

By:

Nicol, Melanie R.;
Corbino, Joseph A.;
Cottrell, Mackenzie L.

Publication type:

Article

Exposure‐Response Modeling to Characterize the Relationship Between Ixekizumab Serum Drug Concentrations and Efficacy Responses at Week 12 in Patients With Moderate to Severe Plaque Psoriasis.

Published in:

Journal of Clinical Pharmacology, 2018, v. 58, n. 11, p. 1489, doi. 10.1002/jcph.1268

By:

Chigutsa, Emmanuel;
Velez de Mendizabal, Nieves;
Chua, Laiyi;
Heathman, Michael;
Friedrich, Stuart;
Jackson, Kimberley;
Reich, Kristian

Publication type:

Article

Calcineurin Inhibitor and Nonsteroidal Anti‐inflammatory Drug Interaction: Implications of Changes in Renal Function Associated With Concurrent Use.

Published in:

Journal of Clinical Pharmacology, 2018, v. 58, n. 11, p. 1443, doi. 10.1002/jcph.1264

By:

Delzer, Luke M.;
Golightly, Larry K.;
Kiser, Tyree H.;
Biggins, Scott W.;
Lewis, Victor J.;
Kim, Ike I.

Publication type:

Article

The Pharmacology, Pharmacokinetics, Efficacy, and Adverse Events Associated With Kava.

Published in:

Journal of Clinical Pharmacology, 2018, v. 58, n. 11, p. 1396, doi. 10.1002/jcph.1263

By:

White, C. Michael

Publication type:

Article

Exposure‐Response (Efficacy) Analysis of Daclatasvir and Asunaprevir in Japanese Patients With Hepatitis C Virus Infection.

Published in:

Journal of Clinical Pharmacology, 2018, v. 58, n. 11, p. 1479, doi. 10.1002/jcph.1262

By:

Ueno, Takayo;
Osawa, Mayu;
Imai, Yasuhiko;
Ishikawa, Hiroki;
Garimella, Tushar

Publication type:

Article

Effect of OATP1B1/1B3 Inhibitor GDC‐0810 on the Pharmacokinetics of Pravastatin and Coproporphyrin I/III in Healthy Female Subjects.

Published in:

Journal of Clinical Pharmacology, 2018, v. 58, n. 11, p. 1427, doi. 10.1002/jcph.1261

By:

Liu, Lichuan;
Cheeti, Sravanthi;
Yoshida, Kenta;
Choo, Edna;
Chen, Eugene;
Chen, Buyun;
Gates, Mary;
Singel, Stina;
Morley, Roland;
Ware, Joseph;
Sahasranaman, Srikumar

Publication type:

Article

Persistence of a Posaconazole‐Mediated Drug‐Drug Interaction With Ranolazine After Cessation of Posaconazole Administration: Impact of Obesity and Implications for Patient Safety.

Published in:

Journal of Clinical Pharmacology, 2018, v. 58, n. 11, p. 1436, doi. 10.1002/jcph.1257

By:

Chow, Christina R.;
Harmatz, Jerold S.;
Ryan, Michael J.;
Greenblatt, David J.

Publication type:

Article

An Evaluation of Efficacy and Safety of Commonly Prescribed Drugs and Effect of These Drugs on Quality of Sleep in Patients Suffering From Zoster‐Associated Pain.

Published in:

Journal of Clinical Pharmacology, 2018, v. 58, n. 11, p. 1406, doi. 10.1002/jcph.1255

By:

Nayak, Mithilesh K.;
Kapadia, Jigar D.;
Desai, Chetna K.;
Desai, Mira K.;
Shah, Bela J.

Publication type:

Article

Population Pharmacokinetic Analysis of Fluticasone Furoate/Umeclidinium/Vilanterol via a Single Inhaler in Patients with COPD.

Published in:

Journal of Clinical Pharmacology, 2018, v. 58, n. 11, p. 1461, doi. 10.1002/jcph.1253

By:

Mehta, Rashmi;
Pefani, Eleni;
Beerahee, Misba;
Brealey, Noushin;
Barnacle, Helen;
Birk, Ruby;
Zhu, Chang‐Qing;
Lipson, David A.

Publication type:

Article

A Randomized, Single‐Center, Double‐Blind, Placebo‐Controlled Multiple‐Dose Phase 1 Study to Evaluate the Safety, Pharmacokinetics, and Pharmacodynamics of Imarikiren in Healthy Adult Nonelderly and Elderly Male Subjects.

Published in:

Journal of Clinical Pharmacology, 2018, v. 58, n. 11, p. 1516, doi. 10.1002/jcph.1142

By:

Matsuno, Kumi;
Tanaka, Shingo;
Hashimoto, Takamasa;
Nakamichi, Hiroyuki;
Kagawa, Tomoya;
Koumura, Emiko

Publication type:

Article

Population Pharmacokinetic Modeling With Enterohepatic Circulation for AZD3241 in Healthy Subjects and Patients With Multiple System Atrophy.

Published in:

Journal of Clinical Pharmacology, 2018, v. 58, n. 11, p. 1452, doi. 10.1002/jcph.1134

By:

Tong, Xiao;
Zhou, Diansong;
Savage, Alicia;
Mullen, Jamie A.;
Li, Yan;
Taylor, Wendy;
Li, Jianguo;
Al‐Huniti, Nidal;
Xu, Hongmei

Publication type:

Article

Issue Information.

Published in:: Journal of Clinical Pharmacology, 2018, v. 58, p. S1, doi. 10.1002/jcph.1322
Publication type:: Article

Developmental Pharmacotherapy: The Interface Between Ontogeny and Drug Effect.

Published in:

Journal of Clinical Pharmacology, 2018, v. 58, p. S7, doi. 10.1002/jcph.1317

By:

Reed, Michael D.;
van den Anker, John

Publication type:

Article

Pharmacometric Modeling and Simulation Is Essential to Pediatric Clinical Pharmacology.

Published in:

Journal of Clinical Pharmacology, 2018, v. 58, p. S73, doi. 10.1002/jcph.1316

By:

Neely, Michael;
Bayard, David;
Desai, Amit;
Kovanda, Laura;
Edginton, Andrea

Publication type:

Article

Developmental Changes in Pharmacokinetics and Pharmacodynamics.

Published in:

Journal of Clinical Pharmacology, 2018, v. 58, p. S10, doi. 10.1002/jcph.1284

By:

van den Anker, John;
Reed, Michael D.;
Allegaert, Karel;
Kearns, Gregory L.

Publication type:

Article

Identifying the “Blip on the Radar Screen”: Leveraging Big Data in Defining Drug Safety and Efficacy in Pediatric Practice.

Published in:

Journal of Clinical Pharmacology, 2018, v. 58, p. S86, doi. 10.1002/jcph.1141

By:

Christensen, Michael L.;
Davis, Robert L.

Publication type:

Article

Vaccine Update: Recent Progress With Novel Vaccines, and New Approaches to Safety Monitoring and Vaccine Shortage.

Published in:

Journal of Clinical Pharmacology, 2018, v. 58, p. S123, doi. 10.1002/jcph.1140

By:

Ndaya‐Oloo, Paul;
Pitisuttithum, Punnee;
Tornieporth, Nadia G.;
Desgrandchamps, Daniel;
Munoz, Flor M.;
Kochhar, Sonali;
Buttery, Jim;
Bauwens, Jorgen;
Bonhoeffer, Jan

Publication type:

Article

Analgesics and Sedatives in Critically Ill Newborns and Infants: The Impact on Long‐Term Neurodevelopment.

Published in:

Journal of Clinical Pharmacology, 2018, v. 58, p. S140, doi. 10.1002/jcph.1139

By:

Schiller, R. M.;
Allegaert, K.;
Hunfeld, Maayke;
van den Bosch, G. E.;
van den Anker, John;
Tibboel, D.

Publication type:

Article

Drug Formulations: Standards and Novel Strategies for Drug Administration in Pediatrics.

Published in:

Journal of Clinical Pharmacology, 2018, v. 58, p. S26, doi. 10.1002/jcph.1138

By:

Thabet, Yasmin;
Klingmann, Viviane;
Breitkreutz, Jörg

Publication type:

Article

Optimizing Antibiotic Drug Therapy in Pediatrics: Current State and Future Needs.

Published in:

Journal of Clinical Pharmacology, 2018, v. 58, p. S108, doi. 10.1002/jcph.1128

By:

Le, Jennifer;
Bradley, John S.

Publication type:

Article

Probiotics in Disease Prevention and Treatment.

Published in:

Journal of Clinical Pharmacology, 2018, v. 58, p. S164, doi. 10.1002/jcph.1121

By:

Liu, Yuying;
Tran, Dat Q.;
Rhoads, J. Marc

Publication type:

Article

Adverse Drug Reactions Across the Age Continuum: Epidemiology, Diagnostic Challenges, Prevention, and Treatments.

Published in:

Journal of Clinical Pharmacology, 2018, v. 58, p. S36, doi. 10.1002/jcph.1115

By:

Rieder, Michael

Publication type:

Article

Opioids in Breast Milk: Pharmacokinetic Principles and Clinical Implications.

Published in:

Journal of Clinical Pharmacology, 2018, v. 58, p. S151, doi. 10.1002/jcph.1113

By:

Ito, Shinya

Publication type:

Article

Pediatric Obesity: Influence on Drug Dosing and Therapeutics.

Published in:

Journal of Clinical Pharmacology, 2018, v. 58, p. S94, doi. 10.1002/jcph.1092

By:

Ameer, Barbara;
Weintraub, Michael A.

Publication type:

Article

The Path to Perfect Pediatric Posology — Drug Development in Pediatrics.

Published in:

Journal of Clinical Pharmacology, 2018, v. 58, p. S48, doi. 10.1002/jcph.1081

By:

Korth‐Bradley, Joan M.

Publication type:

Article

Innovative Study Designs Optimizing Clinical Pharmacology Research in Infants and Children.

Published in:

Journal of Clinical Pharmacology, 2018, v. 58, p. S58, doi. 10.1002/jcph.1053

By:

Balevic, Stephen J.;
Cohen‐Wolkowiez, Michael

Publication type:

Article

Issue Information.

Published in:: Journal of Clinical Pharmacology, 2018, v. 58, n. 10, p. 1233, doi. 10.1002/jcph.1319
Publication type:: Article

Drug Interaction Involving Direct or Indirect Cytokine Modulation Should Be Investigated in Select Circumstances.

Published in:

Journal of Clinical Pharmacology, 2018, v. 58, n. 10, p. 1373, doi. 10.1002/jcph.1303

By:

Coutant, David E.;
Hall, Stephen D.

Publication type:

Article

Are Clinical Therapeutic Protein‐Drug Interaction Studies Needed When Disease Modification Is Driving the Potential Interaction?

Published in:

Journal of Clinical Pharmacology, 2018, v. 58, n. 10, p. 1371, doi. 10.1002/jcph.1290

By:

Pang, Yinuo;
Rosebraugh, Matthew R.;
Freise, Kevin J.;
Parikh, Apurvasena;
Mohamed, Mohamed‐Eslam F.

Publication type:

Article

A Change in Posture Significantly Affects Plasma Concentrations of Large Molecules Such as IgG Antibodies.

Published in:

Journal of Clinical Pharmacology, 2018, v. 58, n. 10, p. 1340, doi. 10.1002/jcph.1150

By:

van Iersel, Mattheus (Thijs);
Velinova, Maria I.

Publication type:

Article

Population Pharmacokinetics and Pharmacodynamics of Oral Propranolol in Pediatric Patients With Infantile Hemangioma.

Published in:

Journal of Clinical Pharmacology, 2018, v. 58, n. 10, p. 1361, doi. 10.1002/jcph.1149

By:

Takechi, Tomoki;
Kumokawa, Tadao;
Kato, Rumiko;
Higuchi, Takeshi;
Kaneko, Tsuyoshi;
Ieiri, Ichiro

Publication type:

Article