Works matching IS 00912700 AND DT 2017 AND VI 57

Results: 199

A Cross-Study Analysis Evaluating the Effects of Food on the Pharmacokinetics of Rivaroxaban in Clinical Studies.

Published in:

Journal of Clinical Pharmacology, 2017, v. 57, n. 12, p. 1607, doi. 10.1002/jcph.958

By:

Zhang, Liping;
Peters, Gary;
Haskell, Lloyd;
Patel, Purve;
Nandy, Partha;
Moore, Kenneth Todd

Publication type:

Article

Pharmacokinetics, Safety, and Tolerability of Glecaprevir and Pibrentasvir in Healthy White, Chinese, and Japanese Adult Subjects.

Published in:

Journal of Clinical Pharmacology, 2017, v. 57, n. 12, p. 1616, doi. 10.1002/jcph.959

By:

Lin, Chih‐Wei;
Dutta, Sandeep;
Ding, Bifeng;
Wang, Tianli;
Zadeikis, Neddie;
Asatryan, Armen;
Kort, Jens;
Campbell, Andrew;
Podsadecki, Thomas;
Liu, Wei

Publication type:

Article

Bioequivalence of Intravenous and Oral Rolapitant: Results From a Randomized, Open-Label Pivotal Study.

Published in:

Journal of Clinical Pharmacology, 2017, v. 57, n. 12, p. 1600, doi. 10.1002/jcph.966

By:

Wang, Xiaodong;
Zhang, Zhi‐Yi;
Powers, Daniel;
Wang, Jing;
Lu, Sharon;
Arora, Sujata;
Hughes, Lorraine;
Christensen, Jennifer;
Kansra, Vikram

Publication type:

Article

Model-Based Assessment Using Conventional Bioequivalence Limits to Ensure Safety and Efficacy of Rivaroxaban in Patients Undergoing Hip or Knee Replacement.

Published in:

Journal of Clinical Pharmacology, 2017, v. 57, n. 12, p. 1591, doi. 10.1002/jcph.930

By:

González‐Sales, Mario;
Fang, Lanyan;
Kim, Myong‐Jin;
Zhao, Liang

Publication type:

Article

A Dual-Administration Microtracer Technique to Characterize the Absorption, Distribution, Metabolism, and Excretion of [<sup>14</sup>C]Seletalisib (UCB5857) in Healthy Subjects.

Published in:

Journal of Clinical Pharmacology, 2017, v. 57, n. 12, p. 1582, doi. 10.1002/jcph.954

By:

Helmer, Eric;
Nicolas, Jean‐Marie;
Long, Jeff;
Roffel, Ad F.;
Jones, Emma;
Chanteux, Hugues;
Diaz, Nieves;
Garratt, Holly;
Bosje, Tjerk

Publication type:

Article

Population Pharmacokinetic Analysis of Vaginally and Intravenously Administered Oxytocin in Postmenopausal Women.

Published in:

Journal of Clinical Pharmacology, 2017, v. 57, n. 12, p. 1573, doi. 10.1002/jcph.961

By:

Nielsen, Elisabet I.;
Al‐Saqi, Shahla H.;
Jonasson, Aino F.;
Uvnäs‐Moberg, Kerstin

Publication type:

Article

Dosage Optimization of Nemolizumab Using Population Pharmacokinetic and Pharmacokinetic-Pharmacodynamic Modeling and Simulation.

Published in:

Journal of Clinical Pharmacology, 2017, v. 57, n. 12, p. 1564, doi. 10.1002/jcph.969

By:

Saito, Tomohisa;
Iida, Satofumi;
Terao, Kimio;
Kumagai, Yuji

Publication type:

Article

Population Pharmacokinetics of Imatinib in Nigerians With Chronic Myeloid Leukemia: Clinical Implications for Dosing and Resistance.

Published in:

Journal of Clinical Pharmacology, 2017, v. 57, n. 12, p. 1554, doi. 10.1002/jcph.953

By:

Adeagbo, Babatunde Ayodeji;
Olugbade, Tiwalade Adewale;
Durosinmi, Muheez Alani;
Bolarinwa, Rahman Ayodele;
Ogungbenro, Kayode;
Bolaji, Oluseye Oladotun

Publication type:

Article

Population Pharmacokinetic and Exposure-Response Analysis of Weekly Teriparatide in Osteoporosis Patients.

Published in:

Journal of Clinical Pharmacology, 2017, v. 57, n. 12, p. 1545, doi. 10.1002/jcph.949

By:

Ose, Atsushi;
Serada, Masashi;
Yamashita, Keiko;
Tsurui, Kazuyuki;
Tanigawara, Yusuke

Publication type:

Article

An Exploratory Study in Healthy Male Subjects of the Mechanism of Mirabegron-Induced Cardiovascular Effects.

Published in:

Journal of Clinical Pharmacology, 2017, v. 57, n. 12, p. 1534, doi. 10.1002/jcph.952

By:

Gelderen, Marcel;
Stölzel, Matthias;
Meijer, John;
Kerbusch, Virginie;
Collins, Christiane;
Korstanje, Cees

Publication type:

Article

Exposure-Response Analysis of Nivolumab in Patients With Previously Treated or Untreated Advanced Melanoma.

Published in:

Journal of Clinical Pharmacology, 2017, v. 57, n. 12, p. 1527, doi. 10.1002/jcph.962

By:

Bajaj, Gaurav;
Gupta, Manish;
Feng, Yan;
Statkevich, Paul;
Roy, Amit

Publication type:

Article

Effect of Agomelatine and Fluoxetine on HAM-D Score, Serum Brain-Derived Neurotrophic Factor, and Tumor Necrosis Factor-α Level in Patients With Major Depressive Disorder With Severe Depression.

Published in:

Journal of Clinical Pharmacology, 2017, v. 57, n. 12, p. 1519, doi. 10.1002/jcph.963

By:

Gupta, Keshav;
Gupta, Rachna;
Bhatia, M.S.;
Tripathi, A.K.;
Gupta, Lalit K.

Publication type:

Article

A Pathogenic Mechanism Potentially Operative in Multiple Progressive Diseases and Its Therapeutic Implications.

Published in:

Journal of Clinical Pharmacology, 2017, v. 57, n. 12, p. 1507, doi. 10.1002/jcph.997

By:

Re, Richard N.

Publication type:

Article

BACE1 Inhibitor Lanabecestat (AZD3293) in a Phase 1 Study of Healthy Japanese Subjects: Pharmacokinetics and Effects on Plasma and Cerebrospinal Fluid Aβ Peptides.

Published in:

Journal of Clinical Pharmacology, 2017, v. 57, n. 11, p. 1460, doi. 10.1002/jcph.950

By:

Sakamoto, Kei;
Matsuki, Shunji;
Matsuguma, Kyoko;
Yoshihara, Tatsuya;
Uchida, Naoki;
Azuma, Fumihiko;
Russell, Muir;
Hughes, Glen;
Haeberlein, Samantha Budd;
Alexander, Robert C.;
Eketjäll, Susanna;
Kugler, Alan R.

Publication type:

Article

Utilization of the Bridging Strategy for the Development of New Drugs in Oncology to Avoid Drug Lag.

Published in:

Journal of Clinical Pharmacology, 2017, v. 57, n. 11, p. 1479, doi. 10.1002/jcph.951

By:

Kogure, Seiji;
Koyama, Nobuyuki;
Hidaka, Shinji

Publication type:

Article

The Effect of Renal Impairment on the Pharmacokinetics and Pharmacodynamics of Ertugliflozin in Subjects With Type 2 Diabetes Mellitus.

Published in:

Journal of Clinical Pharmacology, 2017, v. 57, n. 11, p. 1432, doi. 10.1002/jcph.955

By:

Sahasrabudhe, V.;
Terra, S. G.;
Hickman, A.;
Saur, D.;
Shi, H.;
O'Gorman, M.;
Zhou, Z.;
Cutler, D. L.

Publication type:

Article

Notable Drug-Drug Interaction Between Etizolam and Itraconazole in Poor Metabolizers of Cytochrome P450 2C19.

Published in:

Journal of Clinical Pharmacology, 2017, v. 57, n. 11, p. 1491, doi. 10.1002/jcph.956

By:

Yamamoto, Takehito;
Furihata, Kenichi;
Hisaka, Akihiro;
Moritoyo, Takashi;
Ogoe, Kazuaki;
Kusayama, Shizuko;
Motohashi, Keiju;
Mori, Akiko;
Iwatsubo, Takeshi;
Suzuki, Hiroshi

Publication type:

Article

Issue Information.

Published in:: Journal of Clinical Pharmacology, 2017, v. 57, n. 11, p. 1363, doi. 10.1002/jcph.1033
Publication type:: Article

Addressing Antiretroviral Therapy-Associated Drug-Drug Interactions in Patients Requiring Treatment for Opportunistic Infections in Low-Income and Resource-Limited Settings.

Published in:

Journal of Clinical Pharmacology, 2017, v. 57, n. 11, p. 1387, doi. 10.1002/jcph.978

By:

Chastain, Daniel B.;
Franco‐Paredes, Carlos;
Stover, Kayla R.

Publication type:

Article

Optimization of Maternal Magnesium Sulfate Administration for Fetal Neuroprotection: Application of a Prospectively Constructed Pharmacokinetic Model to the BEAM Cohort.

Published in:

Journal of Clinical Pharmacology, 2017, v. 57, n. 11, p. 1419, doi. 10.1002/jcph.941

By:

Brookfield, Kathleen F.;
Elkomy, Mohammed;
Su, Felice;
Drover, David R.;
Carvalho, Brendan

Publication type:

Article

Safety and Pharmacokinetics of Bendamustine Rapid-Infusion Formulation.

Published in:

Journal of Clinical Pharmacology, 2017, v. 57, n. 11, p. 1400, doi. 10.1002/jcph.942

By:

Cheung, Eric M.;
Edenfield, William J.;
Mattar, Bassam;
Anthony, Stephen P.;
Mutch, Peter J.;
Chanas, Brian;
Smith, Mark;
Hepner, Adrian

Publication type:

Article

Lucerastat, an Iminosugar for Substrate Reduction Therapy: Pharmacokinetics, Tolerability, and Safety in Subjects With Mild, Moderate, and Severe Renal Function Impairment.

Published in:

Journal of Clinical Pharmacology, 2017, v. 57, n. 11, p. 1425, doi. 10.1002/jcph.944

By:

Guérard, Nicolas;
Zwingelstein, Christian;
Dingemanse, Jasper

Publication type:

Article

Approach to Fingolimod-Induced Lymphopenia in Multiple Sclerosis Patients: Do We Have a Roadmap?

Published in:

Journal of Clinical Pharmacology, 2017, v. 57, n. 11, p. 1415, doi. 10.1002/jcph.945

By:

Avasarala, Jagannadha;
Jain, Sandip;
Urrea‐Mendoza, Enrique

Publication type:

Article

Pharmacokinetic Characterization and Dose Selection of a Novel Sumatriptan Nasal Spray Formulation, DFN-02.

Published in:

Journal of Clinical Pharmacology, 2017, v. 57, n. 11, p. 1472, doi. 10.1002/jcph.946

By:

Pal, Arindam;
Gautam, Anirudh;
Munjal, Sagar

Publication type:

Article

Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of the Novel CRTH2 Antagonist BI 1021958 at Single Oral Doses in Healthy Men and Multiple Oral Doses in Men and Women With Well-Controlled Asthma.

Published in:

Journal of Clinical Pharmacology, 2017, v. 57, n. 11, p. 1444, doi. 10.1002/jcph.947

By:

Fowler, Andy;
Koenen, Rüdiger;
Hilbert, James;
Blatchford, Jon;
Kappeler, Dominik;
Benediktus, Ewald;
Wood, Chester;
Gupta, Abhya

Publication type:

Article

Effect of Hepatic Impairment on Eluxadoline Pharmacokinetics.

Published in:

Journal of Clinical Pharmacology, 2017, v. 57, n. 11, p. 1454, doi. 10.1002/jcph.964

By:

Marbury, Thomas C.;
Berg, Jolene Kay;
Dove, Leonard S.;
Covington, Paul S.

Publication type:

Article

A Review of Moxifloxacin for the Treatment of Drug-Susceptible Tuberculosis.

Published in:

Journal of Clinical Pharmacology, 2017, v. 57, n. 11, p. 1369, doi. 10.1002/jcph.968

By:

Naidoo, Anushka;
Naidoo, Kogieleum;
McIlleron, Helen;
Essack, Sabiha;
Padayatchi, Nesri

Publication type:

Article

An Open-Label Dose-Finding Study of Allopurinol to Target Defined Reduction in Urate Levels in Hemodialysis Patients.

Published in:

Journal of Clinical Pharmacology, 2017, v. 57, n. 11, p. 1409, doi. 10.1002/jcph.939

By:

Rutherford, Elaine;
Stewart, Graham;
Houston, J. Graeme;
Jardine, Alan G.;
Mark, Patrick B.;
Struthers, Allan D.

Publication type:

Article

Issue Information.

Published in:: Journal of Clinical Pharmacology, 2017, v. 57, p. S1, doi. 10.1002/jcph.1020
Publication type:: Article

RNA Therapeutics in Oncology: Advances, Challenges, and Future Directions.

Published in:

Journal of Clinical Pharmacology, 2017, v. 57, p. S43, doi. 10.1002/jcph.957

By:

MacLeod, A. Robert;
Crooke, Stanley T.

Publication type:

Article

Clinical Pharmacology Tools and Evaluations to Facilitate Comprehensive Dose Finding in Oncology: A Continuous Risk-Benefit Approach.

Published in:

Journal of Clinical Pharmacology, 2017, v. 57, p. S105, doi. 10.1002/jcph.908

By:

Bullock, Julie M.;
Lin, Tiffany;
Bilic, Sanela

Publication type:

Article

The Role of Clinical Pharmacology in Oncology Dose Selection: Advances and Opportunities in Personalized Medicine.

Published in:

Journal of Clinical Pharmacology, 2017, v. 57, p. S99, doi. 10.1002/jcph.922

By:

Shord, Stacy S.

Publication type:

Article

Standing in the Shifting Sands of Molecular Targeting and Precision Medicine Is the Oasis of 21st-Century Oncology Therapeutics.

Published in:

Journal of Clinical Pharmacology, 2017, v. 57, p. S7, doi. 10.1002/jcph.1011

By:

Lee, Lucy;
Lewis, Lionel D.

Publication type:

Article

Clinical Pharmacology Considerations for the Development of Immune Checkpoint Inhibitors.

Published in:

Journal of Clinical Pharmacology, 2017, v. 57, p. S26, doi. 10.1002/jcph.990

By:

Sheng, Jennifer;
Srivastava, Shivani;
Sanghavi, Kinjal;
Lu, Zheng;
Schmidt, Brian J.;
Bello, Akintunde;
Gupta, Manish

Publication type:

Article

Pharmacogenomics Implementation at the National Institutes of Health Clinical Center.

Published in:

Journal of Clinical Pharmacology, 2017, v. 57, p. S67, doi. 10.1002/jcph.993

By:

Sissung, Tristan M.;
McKeeby, Jon W.;
Patel, Jharana;
Lertora, Juan J.;
Kumar, Parag;
Flegel, Willy A.;
Adams, Sharon D.;
Eckes, Ellen J.;
Mickey, Frank;
Plona, Teri M.;
Mellott, Stephanie D.;
Baugher, Ryan N.;
Wu, Xiaolin;
Soppet, Daniel R.;
Barcus, Mary E.;
Datta, Vivekananda;
Pike, Kristen M.;
DiPatrizio, Gary;
Figg, William D.;
Goldspiel, Barry R.

Publication type:

Article

How Often Are Drugs Made Available Under the Food and Drug Administration's Expanded Access Process Approved?

Published in:

Journal of Clinical Pharmacology, 2017, v. 57, p. S136, doi. 10.1002/jcph.960

By:

McKee, Amy E.;
Markon, André O.;
Chan‐Tack, Kirk M.;
Lurie, Peter

Publication type:

Article

Bridging Adult Experience to Pediatrics in Oncology Drug Development.

Published in:

Journal of Clinical Pharmacology, 2017, v. 57, p. S129, doi. 10.1002/jcph.910

By:

Leong, Ruby;
Zhao, Hong;
Reaman, Gregory;
Liu, Qi;
Wang, Yaning;
Stewart, Clinton F.;
Burckart, Gilbert

Publication type:

Article

Dose Finding Versus Speed in Seamless Immuno-Oncology Drug Development.

Published in:

Journal of Clinical Pharmacology, 2017, v. 57, p. S143, doi. 10.1002/jcph.1001

By:

Mayawala, Kapil;
Tse, Archie;
Rubin, Eric H.;
Jain, Lokesh;
Alwis, Dinesh P.

Publication type:

Article

Antibody-Drug Conjugates as Cancer Therapeutics: Past, Present, and Future.

Published in:

Journal of Clinical Pharmacology, 2017, v. 57, p. S11, doi. 10.1002/jcph.981

By:

Vezina, Heather E.;
Cotreau, Monette;
Han, Tae H.;
Gupta, Manish

Publication type:

Article

Critical Considerations in Anticancer Drug Development and Dosing Strategies: The Past, Present, and Future.

Published in:

Journal of Clinical Pharmacology, 2017, v. 57, p. S116, doi. 10.1002/jcph.983

By:

Mould, Diane R.;
Hutson, Paul R.

Publication type:

Article

Somatic Mutation Analysis of Human Cancers: Challenges in Clinical Practice.

Published in:

Journal of Clinical Pharmacology, 2017, v. 57, p. S60, doi. 10.1002/jcph.934

By:

Tsongalis, Gregory J.;
Coleman, William B.

Publication type:

Article

Pharmacokinetic-Guided Dosing of New Oral Cancer Agents.

Published in:

Journal of Clinical Pharmacology, 2017, v. 57, p. S78, doi. 10.1002/jcph.937

By:

Lucas, Catherine J.;
Martin, Jennifer H.

Publication type:

Article

Reply to Letter: The Use of IC50 for Potency and MTD as Objective in Study BIA 10-2474, by Mattheus van Iersel, MD.

Published in:

Journal of Clinical Pharmacology, 2017, v. 57, n. 10, p. 1359, doi. 10.1002/jcph.1000

By:

Chaikin, Philip

Publication type:

Article

In Memoriam: Gerhard Levy, PharmD.

Published in:

Journal of Clinical Pharmacology, 2017, v. 57, n. 10, p. 1239, doi. 10.1002/jcph.1013

By:

Bertino, Joseph S.

Publication type:

Article

Issue Information.

Published in:: Journal of Clinical Pharmacology, 2017, v. 57, n. 10, p. 1233, doi. 10.1002/jcph.1019
Publication type:: Article

Pharmacokinetic Study of Intravenous Acetaminophen Administered to Critically Ill Multiple-Trauma Patients at the Usual Dosage and a New Proposal for Administration.

Published in:

Journal of Clinical Pharmacology, 2017, v. 57, n. 10, p. 1345, doi. 10.1002/jcph.903

By:

Fuster ‐ Lluch, Oscar;
Zapater ‐ Hernández, Pedro;
Gerónimo ‐ Pardo, Manuel

Publication type:

Article

The Utility of a Population Approach in Drug-Drug Interaction Assessments: A Simulation Evaluation.

Published in:

Journal of Clinical Pharmacology, 2017, v. 57, n. 10, p. 1268, doi. 10.1002/jcph.921

By:

Wang, Diane D.;
Yu, Yanke;
Kassir, Nastya;
Zhu, Min;
Hanley, William D.;
Earp, Justin C.;
Chow, Andrew T.;
Gupta, Manish;
Hu, Chuanpu

Publication type:

Article

Population Pharmacokinetics and Exposure Response Assessment of CC-292, a Potent BTK Inhibitor, in Patients With Chronic Lymphocytic Leukemia.

Published in:

Journal of Clinical Pharmacology, 2017, v. 57, n. 10, p. 1279, doi. 10.1002/jcph.923

By:

Li, Yan;
Ramírez ‐ Valle, Francisco;
Xue, Yongjun;
Ventura, Judith I.;
Gouedard, Olivier;
Mei, Jay;
Takeshita, Kenichi;
Palmisano, Maria;
Zhou, Simon

Publication type:

Article

Lack of Effect of Rivipansel on QTc Interval in Healthy Adult African American Male Subjects.

Published in:

Journal of Clinical Pharmacology, 2017, v. 57, n. 10, p. 1315, doi. 10.1002/jcph.924

By:

Tammara, Brinda K.;
Plotka, Anna;
Shafer, Frank E.;
Readett, David R. J.;
Riley, Steve;
Korth ‐ Bradley, Joan M.

Publication type:

Article

Psychomotor Tremor and Proprioceptive Control Problems in Current and Former Stimulant Drug Users: An Accelerometer Study of Heavy Users of Amphetamine, MDMA, and Other Recreational Stimulants.

Published in:

Journal of Clinical Pharmacology, 2017, v. 57, n. 10, p. 1330, doi. 10.1002/jcph.925

By:

Downey, Luke A.;
Tysse, Brenda;
Ford, Talitha C.;
Samuels, Angela C.;
Wilson, Rory P.;
Parrott, Andrew C.

Publication type:

Article