Works matching IS 00912700 AND DT 2016 AND VI 56

Results: 208

Pharmacokinetics and Pharmacodynamics of Canakinumab in Patients With Systemic Juvenile Idiopathic Arthritis.

Published in:

Journal of Clinical Pharmacology, 2016, v. 56, n. 12, p. 1516, doi. 10.1002/jcph.754

By:

Sun, Haiying;
Van, Linh M.;
Floch, David;
Jiang, Xuemin;
Klein, Ulf R.;
Abrams, Ken;
Sunkara, Gangadhar

Publication type:

Article

Artemisia Extract Improves Insulin Sensitivity in Women With Gestational Diabetes Mellitus by Up-Regulating Adiponectin.

Published in:

Journal of Clinical Pharmacology, 2016, v. 56, n. 12, p. 1550, doi. 10.1002/jcph.755

By:

Sun, Xia;
Sun, Hong;
Zhang, Jing;
Ji, Xianghong

Publication type:

Article

Long-Term Effect of Rifampicin-Based Anti-TB Regimen Coadministration on the Pharmacokinetic Parameters of Efavirenz and 8-Hydroxy-Efavirenz in Ethiopian Patients.

Published in:

Journal of Clinical Pharmacology, 2016, v. 56, n. 12, p. 1538, doi. 10.1002/jcph.756

By:

Habtewold, Abiy;
Aklillu, Eleni;
Makonnen, Eyasu;
Amogne, Wondwossen;
Yimer, Getnet;
Aderaye, Getachew;
Bertilsson, Leif;
Owen, Joel S.;
Burhenne, Jürgen

Publication type:

Article

Sex Differences in mRNA Expression of Reduced Folate Carrier-1, Folypolyformyl Glutamate Synthase, and γ-Glutamyl Hydrolase in a Healthy Japanese Population.

Published in:

Journal of Clinical Pharmacology, 2016, v. 56, n. 12, p. 1563, doi. 10.1002/jcph.760

By:

Hashiguchi, Masayuki;
Tanaka, Takanori;
Shimizu, Mikiko;
Tsuru, Tomomi;
Chiyoda, Takeshi;
Miyawaki, Kumika;
Irie, Shin;
Takeuchi, Osamu;
Hakamata, Jun;
Mochizuki, Mayumi

Publication type:

Article

Use of an Oral Busulfan Test Dose in Patients Undergoing Hematopoietic Stem Cell Transplantation Treated With or Without Fludarabine.

Published in:

Journal of Clinical Pharmacology, 2016, v. 56, n. 12, p. 1555, doi. 10.1002/jcph.758

By:

Castro, Francine Attié;
Simões, Belinda Pinto;
Godoy, Ana Leonor Pardo Campos;
Bertagnoli Trigo, Fernanda Manuela;
Coelho, Eduardo Barbosa;
Lanchote, Vera Lucia

Publication type:

Article

Evaluation of Rifampin's Transporter Inhibitory and CYP3A Inductive Effects on the Pharmacokinetics of Venetoclax, a BCL-2 Inhibitor: Results of a Single- and Multiple-Dose Study.

Published in:

Journal of Clinical Pharmacology, 2016, v. 56, n. 11, p. 1335, doi. 10.1002/jcph.730

By:

Agarwal, Suresh K.;
Hu, Beibei;
Chien, David;
Wong, Shekman L.;
Salem, Ahmed Hamed

Publication type:

Article

Bridging the Academia/Industry Chasm: Proposed Solutions.

Published in:

Journal of Clinical Pharmacology, 2016, v. 56, n. 12, p. 1457, doi. 10.1002/jcph.762

By:

Beninger, Paul;
Boumil, Marcia;
Salem, Deeb;
Getz, Kenneth;
Klapholz, Henry;
Curfman, Gregory D.;
Jotwani, Rohan;
Berman, Harris

Publication type:

Article

Pharmacokinetics and Tolerability of a Dual Variable Domain Immunoglobulin ABT-981 Against IL-1α and IL-1β in Healthy Subjects and Patients With Osteoarthritis of the Knee.

Published in:

Journal of Clinical Pharmacology, 2016, v. 56, n. 12, p. 1582, doi. 10.1002/jcph.764

By:

Kosloski, Matthew P.;
Goss, Sandra;
Wang, Susanne X.;
Liu, Jia;
Loebbert, Ralf;
Medema, Jeroen K.;
Liu, Wei;
Dutta, Sandeep

Publication type:

Article

Precision Oncology Medicine: The Clinical Relevance of Patient-Specific Biomarkers Used to Optimize Cancer Treatment.

Published in:

Journal of Clinical Pharmacology, 2016, v. 56, n. 12, p. 1484, doi. 10.1002/jcph.765

By:

Schmidt, Keith T.;
Chau, Cindy H.;
Price, Douglas K.;
Figg, William D.

Publication type:

Article

The Metabolism of Clopidogrel: CYP2C19 Is a Minor Pathway.

Published in:

Journal of Clinical Pharmacology, 2016, v. 56, n. 12, p. 1474, doi. 10.1002/jcph.769

By:

Ford, Neville F.

Publication type:

Article

Brivaracetam Population Pharmacokinetics and Exposure-Response Modeling in Adult Subjects With Partial-Onset Seizures.

Published in:

Journal of Clinical Pharmacology, 2016, v. 56, n. 12, p. 1591, doi. 10.1002/jcph.761

By:

Schoemaker, Rik;
Wade, Janet R.;
Stockis, Armel

Publication type:

Article

Extended-Release Once-Daily Formulation of Tofacitinib: Evaluation of Pharmacokinetics Compared With Immediate-Release Tofacitinib and Impact of Food.

Published in:

Journal of Clinical Pharmacology, 2016, v. 56, n. 11, p. 1362, doi. 10.1002/jcph.734

By:

Lamba, Manisha;
Wang, Rong;
Fletcher, Tracey;
Alvey, Christine;
Kushner, Joseph;
Stock, Thomas C.

Publication type:

Article

Multigene and Drug Interaction Approach for Tamoxifen Metabolite Patterns Reveals Possible Involvement of CYP2C9, CYP2C19, and ABCB1.

Published in:

Journal of Clinical Pharmacology, 2016, v. 56, n. 12, p. 1570, doi. 10.1002/jcph.771

By:

Powers, Jennifer L.;
Buys, Saundra S.;
Fletcher, Deborah;
Melis, Roberta;
Johnson‐Davis, Kamisha L.;
Lyon, Elaine;
Malmberg, Elisabeth M.;
McMillin, Gwendolyn A.

Publication type:

Article

Proton Pump Inhibitors Are Not Associated With Acute Kidney Injury in Critical Illness.

Published in:

Journal of Clinical Pharmacology, 2016, v. 56, n. 12, p. 1500, doi. 10.1002/jcph.805

By:

Lee, Joon;
Mark, Roger G.;
Celi, Leo Anthony;
Danziger, John

Publication type:

Article

Dosage Adjustments Related to Young or Old Age and Organ Impairment.

Published in:

Journal of Clinical Pharmacology, 2016, v. 56, n. 12, p. 1461, doi. 10.1002/jcph.816

By:

Burris, James F.;
Tortorici, Michael A.;
Mandic, Maja;
Neely, Michael;
Reed, Michael D.

Publication type:

Article

Issue Information.

Published in:: Journal of Clinical Pharmacology, 2016, v. 56, n. 12, p. 1451, doi. 10.1002/jcph.845
Publication type:: Article

Adverse Drug Reactions in Patients Receiving Systemic Antifungal Therapy at a High-Complexity Hospital.

Published in:

Journal of Clinical Pharmacology, 2016, v. 56, n. 12, p. 1507, doi. 10.1002/jcph.772

By:

Souza, Maria Clara Padovani;
Santos, Andrezza Gouvêa dos;
Reis, Adriano Max Moreira

Publication type:

Article

Pharmacokinetics and Pharmacodynamics of Omarigliptin, a Once-Weekly Dipeptidyl Peptidase-4 (DPP-4) Inhibitor, After Single and Multiple Doses in Healthy Subjects.

Published in:

Journal of Clinical Pharmacology, 2016, v. 56, n. 12, p. 1528, doi. 10.1002/jcph.773

By:

Krishna, Rajesh;
Addy, Carol;
Tatosian, Daniel;
Glasgow, Xiaoli S.;
Gendrano III, Isaias Noel;
Robberechts, Martine;
Haazen, Wouter;
Hoon, J.N.;
Depré, Marleen;
Martucci, Ashley;
Peng, Joanna Z.;
Johnson‐Levonas, Amy O.;
Wagner, John A.;
Stoch, S. Aubrey

Publication type:

Article

Potential Underprediction of Warfarin Drug Interaction From Conventional Interaction Studies and Risk Mitigation: A Case Study With Epacadostat, an IDO1 Inhibitor.

Published in:

Journal of Clinical Pharmacology, 2016, v. 56, n. 11, p. 1344, doi. 10.1002/jcph.737

By:

Shi, Jack G.;
Chen, Xuejun;
Punwani, Naresh G.;
Williams, William V.;
Yeleswaram, Swamy

Publication type:

Article

Compliance, Persistence, and Preferences Regarding Osteoporosis Treatment During Active Therapy or Drug Holiday.

Published in:

Journal of Clinical Pharmacology, 2016, v. 56, n. 11, p. 1416, doi. 10.1002/jcph.738

By:

Eliasaf, Alona;
Amitai, Alina;
Maram Edry, Mira;
Yosselson Superstine, Shimona;
Rotman Pikielny, Pnina

Publication type:

Article

Exposure-Response Analysis of Sonidegib (LDE225), an Oral Inhibitor of the Hedgehog Signaling Pathway, for Effectiveness and Safety in Patients With Advanced Solid Tumors.

Published in:

Journal of Clinical Pharmacology, 2016, v. 56, n. 11, p. 1406, doi. 10.1002/jcph.749

By:

Zhou, Jocelyn;
Quinlan, Michelle;
Hurh, Eunju;
Sellami, Dalila

Publication type:

Article

The Effect of Age on the Pharmacokinetics of Udenafil in Healthy Subjects.

Published in:

Journal of Clinical Pharmacology, 2016, v. 56, n. 11, p. 1372, doi. 10.1002/jcph.739

By:

Choi, Hyang‐Ki;
Jung, Jin Ah;
Shon, Jihong;
Bahng, Mi Young;
Cho, Doo‐Yeoun;
Yeo, Chang Woo;
Kim, Eun‐Young;
Shin, Jae‐Gook

Publication type:

Article

Mephedrone and 3,4-Methylenedioxypyrovalerone (MDPV): Synthetic Cathinones With Serious Health Implications.

Published in:

Journal of Clinical Pharmacology, 2016, v. 56, n. 11, p. 1319, doi. 10.1002/jcph.742

By:

White, C. Michael

Publication type:

Article

Exposure Matching for Extrapolation of Efficacy in Pediatric Drug Development.

Published in:

Journal of Clinical Pharmacology, 2016, v. 56, n. 11, p. 1326, doi. 10.1002/jcph.744

By:

Mulugeta, Yeruk;
Barrett, Jeffrey S.;
Nelson, Robert;
Eshete, Abel Tilahun;
Mushtaq, Alvina;
Yao, Lynne;
Glasgow, Nicole;
Mulberg, Andrew E.;
Gonzalez, Daniel;
Green, Dionna;
Florian, Jeffry;
Krudys, Kevin;
Seo, Shirley;
Kim, Insook;
Chilukuri, Dakshina;
Burckart, Gilbert J.

Publication type:

Article

Pharmacokinetic Variability of Mycophenolic Acid in Pediatric and Adult Patients With Hematopoietic Stem Cell Transplantation.

Published in:

Journal of Clinical Pharmacology, 2016, v. 56, n. 11, p. 1378, doi. 10.1002/jcph.745

By:

Zhang, Daping;
Renbarger, Jamie L.;
Chow, Diana S‐L.

Publication type:

Article

Temozolomide-Associated Liver Fibrosis.

Published in:

Journal of Clinical Pharmacology, 2016, v. 56, n. 11, p. 1448, doi. 10.1002/jcph.753

By:

Parakh, Sagun;
Hamid, Anis;
Cher, Lawrence;
Gan, Hui K.

Publication type:

Article

Effect of Low- and High-Fat Meals on the Pharmacokinetics of Venetoclax, a Selective First-in-Class BCL-2 Inhibitor.

Published in:

Journal of Clinical Pharmacology, 2016, v. 56, n. 11, p. 1355, doi. 10.1002/jcph.741

By:

Salem, Ahmed Hamed;
Agarwal, Suresh K.;
Dunbar, Martin;
Nuthalapati, Silpa;
Chien, David;
Freise, Kevin J.;
Wong, Shekman L.

Publication type:

Article

Role of Tiotropium in Reducing Exacerbations of Chronic Obstructive Pulmonary Disease When Combined With Long-Acting β<sub>2</sub>-Agonists and Inhaled Corticosteroids: The OUTPUL Study.

Published in:

Journal of Clinical Pharmacology, 2016, v. 56, n. 11, p. 1423, doi. 10.1002/jcph.750

By:

Ferroni, Eliana;
Belleudi, Valeria;
Cascini, Silvia;
Di Martino, Mirko;
Kirchmayer, Ursula;
Pistelli, Riccardo;
Patorno, Elisabetta;
Formoso, Giulio;
Fusco, Danilo;
Perucci, Carlo A.;
Davoli, Marina;
Agabiti, Nera

Publication type:

Article

Integrating Dynamic Positron Emission Tomography and Conventional Pharmacokinetic Studies to Delineate Plasma and Tumor Pharmacokinetics of FAU, a Prodrug Bioactivated by Thymidylate Synthase.

Published in:

Journal of Clinical Pharmacology, 2016, v. 56, n. 11, p. 1433, doi. 10.1002/jcph.751

By:

Li, Jing;
Kim, Seongho;
Shields, Anthony F.;
Douglas, Kirk A.;
McHugh, Christopher I.;
Lawhorn‐Crews, Jawana M.;
Wu, Jianmei;
Mangner, Thomas J.;
LoRusso, Patricia M.

Publication type:

Article

Pharmacokinetic Properties of Nintedanib in Healthy Volunteers and Patients With Advanced Cancer.

Published in:

Journal of Clinical Pharmacology, 2016, v. 56, n. 11, p. 1387, doi. 10.1002/jcph.752

By:

Dallinger, Claudia;
Trommeshauser, Dirk;
Marzin, Kristell;
Liesener, Andre;
Kaiser, Rolf;
Stopfer, Peter

Publication type:

Article

Pharmacokinetics and Pharmacokinetic/Pharmacodynamic Relationships of Etravirine in HIV-1-Infected, Treatment-Experienced Children and Adolescents in PIANO.

Published in:

Journal of Clinical Pharmacology, 2016, v. 56, n. 11, p. 1395, doi. 10.1002/jcph.746

By:

Kakuda, Thomas N.;
Brochot, Anne;
Green, Bruce;
Nijs, Steven;
Vis, Peter;
Opsomer, Magda;
Tomaka, Frank L.;
Hoetelmans, Richard M. W.

Publication type:

Article

Issue Information.

Published in:: Journal of Clinical Pharmacology, 2016, v. 56, n. 11, p. 1313, doi. 10.1002/jcph.836
Publication type:: Article

A Randomized Trial Evaluating Various Administration Routes of Natalizumab in Multiple Sclerosis.

Published in:

Journal of Clinical Pharmacology, 2016, v. 56, n. 10, p. 1254, doi. 10.1002/jcph.707

By:

Plavina, Tatiana;
Fox, Edward J.;
Lucas, Nisha;
Muralidharan, Kumar Kandadi;
Mikol, Daniel

Publication type:

Article

Ketoconazole-Associated Liver Injury in Drug-Drug Interaction Studies in Healthy Volunteers.

Published in:

Journal of Clinical Pharmacology, 2016, v. 56, n. 10, p. 1196, doi. 10.1002/jcph.711

By:

Banankhah, Peymaan S.;
Garnick, Kyle A.;
Greenblatt, David J.

Publication type:

Article

The Pharmacokinetics of Potassium in Humans Is Unusual.

Published in:

Journal of Clinical Pharmacology, 2016, v. 56, n. 10, p. 1212, doi. 10.1002/jcph.713

By:

Hinderling, Peter H.

Publication type:

Article

Dose-Dependent Flux of Buprenorphine Following Transdermal Administration in Healthy Subjects.

Published in:

Journal of Clinical Pharmacology, 2016, v. 56, n. 10, p. 1263, doi. 10.1002/jcph.718

By:

Wang, Yi;
Cipriano, Alessandra;
Munera, Catherine;
Harris, Stephen C.

Publication type:

Article

The Effect of a High-Fat Meal on the Pharmacokinetics of Ixazomib, an Oral Proteasome Inhibitor, in Patients With Advanced Solid Tumors or Lymphoma.

Published in:

Journal of Clinical Pharmacology, 2016, v. 56, n. 10, p. 1288, doi. 10.1002/jcph.719

By:

Gupta, Neeraj;
Hanley, Michael J.;
Venkatakrishnan, Karthik;
Wang, Bingxia;
Sharma, Sunil;
Bessudo, Alberto;
Hui, Ai‐Min;
Nemunaitis, John

Publication type:

Article

A Critical Evaluation of Pharmacogenetic Information in Package Inserts for Selected Drugs Marketed in India and Its Comparison With US FDA-Approved Package Inserts.

Published in:

Journal of Clinical Pharmacology, 2016, v. 56, n. 10, p. 1232, doi. 10.1002/jcph.720

By:

Pai, Sarayu Arvind;
Kshirsagar, Nilima

Publication type:

Article

Response Surface Analysis and Nonlinear Optimization Algorithm for Maximization of Clinical Drug Performance: Application to Extended-Release and Long-Acting Injectable Paliperidone.

Published in:

Journal of Clinical Pharmacology, 2016, v. 56, n. 10, p. 1296, doi. 10.1002/jcph.724

By:

Gomeni, Roberto;
Bressolle‐Gomeni, Françoise;
Fava, Maurizio

Publication type:

Article

A Clinical Study Evaluating the Effects of Fluvastatin on Serum Osteoprotegerin Levels in Rheumatoid Arthritis Patients.

Published in:

Journal of Clinical Pharmacology, 2016, v. 56, n. 10, p. 1272, doi. 10.1002/jcph.725

By:

Hegazy, Sahar Kamal;
El‐Ghany El‐Sayed, Salwa El‐Morsy Abd;
El‐Hefnawy, Marwa El‐Saeed

Publication type:

Article

Use of Monte Carlo Simulations to Determine Optimal Carbapenem Dosing in Critically Ill Patients Receiving Prolonged Intermittent Renal Replacement Therapy.

Published in:

Journal of Clinical Pharmacology, 2016, v. 56, n. 10, p. 1277, doi. 10.1002/jcph.727

By:

Lewis, Susan J.;
Kays, Michael B.;
Mueller, Bruce A.

Publication type:

Article

The Use of Dried Blood Spots for Pharmacokinetic Monitoring of Vemurafenib Treatment in Melanoma Patients.

Published in:

Journal of Clinical Pharmacology, 2016, v. 56, n. 10, p. 1307, doi. 10.1002/jcph.728

By:

Nijenhuis, Cynthia M.;
Huitema, Alwin D.R.;
Marchetti, Serena;
Blank, Christian;
Haanen, John B.A.G.;
Thienen, Johannes V.;
Rosing, Hilde;
Schellens, Jan H.M.;
Beijnen, Jos H.

Publication type:

Article

Pharmacokinetics and Pharmacodynamics for Medical Students: A Proposed Course Outline.

Published in:

Journal of Clinical Pharmacology, 2016, v. 56, n. 10, p. 1180, doi. 10.1002/jcph.732

By:

Greenblatt, David J.;
Abourjaily, Paul N.

Publication type:

Article

How Informative Are Drug-Drug Interactions of Gene-Drug Interactions?

Published in:

Journal of Clinical Pharmacology, 2016, v. 56, n. 10, p. 1221, doi. 10.1002/jcph.743

By:

Lagishetty, Chakradhar V.;
Deng, Jiexin;
Lesko, Lawrence J.;
Rogers, Hobart;
Pacanowski, Michael;
Schmidt, Stephan

Publication type:

Article

How to Fix the Dangerous Lack of Clinical Pharmacology Education in the Medical Profession: The Generation of Core Entrustable Professional Activities in Clinical Pharmacology for Entering Residency.

Published in:

Journal of Clinical Pharmacology, 2016, v. 56, n. 10, p. 1177, doi. 10.1002/jcph.748

By:

Donnenberg, Vera S.;
Burris, James F.;
Wiernik, Peter H.;
Cohen, Lawrence J.;
Korth‐Bradley, Joan M.

Publication type:

Article

Pharmacokinetic Properties and Human Use Characteristics of an FDA-Approved Intranasal Naloxone Product for the Treatment of Opioid Overdose.

Published in:

Journal of Clinical Pharmacology, 2016, v. 56, n. 10, p. 1243, doi. 10.1002/jcph.759

By:

Krieter, Philip;
Chiang, Nora;
Gyaw, Shwe;
Skolnick, Phil;
Crystal, Roger;
Keegan, Fintan;
Aker, Julie;
Beck, Melissa;
Harris, Jennifer

Publication type:

Article

No Increased Risk of Ketoconazole Toxicity in Drug-Drug Interaction Studies.

Published in:

Journal of Clinical Pharmacology, 2016, v. 56, n. 10, p. 1203, doi. 10.1002/jcph.795

By:

Outeiro, Noémi;
Hohmann, Nicolas;
Mikus, Gerd

Publication type:

Article

Issue Information.

Published in:: Journal of Clinical Pharmacology, 2016, v. 56, n. 10, p. 1171, doi. 10.1002/jcph.824
Publication type:: Article

Use of Antipsychotics for the Treatment of Behavioral Symptoms of Dementia.

Published in:

Journal of Clinical Pharmacology, 2016, v. 56, n. 9, p. 1048, doi. 10.1002/jcph.731

By:

Greenblatt, H. Karl;
Greenblatt, David J.

Publication type:

Article

Issue Information.

Published in:: Journal of Clinical Pharmacology, 2016, v. 56, n. 9, p. 1039, doi. 10.1002/jcph.802
Publication type:: Article