Works matching IS 00778923 AND DT 2000 AND VI 920 AND IP 1

Results: 48

Progress in Hereditary Tauopathies: A Mutation in the Tau Gene (G389R) Causes a Pick Disease-like Syndrome.

Published in:

Annals of the New York Academy of Sciences, 2000, v. 920, n. 1, p. 52, doi. 10.1111/j.1749-6632.2000.tb06905.x

By:

GHETTI, BERNARDINO;
MURRELL, JILL R.;
ZOLO, PAOLO;
SPILLANTINI, MARIA GRAZIA;
GOEDERT, MICHEL

Publication type:

Article

Presenilin-1: A Component of Synaptic and Endothelial Adherens Junctions.

Published in:

Annals of the New York Academy of Sciences, 2000, v. 920, n. 1, p. 209, doi. 10.1111/j.1749-6632.2000.tb06924.x

By:

GEORGAKOPOULOS, ANASTASIOS;
MARAMBAUD, PHILIPPE;
FRIEDRICH, VICTOR L.;
SHIOI, JUNICHI;
EFTHIMIOPOULOS, SPIROS;
ROBAKIS, NIKOLAOS K.

Publication type:

Article

The Clinical Spectrum of Guam ALS and Parkinson-Dementia Complex: 1997-1999.

Published in:

Annals of the New York Academy of Sciences, 2000, v. 920, n. 1, p. 120, doi. 10.1111/j.1749-6632.2000.tb06913.x

By:

GALASKO, DOUGLAS;
SALMON, DAVID;
CRAIG, ULLA-KATRINA;
WIEDERHOLT, WIGBERT

Publication type:

Article

Modulation of Aβ Deposition in APP Transgenic Mice by an Apolipoprotein E Null Background.

Published in:

Annals of the New York Academy of Sciences, 2000, v. 920, n. 1, p. 171, doi. 10.1111/j.1749-6632.2000.tb06919.x

By:

IRIZARRY, M. C.;
REBECK, G. W.;
CHEUNG, B.;
BALES, K.;
PAUL, S. M;
HOLZMAN, D.;
HYMAN, B. T.

Publication type:

Article

Treatment with the Selective Muscarinic Agonist Talsaclidine Decreases Cerebrospinal Fluid Levels of Total Amyloid β-Peptide in Patients with Alzheimer's Disease.

Published in:

Annals of the New York Academy of Sciences, 2000, v. 920, n. 1, p. 285, doi. 10.1111/j.1749-6632.2000.tb06937.x

By:

HOCK, C.;
MADDALENA, A.;
HEUSER, I.;
NABER, D.;
OERTEL, W.;
KAMMER, H.;
WIENRICH, M.;
RASCHIG, A.;
DENG, M.;
GROWDON, J. H.;
NITSCH, R. M.

Publication type:

Article

Inhibition of the Neuronal Insulin Receptor An in Vivo Model for Sporadic Alzheimer Disease?

Published in:

Annals of the New York Academy of Sciences, 2000, v. 920, n. 1, p. 256, doi. 10.1111/j.1749-6632.2000.tb06932.x

By:

HOYER, SIEGFRIED;
LEE, SAE KYUNG;
LÖFFLER, THOMAS;
SCHLIEBS, REINHARD

Publication type:

Article

Prevention and Reduction of AD-type Pathology in PDAPP Mice Immunized with Aβ<sub>1-42</sub>.

Published in:

Annals of the New York Academy of Sciences, 2000, v. 920, n. 1, p. 274, doi. 10.1111/j.1749-6632.2000.tb06936.x

By:

GAMES, DORA;
BARD, FREDERIQUE;
GRAJEDA, HENRY;
GUIDO, TERRY;
KHAN, KAREN;
SORIANO, FERDIE;
VASQUEZ, NICKI;
WEHNER, NANCY;
JOHNSON-WOOD, KELLY;
YEDNOCK, TED;
SEUBERT, PETER;
SCHENK, DALE

Publication type:

Article

α1-Antichymotrypsin Inhibits Aβ Degradation in Vitro and in Vivo.

Published in:

Annals of the New York Academy of Sciences, 2000, v. 920, n. 1, p. 245, doi. 10.1111/j.1749-6632.2000.tb06930.x

By:

ABRAHAM, CARMELA R.;
McGRAW, WALKER T.;
SLOT, FRANCHOT;
YAMIN, RINA

Publication type:

Article

Activated Mitogenic Signaling Induces a Process of Dedifferentiation in Alzheimer's Disease That Eventually Results in Cell Death.

Published in:

Annals of the New York Academy of Sciences, 2000, v. 920, n. 1, p. 249, doi. 10.1111/j.1749-6632.2000.tb06931.x

By:

ARENDT, THOMAS;
HOLZER, MAX;
STÖBE, ANDREA;
GÄRTNER, ULRICH;
LÜTH, HANS-JOACHIM;
BRÜCKNER, MARTINA K.;
UEBERHAM, UWE

Publication type:

Article

Toward the Characterization and Identification of γ-Secretases Using Transition-state Analogue Inhibitors.

Published in:

Annals of the New York Academy of Sciences, 2000, v. 920, n. 1, p. 197, doi. 10.1111/j.1749-6632.2000.tb06922.x

By:

MOORE, CHAD L.;
DIEHL, THEKLA S.;
SELKOE, DENNIS J.;
WOLFE, MICHAEL S.

Publication type:

Article

The Value of Transgenic Models for the Study of Neurodegenerative Diseases.

Published in:

Annals of the New York Academy of Sciences, 2000, v. 920, n. 1, p. 179, doi. 10.1111/j.1749-6632.2000.tb06920.x

By:

PRICE, DONALD L.;
WONG, PHILIP C.;
MARKOWSKA, ALICJA L.;
LEE, MICHAEL K.;
THINAKAREN, GOPAL;
CLEVELAND, DONALD W.;
SISODIA, SANGRAM S.;
BORCHELT, DAVID R.

Publication type:

Article

GSK3β Forms a Tetrameric Complex with Endogenous PS1-CTF/NTF and β-Catenin: Effects of the D257/D385A and FAD-linked Mutations.

Published in:

Annals of the New York Academy of Sciences, 2000, v. 920, n. 1, p. 227, doi. 10.1111/j.1749-6632.2000.tb06927.x

By:

TESCO, G.;
TANZI, R. E.

Publication type:

Article

Molecular Genetics of Chromosome 17 Tauopathies.

Published in:

Annals of the New York Academy of Sciences, 2000, v. 920, n. 1, p. 63, doi. 10.1111/j.1749-6632.2000.tb06906.x

By:

HUTTON, MICHAEL

Publication type:

Article

Tau Gene Mutations in Frontotemporal Dementia and Parkinsonism Linked to Chromosome 17 (FTDP-17): Their Relevance for Understanding the Neurogenerative Process.

Published in:

Annals of the New York Academy of Sciences, 2000, v. 920, n. 1, p. 74, doi. 10.1111/j.1749-6632.2000.tb06907.x

By:

GOEDERT, MICHEL;
GHETTI, BERNARDINO;
SPILLANTINI, MARIA GRAZIA

Publication type:

Article

The α-Synucleinopathies: Parkinson's Disease, Dementia with Lewy Bodies, and Multiple System Atrophy.

Published in:

Annals of the New York Academy of Sciences, 2000, v. 920, n. 1, p. 16, doi. 10.1111/j.1749-6632.2000.tb06900.x

By:

SPILLANTINI, MARIA GRAZIA;
GOEDERT, MICHEL

Publication type:

Article

Cholinesterase Inhibitors Stabilize Alzheimer's Disease.

Published in:

Annals of the New York Academy of Sciences, 2000, v. 920, n. 1, p. 321, doi. 10.1111/j.1749-6632.2000.tb06942.x

By:

GIACOBINI, EZIO

Publication type:

Article

Cytidine (5′) Diphosphocholine Modulates Dopamine K<sup>+</sup>-evoked Release in Striatum Measured by Microdialysis.

Published in:

Annals of the New York Academy of Sciences, 2000, v. 920, n. 1, p. 332, doi. 10.1111/j.1749-6632.2000.tb06944.x

By:

AGUT, J.;
ORTIZ, J. A.;
WURTMAN, R. J.

Publication type:

Article

An Empirical Model of γ-Secretase Activity.

Published in:

Annals of the New York Academy of Sciences, 2000, v. 920, n. 1, p. 233, doi. 10.1111/j.1749-6632.2000.tb06928.x

By:

MURPHY, M. P.;
WANG, R.;
FRASER, P. E.;
FAUQ, A.;
GOLDE, T. E.

Publication type:

Article

Clinical Lewy Body Syndromes.

Published in:

Annals of the New York Academy of Sciences, 2000, v. 920, n. 1, p. 1, doi. 10.1111/j.1749-6632.2000.tb06898.x

By:

McKEITH, I. G.

Publication type:

Article

α-Secretase Activity of the Disintegrin Metalloprotease ADAM 10: Influences of Domain Structure.

Published in:

Annals of the New York Academy of Sciences, 2000, v. 920, n. 1, p. 215, doi. 10.1111/j.1749-6632.2000.tb06925.x

By:

FAHRENHOLZ, FALK;
GILBERT, SANDRA;
KOJRO, ELZBIETA;
LAMMICH, SVEN;
POSTINA, ROLF

Publication type:

Article

Identifying Proteases That Cleave APP.

Published in:

Annals of the New York Academy of Sciences, 2000, v. 920, n. 1, p. 192, doi. 10.1111/j.1749-6632.2000.tb06921.x

By:

CITRON, MARTIN

Publication type:

Article

Pathogenic Mechanisms of Alzheimer's Disease Analyzed in the APP23 Transgenic Mouse Model.

Published in:

Annals of the New York Academy of Sciences, 2000, v. 920, n. 1, p. 134, doi. 10.1111/j.1749-6632.2000.tb06915.x

By:

STURCHLER-PIERRAT, CHRISTINE;
STAUFENBIEL, MATTHIAS

Publication type:

Article

Cytoplasmic Presenilin Aggregates in Proteasome Inhibitor-treated Cells.

Published in:

Annals of the New York Academy of Sciences, 2000, v. 920, n. 1, p. 259, doi. 10.1111/j.1749-6632.2000.tb06933.x

By:

INGANO, L.A. MacKENZIE;
LENTINI, K. M.;
KOVACS, I.;
TANZI, R. E.;
KOVACS, D. M.

Publication type:

Article

Clinical and Neuropathological Correlates of Dementia with Lewy Bodies.

Published in:

Annals of the New York Academy of Sciences, 2000, v. 920, n. 1, p. 9, doi. 10.1111/j.1749-6632.2000.tb06899.x

By:

GÓMEZ-TORTOSA, E.;
IRIZARRY, M. C.;
GÓMEZ-ISLA, T.;
HYMAN, B. T.

Publication type:

Article

Physiology and Pathophysiology of α-Synuclein: Cell Culture and Transgenic Animal Models Based on a Parkinson's Disease-associated Protein.

Published in:

Annals of the New York Academy of Sciences, 2000, v. 920, n. 1, p. 33, doi. 10.1111/j.1749-6632.2000.tb06902.x

By:

KAHLE, PHILIPP J.;
NEUMANN, MANUELA;
OZMEN, LAURENCE;
HAASS, CHRISTIAN

Publication type:

Article

Amyloidogenesis in Familial British Dementia Is Associated with a Genetic Defect on Chromosome 13.

Published in:

Annals of the New York Academy of Sciences, 2000, v. 920, n. 1, p. 84, doi. 10.1111/j.1749-6632.2000.tb06908.x

By:

GHISO, J.;
VIDAL, R.;
ROSTAGNO, A.;
MIRAVALLE, L.;
HOLTON, J. L.;
MEAD, S.;
RÉVÉSZ, T.;
PLANT, G.;
FRANGIONE, B.

Publication type:

Article

Regulation of APP Synthesis and Secretion by Neuroimmunophilin Ligands and Cyclooxygenase Inhibitors.

Published in:

Annals of the New York Academy of Sciences, 2000, v. 920, n. 1, p. 261, doi. 10.1111/j.1749-6632.2000.tb06934.x

By:

LEE, ROBERT K.K.;
WURTMAN, RICHARD J.

Publication type:

Article

In Vivo Analysis of Wild-type and FTDP-17 Tau Transgenic Mice.

Published in:

Annals of the New York Academy of Sciences, 2000, v. 920, n. 1, p. 126, doi. 10.1111/j.1749-6632.2000.tb06914.x

By:

GÖTZ, J.;
BARMETTLER, R.;
FERRARI, A.;
GOEDERT, M.;
PROBST, A.;
NITSCH, R. M.

Publication type:

Article

Prions: Pathogenesis and Reverse Genetics.

Published in:

Annals of the New York Academy of Sciences, 2000, v. 920, n. 1, p. 140, doi. 10.1111/j.1749-6632.2000.tb06916.x

By:

AGUZZI, ADRIANO;
KLEIN, MICHAEL A.;
MONTRASIO, FABIO;
PEKARIK, VLADIMIR;
BRANDNER, SEBASTIAN;
FURUKAWA, HISAKO;
KÄSER, PASCAL;
RÖCKL, CHRISTIANE;
GLATZEL, MARKUS

Publication type:

Article

Nasal Aβ Treatment Induces Anti-Aβ Antibody Production and Decreases Cerebral Amyloid Burden in PD-APP Mice.

Published in:

Annals of the New York Academy of Sciences, 2000, v. 920, n. 1, p. 328, doi. 10.1111/j.1749-6632.2000.tb06943.x

By:

LEMERE, C.A.;
MARON, R.;
SPOONER, E.T.;
GRENFELL, T.J.;
MORI, C.;
DESAI, R.;
HANCOCK, W. W.;
WEINER, H. L.;
SELKOE, D. J.

Publication type:

Article

Coexistent Tau and Amyloid Pathology in Hereditary Frontotemporal Dementia with Tau Mutations.

Published in:

Annals of the New York Academy of Sciences, 2000, v. 920, n. 1, p. 115, doi. 10.1111/j.1749-6632.2000.tb06912.x

By:

ROSSO, S. M.;
KAMPHORST, W.;
RAVID, R.;
SWIETEN, J. C.

Publication type:

Article

Aβ Modulation: The Next Generation of AD Therapeutics.

Published in:

Annals of the New York Academy of Sciences, 2000, v. 920, n. 1, p. 269, doi. 10.1111/j.1749-6632.2000.tb06935.x

By:

FELSENSTEIN, KEVIN M.

Publication type:

Article

High Frequency of Mutations in Four Different Disease Genes in Early-Onset Dementia.

Published in:

Annals of the New York Academy of Sciences, 2000, v. 920, n. 1, p. 100, doi. 10.1111/j.1749-6632.2000.tb06910.x

By:

FINCKH, ULRICH;
MÜLLER-THOMSEN, TOMAS;
MANN, ULRIKE;
EGGERS, CHRISTIAN;
MARKSTEINER, JOSEF;
MEINS, WOLFGANG;
BINETTI, GIULIANO;
ALBERICI, ANTONELLA;
SONDEREGGER, PETER;
HOCK, CHRISTOPH;
NITSCH, ROGER M.;
GAL, ANDREAS

Publication type:

Article

Preface.

Published in:

Annals of the New York Academy of Sciences, 2000, v. 920, n. 1, p. xi, doi. 10.1111/j.1749-6632.2000.tb06897.x

By:

Growdon, John H.;
Wurtman, Richard J.;
Corkin, Suzanne;
Nitsch, Roger M.

Publication type:

Article

Regulation of Gene Expression by Muscarinic Acetylcholine Receptors: A Comprehensive Approach for the Identification of Regulated Genes.

Published in:

Annals of the New York Academy of Sciences, 2000, v. 920, n. 1, p. 305, doi. 10.1111/j.1749-6632.2000.tb06939.x

By:

KAMMER, HEINZ;
MAYHAUS, MANUEL;
ALBRECHT, CLAUDIA;
ANDRESEN, BARBARA;
KLAUDINY, JAROSLAV;
DEMIRALAY, CÜNEYT;
NITSCH, ROGER M.

Publication type:

Article

Cholinergic Modulation of Amyloid Processing and Dementia in Animal Models of Alzheimer's Disease.

Published in:

Annals of the New York Academy of Sciences, 2000, v. 920, n. 1, p. 309, doi. 10.1111/j.1749-6632.2000.tb06940.x

By:

ISACSON, O.;
LIN, L.

Publication type:

Article

Recent Advances in the Understanding of the Processing of APP to Beta Amyloid Peptide.

Published in:

Annals of the New York Academy of Sciences, 2000, v. 920, n. 1, p. 206, doi. 10.1111/j.1749-6632.2000.tb06923.x

By:

SINHA, S.;
ANDERSON, J.;
JOHN, V.;
McCONLOGUE, L.;
BASI, G.;
THORSETT, E.;
SCHENK, D.

Publication type:

Article

Role of Presenilin-1 in Murine Neural Development.

Published in:

Annals of the New York Academy of Sciences, 2000, v. 920, n. 1, p. 165, doi. 10.1111/j.1749-6632.2000.tb06918.x

By:

YANG, XUDONG;
HANDLER, MELISSA;
SHEN, JIE

Publication type:

Article

Pathological Tau Phenotypes: The Weight of Mutations, Polymorphisms, and Differential Neuronal Vulnerabilities.

Published in:

Annals of the New York Academy of Sciences, 2000, v. 920, n. 1, p. 107, doi. 10.1111/j.1749-6632.2000.tb06911.x

By:

MAILLIOT, CHRISTEL;
BUSSIÈRE, THIERRY;
HAMDANE, MALIKA;
SERGEANT, NICOLAS;
CAILLET, MARIE-LAURE;
DELACOURTE, ANDRÉ;
BUÉE, LUC

Publication type:

Article

Presenilin Function in APP Processing.

Published in:

Annals of the New York Academy of Sciences, 2000, v. 920, n. 1, p. 158, doi. 10.1111/j.1749-6632.2000.tb06917.x

By:

ANNAERT, WIM;
CUPERS, PHILIPPE;
SAFTIG, PAUL;
STROOPER, BART

Publication type:

Article

Accelerated Oligomerization by Parkinson's Disease Linked α-Synuclein Mutants.

Published in:

Annals of the New York Academy of Sciences, 2000, v. 920, n. 1, p. 42, doi. 10.1111/j.1749-6632.2000.tb06903.x

By:

CONWAY, K. A.;
LEE, S.-J;
ROCHET, J.-C;
DING, T. T.;
HARPER, J. D.;
WILLIAMSON, R. E.;
LANSBURY, P. T.

Publication type:

Article

Familial British Dementia: Expression and Metabolism of BRI.

Published in:

Annals of the New York Academy of Sciences, 2000, v. 920, n. 1, p. 93, doi. 10.1111/j.1749-6632.2000.tb06909.x

By:

KIM, SEONG-HUN;
WANG, RONG;
GORDON, DAVID J.;
BASS, JOSEPH;
STEINER, DONALD F.;
THINAKARAN, GOPAL;
LYNN, DAVID G.;
MEREDITH, STEPHEN C.;
SISODIA, SANGRAM S.

Publication type:

Article

Classification and Description of Frontotemporal Dementias.

Published in:

Annals of the New York Academy of Sciences, 2000, v. 920, n. 1, p. 46, doi. 10.1111/j.1749-6632.2000.tb06904.x

By:

NEARY, D.;
SNOWDEN, J. S.;
MANN, D. M.A.

Publication type:

Article

Genetics of Parkinson's Disease.

Published in:

Annals of the New York Academy of Sciences, 2000, v. 920, n. 1, p. 28, doi. 10.1111/j.1749-6632.2000.tb06901.x

By:

POLYMEROPOULOS, MIHAEL H.

Publication type:

Article

M1 Muscarinic Agonists as Potential Disease-Modifying Agents in Alzheimer's Disease: Rationale and Perspectives.

Published in:

Annals of the New York Academy of Sciences, 2000, v. 920, n. 1, p. 315, doi. 10.1111/j.1749-6632.2000.tb06941.x

By:

FISHER, A.;
MICHAELSON, D.M.;
BRANDEIS, R.;
HARING, R.;
CHAPMAN, S.;
PITTEL, Z.

Publication type:

Article

Overexpression of Presenilin-2 Enhances Apoptotic Death of Cultured Cortical Neurons.

Published in:

Annals of the New York Academy of Sciences, 2000, v. 920, n. 1, p. 241, doi. 10.1111/j.1749-6632.2000.tb06929.x

By:

ARAKI, W.;
YUASA, K.;
TAKEDA, S.;
SHIROTANI, K.;
TAKAHASHI, K.;
TABIRA, T.

Publication type:

Article

Metal Chelation as a Potential Therapy for Alzheimer's Disease.

Published in:

Annals of the New York Academy of Sciences, 2000, v. 920, n. 1, p. 292, doi. 10.1111/j.1749-6632.2000.tb06938.x

By:

CUAJUNGCO, MATH P.;
FAGÉT, KYLE Y.;
HUANG, XUDONG;
TANZI, RUDOLPH E.;
BUSH, ASHLEY I.

Publication type:

Article

Rapid Notch1 Nuclear Translocation after Ligand Binding Depends on Presenilin-associated γ-Secretase Activity.

Published in:

Annals of the New York Academy of Sciences, 2000, v. 920, n. 1, p. 223, doi. 10.1111/j.1749-6632.2000.tb06926.x

By:

BEREZOVSKA, OKSANA;
JACK, CHRISTINE;
McLEAN, PAMELA;
ASTER, JON C.;
HICKS, CAROL;
XIA, WEIMING;
WOLFE, MICHAEL S.;
WEINMASTER, GERRY;
SELKOE, DENNIS J.;
HYMAN, BRADLEY T.

Publication type:

Article