Works matching IS 00778923 AND DT 1996 AND VI 803 AND IP 1

Results: 39

The Current Status of Irinotecan (CPT-11) in the United States.

Published in:

Annals of the New York Academy of Sciences, 1996, v. 803, n. 1, p. 272, doi. 10.1111/j.1749-6632.1996.tb26397.x

By:

ROTHENBERG, MACE L.

Publication type:

Article

Identification of Topoisomerase I Mutations Affecting Both DNA Cleavage and Interaction with Camptothecina.

Published in:

Annals of the New York Academy of Sciences, 1996, v. 803, n. 1, p. 111, doi. 10.1111/j.1749-6632.1996.tb26381.x

By:

LI, XI-GUANG;
HALUSKA, PAUL;
HSIANG, YAW-HUEI;
BHARTI, AJIT;
KUFE, DONALD W.;
RUBIN, ERIC H.

Publication type:

Article

Trials of 9-Amino-20(S)-Camptothecin in Boston.

Published in:

Annals of the New York Academy of Sciences, 1996, v. 803, n. 1, p. 247, doi. 10.1111/j.1749-6632.1996.tb26394.x

By:

EDER, JOSEPH P.;
RUBIN, ERIC;
STONE, RICHARD;
BRYANT, MARGARET;
XU, GUANXIAN;
SUPKO, JEFFREY;
KINCHLA, NANCY;
LYNCH, THOMAS;
HURWITZ, SELWYN;
RODRIGUEZ, DEE;
SHAPIRO, CHARLES;
TOPPMEYER, DEBORAH;
GROSSBARD, MICHAEL;
VOSBURG, EVAN;
HUBERMAN, MARK;
SCHNIPPER, LOWELL;
SHULMAN, LAWRENCE;
KUFE, DONALD W.

Publication type:

Article

Schedule-dependent Efficacy of Camptothecins in Models of Human Cancera.

Published in:

Annals of the New York Academy of Sciences, 1996, v. 803, n. 1, p. 188, doi. 10.1111/j.1749-6632.1996.tb26388.x

By:

HOUGHTON, PETER J.;
STEWART, CLINTON F.;
ZAMBONI, WILLIAM C.;
THOMPSON, JOYCE;
LUO, XIALOLONG;
DANKS, MARY K.;
HOUGHTON, JANET A.

Publication type:

Article

The Effect of Camptothecin on Topoisomerase I Catalysisa.

Published in:

Annals of the New York Academy of Sciences, 1996, v. 803, n. 1, p. 50, doi. 10.1111/j.1749-6632.1996.tb26376.x

By:

CHRISTIANSEN, KENT;
WESTERGAARD, OLE

Publication type:

Article

Using Yeast to Understand Drugs that Target Topoisomerasesa.

Published in:

Annals of the New York Academy of Sciences, 1996, v. 803, n. 1, p. 32, doi. 10.1111/j.1749-6632.1996.tb26374.x

By:

NITISS, JOHN L.;
ROSE, ANGELA;
SYKES, KARIN C.;
HARRIS, JAMES;
ZHOU, JUNFANG

Publication type:

Article

Chemistry of the Camptothecins in the Bloodstream.

Published in:

Annals of the New York Academy of Sciences, 1996, v. 803, n. 1, p. 29, doi. 10.1111/j.1749-6632.1996.tb26373.x

By:

BURKE, THOMAS G.

Publication type:

Article

Radiation Enhancement by 9-Aminocamptothecin.

Published in:

Annals of the New York Academy of Sciences, 1996, v. 803, n. 1, p. 312, doi. 10.1111/j.1749-6632.1996.tb26403.x

By:

KIRICHENKO, A. V.;
TRAVIS, E. L.;
RICH, T. A.

Publication type:

Article

9-Aminocamptothecin and Beyond.

Published in:

Annals of the New York Academy of Sciences, 1996, v. 803, n. 1, p. 231, doi. 10.1111/j.1749-6632.1996.tb26393.x

By:

POTMESIL, MILAN;
ARBUCK, SUSAN G.;
TAKIMOTO, CHRIS H.;
LIEBES, LEONARD;
HOCHSTER, HOWARD

Publication type:

Article

Topoisomerase I Inhibition by the Camptothecin Analog G1147211C.

Published in:

Annals of the New York Academy of Sciences, 1996, v. 803, n. 1, p. 202, doi. 10.1111/j.1749-6632.1996.tb26389.x

By:

BESTERMAN, JEFFREY M.

Publication type:

Article

Preclinical Antitumor Activity and Pharmacokinetics of Irinotecan (CPT-11) in Tumor-bearing Mice.

Published in:

Annals of the New York Academy of Sciences, 1996, v. 803, n. 1, p. 173, doi. 10.1111/j.1749-6632.1996.tb26386.x

By:

BISSERY, MARIE-CHRISTINE;
VRIGNAUD, PATRICIA;
LAVELLE, FRANCOIS;
CHABOT, GUY G.

Publication type:

Article

CPT-11.

Published in:

Annals of the New York Academy of Sciences, 1996, v. 803, n. 1, p. 282, doi. 10.1111/j.1749-6632.1996.tb26398.x

By:

ARMAND, J. P.;
TERRET, C.;
COUTEAU, C.;
RIXE, O.

Publication type:

Article

Camptothecin and Its Analogs.

Published in:

Annals of the New York Academy of Sciences, 1996, v. 803, n. 1, p. 213, doi. 10.1111/j.1749-6632.1996.tb26391.x

By:

MUGGIA, FRANCO M.;
DIMERY, ISAIAH;
ARBUCK, SUSAN G.

Publication type:

Article

Concluding Remarks.

Published in:

Annals of the New York Academy of Sciences, 1996, v. 803, n. 1, p. 327, doi. 10.1111/j.1749-6632.1996.tb26408.x

By:

GIOVANELLA, BEPPWO C.

Publication type:

Article

Phase I Clinical and Pharmacological Studies of 20-(S)-Camptothecin and 20-(S)-9-Nitrocamptothecin as Anticancer Agents.

Published in:

Annals of the New York Academy of Sciences, 1996, v. 803, n. 1, p. 224, doi. 10.1111/j.1749-6632.1996.tb26392.x

By:

NATELSON, ETHAN A.;
GIOVANELLA, BEPPINO C.;
VERSCHRAEGEN, CLAIRE F.;
FEHIR, KIM M.;
IPOLYI, PETER D.;
HARRIS, NICK;
STEHLIN, JOHN S.

Publication type:

Article

Clinical Studies of Topotecan.

Published in:

Annals of the New York Academy of Sciences, 1996, v. 803, n. 1, p. 264, doi. 10.1111/j.1749-6632.1996.tb26396.x

By:

BROOM, COLIN

Publication type:

Article

Induction of Apoptosis in Malignant and Camptothecin-resistant Human Cellsa.

Published in:

Annals of the New York Academy of Sciences, 1996, v. 803, n. 1, p. 143, doi. 10.1111/j.1749-6632.1996.tb26383.x

By:

CHATTERJEE, DEVASIS;
WYCHE, JAMES H.;
PANTAZIS, PANAYOTIS

Publication type:

Article

Cellular Resistance to Camptothecins.

Published in:

Annals of the New York Academy of Sciences, 1996, v. 803, n. 1, p. 60, doi. 10.1111/j.1749-6632.1996.tb26377.x

By:

POMMIER, YVES;
GUPTA, MALINI;
VALENTI, MONICA;
NIEVES-NEIRA, WILBERTO

Publication type:

Article

Synthesis of CPT-11 (Irinotecan Hydrochloride Trihydrate).

Published in:

Annals of the New York Academy of Sciences, 1996, v. 803, n. 1, p. 13, doi. 10.1111/j.1749-6632.1996.tb26372.x

By:

SAWADA, S.;
YOKOKURA, T.;
MIYASAKA, T.

Publication type:

Article

The Cell Cycle Effects of Camptothecina.

Published in:

Annals of the New York Academy of Sciences, 1996, v. 803, n. 1, p. 93, doi. 10.1111/j.1749-6632.1996.tb26379.x

By:

DARZYNKIEWICZ, ZBIGNIEW;
BRUNO, SILVIA;
BINO, GIACINTA;
TRAGANOS, FRANK

Publication type:

Article

Pharmacokinetic and Pharmacodynamic Studies of 9-Aminocamptothecin in Vitro against Human Cancer Cells.

Published in:

Annals of the New York Academy of Sciences, 1996, v. 803, n. 1, p. 315, doi. 10.1111/j.1749-6632.1996.tb26404.x

By:

LI, M.;
MOORE, M. J.;
BERRY, B.;
THIESSEN, J. J.

Publication type:

Article

Clinical Trials of Irinotecan Hydrochloride (CPT, Campto Injection, Topotecin Injection) in Japana.

Published in:

Annals of the New York Academy of Sciences, 1996, v. 803, n. 1, p. 292, doi. 10.1111/j.1749-6632.1996.tb26399.x

By:

SAIJO, NAGAHIRO

Publication type:

Article

Failure in DNA Elongation Predicts Sensitivity to Camptothecin in the Colon Cell Lines of the NCI Anticancer Drug Screen.

Published in:

Annals of the New York Academy of Sciences, 1996, v. 803, n. 1, p. 308, doi. 10.1111/j.1749-6632.1996.tb26401.x

By:

GOLDWASSER, FRANCOIS;
SHIMIZU, TSUNEHIRO;
POMMIER, YVES

Publication type:

Article

Topoisomerase-I Inhibitors in the Management of Colon Cancer.

Published in:

Annals of the New York Academy of Sciences, 1996, v. 803, n. 1, p. 256, doi. 10.1111/j.1749-6632.1996.tb26395.x

By:

WILLSON, JAMES K. V.

Publication type:

Article

Clinical Pharmacology and Pharmacodynamics of Irinotecan.

Published in:

Annals of the New York Academy of Sciences, 1996, v. 803, n. 1, p. 164, doi. 10.1111/j.1749-6632.1996.tb26385.x

By:

CHABOT, GUY G.

Publication type:

Article

Pharmacokinetics of Camptothecins Administered Orallya.

Published in:

Annals of the New York Academy of Sciences, 1996, v. 803, n. 1, p. 157, doi. 10.1111/j.1749-6632.1996.tb26384.x

By:

LIEHR, JOACHIM G.;
AHMED, AHMED E.;
GIOVANELLA, BEPPINO C.

Publication type:

Article

Factors Affecting Topotecan Sensitivity in Human Leukemia Samplesa.

Published in:

Annals of the New York Academy of Sciences, 1996, v. 803, n. 1, p. 128, doi. 10.1111/j.1749-6632.1996.tb26382.x

By:

KAUFMANN, SCOTT H.;
GORE, STEVEN D.;
LETENDRE, LOUIS;
SVINGEN, PHYLLIS A.;
KOTTKE, TIMOTHY;
BUCKWALTER, CHRISTOPHER A.;
JONES, RICHARD J.;
GROCHOW, LOUISE B.;
BURKE, PHILIP J.;
DONEHOWER, ROSS C.;
ROWINSKY, ERIC K.

Publication type:

Article

Camptothecin Resistance Related to Drug-induced Down-Regulation of Topoisomerase I and to Steps Occurring after the Formation of Protein-linked DNA Breaksa.

Published in:

Annals of the New York Academy of Sciences, 1996, v. 803, n. 1, p. 74, doi. 10.1111/j.1749-6632.1996.tb26378.x

By:

MURREN, JOHN R.;
BEIDLER, DAVID R.;
CHENG, YUNG CHI

Publication type:

Article

Introduction and Overview.

Published in:

Annals of the New York Academy of Sciences, 1996, v. 803, n. 1, p. ix, doi. 10.1111/j.1749-6632.1996.tb26370.x

By:

STEHLIN, JOHN S.

Publication type:

Article

Second Generation Synthesis of (20S)-Camptothecin and Derivatives via a Cascade Radical Reaction.

Published in:

Annals of the New York Academy of Sciences, 1996, v. 803, n. 1, p. 310, doi. 10.1111/j.1749-6632.1996.tb26402.x

By:

CURRAN, DENNIS P.;
JOSIEN, HUBERT;
KO, SUNG-BO

Publication type:

Article

Lowered Phosphorylation of Topoisomerase I Is a Direct Reason for Reduced Sensitivity of L5178Y-S Cells to Camptothecin.

Published in:

Annals of the New York Academy of Sciences, 1996, v. 803, n. 1, p. 321, doi. 10.1111/j.1749-6632.1996.tb26406.x

By:

STARON, KRZYSZTOF;
KOWALSKA-LOTH, BARBARA;
SZUMIEL, IRENA

Publication type:

Article

Implications for the Use of Topoisomerase I Inhibitors in Treatment of Patients with Systemic Sclerosisa.

Published in:

Annals of the New York Academy of Sciences, 1996, v. 803, n. 1, p. 318, doi. 10.1111/j.1749-6632.1996.tb26405.x

By:

RUDNICKA, LIDIA;
CZUWARA, JOANNA;
BARUSIŃSKA, AGNIESZKA;
NOWICKA, URSZULA;
MAKIELA, BARBARA;
JABLONSKA, STEFANIA

Publication type:

Article

Induction of Apoptosis by Camptothecin and Topotecan.

Published in:

Annals of the New York Academy of Sciences, 1996, v. 803, n. 1, p. 101, doi. 10.1111/j.1749-6632.1996.tb26380.x

By:

TRAGANOS, FRANK;
SEITER, KAREN;
FELDMAN, ERIC;
HALICKA, H. DOROTA;
DARZYNKIEWICZ, ZBIGNIEW

Publication type:

Article

Protocols for the Treatment of Human Tumor Xenografts with Camptothecins.

Published in:

Annals of the New York Academy of Sciences, 1996, v. 803, n. 1, p. 181, doi. 10.1111/j.1749-6632.1996.tb26387.x

By:

GIOVANELLA, B. C.;
NATELSON, E.;
HARRIS, N.;
VARDEMAN, D.;
STEHLIN, J. S.

Publication type:

Article

Discovery to Clinica.

Published in:

Annals of the New York Academy of Sciences, 1996, v. 803, n. 1, p. 1, doi. 10.1111/j.1749-6632.1996.tb26371.x

By:

WALL, MONROE E.;
WANI, MANSUKH C.

Publication type:

Article

Mechanism of Action of Camptothecin.

Published in:

Annals of the New York Academy of Sciences, 1996, v. 803, n. 1, p. 44, doi. 10.1111/j.1749-6632.1996.tb26375.x

By:

Liu, Leroy F.;
Duann, Pu;
Lin, Ching-Tai;
D'Arpa, Peter;
Wu, Jiaxi

Publication type:

Article

Treatment of Central Nervous System Xenografts with Camptothecins.

Published in:

Annals of the New York Academy of Sciences, 1996, v. 803, n. 1, p. 210, doi. 10.1111/j.1749-6632.1996.tb26390.x

By:

FRIEDMAN, HENRY S.;
HOUGHTON, PETER J.

Publication type:

Article

Clinical Pharmacology of 9-Aminocamptothecin.

Published in:

Annals of the New York Academy of Sciences, 1996, v. 803, n. 1, p. 324, doi. 10.1111/j.1749-6632.1996.tb26407.x

By:

TAKIMOTO, CHRIS H.;
DAHUT, WILLIAM;
HAROLD, NANCY;
NAKASHIMA, HAJIME;
LIEBERMAN, RONALD;
LIANG, MICHAEL D.;
ARBUCK, SUSAN G.;
CHEN, ALICE P.;
HAMILTON, J. MICHAEL;
CANTILENA, LOUIS R.;
ALLEGRA, CARMEN J.;
GREM, JEAN L.

Publication type:

Article

Cytotoxic Efficacy with Combinations of Topoisomerase I and Topoisomerase II Inhibitors in Sensitive and Multidrugresistant L1210 Mouse Leukemia Cellsa.

Published in:

Annals of the New York Academy of Sciences, 1996, v. 803, n. 1, p. 306, doi. 10.1111/j.1749-6632.1996.tb26400.x

By:

GRABOWSKI, DALE;
GANAPATHI, RAM

Publication type:

Article

Works matching IS 00778923 AND DT 1996 AND VI 803 AND IP 1

The Current Status of Irinotecan (CPT-11) in the United States.

Identification of Topoisomerase I Mutations Affecting Both DNA Cleavage and Interaction with Camptothecin<sup>a</sup>.

Trials of 9-Amino-20(S)-Camptothecin in Boston.

Schedule-dependent Efficacy of Camptothecins in Models of Human Cancer<sup>a</sup>.

The Effect of Camptothecin on Topoisomerase I Catalysis<sup>a</sup>.

Using Yeast to Understand Drugs that Target Topoisomerases<sup>a</sup>.

Chemistry of the Camptothecins in the Bloodstream.

Radiation Enhancement by 9-Aminocamptothecin.

9-Aminocamptothecin and Beyond.

Topoisomerase I Inhibition by the Camptothecin Analog G1147211C.

Preclinical Antitumor Activity and Pharmacokinetics of Irinotecan (CPT-11) in Tumor-bearing Mice.

CPT-11.

Camptothecin and Its Analogs.

Concluding Remarks.

Phase I Clinical and Pharmacological Studies of 20-(S)-Camptothecin and 20-(S)-9-Nitrocamptothecin as Anticancer Agents.

Clinical Studies of Topotecan.

Induction of Apoptosis in Malignant and Camptothecin-resistant Human Cells<sup>a</sup>.

Cellular Resistance to Camptothecins.

Synthesis of CPT-11 (Irinotecan Hydrochloride Trihydrate).

The Cell Cycle Effects of Camptothecin<sup>a</sup>.

Pharmacokinetic and Pharmacodynamic Studies of 9-Aminocamptothecin in Vitro against Human Cancer Cells.

Clinical Trials of Irinotecan Hydrochloride (CPT, Campto Injection, Topotecin Injection) in Japan<sup>a</sup>.

Failure in DNA Elongation Predicts Sensitivity to Camptothecin in the Colon Cell Lines of the NCI Anticancer Drug Screen.

Topoisomerase-I Inhibitors in the Management of Colon Cancer.

Clinical Pharmacology and Pharmacodynamics of Irinotecan.

Pharmacokinetics of Camptothecins Administered Orally<sup>a</sup>.

Factors Affecting Topotecan Sensitivity in Human Leukemia Samples<sup>a</sup>.

Camptothecin Resistance Related to Drug-induced Down-Regulation of Topoisomerase I and to Steps Occurring after the Formation of Protein-linked DNA Breaks<sup>a</sup>.

Introduction and Overview.

Second Generation Synthesis of (20S)-Camptothecin and Derivatives via a Cascade Radical Reaction.

Lowered Phosphorylation of Topoisomerase I Is a Direct Reason for Reduced Sensitivity of L5178Y-S Cells to Camptothecin.

Implications for the Use of Topoisomerase I Inhibitors in Treatment of Patients with Systemic Sclerosis<sup>a</sup>.

Induction of Apoptosis by Camptothecin and Topotecan.

Protocols for the Treatment of Human Tumor Xenografts with Camptothecins.

Discovery to Clinic<sup>a</sup>.

Mechanism of Action of Camptothecin.

Treatment of Central Nervous System Xenografts with Camptothecins.

Clinical Pharmacology of 9-Aminocamptothecin.

Cytotoxic Efficacy with Combinations of Topoisomerase I and Topoisomerase II Inhibitors in Sensitive and Multidrugresistant L1210 Mouse Leukemia Cells<sup>a</sup>.