Works in Xenobiotica, 2015, Vol 45, Issue 4

Results: 9

Age-related changes of hepatic clearances of cytochrome P450 probes, midazolam and R-/ S-warfarin in combination with caffeine, omeprazole and metoprolol in cynomolgus monkeys using in vitro-in vivo correlation.

Published in:

Xenobiotica, 2015, v. 45, n. 4, p. 312, doi. 10.3109/00498254.2014.979271

By:

Koyanagi, Takashi;
Nakanishi, Yasuharu;
Murayama, Norie;
Yamaura, Yoshiyuki;
Ikeda, Kanami;
Yano, Koji;
Uehara, Shotaro;
Utoh, Masahiro;
Kim, Soonih;
Uno, Yasuhiro;
Yamazaki, Hiroshi

Publication type:

Article

Metabolic profiling analysis of berberine, palmatine, jatrorrhizine, coptisine and epiberberine in zebrafish by ultra-high performance liquid chromatography coupled with LTQ Orbitrap mass spectrometer.

Published in:

Xenobiotica, 2015, v. 45, n. 4, p. 302, doi. 10.3109/00498254.2014.979270

By:

Li, Yan;
Wang, Hongjie;
Si, Nan;
Ren, Wei;
Han, Lingyu;
Xin, Shaokun;
Zuo, Ran;
Wei, Xiaolu;
Yang, Jian;
Zhao, Haiyu;
Bian, Baolin

Publication type:

Article

Physicochemical characteristics and gastrointestinal absorption behaviors of S-propargyl-cysteine, a potential new drug candidate for cardiovascular protection and antitumor treatment.

Published in:

Xenobiotica, 2015, v. 45, n. 4, p. 322, doi. 10.3109/00498254.2014.980369

By:

Ma, Guo;
Zhang, Lin;
Zhang, Peng;
Bao, Xingfei;
Zhou, Ning;
Shi, Qingling;
Zheng, Yuanting;
Liu, Hongrui;
Bu, Fengjiao;
Zhang, Ying;
Huang, Wenjie;
Wang, Fen;
Zhu, Yizhun;
Cai, Weimin

Publication type:

Article

Regulation of cerebral CYP2D alters tramadol metabolism in the brain: interactions of tramadol with propranolol and nicotine.

Published in:

Xenobiotica, 2015, v. 45, n. 4, p. 335, doi. 10.3109/00498254.2014.981609

By:

Wang, Qiaoli;
Han, Xiaotong;
Li, Jian;
Gao, Xinghui;
Wang, Yan;
Liu, Mingzhou;
Dong, Guicheng;
Yue, Jiang

Publication type:

Article

Comprehensive kinetic analysis and influence of reaction components for chlorzoxazone 6-hydroxylation in human liver microsomes with CYP antibodies.

Published in:

Xenobiotica, 2015, v. 45, n. 4, p. 353, doi. 10.3109/00498254.2014.985760

By:

Yamamura, Yoshiya;
Koyama, Noriyuki;
Umehara, Ken

Publication type:

Article

Reactive metabolite activation by CYP2C19-mediated rhein hepatotoxicity.

Published in:

Xenobiotica, 2015, v. 45, n. 4, p. 361, doi. 10.3109/00498254.2014.984794

By:

He, Li-Na;
Yang, Ai-Hong;
Cui, Tian-Yi;
Zhai, Yi-Ran;
Zhang, Fang-Liang;
Chen, Jun-Xiu;
Jin, Chun-Huan;
Fan, Yao-Wen;
Wu, Zi-Jun;
Wang, Li-Li;
He, Xin

Publication type:

Article

Species differences and substrate specificity of CYP3A heteroactivation by efavirenz.

Published in:

Xenobiotica, 2015, v. 45, n. 4, p. 345, doi. 10.3109/00498254.2014.981610

By:

Kosugi, Yohei;
Takahashi, Junzo

Publication type:

Article

Investigation of the prerequisites for the optimization of specific plasma protein binding as a strategy for the reduction of first-pass hepatic metabolism.

Published in:

Xenobiotica, 2015, v. 45, n. 4, p. 286, doi. 10.3109/00498254.2014.978413

By:

Svennebring, Andreas Mats

Publication type:

Article

Effects of tetrahydroxystilbene glucoside on mouse liver cytochrome P450 enzyme expressions.

Published in:

Xenobiotica, 2015, v. 45, n. 4, p. 279, doi. 10.3109/00498254.2014.976779

By:

Wang, Yan-Ying;
Yang, Jun;
Liu, Hang;
Lin, Feng-Qin;
Shi, Jing-Shan;
Zhang, Feng

Publication type:

Article