Works matching IS 00219738 AND DT 2020 AND VI 130 AND IP 3

Results: 48

Oral N-acetylcysteine improves cone function in retinitis pigmentosa patients in phase I trial.
Published in:
2020
By:
- Campochiaro, Peter A.;
- Iftikhar, Mustafa;
- Hafiz, Gulnar;
- Akhlaq, Anam;
- Grace Tsai;
- Wehling, Dagmar;
- Lili Lu;
- Wall, G. Michael;
- Singh, Mandeep S.;
- Xiangrong Kong;
- Tsai, Grace;
- Lu, Lili;
- Kong, Xiangrong
Publication type:
journal article
Glycerol-3-phosphate is an FGF23 regulator derived from the injured kidney.
Published in:
2020
By:
- Simic, Petra;
- Kim, Wondong;
- Wen Zhou;
- Pierce, Kerry A.;
- Chang, Wenhan;
- Sykes, David B.;
- Aziz, Najihah B.;
- Elmariah, Sammy;
- Ngo, Debby;
- Pajevic, Paola Divieti;
- Govea, Nicolas;
- Kestenbaum, Bryan R.;
- de Boer, Ian H.;
- Zhiqiang Cheng;
- Christov, Marta;
- Chun, Jerold;
- Leaf, David E.;
- Waikar, Sushrut S.;
- Tager, Andrew M.;
- Gerszten, Robert E.
Publication type:
journal article
Dominant mutations of the Notch ligand Jagged1 cause peripheral neuropathy.
Published in:
2020
By:
- Sullivan, Jeremy M.;
- Motley, William W.;
- Johnson, Janel O.;
- Aisenberg, William H.;
- Marshall, Katherine L.;
- Barwick, Katy E. S.;
- Lingling Kong;
- Huh, Jennifer S.;
- Saavedra-Rivera, Pamela C.;
- McEntagart, Meriel M.;
- Marion, Marie-Helene;
- Hicklin, Lucy A.;
- Modarres, Hamid;
- Baple, Emma L.;
- Farah, Mohamed H.;
- Zuberi, Aamir R.;
- Lutz, Cathleen M.;
- Gaudet, Rachelle;
- Traynor, Bryan J.;
- Crosby, Andrew H.
Publication type:
journal article
Myalgic encephalomyelitis/chronic fatigue syndrome patients exhibit altered T cell metabolism and cytokine associations.
Published in:
2020
By:
- Mandarano, Alexandra H.;
- Maya, Jessica;
- Giloteaux, Ludovic;
- Peterson, Daniel L.;
- Maynard, Marco;
- Gottschalk, C. Gunnar;
- Hanson, Maureen R.
Publication type:
journal article
DGCR8 microprocessor defect characterizes familial multinodular goiter with schwannomatosis.
Published in:
2020
By:
- Rivera, Barbara;
- Nadaf, Javad;
- Fahiminiya, Somayyeh;
- Apellaniz-Ruiz, Maria;
- Saskin, Avi;
- Chong, Anne-Sophie;
- Sharma, Sahil;
- Wagener, Rabea;
- Revil, Timothée;
- Condello, Vincenzo;
- Harra, Zineb;
- Hamel, Nancy;
- Sabbaghian, Nelly;
- Muchantef, Karl;
- Thomas, Christian;
- de Kock, Leanne;
- Hébert-Blouin, Marie-Noëlle;
- Bassenden, Angelia V.;
- Rabenstein, Hannah;
- Mete, Ozgur
Publication type:
journal article
Chikungunya virus replication in skeletal muscle cells is required for disease development.
Published in:
2020
By:
- Lentscher, Anthony J.;
- McCarthy, Mary K.;
- May, Nicholas A.;
- Davenport, Bennett J.;
- Montgomery, Stephanie A.;
- Raghunathan, Krishnan;
- McAllister, Nicole;
- Silva, Laurie A.;
- Morrison, Thomas E.;
- Dermody, Terence S.
Publication type:
journal article
Neuromuscular junctions are stable in patients with cancer cachexia.
Published in:
2020
By:
- Boehm, Ines;
- Miller, Janice;
- Wishart, Thomas M.;
- Wigmore, Stephen J.;
- Skipworth, Richard J. E.;
- Jones, Ross A.;
- Gillingwater, Thomas H.;
- Skipworth, Richard Je
Publication type:
journal article
Insulin resistance drives hepatic de novo lipogenesis in nonalcoholic fatty liver disease.
Published in:
2020
By:
- Smith, Gordon I.;
- Shankaran, Mahalakshmi;
- Mihoko Yoshino;
- Schweitzer, George G.;
- Chondronikola, Maria;
- Beals, Joseph W.;
- Okunade, Adewole L.;
- Patterson, Bruce W.;
- Nyangau, Edna;
- Field, Tyler;
- Sirlin, Claude B.;
- Talukdar, Saswata;
- Hellerstein, Marc K.;
- Klein, Samuel;
- Yoshino, Mihoko
Publication type:
journal article
Impaired folate 1-carbon metabolism causes formate-preventable hydrocephalus in glycine decarboxylase-deficient mice.
Published in:
2020
By:
- Santos, Chloe;
- Yun Jin Pai;
- Mahmood, M. Raasib;
- Kit-Yi Leung;
- Savery, Dawn;
- Waddington, Simon N.;
- Copp, Andrew J.;
- Greene, Nicholas D. E.;
- Pai, Yun Jin;
- Leung, Kit-Yi;
- Greene, Nicholas DE
Publication type:
journal article
Lysine acetyltransferase 8 is involved in cerebral development and syndromic intellectual disability.
Published in:
2020
By:
- Lin Li;
- Ghorbani, Mohammad;
- Weisz-Hubshman, Monika;
- Rousseau, Justine;
- Thiffault, Isabelle;
- Schnur, Rhonda E.;
- Breen, Catherine;
- Oegema, Renske;
- Weiss, Marjan M. M.;
- Waisfisz, Quinten;
- Welner, Sara;
- Kingston, Helen;
- Hills, Jordan A.;
- Boon, Elles M. J.;
- Basel-Salmon, Lina;
- Konen, Osnat;
- Goldberg-Stern, Hadassa;
- Bazak, Lily;
- Tzur, Shay;
- Jin, Jianliang
Publication type:
journal article
IL-36γ drives skin toxicity induced by EGFR/MEK inhibition and commensal Cutibacterium acnes.
Published in:
2020
By:
- Satoh, Takashi K.;
- Mellett, Mark;
- Meier-Schiesser, Barbara;
- Fenini, Gabriele;
- Atsushi Otsuka;
- Beer, Hans-Dietmar;
- Rordorf, Tamara;
- Maul, Julia-Tatjana;
- Jürg Hafner;
- Navarini, Alexander A.;
- Contassot, Emmanuel;
- French, Lars E.;
- Otsuka, Atsushi;
- Hafner, Jürg
Publication type:
journal article
A conserved intratumoral regulatory T cell signature identifies 4-1BB as a pan-cancer target.
Published in:
2020
By:
- Freeman, Zachary T.;
- Nirschl, Thomas R.;
- Hovelson, Daniel H.;
- Johnston, Robert J.;
- Engelhardt, John J.;
- Selby, Mark J.;
- Kochel, Christina M.;
- Lan, Ruth Y.;
- Jingyi Zhai;
- Ghasemzadeh, Ali;
- Gupta, Anuj;
- Skaist, Alyza M.;
- Wheelan, Sarah J.;
- Hui Jiang;
- Pearson, Alexander T.;
- Snyder, Linda A.;
- Korman, Alan J.;
- Tomlins, Scott A.;
- Yegnasubramanian, Srinivasan;
- Drake, Charles G.
Publication type:
journal article
Cardioprotective GLP-1 metabolite prevents ischemic cardiac injury by inhibiting mitochondrial trifunctional protein-α.
Published in:
2020
By:
- Siraj, M. Ahsan;
- Mundi, Dhanwantee;
- Beca, Sanja;
- Momen, Abdul;
- Shikatani, Eric A.;
- Afroze, Talat;
- Xuetao Sun;
- Ying Liu;
- Ghaffari, Siavash;
- Lee, Warren;
- Wheeler, Michael B.;
- Keller, Gordon;
- Backx, Peter;
- Husain, Mansoor;
- Mundil, Dhanwantee;
- Sun, Xuetao;
- Liu, Ying
Publication type:
journal article
Microphthalmia transcription factor expression contributes to bone marrow failure in Fanconi anemia.
Published in:
2020
By:
- Oppezzo, Alessia;
- Bourseguin, Julie;
- Renaud, Emilie;
- Pawlikowska, Patrycja;
- Rosselli, Filippo
Publication type:
journal article
Machine learning reveals serum sphingolipids as cholesterol-independent biomarkers of coronary artery disease.
Published in:
2020
By:
- Poss, Annelise M.;
- Maschek, J. Alan;
- Cox, James E.;
- Hauner, Benedikt J.;
- Hopkins, Paul N.;
- Hunt, Steven C.;
- Holland, William L.;
- Summers, Scott A.;
- Playdon, Mary C.
Publication type:
journal article
Prion protein glycans reduce intracerebral fibril formation and spongiosis in prion disease.
Published in:
2020
By:
- Sevillano, Alejandro M.;
- Aguilar-Calvo, Patricia;
- Kurt, Timothy D.;
- Lawrence, Jessica A.;
- Soldau, Katrin;
- Nam, Thu H.;
- Schumann, Taylor;
- Pizzo, Donald P.;
- Nyström, Sofie;
- Choudhury, Biswa;
- Altmeppen, Hermann;
- Esko, Jeffrey D.;
- Glatzel, Markus;
- Nilsson, K. Peter R.;
- Sigurdson, Christina J.
Publication type:
journal article
GABA interneurons are the cellular trigger for ketamine's rapid antidepressant actions.
Published in:
2020
By:
- Gerhard, Danielle M.;
- Pothula, Santosh;
- Rong-Jian Liu;
- Min Wu;
- Xiao-Yuan Li;
- Girgenti, Matthew J.;
- Taylor, Seth R.;
- Duman, Catharine H.;
- Delpire, Eric;
- Picciotto, Marina;
- Wohleb, Eric S.;
- Duman, Ronald S.;
- Liu, Rong-Jian;
- Wu, Min;
- Li, Xiao-Yuan
Publication type:
journal article
The anti-IgE mAb omalizumab induces adverse reactions by engaging Fcγ receptors.
Published in:
2020
By:
- Balbino, Bianca;
- Herviou, Pauline;
- Godon, Ophélie;
- Stackowicz, Julien;
- Goff, Odile Richard-Le;
- Iannascoli, Bruno;
- Sterlin, Delphine;
- Brûlé, Sébastien;
- Millot, Gael A.;
- Harris, Faith M.;
- Voronina, Vera A.;
- Nadeau, Kari C.;
- Macdonald, Lynn E.;
- Murphy, Andrew J.;
- Bruhns, Pierre;
- Reber, Laurent L.
Publication type:
journal article
Graft-versus-host disease of the CNS is mediated by TNF upregulation in microglia.
Published in:
2020
By:
- Mathew, Nimitha R.;
- Vinnakota, Janaki M.;
- Apostolova, Petya;
- Erny, Daniel;
- Hamarsheh, Shaimaa;
- Andrieux, Geoffroy;
- Jung-Seok Kim;
- Hanke, Kathrin;
- Goldmann, Tobias;
- Chappell-Maor, Louise;
- El-Khawanky, Nadia;
- Ihorst, Gabriele;
- Schmidt, Dominik;
- Duyster, Justus;
- Finke, Jürgen;
- Blank, Thomas;
- Boerries, Melanie;
- Blazar, Bruce R.;
- Jung, Steffen;
- Prinz, Marco
Publication type:
journal article
Linear ubiquitin assembly complex regulates lung epithelial-driven responses during influenza infection.
Published in:
2020
By:
- Brazee, Patricia L.;
- Morales-Nebreda, Luisa;
- Magnani, Natalia D.;
- Garcia, Joe G. N.;
- Misharin, Alexander V.;
- Ridge, Karen M.;
- Budinger, G. R. Scott;
- Iwai, Kazuhiro;
- Dada, Laura A.;
- Sznajder, Jacob I.;
- Garcia, Joe Gn
Publication type:
journal article
Oral immunotherapy tolerizes mice to enzyme replacement therapy for Morquio A syndrome.
Published in:
2020
By:
- Sosa, Angela C.;
- Kariuki, Barbara;
- Qi Gan;
- Knutsen, Alan P.;
- Bellone, Clifford J.;
- Guzmán, Miguel A.;
- Barrera, Luis A.;
- Shunji Tomatsu;
- Chauhan, Anil K.;
- Armbrecht, Eric;
- Montaño, Adriana M.;
- Gan, Qi;
- Tomatsu, Shunji
Publication type:
journal article
Muscle-specific SMN reduction reveals motor neuron-independent disease in spinal muscular atrophy models.
Published in:
2020
By:
- Jeong-Ki Kim;
- Jha, Narendra N.;
- Zhihua Feng;
- Faleiro, Michelle R.;
- Chiriboga, Claudia A.;
- Lan Wei-Lapierre;
- Dirksen, Robert T.;
- Chien-Ping Ko;
- Monani, Umrao R.;
- Kim, Jeong-Ki;
- Feng, Zhihua;
- Wei-Lapierre, Lan;
- Ko, Chien-Ping
Publication type:
journal article
Inactivation of endothelial ZEB1 impedes tumor progression and sensitizes tumors to conventional therapies.
Published in:
2020
By:
- Rong Fu;
- Yi Li;
- Nan Jiang;
- Bo-Xue Ren;
- Chen-Zi Zang;
- Li-Juan Liu;
- Wen-Cong Lv;
- Hong-Mei Li;
- Weiss, Stephen;
- Zheng-Yu Li;
- Tao Lu;
- Zhao-Qiu Wu;
- Fu, Rong;
- Li, Yi;
- Jiang, Nan;
- Ren, Bo-Xue;
- Zang, Chen-Zi;
- Liu, Li-Juan;
- Lv, Wen-Cong;
- Li, Hong-Mei
Publication type:
journal article
Chronic mTOR activation induces a degradative smooth muscle cell phenotype.
Published in:
2020
By:
- Guangxin Li;
- Mo Wang;
- Caulk, Alexander W.;
- Cilfone, Nicholas A.;
- Gujja, Sharvari;
- Lingfeng Qin;
- Pei-Yu Chen;
- Zehua Chen;
- Yousef, Sameh;
- Yang Jiao;
- Changshun He;
- Bo Jiang;
- Korneva, Arina;
- Bersi, Matthew R.;
- Guilin Wang;
- Xinran Liu;
- Mehta, Sameet;
- Geirsson, Arnar;
- Gulcher, Jeffrey R.;
- Chittenden, Thomas W.
Publication type:
journal article
A stress-responsive enhancer induces dynamic drug resistance in acute myeloid leukemia.
Published in:
2020
By:
- Williams, Mark S.;
- Amaral, Fabio M. R.;
- Simeoni, Fabrizio;
- Somervaille, Tim C. P.;
- Amaral, Fabio Mr;
- Somervaille, Tim Cp
Publication type:
journal article
Antiangiogenic immunotherapy suppresses desmoplastic and chemoresistant intestinal tumors in mice.
Published in:
2020
By:
- Ragusa, Simone;
- Prat-Luri, Borja;
- González-Loyola, Alejandra;
- Nassiri, Sina;
- Leonardo Squadrito, Mario;
- Guichard, Alan;
- Cavin, Sabrina;
- Gjorevski, Nikolce;
- Barras, David;
- Marra, Giancarlo;
- Lutolf, Matthias P.;
- Perentes, Jean;
- Corse, Emily;
- Bianchi, Roberta;
- Wetterwald, Laureline;
- Jaeryung Kim;
- Oliver, Guillermo;
- Delorenzi, Mauro;
- De Palma, Michele;
- Petrova, Tatiana V.
Publication type:
journal article
CD73 immune checkpoint defines regulatory NK cells within the tumor microenvironment.
Published in:
2020
By:
- Shi Yong Neo;
- Ying Yang;
- Record, Julien;
- Ran Ma;
- Xinsong Chen;
- Ziqing Chen;
- Tobin, Nicholas P.;
- Blake, Emily;
- Seitz, Christina;
- Thomas, Ron;
- Wagner, Arnika Kathleen;
- Andersson, John;
- de Boniface, Jana;
- Bergh, Jonas;
- Murray, Shannon;
- Alici, Evren;
- Childs, Richard;
- Johansson, Martin;
- Westerberg, Lisa S.;
- Haglund, Felix
Publication type:
journal article
D1-mGlu5 heteromers mediate noncanonical dopamine signaling in Parkinson's disease.
Published in:
2020
By:
- Sebastianutto, Irene;
- Goyet, Elise;
- Andreoli, Laura;
- Font-Ingles, Joan;
- Moreno-Delgado, David;
- Bouquier, Nathalie;
- Jahannault-Talignani, Céline;
- Moutin, Enora;
- Di Menna, Luisa;
- Maslava, Natallia;
- Pin, Jean-Philippe;
- Fagni, Laurent;
- Nicoletti, Ferdinando;
- Ango, Fabrice;
- Cenci, M. Angela;
- Perroy, Julie
Publication type:
journal article
Annexin A1 drives macrophage skewing to accelerate muscle regeneration through AMPK activation.
Published in:
2020
By:
- McArthur, Simon;
- Juban, Gaëtan;
- Gobbetti, Thomas;
- Desgeorges, Thibaut;
- Theret, Marine;
- Gondin, Julien;
- Toller-Kawahisa, Juliana E.;
- Reutelingsperger, Chris P.;
- Chazaud, Bénédicte;
- Perretti, Mauro;
- Mounier, Rémi
Publication type:
journal article
Shortened TDP43 isoforms upregulated by neuronal hyperactivity drive TDP43 pathology in ALS.
Published in:
2020
By:
- Weskamp, Kaitlin;
- Tank, Elizabeth M.;
- Miguez, Roberto;
- McBride, Jonathon P.;
- Gómez, Nicolás B.;
- White, Matthew;
- Ziqiang Lin;
- Moreno Gonzalez, Carmen;
- Serio, Andrea;
- Sreedharan, Jemeen;
- Barmada, Sami J.;
- Lin, Ziqiang;
- Gonzalez, Carmen Moreno
Publication type:
journal article
CD8+ T cells target cerebrovasculature in children with cerebral malaria.
Published in:
2020
By:
- Riggle, Brittany A.;
- Manglani, Monica;
- Maric, Dragan;
- Johnson, Kory R.;
- Myoung-Hwa Lee;
- Lopes Abath Neto, Osorio;
- Taylor, Terrie E.;
- Seydel, Karl B.;
- Nath, Avindra;
- Miller, Louis H.;
- McGavern, Dorian B.;
- Pierce, Susan K.;
- Lee, Myoung-Hwa;
- Neto, Osorio Lopes Abath
Publication type:
journal article
Staphylococcus aureus toxin suppresses antigen-specific T cell responses.
Published in:
2020
By:
- Lee, Brandon;
- Olaniyi, Reuben;
- Kwiecinski, Jakub M.;
- Wardenburg, Juliane Bubeck;
- Kwiecinski, Jakub;
- Bubeck Wardenburg, Juliane
Publication type:
journal article
Glibenclamide reverses cardiovascular abnormalities of Cantu syndrome driven by KATP channel overactivity.
Published in:
2020
By:
- McClenaghan, Conor;
- Yan Huang;
- Zihan Yan;
- Harter, Theresa M.;
- Halabi, Carmen M.;
- Chalk, Rod;
- Kovacs, Attila;
- van Haaften, Gijs;
- Remedi, Maria S.;
- Nichols, Colin G.;
- Huang, Yan;
- Yan, Zihan;
- Harter, Theresa
Publication type:
journal article
The surprising complexity of KATP channel biology and of genetic diseases.
Published in:
2020
By:
- Guiling Zhao;
- Kaplan, Aaron;
- Greiser, Maura;
- Lederer, W. Jonathan;
- Zhao, Guiling
Publication type:
journal article
CD8+ T cells and human cerebral malaria: a shifting episteme.
Published in:
2020
By:
- Rénia, Laurent;
- Grau, Georges E. R.;
- Wassmer, Samuel C.;
- Grau, Georges Er
Publication type:
journal article
Kidney to bone via bedside to bench…and back?
Published in:
2020
By:
- Grabner, Alexander;
- Wolf, Myles
Publication type:
journal article
Can the light of immunometabolism cut through "brain fog"?
Published in:
2020
By:
- Hornig, Mady
Publication type:
journal article
Chikungunya infection: de-linking replication from symptomatology reveals the central role of muscle.
Published in:
2020
By:
- Moscona, Anne
Publication type:
journal article
Proliferative, degradative smooth muscle cells promote aortic disease.
Published in:
2020
By:
- Hulsmans, Maarten;
- Nahrendorf, Matthias
Publication type:
journal article
How the matrix metalloproteinase MMP14 contributes to the progression of colorectal cancer.
Published in:
2020
By:
- Claesson-Welsh, Lena
Publication type:
journal article
When bugs and drugs conspire: driving acneiform skin toxicity.
Published in:
2020
By:
- Billi, Allison C.;
- Sarkar, Mrinal K.;
- Gudjonsson, Johann E.
Publication type:
journal article
Underglycosylated prion protein modulates plaque formation in the brain.
Published in:
2020
By:
- Bartz, Jason C.
Publication type:
journal article
Breaking through the surface: more to learn about lipids and cardiovascular disease.
Published in:
2020
By:
- Echouffo-Tcheugui, Justin B.;
- Jain, Mohit;
- Cheng, Susan
Publication type:
journal article
Senescent T cells within suppressive tumor microenvironments: emerging target for tumor immunotherapy.
Published in:
2020
By:
- Xia Liu;
- Hoft, Daniel F.;
- Guangyong Peng;
- Liu, Xia;
- Peng, Guangyong
Publication type:
journal article
The multifaceted role of ischemia/reperfusion in sickle cell anemia.
Published in:
2020
By:
- Hebbel, Robert P.;
- Belcher, John D.;
- Vercellotti, Gregory M.
Publication type:
journal article
Addressing the physician-scientist pipeline: strategies to integrate research into clinical training programs.
Published in:
2020
By:
- Permar, Sallie R.;
- Ward, Rebecca A.;
- Barrett, Katherine J.;
- Freel, Stephanie A.;
- Gbadegesin, Rasheed A.;
- Kontos, Christopher D.;
- Hu, Patrick J.;
- Hartmann, Katherine E.;
- Williams, Christopher S.;
- Vyas, Jatin M.
Publication type:
journal article
Stable ischemic heart disease: how to keep it that way.
Published in:
2020
By:
- Leucker, Thorsten M.;
- Schulman, Steven P.;
- Gerstenblith, Gary
Publication type:
journal article
A conversation with Barbara Kahn.
Published in:
2020
By:
- Neill, Ushma S.
Publication type:
journal article