Works matching IS 00219738 AND DT 2016 AND VI 126 AND IP 9

Results: 40

Transcription factor TBX4 regulates myofibroblast accumulation and lung fibrosis.

Published in:

2016

By:

Xie, Ting;
Liang, Jiurong;
Liu, Ningshan;
Huan, Caijuan;
Zhang, Yanli;
Liu, Weijia;
Kumar, Maya;
Xiao, Rui;
D'Armiento, Jeanine;
Metzger, Daniel;
Chambon, Pierre;
Papaioannou, Virginia E;
Stripp, Barry R;
Jiang, Dianhua;
Noble, Paul W

Publication type:

journal article

Hotspot autoimmune T cell receptor binding underlies pathogen and insulin peptide cross-reactivity.

Published in:

2016

By:

Cole, David K;
Bulek, Anna M;
Dolton, Garry;
Schauenberg, Andrea J;
Szomolay, Barbara;
Rittase, William;
Trimby, Andrew;
Jothikumar, Prithiviraj;
Fuller, Anna;
Skowera, Ania;
Rossjohn, Jamie;
Zhu, Cheng;
Miles, John J;
Peakman, Mark;
Wooldridge, Linda;
Rizkallah, Pierre J;
Sewell, Andrew K

Publication type:

journal article

PIK3C2B inhibition improves function and prolongs survival in myotubular myopathy animal models.

Published in:

2016

By:

Sabha, Nesrin;
Volpatti, Jonathan R.;
Gonorazky, Hernan;
Reifler, Aaron;
Davidson, Ann E.;
Xingli Li;
Eltayeb, Nadine M.;
Dall'Armi, Claudia;
Di Paolo, Gilbert;
Brooks, Susan V.;
Buj-Bello, Ana;
Feldman, Eva L.;
Dowling, James J.;
Li, Xingli

Publication type:

journal article

Urea impairs β cell glycolysis and insulin secretion in chronic kidney disease.

Published in:

2016

By:

Koppe, Laetitia;
Nyam, Elsa;
Vivot, Kevin;
Manning Fox, Jocelyn E.;
Xiao-Qing Dai;
Nguyen, Bich N.;
Trudel, Dominique;
Attané, Camille;
Moullé, Valentine S.;
MacDonald, Patrick E.;
Ghislain, Julien;
Poitout, Vincent;
Dai, Xiao-Qing

Publication type:

journal article

Serine 421 regulates mutant huntingtin toxicity and clearance in mice.

Published in:

2016

By:

Kratter, Ian H.;
Zahed, Hengameh;
Lau, Alice;
Tsvetkov, Andrey S.;
Daub, Aaron C.;
Weiberth, Kurt F.;
Xiaofeng Gu;
Saudou, Frédéric;
Humbert, Sandrine;
Yang, X. William;
Osmand, Alex;
Steffan, Joan S.;
Masliah, Eliezer;
Finkbeiner, Steven;
Gu, Xiaofeng

Publication type:

journal article

Biallelic inactivation of REV7 is associated with Fanconi anemia.

Published in:

2016

By:

Bluteau, Dominique;
Masliah-Planchon, Julien;
Clairmont, Connor;
Rousseau, Alix;
Ceccaldi, Raphael;
Dubois d'Enghien, Catherine;
Bluteau, Olivier;
Cuccuini, Wendy;
Gachet, Stéphanie;
de Latour, Régis Peffault;
Leblanc, Thierry;
Socié, Gérard;
Baruchel, André;
Stoppa-Lyonnet, Dominique;
D'Andrea, Alan D.;
Soulier, Jean;
Peffault de Latour, Régis

Publication type:

journal article

MondoA coordinately regulates skeletal myocyte lipid homeostasis and insulin signaling.

Published in:

2016

By:

Byungyong Ahn;
Soundarapandian, Mangala M.;
Sessions, Hampton;
Peddibhotla, Satyamaheshwar;
Roth, Gregory P.;
Jian-Liang Li;
Sugarman, Eliot;
Koo, Ada;
Malany, Siobhan;
Miao Wang;
Kyungmoo Yea;
Brooks, Jeanne;
Leone, Teresa C.;
Xianlin Han;
Vega, Rick B.;
Kelly, Daniel P.;
Ahn, Byungyong;
Li, Jian-Liang;
Wang, Miao;
Yea, Kyungmoo

Publication type:

journal article

Mitochondrial calcium uptake underlies ROS generation during aminoglycoside-induced hair cell death.

Published in:

2016

By:

Esterberg, Robert;
Linbo, Tor;
Pickett, Sarah B.;
Wu, Patricia;
Ou, Henry C.;
Rubel, Edwin W.;
Raible, David W.

Publication type:

journal article

A colitogenic memory CD4+ T cell population mediates gastrointestinal graft-versus-host disease.

Published in:

2016

By:

Zhou, Vivian;
Agle, Kimberle;
Xiao Chen;
Beres, Amy;
Komorowski, Richard;
Belle, Ludovic;
Taylor, Carolyn;
Fenlu Zhu;
Haribhai, Dipica;
Williams, Calvin B.;
Verbsky, James;
Blumenschein, Wendy;
Sadekova, Svetlana;
Bowman, Eddie;
Ballantyne, Christie;
Weaver, Casey;
Serody, David A.;
Vincent, Benjamin;
Serody, Jonathan;
Cua, Daniel J.

Publication type:

journal article

Mechanistically distinct cancer-associated mTOR activation clusters predict sensitivity to rapamycin.

Published in:

2016

By:

Jianing Xu;
Pham, Can G.;
Albanese, Steven K.;
Yiyu Dong;
Toshinao Oyama;
Chung-Han Lee;
Rodrik-Outmezguine, Vanessa;
Zhan Yao;
Song Han;
Chen, David;
Parton, Daniel L.;
Chodera, John D.;
Rosen, Neal;
Cheng, Emily H.;
Hsieh, James J.;
Xu, Jianing;
Dong, Yiyu;
Oyama, Toshinao;
Lee, Chung-Han;
Yao, Zhan

Publication type:

journal article

Opposing actions of angiopoietin-2 on Tie2 signaling and FOXO1 activation.

Published in:

2016

By:

Kim, Minah;
Allen, Breanna;
Korhonen, Emilia A.;
Nitschké, Maximilian;
Hee Won Yang;
Baluk, Peter;
Saharinen, Pipsa;
Alitalo, Kari;
Daly, Christopher;
Thurston, Gavin;
McDonald, Donald M.;
Yang, Hee Won

Publication type:

journal article

Tie1 controls angiopoietin function in vascular remodeling and inflammation.

Published in:

2016

By:

Korhonen, Emilia A.;
Lampinen, Anita;
Giri, Hemant;
Anisimov, Andrey;
Kim, Minah;
Allen, Breanna;
Shentong Fang;
D'Amico, Gabriela;
Sipilä, Tuomas J.;
Lohela, Marja;
Strandin, Tomas;
Vaheri, Antti;
Ylä-Herttuala, Seppo;
Gou Young Koh;
McDonald, Donald M.;
Alitalo, Kari;
Saharinen, Pipsa;
Fang, Shentong;
Koh, Gou Young

Publication type:

journal article

BET bromodomain inhibition enhances T cell persistence and function in adoptive immunotherapy models.

Published in:

2016

By:

Yuki Kagoya;
Munehide Nakatsugawa;
Yuki Yamashita;
Toshiki Ochi;
Tingxi Guo;
Anczurowski, Mark;
Kayoko Saso;
Butler, Marcus O.;
Arrowsmith, Cheryl H.;
Naoto Hirano;
Kagoya, Yuki;
Nakatsugawa, Munehide;
Yamashita, Yuki;
Ochi, Toshiki;
Guo, Tingxi;
Saso, Kayoko;
Hirano, Naoto

Publication type:

journal article

β1-Adrenergic receptor deficiency in ghrelin-expressing cells causes hypoglycemia in susceptible individuals.

Published in:

2016

By:

Mani, Bharath K.;
Osborne-Lawrence, Sherri;
Vijayaraghavan, Prasanna;
Hepler, Chelsea;
Zigman, Jeffrey M.

Publication type:

journal article

Lymphatic vessels regulate immune microenvironments in human and murine melanoma.

Published in:

2016

By:

Lund, Amanda W.;
Wagner, Marek;
Fankhauser, Manuel;
Steinskog, Eli S.;
Broggi, Maria A.;
Spranger, Stefani;
Gajewski, Thomas F.;
Alitalo, Kari;
Eikesdal, Hans P.;
Wiig, Helge;
Swartz, Melody A.

Publication type:

journal article

Tumor immune profiling predicts response to anti-PD-1 therapy in human melanoma.

Published in:

2016

By:

Daud, Adil I.;
Loo, Kimberly;
Pauli, Mariela L.;
Sanchez-Rodriguez, Robert;
Munoz Sandoval, Priscila;
Taravati, Keyon;
Tsai, Katy;
Nosrati, Adi;
Nardo, Lorenzo;
Alvarado, Michael D.;
Algazi, Alain P.;
Pampaloni, Miguel H.;
Lobach, Iryna V.;
Hwang, Jimmy;
Pierce, Robert H.;
Gratz, Iris K.;
Krummel, Matthew F.;
Rosenblum, Michael D.;
Sandoval, Priscila Munoz

Publication type:

journal article

Insulin and IGF-1 receptors regulate FoxO-mediated signaling in muscle proteostasis.

Published in:

2016

By:

O'Neill, Brian T.;
Lee, Kevin Y.;
Klaus, Katherine;
Softic, Samir;
Krumpoch, Megan T.;
Fentz, Joachim;
Stanford, Kristin I.;
Robinson, Matthew M.;
Weikang Cai;
Kleinridders, Andre;
Pereira, Renata O.;
Hirshman, Michael F.;
Abel, E. Dale;
Accili, Domenico;
Goodyear, Laurie J.;
Nair, K. Sreekumaran;
Kahn, C. Ronald;
Cai, Weikang

Publication type:

journal article

Phase I trials using Sleeping Beauty to generate CD19-specific CAR T cells.

Published in:

2016

By:

Kebriaei, Partow;
Singh, Harjeet;
Huls, M. Helen;
Figliola, Matthew J.;
Bassett, Roland;
Olivares, Simon;
Jena, Bipulendu;
Dawson, Margaret J.;
Kumaresan, Pappanaicken R.;
Shihuang Su;
Maiti, Sourindra;
Jianliang Dai;
Moriarity, Branden;
Forget, Marie-Andrée;
Senyukov, Vladimir;
Orozco, Aaron;
Tingting Liu;
McCarty, Jessica;
Jackson, Rineka N.;
Moyes, Judy S.

Publication type:

journal article

Tyrosine kinase FYN negatively regulates NOX4 in cardiac remodeling.

Published in:

2016

By:

Shouji Matsushima;
Junya Kuroda;
Peiyong Zhai;
Tong Liu;
Shohei Ikeda;
Narayani Nagarajan;
Shin-ichi Oka;
Takashi Yokota;
Shintaro Kinugawa;
Chiao-Po Hsu;
Hong Li;
Hiroyuki Tsutsui;
Junichi Sadoshima;
Matsushima, Shouji;
Kuroda, Junya;
Zhai, Peiyong;
Liu, Tong;
Ikeda, Shohei;
Nagarajan, Narayani;
Oka, Shin-Ichi

Publication type:

journal article

Granulocyte macrophage colony-stimulating factor induces CCL17 production via IRF4 to mediate inflammation.

Published in:

2016

By:

Achuthan, Adrian;
Cook, Andrew D.;
Ming-Chin Lee;
Saleh, Reem;
Hsu-Wei Khiew;
Chang, Melody W. N.;
Louis, Cynthia;
Fleetwood, Andrew J.;
Lacey, Derek C.;
Christensen, Anne D.;
Frye, Ashlee T.;
Pui Yeng Lam;
Hitoshi Kusano;
Koji Nomura;
Steiner, Nancy;
Förster, Irmgard;
Nutt, Stephen L.;
Olshansky, Moshe;
Turner, Stephen J.;
Hamilton, John A.

Publication type:

journal article

Recurrent EZH1 mutations are a second hit in autonomous thyroid adenomas.

Published in:

2016

By:

Calebiro, Davide;
Grassi, Elisa S.;
Eszlinger, Markus;
Ronchi, Cristina L.;
Godbole, Amod;
Bathon, Kerstin;
Guizzardi, Fabiana;
de Filippis, Tiziana;
Krohn, Knut;
Jaeschke, Holger;
Schwarzmayr, Thomas;
Bircan, Rifat;
Gozu, Hulya Iliksu;
Sancak, Seda;
Niedziela, Marek;
Strom, Tim M.;
Fassnacht, Martin;
Persani, Luca;
Paschke, Ralf

Publication type:

journal article

Posttranscriptional manipulation of TERC reverses molecular hallmarks of telomere disease.

Published in:

2016

By:

Boyraz, Baris;
Moon, Diane H.;
Segal, Matthew;
Muosieyiri, Maud Z.;
Aykanat, Asli;
Tai, Albert K.;
Cahan, Patrick;
Agarwal, Suneet

Publication type:

journal article

Calpain-6 confers atherogenicity to macrophages by dysregulating pre-mRNA splicing.

Published in:

2016

By:

Takuro Miyazaki;
Kazuo Tonami;
Shoji Hata;
Toshihiro Aiuchi;
Koji Ohnishi;
Xiao-Feng Lei;
Joo-ri Kim-Kaneyama;
Motohiro Takeya;
Hiroyuki Itabe;
Hiroyuki Sorimachi;
Hiroki Kurihara;
Akira Miyazaki;
Miyazaki, Takuro;
Tonami, Kazuo;
Hata, Shoji;
Aiuchi, Toshihiro;
Ohnishi, Koji;
Lei, Xiao-Feng;
Kim-Kaneyama, Joo-Ri;
Takeya, Motohiro

Publication type:

journal article

Rationally designed BCL6 inhibitors target activated B cell diffuse large B cell lymphoma.

Published in:

2016

By:

Cardenas, Mariano G.;
Wenbo Yu;
Beguelin, Wendy;
Teater, Matthew R.;
Huimin Geng;
Goldstein, Rebecca L.;
Oswald, Erin;
Hatzi, Katerina;
Shao-Ning Yang;
Cohen, Joanna;
Shaknovich, Rita;
Vanommeslaeghe, Kenno;
Huimin Cheng;
Dongdong Liang;
Hyo Je Cho;
Abbott, Joshua;
Tam, Wayne;
Wei Du;
Leonard, John P.;
Elemento, Olivier

Publication type:

journal article

Local TNF causes NFATc1-dependent cholesterol-mediated podocyte injury.

Published in:

2016

By:

Pedigo, Christopher E.;
Ducasa, Gloria Michelle;
Leclercq, Farah;
Sloan, Alexis;
Mitrofanova, Alla;
Hashmi, Tahreem;
Molina-David, Judith;
Ge, Mengyuan;
Lassenius, Mariann I.;
Forsblom, Carol;
Lehto, Markku;
Groop, Per-Henrik;
Kretzler, Matthias;
Eddy, Sean;
Martini, Sebastian;
Reich, Heather;
Wahl, Patricia;
Ghiggeri, GianMarco;
Faul, Christian;
Burke III, George W.

Publication type:

journal article

Vascular stiffness mechanoactivates YAP/TAZ-dependent glutaminolysis to drive pulmonary hypertension.

Published in:

2016

By:

Bertero, Thomas;
Oldham, William M.;
Cottrill, Katherine A.;
Pisano, Sabrina;
Vanderpool, Rebecca R.;
Qiujun Yu;
Jingsi Zhao;
Yiyin Tai;
Ying Tang;
Ying-Yi Zhang;
Rehman, Sofiya;
Masataka Sugahara;
Zhi Qi;
Gorcsan III, John;
Vargas, Sara O.;
Saggar, Rajan;
Saggar, Rajeev;
Wallace, W. Dean;
Ross, David J.;
Haley, Kathleen J.

Publication type:

journal article

EGFR regulates macrophage activation and function in bacterial infection.

Published in:

2016

By:

Hardbower, Dana M.;
Singh, Kshipra;
Asim, Mohammad;
Verriere, Thomas G.;
Olivares-Villagómez, Danyvid;
Barry, Daniel P.;
Allaman, Margaret M.;
Washington, M. Kay;
Peek Jr., Richard M.;
Piazuelo, M. Blanca;
Wilson, Keith T.;
Peek, Richard M Jr

Publication type:

journal article

Lung-resident eosinophils represent a distinct regulatory eosinophil subset.

Published in:

2016

By:

Mesnil, Claire;
Raulier, Stéfanie;
Paulissen, Geneviève;
Xue Xiao;
Birrell, Mark A.;
Pirottin, Dimitri;
Janss, Thibaut;
Starkl, Philipp;
Ramery, Eve;
Henket, Monique;
Schleich, Florence N.;
Radermecker, Marc;
Thielemans, Kris;
Gillet, Laurent;
Thiry, Marc;
Belvisi, Maria G.;
Louis, Renaud;
Desmet, Christophe;
Marichal, Thomas;
Bureau, Fabrice

Publication type:

journal article

A liver stress-endocrine nexus promotes metabolic integrity during dietary protein dilution.

Published in:

2016

By:

Maida, Adriano;
Zota, Annika;
Sjøberg, Kim A.;
Schumacher, Jonas;
Sijmonsma, Tjeerd P.;
Pfenninger, Anja;
Christensen, Marie M.;
Gantert, Thomas;
Fuhrmeister, Jessica;
Rothermel, Ulrike;
Schmoll, Dieter;
Heikenwälder, Mathias;
Iovanna, Juan L.;
Stemmer, Kerstin;
Kiens, Bente;
Herzig, Stephan;
Rose, Adam J.

Publication type:

journal article

BRPF1 is essential for development of fetal hematopoietic stem cells.

Published in:

2016

By:

Linya You;
Lin Li;
Jinfeng Zou;
Kezhi Yan;
Belle, Jad;
Nijnik, Anastasia;
Wang, Edwin;
Xiang-Jiao Yang;
You, Linya;
Li, Lin;
Zou, Jinfeng;
Yan, Kezhi;
Yang, Xiang-Jiao

Publication type:

journal article

Loss of ABCG1 influences regulatory T cell differentiation and atherosclerosis.

Published in:

2016

By:

Hsin-Yuan Cheng;
Gaddis, Dalia E.;
Runpei Wu;
McSkimming, Chantel;
Haynes, LaTeira D.;
Taylor, Angela M.;
McNamara, Coleen A.;
Sorci-Thomas, Mary;
Hedrick, Catherine C.;
Cheng, Hsin-Yuan;
Wu, Runpei

Publication type:

journal article

ZEB1 drives epithelial-to-mesenchymal transition in lung cancer.

Published in:

2016

By:

Larsen, Jill E.;
Nathan, Vaishnavi;
Osborne, Jihan K.;
Farrow, Rebecca K.;
Deb, Dhruba;
Sullivan, James P.;
Dospoy, Patrick D.;
Augustyn, Alexander;
Hight, Suzie K.;
Sato, Mitsuo;
Girard, Luc;
Behrens, Carmen;
Wistuba, Ignacio I.;
Gazdar, Adi F.;
Hayward, Nicholas K.;
Minna, John D.

Publication type:

journal article

Dasatinib induces lung vascular toxicity and predisposes to pulmonary hypertension.

Published in:

2016

By:

Guignabert, Christophe;
Phan, Carole;
Seferian, Andrei;
Huertas, Alice;
Ly Tu;
Thuillet, Raphaël;
Sattler, Caroline;
Le Hiress, Morane;
Yuichi Tamura;
Jutant, Etienne-Marie;
Chaumais, Marie-Camille;
Bouchet, Stéphane;
Manéglier, Benjamin;
Molimard, Mathieu;
Rousselot, Philippe;
Sitbon, Olivier;
Simonneau, Gérald;
Montani, David;
Humbert, Marc;
Tu, Ly

Publication type:

journal article

A tribute to Philip W. Majerus.

Published in:

2016

By:

York, John D.;
Vagelos, P. Roy

Publication type:

journal article

Tie1: an orphan receptor provides context for angiopoietin-2/Tie2 signaling.

Published in:

2016

By:

Mueller, Sarah B.;
Kontos, Christopher D.

Publication type:

journal article

A hidden residential cell in the lung.

Published in:

2016

By:

Rothenberg, Marc E.

Publication type:

journal article

Bioactive extracellular matrix fragments in lung health and disease.

Published in:

2016

By:

Gaggar, Amit;
Weathington, Nathaniel

Publication type:

journal article

Kaposi sarcoma-associated herpesvirus: immunobiology, oncogenesis, and therapy.

Published in:

2016

By:

Dittmer, Dirk P.;
Damania, Blossom

Publication type:

journal article

Disruption of Gpr45 causes reduced hypothalamic POMC expression and obesity.

Published in:

2016

By:

Jing Cui;
Yi Ding;
Shu Chen;
Xiaoqiang Zhu;
Yichen Wu;
Mingliang Zhang;
Yaxin Zhao;
Li, Tong-Ruei R.;
Sun, Ling V.;
Shimin Zhao;
Yuan Zhuang;
Weiping Jia;
Lei Xue;
Min Han;
Tian Xu;
Xiaohui Wu;
Cui, Jing;
Ding, Yi;
Chen, Shu;
Zhu, Xiaoqiang

Publication type:

journal article

A conversation with Alexander Rudensky.

Published in:

2016

By:

Neill, Ushma S.

Publication type:

Biography