Works matching IS 00219738 AND DT 2016 AND VI 126 AND IP 9

Results: 40

Transcription factor TBX4 regulates myofibroblast accumulation and lung fibrosis.
Published in:
2016
By:
- Xie, Ting;
- Liang, Jiurong;
- Liu, Ningshan;
- Huan, Caijuan;
- Zhang, Yanli;
- Liu, Weijia;
- Kumar, Maya;
- Xiao, Rui;
- D'Armiento, Jeanine;
- Metzger, Daniel;
- Chambon, Pierre;
- Papaioannou, Virginia E;
- Stripp, Barry R;
- Jiang, Dianhua;
- Noble, Paul W
Publication type:
journal article
Hotspot autoimmune T cell receptor binding underlies pathogen and insulin peptide cross-reactivity.
Published in:
2016
By:
- Cole, David K;
- Bulek, Anna M;
- Dolton, Garry;
- Schauenberg, Andrea J;
- Szomolay, Barbara;
- Rittase, William;
- Trimby, Andrew;
- Jothikumar, Prithiviraj;
- Fuller, Anna;
- Skowera, Ania;
- Rossjohn, Jamie;
- Zhu, Cheng;
- Miles, John J;
- Peakman, Mark;
- Wooldridge, Linda;
- Rizkallah, Pierre J;
- Sewell, Andrew K
Publication type:
journal article
PIK3C2B inhibition improves function and prolongs survival in myotubular myopathy animal models.
Published in:
2016
By:
- Sabha, Nesrin;
- Volpatti, Jonathan R.;
- Gonorazky, Hernan;
- Reifler, Aaron;
- Davidson, Ann E.;
- Xingli Li;
- Eltayeb, Nadine M.;
- Dall'Armi, Claudia;
- Di Paolo, Gilbert;
- Brooks, Susan V.;
- Buj-Bello, Ana;
- Feldman, Eva L.;
- Dowling, James J.;
- Li, Xingli
Publication type:
journal article
Urea impairs β cell glycolysis and insulin secretion in chronic kidney disease.
Published in:
2016
By:
- Koppe, Laetitia;
- Nyam, Elsa;
- Vivot, Kevin;
- Manning Fox, Jocelyn E.;
- Xiao-Qing Dai;
- Nguyen, Bich N.;
- Trudel, Dominique;
- Attané, Camille;
- Moullé, Valentine S.;
- MacDonald, Patrick E.;
- Ghislain, Julien;
- Poitout, Vincent;
- Dai, Xiao-Qing
Publication type:
journal article
Serine 421 regulates mutant huntingtin toxicity and clearance in mice.
Published in:
2016
By:
- Kratter, Ian H.;
- Zahed, Hengameh;
- Lau, Alice;
- Tsvetkov, Andrey S.;
- Daub, Aaron C.;
- Weiberth, Kurt F.;
- Xiaofeng Gu;
- Saudou, Frédéric;
- Humbert, Sandrine;
- Yang, X. William;
- Osmand, Alex;
- Steffan, Joan S.;
- Masliah, Eliezer;
- Finkbeiner, Steven;
- Gu, Xiaofeng
Publication type:
journal article
Biallelic inactivation of REV7 is associated with Fanconi anemia.
Published in:
2016
By:
- Bluteau, Dominique;
- Masliah-Planchon, Julien;
- Clairmont, Connor;
- Rousseau, Alix;
- Ceccaldi, Raphael;
- Dubois d'Enghien, Catherine;
- Bluteau, Olivier;
- Cuccuini, Wendy;
- Gachet, Stéphanie;
- de Latour, Régis Peffault;
- Leblanc, Thierry;
- Socié, Gérard;
- Baruchel, André;
- Stoppa-Lyonnet, Dominique;
- D'Andrea, Alan D.;
- Soulier, Jean;
- Peffault de Latour, Régis
Publication type:
journal article
MondoA coordinately regulates skeletal myocyte lipid homeostasis and insulin signaling.
Published in:
2016
By:
- Byungyong Ahn;
- Soundarapandian, Mangala M.;
- Sessions, Hampton;
- Peddibhotla, Satyamaheshwar;
- Roth, Gregory P.;
- Jian-Liang Li;
- Sugarman, Eliot;
- Koo, Ada;
- Malany, Siobhan;
- Miao Wang;
- Kyungmoo Yea;
- Brooks, Jeanne;
- Leone, Teresa C.;
- Xianlin Han;
- Vega, Rick B.;
- Kelly, Daniel P.;
- Ahn, Byungyong;
- Li, Jian-Liang;
- Wang, Miao;
- Yea, Kyungmoo
Publication type:
journal article
Mitochondrial calcium uptake underlies ROS generation during aminoglycoside-induced hair cell death.
Published in:
2016
By:
- Esterberg, Robert;
- Linbo, Tor;
- Pickett, Sarah B.;
- Wu, Patricia;
- Ou, Henry C.;
- Rubel, Edwin W.;
- Raible, David W.
Publication type:
journal article
A colitogenic memory CD4+ T cell population mediates gastrointestinal graft-versus-host disease.
Published in:
2016
By:
- Zhou, Vivian;
- Agle, Kimberle;
- Xiao Chen;
- Beres, Amy;
- Komorowski, Richard;
- Belle, Ludovic;
- Taylor, Carolyn;
- Fenlu Zhu;
- Haribhai, Dipica;
- Williams, Calvin B.;
- Verbsky, James;
- Blumenschein, Wendy;
- Sadekova, Svetlana;
- Bowman, Eddie;
- Ballantyne, Christie;
- Weaver, Casey;
- Serody, David A.;
- Vincent, Benjamin;
- Serody, Jonathan;
- Cua, Daniel J.
Publication type:
journal article
Mechanistically distinct cancer-associated mTOR activation clusters predict sensitivity to rapamycin.
Published in:
2016
By:
- Jianing Xu;
- Pham, Can G.;
- Albanese, Steven K.;
- Yiyu Dong;
- Toshinao Oyama;
- Chung-Han Lee;
- Rodrik-Outmezguine, Vanessa;
- Zhan Yao;
- Song Han;
- Chen, David;
- Parton, Daniel L.;
- Chodera, John D.;
- Rosen, Neal;
- Cheng, Emily H.;
- Hsieh, James J.;
- Xu, Jianing;
- Dong, Yiyu;
- Oyama, Toshinao;
- Lee, Chung-Han;
- Yao, Zhan
Publication type:
journal article
Opposing actions of angiopoietin-2 on Tie2 signaling and FOXO1 activation.
Published in:
2016
By:
- Kim, Minah;
- Allen, Breanna;
- Korhonen, Emilia A.;
- Nitschké, Maximilian;
- Hee Won Yang;
- Baluk, Peter;
- Saharinen, Pipsa;
- Alitalo, Kari;
- Daly, Christopher;
- Thurston, Gavin;
- McDonald, Donald M.;
- Yang, Hee Won
Publication type:
journal article
Tie1 controls angiopoietin function in vascular remodeling and inflammation.
Published in:
2016
By:
- Korhonen, Emilia A.;
- Lampinen, Anita;
- Giri, Hemant;
- Anisimov, Andrey;
- Kim, Minah;
- Allen, Breanna;
- Shentong Fang;
- D'Amico, Gabriela;
- Sipilä, Tuomas J.;
- Lohela, Marja;
- Strandin, Tomas;
- Vaheri, Antti;
- Ylä-Herttuala, Seppo;
- Gou Young Koh;
- McDonald, Donald M.;
- Alitalo, Kari;
- Saharinen, Pipsa;
- Fang, Shentong;
- Koh, Gou Young
Publication type:
journal article
BET bromodomain inhibition enhances T cell persistence and function in adoptive immunotherapy models.
Published in:
2016
By:
- Yuki Kagoya;
- Munehide Nakatsugawa;
- Yuki Yamashita;
- Toshiki Ochi;
- Tingxi Guo;
- Anczurowski, Mark;
- Kayoko Saso;
- Butler, Marcus O.;
- Arrowsmith, Cheryl H.;
- Naoto Hirano;
- Kagoya, Yuki;
- Nakatsugawa, Munehide;
- Yamashita, Yuki;
- Ochi, Toshiki;
- Guo, Tingxi;
- Saso, Kayoko;
- Hirano, Naoto
Publication type:
journal article
Vascular stiffness mechanoactivates YAP/TAZ-dependent glutaminolysis to drive pulmonary hypertension.
Published in:
2016
By:
- Bertero, Thomas;
- Oldham, William M.;
- Cottrill, Katherine A.;
- Pisano, Sabrina;
- Vanderpool, Rebecca R.;
- Qiujun Yu;
- Jingsi Zhao;
- Yiyin Tai;
- Ying Tang;
- Ying-Yi Zhang;
- Rehman, Sofiya;
- Masataka Sugahara;
- Zhi Qi;
- Gorcsan III, John;
- Vargas, Sara O.;
- Saggar, Rajan;
- Saggar, Rajeev;
- Wallace, W. Dean;
- Ross, David J.;
- Haley, Kathleen J.
Publication type:
journal article
β1-Adrenergic receptor deficiency in ghrelin-expressing cells causes hypoglycemia in susceptible individuals.
Published in:
2016
By:
- Mani, Bharath K.;
- Osborne-Lawrence, Sherri;
- Vijayaraghavan, Prasanna;
- Hepler, Chelsea;
- Zigman, Jeffrey M.
Publication type:
journal article
Tumor immune profiling predicts response to anti-PD-1 therapy in human melanoma.
Published in:
2016
By:
- Daud, Adil I.;
- Loo, Kimberly;
- Pauli, Mariela L.;
- Sanchez-Rodriguez, Robert;
- Munoz Sandoval, Priscila;
- Taravati, Keyon;
- Tsai, Katy;
- Nosrati, Adi;
- Nardo, Lorenzo;
- Alvarado, Michael D.;
- Algazi, Alain P.;
- Pampaloni, Miguel H.;
- Lobach, Iryna V.;
- Hwang, Jimmy;
- Pierce, Robert H.;
- Gratz, Iris K.;
- Krummel, Matthew F.;
- Rosenblum, Michael D.;
- Sandoval, Priscila Munoz
Publication type:
journal article
Insulin and IGF-1 receptors regulate FoxO-mediated signaling in muscle proteostasis.
Published in:
2016
By:
- O'Neill, Brian T.;
- Lee, Kevin Y.;
- Klaus, Katherine;
- Softic, Samir;
- Krumpoch, Megan T.;
- Fentz, Joachim;
- Stanford, Kristin I.;
- Robinson, Matthew M.;
- Weikang Cai;
- Kleinridders, Andre;
- Pereira, Renata O.;
- Hirshman, Michael F.;
- Abel, E. Dale;
- Accili, Domenico;
- Goodyear, Laurie J.;
- Nair, K. Sreekumaran;
- Kahn, C. Ronald;
- Cai, Weikang
Publication type:
journal article
Calpain-6 confers atherogenicity to macrophages by dysregulating pre-mRNA splicing.
Published in:
2016
By:
- Takuro Miyazaki;
- Kazuo Tonami;
- Shoji Hata;
- Toshihiro Aiuchi;
- Koji Ohnishi;
- Xiao-Feng Lei;
- Joo-ri Kim-Kaneyama;
- Motohiro Takeya;
- Hiroyuki Itabe;
- Hiroyuki Sorimachi;
- Hiroki Kurihara;
- Akira Miyazaki;
- Miyazaki, Takuro;
- Tonami, Kazuo;
- Hata, Shoji;
- Aiuchi, Toshihiro;
- Ohnishi, Koji;
- Lei, Xiao-Feng;
- Kim-Kaneyama, Joo-Ri;
- Takeya, Motohiro
Publication type:
journal article
Tyrosine kinase FYN negatively regulates NOX4 in cardiac remodeling.
Published in:
2016
By:
- Shouji Matsushima;
- Junya Kuroda;
- Peiyong Zhai;
- Tong Liu;
- Shohei Ikeda;
- Narayani Nagarajan;
- Shin-ichi Oka;
- Takashi Yokota;
- Shintaro Kinugawa;
- Chiao-Po Hsu;
- Hong Li;
- Hiroyuki Tsutsui;
- Junichi Sadoshima;
- Matsushima, Shouji;
- Kuroda, Junya;
- Zhai, Peiyong;
- Liu, Tong;
- Ikeda, Shohei;
- Nagarajan, Narayani;
- Oka, Shin-Ichi
Publication type:
journal article
Granulocyte macrophage colony-stimulating factor induces CCL17 production via IRF4 to mediate inflammation.
Published in:
2016
By:
- Achuthan, Adrian;
- Cook, Andrew D.;
- Ming-Chin Lee;
- Saleh, Reem;
- Hsu-Wei Khiew;
- Chang, Melody W. N.;
- Louis, Cynthia;
- Fleetwood, Andrew J.;
- Lacey, Derek C.;
- Christensen, Anne D.;
- Frye, Ashlee T.;
- Pui Yeng Lam;
- Hitoshi Kusano;
- Koji Nomura;
- Steiner, Nancy;
- Förster, Irmgard;
- Nutt, Stephen L.;
- Olshansky, Moshe;
- Turner, Stephen J.;
- Hamilton, John A.
Publication type:
journal article
Lymphatic vessels regulate immune microenvironments in human and murine melanoma.
Published in:
2016
By:
- Lund, Amanda W.;
- Wagner, Marek;
- Fankhauser, Manuel;
- Steinskog, Eli S.;
- Broggi, Maria A.;
- Spranger, Stefani;
- Gajewski, Thomas F.;
- Alitalo, Kari;
- Eikesdal, Hans P.;
- Wiig, Helge;
- Swartz, Melody A.
Publication type:
journal article
Posttranscriptional manipulation of TERC reverses molecular hallmarks of telomere disease.
Published in:
2016
By:
- Boyraz, Baris;
- Moon, Diane H.;
- Segal, Matthew;
- Muosieyiri, Maud Z.;
- Aykanat, Asli;
- Tai, Albert K.;
- Cahan, Patrick;
- Agarwal, Suneet
Publication type:
journal article
Phase I trials using Sleeping Beauty to generate CD19-specific CAR T cells.
Published in:
2016
By:
- Kebriaei, Partow;
- Singh, Harjeet;
- Huls, M. Helen;
- Figliola, Matthew J.;
- Bassett, Roland;
- Olivares, Simon;
- Jena, Bipulendu;
- Dawson, Margaret J.;
- Kumaresan, Pappanaicken R.;
- Shihuang Su;
- Maiti, Sourindra;
- Jianliang Dai;
- Moriarity, Branden;
- Forget, Marie-Andrée;
- Senyukov, Vladimir;
- Orozco, Aaron;
- Tingting Liu;
- McCarty, Jessica;
- Jackson, Rineka N.;
- Moyes, Judy S.
Publication type:
journal article
Local TNF causes NFATc1-dependent cholesterol-mediated podocyte injury.
Published in:
2016
By:
- Pedigo, Christopher E.;
- Ducasa, Gloria Michelle;
- Leclercq, Farah;
- Sloan, Alexis;
- Mitrofanova, Alla;
- Hashmi, Tahreem;
- Molina-David, Judith;
- Ge, Mengyuan;
- Lassenius, Mariann I.;
- Forsblom, Carol;
- Lehto, Markku;
- Groop, Per-Henrik;
- Kretzler, Matthias;
- Eddy, Sean;
- Martini, Sebastian;
- Reich, Heather;
- Wahl, Patricia;
- Ghiggeri, GianMarco;
- Faul, Christian;
- Burke III, George W.
Publication type:
journal article
Rationally designed BCL6 inhibitors target activated B cell diffuse large B cell lymphoma.
Published in:
2016
By:
- Cardenas, Mariano G.;
- Wenbo Yu;
- Beguelin, Wendy;
- Teater, Matthew R.;
- Huimin Geng;
- Goldstein, Rebecca L.;
- Oswald, Erin;
- Hatzi, Katerina;
- Shao-Ning Yang;
- Cohen, Joanna;
- Shaknovich, Rita;
- Vanommeslaeghe, Kenno;
- Huimin Cheng;
- Dongdong Liang;
- Hyo Je Cho;
- Abbott, Joshua;
- Tam, Wayne;
- Wei Du;
- Leonard, John P.;
- Elemento, Olivier
Publication type:
journal article
Recurrent EZH1 mutations are a second hit in autonomous thyroid adenomas.
Published in:
2016
By:
- Calebiro, Davide;
- Grassi, Elisa S.;
- Eszlinger, Markus;
- Ronchi, Cristina L.;
- Godbole, Amod;
- Bathon, Kerstin;
- Guizzardi, Fabiana;
- de Filippis, Tiziana;
- Krohn, Knut;
- Jaeschke, Holger;
- Schwarzmayr, Thomas;
- Bircan, Rifat;
- Gozu, Hulya Iliksu;
- Sancak, Seda;
- Niedziela, Marek;
- Strom, Tim M.;
- Fassnacht, Martin;
- Persani, Luca;
- Paschke, Ralf
Publication type:
journal article
EGFR regulates macrophage activation and function in bacterial infection.
Published in:
2016
By:
- Hardbower, Dana M.;
- Singh, Kshipra;
- Asim, Mohammad;
- Verriere, Thomas G.;
- Olivares-Villagómez, Danyvid;
- Barry, Daniel P.;
- Allaman, Margaret M.;
- Washington, M. Kay;
- Peek Jr., Richard M.;
- Piazuelo, M. Blanca;
- Wilson, Keith T.;
- Peek, Richard M Jr
Publication type:
journal article
Lung-resident eosinophils represent a distinct regulatory eosinophil subset.
Published in:
2016
By:
- Mesnil, Claire;
- Raulier, Stéfanie;
- Paulissen, Geneviève;
- Xue Xiao;
- Birrell, Mark A.;
- Pirottin, Dimitri;
- Janss, Thibaut;
- Starkl, Philipp;
- Ramery, Eve;
- Henket, Monique;
- Schleich, Florence N.;
- Radermecker, Marc;
- Thielemans, Kris;
- Gillet, Laurent;
- Thiry, Marc;
- Belvisi, Maria G.;
- Louis, Renaud;
- Desmet, Christophe;
- Marichal, Thomas;
- Bureau, Fabrice
Publication type:
journal article
A liver stress-endocrine nexus promotes metabolic integrity during dietary protein dilution.
Published in:
2016
By:
- Maida, Adriano;
- Zota, Annika;
- Sjøberg, Kim A.;
- Schumacher, Jonas;
- Sijmonsma, Tjeerd P.;
- Pfenninger, Anja;
- Christensen, Marie M.;
- Gantert, Thomas;
- Fuhrmeister, Jessica;
- Rothermel, Ulrike;
- Schmoll, Dieter;
- Heikenwälder, Mathias;
- Iovanna, Juan L.;
- Stemmer, Kerstin;
- Kiens, Bente;
- Herzig, Stephan;
- Rose, Adam J.
Publication type:
journal article
BRPF1 is essential for development of fetal hematopoietic stem cells.
Published in:
2016
By:
- Linya You;
- Lin Li;
- Jinfeng Zou;
- Kezhi Yan;
- Belle, Jad;
- Nijnik, Anastasia;
- Wang, Edwin;
- Xiang-Jiao Yang;
- You, Linya;
- Li, Lin;
- Zou, Jinfeng;
- Yan, Kezhi;
- Yang, Xiang-Jiao
Publication type:
journal article
Loss of ABCG1 influences regulatory T cell differentiation and atherosclerosis.
Published in:
2016
By:
- Hsin-Yuan Cheng;
- Gaddis, Dalia E.;
- Runpei Wu;
- McSkimming, Chantel;
- Haynes, LaTeira D.;
- Taylor, Angela M.;
- McNamara, Coleen A.;
- Sorci-Thomas, Mary;
- Hedrick, Catherine C.;
- Cheng, Hsin-Yuan;
- Wu, Runpei
Publication type:
journal article
ZEB1 drives epithelial-to-mesenchymal transition in lung cancer.
Published in:
2016
By:
- Larsen, Jill E.;
- Nathan, Vaishnavi;
- Osborne, Jihan K.;
- Farrow, Rebecca K.;
- Deb, Dhruba;
- Sullivan, James P.;
- Dospoy, Patrick D.;
- Augustyn, Alexander;
- Hight, Suzie K.;
- Sato, Mitsuo;
- Girard, Luc;
- Behrens, Carmen;
- Wistuba, Ignacio I.;
- Gazdar, Adi F.;
- Hayward, Nicholas K.;
- Minna, John D.
Publication type:
journal article
Dasatinib induces lung vascular toxicity and predisposes to pulmonary hypertension.
Published in:
2016
By:
- Guignabert, Christophe;
- Phan, Carole;
- Seferian, Andrei;
- Huertas, Alice;
- Ly Tu;
- Thuillet, Raphaël;
- Sattler, Caroline;
- Le Hiress, Morane;
- Yuichi Tamura;
- Jutant, Etienne-Marie;
- Chaumais, Marie-Camille;
- Bouchet, Stéphane;
- Manéglier, Benjamin;
- Molimard, Mathieu;
- Rousselot, Philippe;
- Sitbon, Olivier;
- Simonneau, Gérald;
- Montani, David;
- Humbert, Marc;
- Tu, Ly
Publication type:
journal article
Disruption of Gpr45 causes reduced hypothalamic POMC expression and obesity.
Published in:
2016
By:
- Jing Cui;
- Yi Ding;
- Shu Chen;
- Xiaoqiang Zhu;
- Yichen Wu;
- Mingliang Zhang;
- Yaxin Zhao;
- Li, Tong-Ruei R.;
- Sun, Ling V.;
- Shimin Zhao;
- Yuan Zhuang;
- Weiping Jia;
- Lei Xue;
- Min Han;
- Tian Xu;
- Xiaohui Wu;
- Cui, Jing;
- Ding, Yi;
- Chen, Shu;
- Zhu, Xiaoqiang
Publication type:
journal article
Tie1: an orphan receptor provides context for angiopoietin-2/Tie2 signaling.
Published in:
2016
By:
- Mueller, Sarah B.;
- Kontos, Christopher D.
Publication type:
journal article
A hidden residential cell in the lung.
Published in:
2016
By:
- Rothenberg, Marc E.
Publication type:
journal article
Bioactive extracellular matrix fragments in lung health and disease.
Published in:
2016
By:
- Gaggar, Amit;
- Weathington, Nathaniel
Publication type:
journal article
Kaposi sarcoma-associated herpesvirus: immunobiology, oncogenesis, and therapy.
Published in:
2016
By:
- Dittmer, Dirk P.;
- Damania, Blossom
Publication type:
journal article
A tribute to Philip W. Majerus.
Published in:
2016
By:
- York, John D.;
- Vagelos, P. Roy
Publication type:
journal article
A conversation with Alexander Rudensky.
Published in:
2016
By:
- Neill, Ushma S.
Publication type:
Biography