Search Results | Scholarly Articles, Journals, and E-Books

Results: 43

Proximity ligation assay evaluates IDH1R132H presentation in gliomas.
Published in:
2015
By:
- Bunse, Lukas;
- Schumacher, Theresa;
- Sahm, Felix;
- Pusch, Stefan;
- Oezen, Iris;
- Rauschenbach, Katharina;
- Gonzalez, Marina;
- Solecki, Gergely;
- Osswald, Matthias;
- Capper, David;
- Wiestler, Benedikt;
- Winkler, Frank;
- Herold-Mende, Christel;
- von Deimling, Andreas;
- Wick, Wolfgang;
- Platten, Michael
Publication type:
journal article
Corrigendum.
Published in:
2015
Publication type:
Correction Notice
A conversation with James Rothman.
Published in:
2015
By:
- Neill, Ushma S.
Publication type:
Interview
Targeting the extrinsic apoptotic pathway in cancer: lessons learned and future directions.
Published in:
Journal of Clinical Investigation, 2015, v. 125, n. 2, p. 487, doi. 10.1172/JCI80420
By:
- Ashkenazi, Avi
Publication type:
Article
The importance of being transparent.
Published in:
Journal of Clinical Investigation, 2015, v. 125, n. 2, p. 459, doi. 10.1172/JCI80370
By:
- Jackson, Sarah
Publication type:
Article
Role reversal: infiltrating T cells protect the brain.
Published in:
Journal of Clinical Investigation, 2015, v. 125, n. 2, p. 493, doi. 10.1172/JCI80279
By:
- Steinman, Lawrence
Publication type:
Article
Fighting polyglutamine disease by wrestling with SUMO.
Published in:
Journal of Clinical Investigation, 2015, v. 125, n. 2, p. 498, doi. 10.1172/JCI80278
By:
- Craig, Tim J.;
- Henley, Jeremy M.
Publication type:
Article
Corrigendum.
Published in:
2015
Publication type:
Correction Notice
CRALBP supports the mammalian retinal visual cycle and cone vision.
Published in:
Journal of Clinical Investigation, 2015, v. 125, n. 2, p. 727, doi. 10.1172/JCI79651
By:
- Yunlu Xue;
- Shen, Susan Q.;
- Jui, Jonathan;
- Rupp, Alan C.;
- Byrne, Leah C.;
- Hattar, Samer;
- Flannery, John G.;
- Corbo, Joseph C.;
- Kefalov, Vladimir J.
Publication type:
Article
Differentiation of hypothalamic-like neurons from human pluripotent stem cells.
Published in:
Journal of Clinical Investigation, 2015, v. 125, n. 2, p. 796, doi. 10.1172/JCI79220
By:
- Liheng Wang;
- Meece, Kana;
- Williams, Damian J.;
- Kinyui Alice Lo;
- Zimmer, Matthew;
- Heinrich, Garrett;
- Carli, Jayne Martin;
- Leduc, Charles A.;
- Sun, Lei;
- Zeltser, Lori M.;
- Freeby, Matthew;
- Goland, Robin;
- Tsang, Stephen H.;
- Wardlaw, Sharon L.;
- Egli, Dieter;
- Leibel, Rudolph L.
Publication type:
Article
Vector design influences hepatic genotoxicity after adeno-associated virus gene therapy.
Published in:
Journal of Clinical Investigation, 2015, v. 125, n. 2, p. 870, doi. 10.1172/JCI79213
By:
- Chandler, Randy J.;
- LaFave, Matthew C.;
- Varshney, Gaurav K.;
- Trivedi, Niraj S.;
- Carrillo-Carrasco, Nuria;
- Senac, Julien S.;
- Weiwei Wu;
- Hoffmann, Victoria;
- Elkahloun, Abdel G.;
- Burgess, Shawn M.;
- Venditti, Charles P.
Publication type:
Article
In vivo analysis of lung cancer metabolism: nothing like the real thing.
Published in:
Journal of Clinical Investigation, 2015, v. 125, n. 2, p. 495, doi. 10.1172/JCI79188
By:
- Hensley, Christopher T.;
- DeBerardinis, Ralph J.
Publication type:
Article
Ghrelin and hypothalamic development: too little and too much of a good thing.
Published in:
Journal of Clinical Investigation, 2015, v. 125, n. 2, p. 490, doi. 10.1172/JCI79187
By:
- Tong, Jenny;
- D'Alessio, David
Publication type:
Article
GP96 is a GARP chaperone and controls regulatory T cell functions.
Published in:
Journal of Clinical Investigation, 2015, v. 125, n. 2, p. 859, doi. 10.1172/JCI79014
By:
- Yongliang Zhang;
- Wu, Bill X.;
- Metelli, Alessandra;
- Thaxton, Jessica E.;
- Feng Hong;
- Rachidi, Saleh;
- Ansa-Addo, Ephraim;
- Shaoli Sun;
- Vasu, Chenthamarakshan;
- Yi Yang;
- Bei Liu;
- Zihai Li
Publication type:
Article
F-box protein FBXW7 inhibits cancer metastasis in a non-cell-autonomous manner.
Published in:
Journal of Clinical Investigation, 2015, v. 125, n. 2, p. 621, doi. 10.1172/JCI78782
By:
- Kanae Yumimoto;
- Sayuri Akiyoshi;
- Hiroki Ueo;
- Yasuaki Sagara;
- Ichiro Onoyama;
- Hiroaki Ueo;
- Shinji Ohno;
- Masaki Mori;
- Koshi Mimori;
- Keiichi I. Nakayama
Publication type:
Article
Telomerase mutations in smokers with severe emphysema.
Published in:
Journal of Clinical Investigation, 2015, v. 125, n. 2, p. 563, doi. 10.1172/JCI78554
By:
- Stanley, Susan E.;
- Chen, Julian J. L.;
- Podlevsky, Joshua D.;
- Alder, Jonathan K.;
- Hansel, Nadia N.;
- Mathias, Rasika A.;
- Xiaodong Qi;
- Rafaels, Nicholas M.;
- Wise, Robert A.;
- Silverman, Edwin K.;
- Barnes, Kathleen C.;
- Armanios, Mary
Publication type:
Article
Increased glutamine catabolism mediates bone anabolism in response to WNT signaling.
Published in:
Journal of Clinical Investigation, 2015, v. 125, n. 2, p. 551, doi. 10.1172/JCI78470
By:
- Karner, Courtney M.;
- Esen, Emel;
- Okunade, Adewole L.;
- Patterson, Bruce W.;
- Long, Fanxin
Publication type:
Article
Metabolically normal obese people are protected from adverse effects following weight gain.
Published in:
Journal of Clinical Investigation, 2015, v. 125, n. 2, p. 787, doi. 10.1172/JCI78425
By:
- Fabbrini, Elisa;
- Yoshino, Jun;
- Mihoko Yoshino;
- Magkos, Faidon;
- Tiemann Luecking, Courtney;
- Samovski, Dmitri;
- Fraterrigo, Gemma;
- Okunade, Adewole L.;
- Patterson, Bruce W.;
- Klein, Samuel
Publication type:
Article
Dysregulation of microRNA-219 promotes neurodegeneration through post-transcriptional regulation of tau.
Published in:
Journal of Clinical Investigation, 2015, v. 125, n. 2, p. 681, doi. 10.1172/JCI78421
By:
- Santa-Maria, Ismael;
- Alaniz, Maria E.;
- Renwick, Neil;
- Cela, Carolina;
- Fulga, Tudor A.;
- Van Vactor, David;
- Tuschl, Thomas;
- Clark, Lorraine N.;
- Shelanski, Michael L.;
- McCabe, Brian D.;
- Crary, John F.
Publication type:
Article
Brown and beige fat in humans: thermogenic adipocytes that control energy and glucose homeostasis.
Published in:
Journal of Clinical Investigation, 2015, v. 125, n. 2, p. 478, doi. 10.1172/JCI78362
By:
- Sidossis, Labros;
- Shingo Kajimura
Publication type:
Article
Neuroepithelial circuit formed by innervation of sensory enteroendocrine cells.
Published in:
Journal of Clinical Investigation, 2015, v. 125, n. 2, p. 782, doi. 10.1172/JCI78361
By:
- Bohórquez, Diego V.;
- Shahid, Rafiq A.;
- Erdmann, Alan;
- Kreger, Alex M.;
- Yu Wang;
- Calakos, Nicole;
- Fan Wang;
- Liddle, Rodger A.
Publication type:
Article
UCP2-induced fatty acid synthase promotes NLRP3 inflammasome activation during sepsis.
Published in:
Journal of Clinical Investigation, 2015, v. 125, n. 2, p. 665, doi. 10.1172/JCI78253
By:
- Jong-Seok Moon;
- Seonmin Lee;
- Mi-Ae Park;
- Siempos, Ilias I.;
- Haslip, Maria;
- Lee, Patty J.;
- Mijin Yun;
- Chun K. Kim;
- Howrylak, Judie;
- Ryter, Stefan W.;
- Kiichi Nakahira;
- Choi, Augustine M. K.
Publication type:
Article
NOTCH pathway inactivation promotes bladder cancer progression.
Published in:
Journal of Clinical Investigation, 2015, v. 125, n. 2, p. 824, doi. 10.1172/JCI78185
By:
- Maraver, Antonio;
- Fernandez-Marcos, Pablo J.;
- Cash, Timothy P.;
- Mendez-Pertuz, Marinela;
- Dueñas, Marta;
- Maietta, Paolo;
- Martinelli, Paola;
- Muñoz-Martin, Maribel;
- Martínez-Fernández, Mónica;
- Cañamero, Marta;
- Roncador, Giovanna;
- Martinez-Torrecuadrada, Jorge L.;
- Grivas, Dimitrios;
- de la Pompa, Jose Luis;
- Valencia, Alfonso;
- Paramio, Jesús M.;
- Real, Francisco X.;
- Serrano, Manuel
Publication type:
Article
Proximity ligation assay evaluates IDH1<sup>R132H</sup> presentation in gliomas.
Published in:
Journal of Clinical Investigation, 2015, v. 125, n. 2, p. 593, doi. 10.1172/JCI77780
By:
- Bunse, Lukas;
- Schumacher, Theresa;
- Sahm, Felix;
- Pusch, Stefan;
- Oezen, Iris;
- Rauschenbach, Katharina;
- Gonzalez, Marina;
- Solecki, Gergely;
- Osswald, Matthias;
- Capper, David;
- Wiestler, Benedikt;
- Winkler, Frank;
- Herold-Mende, Christel;
- von Deimling, Andreas;
- Wick, Wolfgang;
- Platten, Michael
Publication type:
Article
Pyruvate carboxylase is critical for non--small-cell lung cancer proliferation.
Published in:
Journal of Clinical Investigation, 2015, v. 125, n. 2, p. 687, doi. 10.1172/JCI72873
By:
- Sellers, Katherine;
- Fox, Matthew P.;
- Bousamra II, Michael;
- Slone, Stephen P.;
- Higashi, Richard M.;
- Miller, Donald M.;
- Yali Wang;
- Yan, Jun;
- Yuneva, Mariia O.;
- Deshpande, Rahul;
- Lane, Andrew N.;
- Fan, Teresa W.-M.
Publication type:
Article
Sirtuin 3--dependent mitochondrial dynamic improvements protect against acute kidney injury.
Published in:
Journal of Clinical Investigation, 2015, v. 125, n. 2, p. 715, doi. 10.1172/JCI77632
By:
- Morigi, Marina;
- Perico, Luca;
- Rota, Cinzia;
- Longaretti, Lorena;
- Conti, Sara;
- Rottoli, Daniela;
- Novelli, Rubina;
- Remuzzi, Giuseppe;
- Benigni, Ariela
Publication type:
Article
Differences in hypothalamic type 2 deiodinase ubiquitination explain localized sensitivity to thyroxine.
Published in:
Journal of Clinical Investigation, 2015, v. 125, n. 2, p. 769, doi. 10.1172/JCI77588
By:
- Werneck de Castro, Joao Pedro;
- Fonseca, Tatiana L.;
- Ueta, Cintia B.;
- McAninch, Elizabeth A.;
- Abdalla, Sherine;
- Wittmann, Gabor;
- Lechan, Ronald M.;
- Gereben, Balazs;
- Bianco, Antonio C.
Publication type:
Article
Global transcriptional disturbances underlie Cornelia de Lange syndrome and related phenotypes.
Published in:
Journal of Clinical Investigation, 2015, v. 125, n. 2, p. 636, doi. 10.1172/JCI77435
By:
- Bo Yuan;
- Pehlivan, Davut;
- Karaca, Ender;
- Patel, Nisha;
- Wu-Lin Charng;
- Gambin, Tomasz;
- Gonzaga-Jauregui, Claudia;
- Sutton, V. Reid;
- Yesil, Gozde;
- Bozdogan, Sevcan Tug;
- Tos, Tulay;
- Koparir, Asuman;
- Koparir, Erkan;
- Beck, Christine R.;
- Shen Gu;
- Aslan, Huseyin;
- Yuregir, Ozge Ozalp;
- Al Rubeaan, Khalid;
- Alnaqeb, Dhekra;
- Alshammari, Muneera J.
Publication type:
Article
Neonatal ghrelin programs development of hypothalamic feeding circuits.
Published in:
Journal of Clinical Investigation, 2015, v. 125, n. 2, p. 846, doi. 10.1172/JCI73688
By:
- Steculorum, Sophie M.;
- Collden, Gustav;
- Coupe, Berengere;
- Croizier, Sophie;
- Lockie, Sarah;
- Andrews, Zane B.;
- Jarosch, Florian;
- Klussmann, Sven;
- Bouret, Sebastien G.
Publication type:
Article
HIF2α signaling inhibits adherens junctional disruption in acute lung injury.
Published in:
Journal of Clinical Investigation, 2015, v. 125, n. 2, p. 652, doi. 10.1172/JCI77701
By:
- Haixia Gong;
- Rehman, Jalees;
- Haiyang Tang;
- Wary, Kishore;
- Mittal, Manish;
- Chatturvedi, Pallavi;
- Youyang Zhao;
- Komorova, Yulia A.;
- Vogel, Stephen M.;
- Malik, Asrar B.
Publication type:
Article
Polycystin-1 maturation requires polycystin-2 in a dose-dependent manner.
Published in:
Journal of Clinical Investigation, 2015, v. 125, n. 2, p. 607, doi. 10.1172/JCI76972
By:
- Gainullin, Vladimir G.;
- Hopp, Katharina;
- Ward, Christopher J.;
- Hommerding, Cynthia J.;
- Harris, Peter C.
Publication type:
Article
PINK1 deficiency impairs mitochondrial homeostasis and promotes lung fibrosis.
Published in:
Journal of Clinical Investigation, 2015, v. 125, n. 2, p. 521, doi. 10.1172/JCI74942
By:
- Bueno, Marta;
- Yen-Chun Lai;
- Romero, Yair;
- Brands, Judith;
- St. Croix, Claudette M.;
- Kamga, Christelle;
- Corey, Catherine;
- Herazo-Maya, Jose D.;
- Sembrat, John;
- Lee, Janet S.;
- Duncan, Steve R.;
- Rojas, Mauricio;
- Shiva, Sruti;
- Chu, Charleen T.;
- Mora, Ana L.
Publication type:
Article
Vascular adhesion protein-1 promotes liver inflammation and drives hepatic fibrosis.
Published in:
Journal of Clinical Investigation, 2015, v. 125, n. 2, p. 501, doi. 10.1172/JCI73722
By:
- Weston, Chris J.;
- Shepherd, Emma L.;
- Claridge, Lee C.;
- Rantakari, Pia;
- Curbishley, Stuart M.;
- Tomlinson, Jeremy W.;
- Hubscher, Stefan G.;
- Reynolds, Gary M.;
- Aalto, Kristiina;
- Anstee, Quentin M.;
- Jalkanen, Sirpa;
- Salmi, Marko;
- Smith, David J.;
- Day, Christopher P.;
- Adams, David H.
Publication type:
Article
Designer aminoglycosides prevent cochlear hair cell loss and hearing loss.
Published in:
Journal of Clinical Investigation, 2015, v. 125, n. 2, p. 583, doi. 10.1172/JCI77424
By:
- Huth, Markus E.;
- Kyu-Hee Han;
- Sotoudeh, Kayvon;
- Yi-Ju Hsieh;
- Effertz, Thomas;
- Vu, Andrew A.;
- Verhoeven, Sarah;
- Hsieh, Michael H.;
- Greenhouse, Robert;
- Cheng, Alan G.;
- Ricci, Anthony J.
Publication type:
Article
Retinoid X receptors orchestrate osteoclast differentiation and postnatal bone remodeling.
Published in:
Journal of Clinical Investigation, 2015, v. 125, n. 2, p. 809, doi. 10.1172/JCI77186
By:
- Menéndez-Gutiérrez, María P.;
- Rőszer, Tamás;
- Fuentes, Lucía;
- Núñez, Vanessa;
- Escolano, Amelia;
- Redondo, Juan Miguel;
- De Clerck, Nora;
- Metzger, Daniel;
- Valledor, Annabel F.;
- Ricote, Mercedes
Publication type:
Article
Annexin1 regulates DC efferocytosis and cross-presentation during Mycobacterium tuberculosis infection.
Published in:
Journal of Clinical Investigation, 2015, v. 125, n. 2, p. 752, doi. 10.1172/JCI77014
By:
- Tzelepis, Fanny;
- Verway, Mark;
- Daoud, Jamal;
- Gillard, Joshua;
- Hassani-Ardakani, Kimya;
- Dunn, Jonathan;
- Downey, Jeffrey;
- Gentile, Marilena Elena;
- Jaworska, Joanna;
- Sanchez, Anthony Michel Jean;
- Nédélec, Yohann;
- Vali, Hojatollah;
- Tabrizian, Maryam;
- Scott Kristof, Arnold;
- Luther King, Irah;
- Bruno Barreiro, Luis;
- Divangahi, Maziar
Publication type:
Article
Disrupting SUMOylation enhances transcriptional function and ameliorates polyglutamine androgen receptor--mediated disease.
Published in:
Journal of Clinical Investigation, 2015, v. 125, n. 2, p. 831, doi. 10.1172/JCI73214
By:
- Chua, Jason P.;
- Reddy, Satya L.;
- Zhigang Yu;
- Giorgetti, Elisa;
- Montie, Heather L.;
- Mukherjee, Sarmistha;
- Higgins, Jake;
- McEachin, Richard C.;
- Robins, Diane M.;
- Merry, Diane E.;
- Iñiguez-Lluhí, Jorge A.;
- Lieberman, Andrew P.
Publication type:
Article
The HMGB1/RAGE axis triggers neutrophil-mediated injury amplification following necrosis.
Published in:
Journal of Clinical Investigation, 2015, v. 125, n. 2, p. 539, doi. 10.1172/JCI76887
By:
- Huebener, Peter;
- Pradere, Jean-Philippe;
- Hernandez, Celine;
- Geum-Youn Gwak;
- Caviglia, Jorge Matias;
- Mu, Xueru;
- Loike, John D.;
- Jenkins, Rosalind E.;
- Antoine, Daniel J.;
- Schwabe, Robert F.
Publication type:
Article
MHCII-independent CD4<sup>+</sup> T cells protect injured CNS neurons via IL-4.
Published in:
Journal of Clinical Investigation, 2015, v. 125, n. 2, p. 699, doi. 10.1172/JCI76210
By:
- Walsh, James T.;
- Hendrix, Sven;
- Boato, Francesco;
- Smirnov, Igor;
- Jingjing Zheng;
- Lukens, John R.;
- Gadani, Sachin;
- Hechler, Daniel;
- Gölz, Greta;
- Rosenberger, Karen;
- Kammertöns, Thomas;
- Vogt, Johannes;
- Vogelaar, Christina;
- Siffrin, Volker;
- Radjavi, Ali;
- Fernandez-Castaneda, Anthony;
- Gaultier, Alban;
- Gold, Ralf;
- Kanneganti, Thirumala-Devi;
- Nitsch, Robert
Publication type:
Article
Evasion of inflammasome activation by microbial pathogens.
Published in:
Journal of Clinical Investigation, 2015, v. 125, n. 2, p. 469, doi. 10.1172/JCI75254
By:
- Ulland, Tyler K.;
- Ferguson, Polly J.;
- Sutterwala, Fayyaz S.
Publication type:
Article
TLR4 genotype and environmental LPS mediate RSV bronchiolitis through Th2 polarization.
Published in:
Journal of Clinical Investigation, 2015, v. 125, n. 2, p. 571, doi. 10.1172/JCI75183
By:
- Caballero, Mauricio T.;
- Serra, M. Elina;
- Acosta, Patricio L.;
- Marzec, Jacqui;
- Gibbons, Luz;
- Salim, Maximiliano;
- Rodriguez, Andrea;
- Reynaldi, Andrea;
- Garcia, Alejandro;
- Bado, Daniela;
- Buchholz, Ursula J.;
- Hijano, Diego R.;
- Coviello, Silvina;
- Newcomb, Dawn;
- Bellabarba, Miguel;
- Ferolla, Fausto M.;
- Libster, Romina;
- Berenstein, Ada;
- Siniawaski, Susana;
- Blumetti, Valeria
Publication type:
Article
The next steps in next-gen sequencing of cancer genomes.
Published in:
Journal of Clinical Investigation, 2015, v. 125, n. 2, p. 462, doi. 10.1172/JCI68339
By:
- Hayes, D. Neil;
- Kim, William Y.
Publication type:
Article
Tumor-specific cytotoxic T lymphocyte activity determines colorectal cancer patient prognosis.
Published in:
Journal of Clinical Investigation, 2015, v. 125, n. 2, p. 739, doi. 10.1172/JCI74894
By:
- Reissfelder, Christoph;
- Stamova, Slava;
- Gossmann, Christina;
- Braun, Marion;
- Bonertz, Andreas;
- Walliczek, Ute;
- Grimm, Mario;
- Rahbari, Nuh N.;
- Koch, Moritz;
- Saadati, Maral;
- Benner, Axel;
- Büchler, Markus W.;
- Jäger, Dirk;
- Halama, Niels;
- Khazaie, Khashayarsha;
- Weitz, Jürgen;
- Beckhove, Philipp
Publication type:
Article