Works matching IS 00219738 AND DT 2015 AND VI 125 AND IP 1

Results: 50

Purkinje neuron Ca2+ influx reduction rescues ataxia in SCA28 model.

Published in:

2015

By:

Maltecca, Francesca;
Baseggio, Elisa;
Consolato, Francesco;
Mazza, Davide;
Podini, Paola;
Young, Samuel M Jr;
Drago, Ilaria;
Bahr, Ben A;
Puliti, Aldamaria;
Codazzi, Franca;
Quattrini, Angelo;
Casari, Giorgio

Publication type:

journal article

Metabolic programming and PDHK1 control CD4+ T cell subsets and inflammation.

Published in:

2015

By:

Gerriets, Valerie A;
Kishton, Rigel J;
Nichols, Amanda G;
Macintyre, Andrew N;
Inoue, Makoto;
Ilkayeva, Olga;
Winter, Peter S;
Liu, Xiaojing;
Priyadharshini, Bhavana;
Slawinska, Marta E;
Haeberli, Lea;
Huck, Catherine;
Turka, Laurence A;
Wood, Kris C;
Hale, Laura P;
Smith, Paul A;
Schneider, Martin A;
MacIver, Nancie J;
Locasale, Jason W;
Newgard, Christopher B

Publication type:

journal article

Podoplanin negatively regulates CD4+ effector T cell responses.

Published in:

2015

By:

Peters, Anneli;
Burkett, Patrick R;
Sobel, Raymond A;
Buckley, Christopher D;
Watson, Steve P;
Bettelli, Estelle;
Kuchroo, Vijay K

Publication type:

journal article

Corrigendum.

Published in:: 2015
Publication type:: Correction Notice

Corrigendum.

Published in:: 2015
Publication type:: Correction Notice

Anti-thymocyte globulin/G-CSF treatment preserves β cell function in patients with established type 1 diabetes.

Published in:

2015

By:

Haller, Michael J.;
Gitelman, Stephen E.;
Gottlieb, Peter A.;
Michels, Aaron W.;
Rosenthal, Stephen M.;
Shuster, Jonathan J.;
Zou, Baiming;
Brusko, Todd M.;
Hulme, Maigan A.;
Wasserfall, Clive H.;
Mathews, Clayton E.;
Atkinson, Mark A.;
Schatz, Desmond A.

Publication type:

journal article

Naturally selected hepatitis C virus polymorphisms confer broad neutralizing antibody resistance.

Published in:

Journal of Clinical Investigation, 2015, v. 125, n. 1, p. 437, doi. 10.1172/JCI78794

By:

Bailey, Justin R.;
Wasilewski, Lisa N.;
Snider, Anna E.;
El-Diwany, Ramy;
Osburn, William O.;
Zhenyong Keck;
Foung, Steven K. H.;
Ray, Stuart C.

Publication type:

Article

TALEN-mediated targeting of HPV oncogenes ameliorates HPV-related cervical malignancy.

Published in:

Journal of Clinical Investigation, 2015, v. 125, n. 1, p. 425, doi. 10.1172/JCI78206

By:

Zheng Hu;
Wencheng Ding;
Da Zhu;
Lan Yu;
Xiaohui Jiang;
Xiaoli Wang;
Changlin Zhang;
Liming Wang;
Teng Ji;
Dan Liu;
Dan He;
Xi Xia;
Tao Zhu;
Juncheng Wei;
Peng Wu;
Changyu Wang;
Ling Xi;
Qinglei Gao;
Gang Chen;
Rong Liu

Publication type:

Article

Defective removal of ribonucleotides from DNA promotes systemic autoimmunity.

Published in:

Journal of Clinical Investigation, 2015, v. 125, n. 1, p. 413, doi. 10.1172/JCI78001

By:

Gunther, Claudia;
Kind, Barbara;
Reijns, Martin A. M.;
Berndt, Nicole;
Martinez-Bueno, Manuel;
Wolf, Christine;
Tüngler, Victoria;
Chara, Osvaldo;
Young Ae Lee;
Hübner, Norbert;
Bicknell, Louise;
Blum, Sophia;
Krug, Claudia;
Schmidt, Franziska;
Kretschmer, Stefanie;
Koss, Sarah;
Astell, Katy R.;
Ramantani, Georgia;
Bauerfeind, Anja;
Morris, David L.

Publication type:

Article

Genetically engineered SCN5A mutant pig hearts exhibit conduction defects and arrhythmias.

Published in:

Journal of Clinical Investigation, 2015, v. 125, n. 1, p. 403, doi. 10.1172/JCI76919

By:

Park, David S.;
Cerrone, Marina;
Morley, Gregory;
Vasquez, Carolina;
Fowler, Steven;
Nian Liu;
Bernstein, Scott A.;
Fang-Yu Liu;
Jie Zhang;
Rogers, Christopher S.;
Priori, Silvia G.;
Chinitz, Larry A.;
Fishman, Glenn I.

Publication type:

Article

Intestinal farnesoid X receptor signaling promotes nonalcoholic fatty liver disease.

Published in:

Journal of Clinical Investigation, 2015, v. 125, n. 1, p. 386, doi. 10.1172/JCI76738

By:

Changtao Jiang;
Cen Xie;
Fei Li;
Limin Zhang;
Nichols, Robert C.;
Krausz, Kristopher W.;
Jingwei Cai;
Yunpeng Qi;
Zhong-Ze Fang;
Shogo Takahashi;
Naoki Tanaka;
Desai, Dhimant;
Amin, Shantu C.;
Albert, Istvan;
Patterson, Andrew D.;
Gonzalez, Frank J.

Publication type:

Article

Targeting development of incretin-producing cells increases insulin secretion.

Published in:

Journal of Clinical Investigation, 2015, v. 125, n. 1, p. 379, doi. 10.1172/JCI75838

By:

Petersen, Natalia;
Reimann, Frank;
van Es, Johan H.;
van den Berg, Bernard M.;
Kroone, Chantal;
Pais, Ramona;
Jansen, Erik;
Clevers, Hans;
Gribble, Fiona M.;
de Koning, Eelco J. P.

Publication type:

Article

CXCR3 promotes plaque formation and behavioral deficits in an Alzheimer's disease model.

Published in:

Journal of Clinical Investigation, 2015, v. 125, n. 1, p. 365, doi. 10.1172/JCI66771

By:

Krauthausen, Marius;
Kummer, Markus P.;
Zimmermann, Julian;
Reyes-Irisarri, Elisabet;
Terwel, Dick;
Bulic, Bruno;
Heneka, Michael T.;
Müller, Marcus

Publication type:

Article

Prostaglandin signaling suppresses beneficial microglial function in Alzheimer's disease models.

Published in:

Journal of Clinical Investigation, 2015, v. 125, n. 1, p. 350, doi. 10.1172/JCI77487

By:

Johansson, Jenny U.;
Woodling, Nathaniel S.;
Qian Wang;
Panchal, Maharshi;
Xibin Liang;
Trueba-Saiz, Angel;
Brown, Holden D.;
Mhatre, Siddhita D.;
Loui, Taylor;
Andreasson, Katrin I.

Publication type:

Article

Glucokinase activity in the arcuate nucleus regulates glucose intake.

Published in:

Journal of Clinical Investigation, 2015, v. 125, n. 1, p. 337, doi. 10.1172/JCI77172

By:

Hussain, Syed;
Richardson, Errol;
Yue Ma;
Holton, Christopher;
De Backer, Ivan;
Buckley, Niki;
Dhillo, Waljit;
Bewick, Gavin;
Shuai Zhang;
Carling, David;
Bloom, Steve;
Gardiner, James

Publication type:

Article

Smooth-muscle BMAL1 participates in blood pressure circadian rhythm regulation.

Published in:

Journal of Clinical Investigation, 2015, v. 125, n. 1, p. 324, doi. 10.1172/JCI76881

By:

Zhongwen Xie;
Wen Su;
Shu Liu;
Guogang Zhao;
Esser, Karyn;
Schroder, Elizabeth A.;
Lefta, Mellani;
Stauss, Harald M.;
Zhenheng Guo;
Ming Cui Gong

Publication type:

Article

Sumoylated HSP90 is a dominantly inherited plasma cell dyscrasias risk factor.

Published in:

Journal of Clinical Investigation, 2015, v. 125, n. 1, p. 316, doi. 10.1172/JCI76802

By:

Preuss, Klaus-Dieter;
Pfreundschuh, Michael;
Fadle, Natalie;
Regitz, Evi;
Kubuschok, Boris

Publication type:

Article

LMP1-deficient Epstein-Barr virus mutant requires T cells for lymphomagenesis.

Published in:

Journal of Clinical Investigation, 2015, v. 125, n. 1, p. 304, doi. 10.1172/JCI76357

By:

Shi-Dong Ma;
Xuequn Xu;
Plowshay, Julie;
Ranheim, Erik A.;
Burlingham, William J.;
Jensen, Jeffrey L.;
Asimakopoulos, Fotis;
Weihua Tang;
Gulley, Margaret L.;
Cesarman, Ethel;
Cumperz, Jenny E.;
Kenney, Shannon C.

Publication type:

Article

Follicular helper T cell signature in type 1 diabetes.

Published in:

2015

By:

Kenefeck, Rupert;
Chun Jing Wang;
Kapadi, Tauseef;
Wardzinski, Lukasz;
Attridge, Kesley;
Clough, Louise E.;
Heuts, Frank;
Kogimtzis, Alexandras;
Patel, Sapna;
Rosenthal, Miranda;
Masahiro Ono;
Sansom, David M.;
Narendran, Parth;
Walker, Lucy S. K.;
Wang, Chun Jing;
Kogimtzis, Alexandros;
Ono, Masahiro

Publication type:

journal article

Cell-surface MHC density profiling reveals instability of autoimmunity-associated HLA.

Published in:

Journal of Clinical Investigation, 2015, v. 125, n. 1, p. 275, doi. 10.1172/JCI74961

By:

Hiroko Miyadera;
Jun Ohashi;
Lernmark, Åke;
Toshio Kitamura;
Katsushi Tokunaga

Publication type:

Article

Purkinje neuron Ca2+ influx reduction rescues ataxia in SCA28 model.

Published in:

Journal of Clinical Investigation, 2015, v. 125, n. 1, p. 263, doi. 10.1172/JCI74770

By:

Maltecca, Franceca;
Baseggio, Elisa;
Consolato, Francesco;
Mazza, Davide;
Podini, Paola;
Young Jr., Samuel M.;
Drago, Ilaria;
Bahr, Ben A.;
Puliti, Aldamaria;
Codazzi, Franca;
Quattrini, Angelo;
Casari, Giorgio

Publication type:

Article

Exome sequencing reveals MCM8 mutation underlies ovarian failure and chromosomal instability.

Published in:

Journal of Clinical Investigation, 2015, v. 125, n. 1, p. 258, doi. 10.1172/jci78473

By:

AlAsiri, Saleh;
Basit, Sulman;
Wood-Trageser, Michelle A.;
Yatsenko, Svetlana A.;
Jeffries, Elizabeth P.;
Surti, Urvashi;
Ketterer, Deborah M.;
Afzal, Sibtain;
Ramzan, Khushnooda;
Haque, Muhammad Faiyaz-UI;
Huaiyang Jiang;
Trakselis, Michael A.;
Rajkovic, Aleksandar

Publication type:

Article

Clinical trial demonstrates exercise following bariatric surgery improves insulin sensitivity.

Published in:

2015

By:

Coen, Paul M.;
Tanner, Charles J.;
Helbling, Nicole L.;
Dubis, Gabriel S.;
Hames, Kazanna C.;
Hui Xie;
Eid, George M.;
Stefanovic-Racic, Maja;
Toledo, Frederico G. S.;
Jakicic, John M.;
Houmard, Joseph A.;
Coodpaster, Bret H.;
Xie, Hui;
Goodpaster, Bret H

Publication type:

journal article

Long-term potentiation decay and memory loss are mediated by AMPAR endocytosis.

Published in:

Journal of Clinical Investigation, 2015, v. 125, n. 1, p. 234, doi. 10.1172/JCI77888

By:

Zhifang Dong;
Huili Han;
Hongjie Li;
Yanrui Bai;
Wei Wang;
Man Tu;
Yan Peng;
Limin Zhou;
Wenting He;
Xiaobin Wu;
Tao Tan;
Mingjing Liu;
Xiaoyan Wu;
Weihui Zhou;
Wuyang Jin;
Shu Zhang;
Sacktor, Todd Charlton;
Tingyu Li;
Weihong Song;
Yu Tian Wang

Publication type:

Article

Rare codons capacitate Kras-driven de novo tumorigenesis.

Published in:

Journal of Clinical Investigation, 2015, v. 125, n. 1, p. 222, doi. 10.1172/JCI77627

By:

Pershing, Nicole L. K.;
Lampson, Benjamin L.;
Belsky, Jason A.;
Kaltenbrun, Erin;
MacAlpine, David M.;
Counter, Christopher M.

Publication type:

Article

Intronic locus determines SHROOM3 expression and potentiates renal allograft fibrosis.

Published in:

2015

By:

Menon, Madhav C.;
Chuang, Peter Y.;
Zhengzhe Li;
Chengguo Wei;
Weijia Zhang;
Yi Luan;
Zhengzi Yi;
Huabao Xiong;
Woytovich, Christopher;
Greene, Ilana;
Overbey, Jessica;
Rosales, Ivy;
Bagiella, Emilia;
Rong Chen;
Meng Ma;
Li Li;
Wei Ding;
Djamali, Arjang;
Saminego, Millagros;
O'Connell, Philip J.

Publication type:

journal article

Metabolic programming and PDHK1 control CD4+ T cell subsets and inflammation.

Published in:

Journal of Clinical Investigation, 2015, v. 125, n. 1, p. 194, doi. 10.1172/JCI76012

By:

Cerriets, Valerie A.;
Kishton, Rigel J.;
Nichols, Amanda C.;
Macintyre, Andrew N.;
Makoto Inoue;
Ilkayeva, Olga;
Winter, Peter S.;
Xiaojing Liu;
Priyadharshini, Bhavana;
Slawinska, Marta E.;
Haeberli, Lea;
Huck, Catherine;
Turka, Laurence A.;
Wood, Kris C.;
Hale, Laura P.;
Smith, Paul A.;
Schneider, Martin A.;
Maclver, Nancie J.;
Locasale, Jason W.;
Newgard, Christopher B.

Publication type:

Article

Hepatic TRAP80 selectively regulates lipogenic activity of liver X receptor.

Published in:

Journal of Clinical Investigation, 2015, v. 125, n. 1, p. 183, doi. 10.1172/JCI73615

By:

Ceun Hyang Kim;
Gyun-Sik Oh;
Jin Yoon;
Gang Gu Lee;
Ki-Up Lee;
Seung-Whan Kim

Publication type:

Article

Protein tyrosine phosphatase-σ regulates hematopoietic stem cell-repopulating capacity.

Published in:

Journal of Clinical Investigation, 2015, v. 125, n. 1, p. 177, doi. 10.1172/JCI77866

By:

Quarmyne, Mamie;
Doan, Phuong L.;
Himburg, Heather A.;
Xiao Yan;
Mai Nakamura;
Liman Zhao;
Chao, Nelson J.;
Chute, John P.

Publication type:

Article

Human pDCs preferentially sense enveloped hepatitis A virions.

Published in:

Journal of Clinical Investigation, 2015, v. 125, n. 1, p. 169, doi. 10.1172/JCI77527

By:

Zongdi Feng;
You Li;
McKnight, Kevin L.;
Hensley, Lucinda;
Lanford, Robert E.;
Walker, Christopher M.;
Lemon, Stanley M.

Publication type:

Article

Survivin-specific T cell receptor targets tumor but not T cells.

Published in:

Journal of Clinical Investigation, 2015, v. 125, n. 1, p. 157, doi. 10.1172/JCI75876

By:

Arber, Caroline;
Xiang Feng;
Abhyankar, Harshal;
Romero, Errika;
Meng-Fen Wu;
Heslop, Helen E.;
Barth, Patrick;
Dotti, Cianpietro;
Savoldo, Barbara

Publication type:

Article

Anti-microRNA-21 oligonucleotides prevent Alport nephropathy progression by stimulating metabolic pathways.

Published in:

Journal of Clinical Investigation, 2015, v. 125, n. 1, p. 141, doi. 10.1172/JCI75852

By:

Gomez, Ivan C.;
MacKenna, Deidre A.;
Johnson, Bryce G.;
Kaimal, Vivek;
Roach, Allie M.;
Shuyu Ren;
Naoki Nakagawa;
Cuiyan Xin;
Newitt, Rick;
Pandya, Shweta;
Tai-He Xia;
Xueqing Liu;
Borza, Dorin-Bogdan;
Grafals, Monica;
Shankland, Stuart J.;
Himmelfarb, Jonathan;
Portilla, Didier;
Shiguang Liu;
Chau, B. Nelson;
Duffield, Jeremy S.

Publication type:

Article

Podoplanin negatively regulates CD4+ effector T cell responses.

Published in:

Journal of Clinical Investigation, 2015, v. 125, n. 1, p. 129, doi. 10.1172/JCI74685

By:

Peters, Anneli;
Burkett, Patrick R.;
Sobel, Raymond A.;
Buckley, Christopher D.;
Watson, Steve P.;
Bettelli, Estelle;
Kuchroo, Vijay K.

Publication type:

Article

mTORC2 regulates renal tubule sodium uptake by promoting ENaC activity.

Published in:

Journal of Clinical Investigation, 2015, v. 125, n. 1, p. 117, doi. 10.1172/JCI73935

By:

Gleason, Catherine E.;
Frindt, Gustavo;
Chih-jen Cheng;
Ng, Michael;
Kidwai, Atif;
Rashmi, Priyanka;
Lang, Florian;
Baum, Michel;
Palmer, Lawrence G.;
Pearce, David

Publication type:

Article

Viral-mediated RdCVF and RdCVFL expression protects cone and rod photoreceptors in retinal degeneration.

Published in:

Journal of Clinical Investigation, 2015, v. 125, n. 1, p. 105, doi. 10.1172/JCI65654

By:

Byrne, Leah C.;
Dalkara, Deniz;
Luna, Gabriel;
Fisher, Steven K.;
Clérin, Emmanuelle;
Sahel, Jose-Alain;
Léveillard, Thierry;
Flannery, John G.

Publication type:

Article

AGS, SLE, and RNASEH2 mutations: translating insights into therapeutic advances.

Published in:

Journal of Clinical Investigation, 2015, v. 125, n. 1, p. 102, doi. 10.1172/jci78533

By:

Pendergraft III, William F.;
Means, Terry K.

Publication type:

Article

Bringing home the bacon? The next step in cardiac sodium channelopathies.

Published in:

Journal of Clinical Investigation, 2015, v. 125, n. 1, p. 99, doi. 10.1172/JCI80014

By:

Wilde, Arthur A. M.;
Postema, Pieter C.

Publication type:

Article

The genetics of hepatitis C virus underlie its ability to escape humoral immunity.

Published in:

Journal of Clinical Investigation, 2015, v. 125, n. 1, p. 97, doi. 10.1172/JCI79424

By:

Kolls, Jay K.;
Szabo, Gyongyi

Publication type:

Article

Immune therapy for treating type 1 diabetes: challenging existing paradigms.

Published in:

2015

By:

Skyler, Jay S.

Publication type:

journal article

Essential role for autophagy in life span extension.

Published in:

Journal of Clinical Investigation, 2015, v. 125, n. 1, p. 85, doi. 10.1172/JCI73946

By:

Madeo, Frank;
Zimmermann, Andreas;
Maiuri, Maria Chiara;
Kroemer, Guido

Publication type:

Article

Immunologic manifestations of autophagy.

Published in:

2015

By:

Deretic, Vojo;
Kimura, Tomonori;
Timmins, Graham;
Moseley, Pope;
Chauhan, Santosh;
Mandell, Michael

Publication type:

journal article

Autophagy and neurodegeneration.

Published in:

Journal of Clinical Investigation, 2015, v. 125, n. 1, p. 65, doi. 10.1172/JCI73944

By:

Frake, Rebecca A.;
Ricketts, Thomas;
Menzies, Fiona M.;
Rubinsztein, David C.

Publication type:

Article

Autophagy in cardiovascular biology.

Published in:

2015

By:

Lavandero, Sergio;
Chiong, Mario;
Rothermel, Beverly A.;
Hill, Joseph A.

Publication type:

journal article

Pharmacologic agents targeting autophagy.

Published in:

Journal of Clinical Investigation, 2015, v. 125, n. 1, p. 5, doi. 10.1172/JCI73937

By:

Vakifahmetoglu-Norberg, Helin;
Hong-guang Xia;
Junying Yuan

Publication type:

Article

The role for autophagy in cancer.

Published in:

Journal of Clinical Investigation, 2015, v. 125, n. 1, p. 42, doi. 10.1172/JCI73941

By:

White, Eileen

Publication type:

Article

The functional and pathologic relevance of autophagy proteases.

Published in:

Journal of Clinical Investigation, 2015, v. 125, n. 1, p. 33, doi. 10.1172/JCI73940

By:

Fernández, Álvaro F.;
López-Otín, Carlos

Publication type:

Article

mTOR: a pharmacologic target for autophagy regulation.

Published in:

2015

By:

Young Chul Kim;
Kun-Liang Guan;
Kim, Young Chul;
Guan, Kun-Liang

Publication type:

journal article

Development of autophagy inducers in clinical medicine.

Published in:

Journal of Clinical Investigation, 2015, v. 125, n. 1, p. 14, doi. 10.1172/JCI73938

By:

Levine, Beth;
Packer, Milton;
Codogno, Patrice

Publication type:

Article

Autophagy in cellular metabolism and cancer.

Published in:

Journal of Clinical Investigation, 2015, v. 125, n. 1, p. 47, doi. 10.1172/JCI73942

By:

Xuejun Jiang;
Overholtzer, Michael;
Thompson, Craig B.

Publication type:

Article

Autophagy: a druggable process that is deregulated in aging and human disease.

Published in:

Journal of Clinical Investigation, 2015, v. 125, n. 1, p. 1, doi. 10.1172/JCI78652

By:

Kroemer, Guido

Publication type:

Article