Works matching IS 00219738 AND DT 2014 AND VI 124 AND IP 9

Results: 53

Play down protein to play up metabolism?

Published in:

2014

By:

Müller, Timo D;
Tschöp, Matthias H

Publication type:

journal article

Corrigendum.

Published in:: 2014
Publication type:: Correction Notice

Inflammatory lymphangiogenesis in postpartum breast tissue remodeling.

Published in:

2014

By:

Swartz, Melody A

Publication type:

journal article

IL-1β inhibition in autoimmune inner ear disease: can you hear me now?

Published in:

2014

By:

Rauch, Steven D

Publication type:

journal article

Conversations with Lasker giants.

Published in:

Journal of Clinical Investigation, 2014, v. 124, n. 9, p. 3679, doi. 10.1172/JCI78053

By:

Neill, Ushma S.

Publication type:

Article

CXCR3⁺CCR5⁺ T cells and autoimmune diseases: guilty as charged?

Published in:

2014

By:

Mackay, Charles R

Publication type:

journal article

The imperative to invest in science has never been greater.

Published in:

Journal of Clinical Investigation, 2014, v. 124, n. 9, p. 3680, doi. 10.1172/JCI77894

By:

Coughlin, Shaun;
Diamond, Betty;
Erzurum, Serpil;
Fried, Linda P.;
Jameson, Larry;
Kaushansk, Kenneth;
Klotman, Mary E.;
Lemon, Stanley;
Mitchell, Beverly;
Rothman, Paul;
Sawyers, Charles;
Seidman, Christine;
Somlo, Stefan

Publication type:

Article

CXCR3+CCR5+ T cells and autoimmune diseases: guilty as charged?

Published in:

Journal of Clinical Investigation, 2014, v. 124, n. 9, p. 3682, doi. 10.1172/JCI77837

By:

Mackay, Charles R.

Publication type:

Article

Inflammatory lymphangiogenesis in postpartum breast tissue remodeling.

Published in:

Journal of Clinical Investigation, 2014, v. 124, n. 9, p. 3704, doi. 10.1172/JCI77765

By:

Swartz, Melody A.

Publication type:

Article

VEGF-C-dependent stimulation of lymphatic function ameliorates experimental inflammatory bowel disease.

Published in:

2014

By:

D'Alessio, Silvia;
Correale, Carmen;
Tacconi, Carlotta;
Gandelli, Alessandro;
Pietrogrande, Giovanni;
Vetrano, Stefania;
Genua, Marco;
Arena, Vincenzo;
Spinelli, Antonino;
Peyrin-Biroulet, Laurent;
Fiocchi, Claudio;
Danese, Silvio

Publication type:

journal article

Shifting FcγRIIA-ITAM from activation to inhibitory configuration ameliorates arthritis.

Published in:

2014

By:

Ben Mkaddem, Sanae;
Hayem, Gilles;
Jönsson, Friederike;
Rossato, Elisabetta;
Boedec, Erwan;
Boussetta, Tarek;
El Benna, Jamel;
Launay, Pierre;
Goujon, Jean-Michel;
Benhamou, Marc;
Bruhns, Pierre;
Monteiro, Renato C

Publication type:

journal article

Cannabidiol exerts sebostatic and antiinflammatory effects on human sebocytes.

Published in:

2014

By:

Oláh, Attila;
Tóth, Balázs I;
Borbíró, István;
Sugawara, Koji;
Szöllõsi, Attila G;
Czifra, Gabriella;
Pál, Balázs;
Ambrus, Lídia;
Kloepper, Jennifer;
Camera, Emanuela;
Ludovici, Matteo;
Picardo, Mauro;
Voets, Thomas;
Zouboulis, Christos C;
Paus, Ralf;
Bíró, Tamás

Publication type:

journal article

p38 signaling inhibits mTORC1-independent autophagy in senescent human CD8⁺ T cells.

Published in:

2014

By:

Henson, Sian M;
Lanna, Alessio;
Riddell, Natalie E;
Franzese, Ornella;
Macaulay, Richard;
Griffiths, Stephen J;
Puleston, Daniel J;
Watson, Alexander Scarth;
Simon, Anna Katharina;
Tooze, Sharon A;
Akbar, Arne N

Publication type:

journal article

Targeted p16(Ink4a) epimutation causes tumorigenesis and reduces survival in mice.

Published in:

2014

By:

Yu, Da-Hai;
Waterland, Robert A;
Zhang, Pumin;
Schady, Deborah;
Chen, Miao-Hsueh;
Guan, Yongtao;
Gadkari, Manasi;
Shen, Lanlan

Publication type:

journal article

"RAS"ling β cells to proliferate for diabetes: why do we need MEN?

Published in:

Journal of Clinical Investigation, 2014, v. 124, n. 9, p. 3698, doi. 10.1172/JCI77764

By:

García-Ocaña, Adolfo;
Stewart, Andrew F.

Publication type:

Article

Healing the injured vessel wall using microRNA-facilitated gene delivery.

Published in:

Journal of Clinical Investigation, 2014, v. 124, n. 9, p. 3694, doi. 10.1172/JCI77509

By:

Feinberg, Mark W.

Publication type:

Article

Play down protein to play up metabolism?

Published in:

Journal of Clinical Investigation, 2014, v. 124, n. 9, p. 3691, doi. 10.1172/JCI77508

By:

Müller, Timo D.;
Tschöp, Matthias H.

Publication type:

Article

Too much of a good thing: immunodeficiency due to hyperactive PI3K signaling.

Published in:

Journal of Clinical Investigation, 2014, v. 124, n. 9, p. 3688, doi. 10.1172/JCI77198

By:

Walsh, Craig M.;
Fruman, David A.

Publication type:

Article

Schlemm's canal: more than meets the eye, lymphatics in disguise.

Published in:

2014

By:

Karpinich, Natalie O.;
Caron, Kathleen M.

Publication type:

journal article

IL-1β inhibition in autoimmune inner ear disease: can you hear me now?

Published in:

2014

By:

Rauch, Steven D.

Publication type:

Case Study

Gene therapy enhances chemotherapy tolerance and efficacy in glioblastoma patients.

Published in:

2014

By:

Adair, Jennifer E.;
Johnston, Sandra K.;
Mrugala, Maciej M.;
Beard, Brian C.;
Guyman, Laura A.;
Baldock, Anne L.;
Bridge, Carly A.;
Hawkins-Daarud, Andrea;
Gori, Jennifer L.;
Born, Donald E.;
Gonzalez-Cuyar, Luis F.;
Silbergeld, Daniel L.;
Rockne, Russell C.;
Storer, Barry E.;
Rockhill, Jason K.;
Swanson, Kristin R.;
Kiem, Hans-Peter

Publication type:

journal article

Targeted p16Ink4a epimutation causes tumorigenesis and reduces survival in mice.

Published in:

Journal of Clinical Investigation, 2014, v. 124, n. 9, p. 3708, doi. 10.1172/JCI76507

By:

Da-Hai Yu;
Waterland, Robert A.;
Pumin Zhang;
Schady, Deborah;
Miao-Hsueh Chen;
Yongtao Guan;
Gadkari, Manasi;
Lanlan Shen

Publication type:

Article

Early efficacy trial of anakinra in corticosteroid-resistant autoimmune inner ear disease.

Published in:

Journal of Clinical Investigation, 2014, v. 124, n. 9, p. 4115, doi. 10.1172/JCI76503

By:

Vambutas, Andrea;
Lesser, Martin;
Mullooly, Virginia;
Pathak, Shresh;
Zahtz, Gerald;
Rosen, Lisa;
Goldofsky, Elliot

Publication type:

Article

Canonical WNT signaling components in vascular development and barrier formation.

Published in:

Journal of Clinical Investigation, 2014, v. 124, n. 9, p. 3825, doi. 10.1172/JCI76431

By:

Yulian Zhou;
Yanshu Wang;
Tischfield, Max;
Williams, John;
Smallwood, Philip M.;
Rattner, Amir;
Makoto M. Taketo;
Nathans, Jeremy

Publication type:

Article

Proteasome function is required for platelet production.

Published in:

Journal of Clinical Investigation, 2014, v. 124, n. 9, p. 3757, doi. 10.1172/JCI75247

By:

Shi, Dallas S.;
Smith, Matthew C. P.;
Campbell, Robert A.;
Zimmerman, Patrick W.;
Franks, Zechariah B.;
Kraemer, Bjorn F.;
Machlus, Kellie R.;
Jing Ling;
Kamba, Patrick;
Schwertz, Hansjörg;
Rowley, Jesse W.;
Miles, Rodney R.;
Zhi-Jian Liu;
Sola-Visner, Martha;
Italiano Jr., Joseph E.;
Christensen, Hilary;
Kahr, Walter H. A.;
Li, Dean Y.;
Weyrich, Andrew S.

Publication type:

Article

Splice-correcting oligonucleotides restore BTK function in X-linked agammaglobulinemia model.

Published in:

Journal of Clinical Investigation, 2014, v. 124, n. 9, p. 4067, doi. 10.1172/JCI76175

By:

Bestas, Burcu;
Moreno, Pedro M. D.;
Blomberg, K. Emelie M.;
Mohammad, Dara K.;
Saleh, Amer F.;
Sutlu, Tolga;
Nordin, Joel Z.;
Guterstam, Peter;
Gustafsson, Manuela O.;
Kharazi, Shabnam;
Piatosa, Barbara;
Roberts, Thomas C.;
Behlke, Mark A.;
Wood, Matthew J. A.;
Gait, Michael J.;
Lundin, Karin E.;
Andaloussi, Samir El;
Månsson, Robert;
Berglöf, Anna;
Wengel, Jesper

Publication type:

Article

A selective microRNA-based strategy inhibits restenosis while preserving endothelial function.

Published in:

Journal of Clinical Investigation, 2014, v. 124, n. 9, p. 4102, doi. 10.1172/JCI76069

By:

Santulli, Gaetano;
Wronska, Anetta;
Uryu, Kunihiro;
Diacovo, Thomas G.;
Gao, Melanie;
Marx, Steven O.;
Kitajewski, Jan;
Chilton, Jamie M.;
Akat, Kemal Marc;
Tuschl, Thomas;
Marks, Andrew R.;
Totary-Jain, Hana

Publication type:

Article

PAX7 expression defines germline stem cells in the adult testis.

Published in:

Journal of Clinical Investigation, 2014, v. 124, n. 9, p. 3929, doi. 10.1172/JCI75943

By:

Aloisio, Gina M.;
Yuji Nakada;
Saatcioglu, Hatice D.;
Peña, Christopher G.;
Baker, Michael D.;
Tarnawa, Edward D.;
Mukherjee, Jishnu;
Manjunath, Hema;
Bugde, Abhijit;
Sengupta, Anita L.;
Amatruda, James F.;
Cuevas, Ileana;
Hamra, F. Kent;
Castrillon, Diego H.

Publication type:

Article

A human immunodeficiency caused by mutations in the PIK3R1 gene.

Published in:

Journal of Clinical Investigation, 2014, v. 124, n. 9, p. 3923, doi. 10.1172/JCI75746

By:

Deau, Marie-Céline;
Heurtier, Lucie;
Frange, Pierre;
Suarez, Felipe;
Bole-Feysot, Christine;
Nitschke, Patrick;
Cavazzana, Marina;
Picard, Capucine;
Durandy, Anne;
Fischer, Alain;
Kracker, Sven

Publication type:

Article

PPARγ ablation sensitizes proopiomelanocortin neurons to leptin during high-fat feeding.

Published in:

Journal of Clinical Investigation, 2014, v. 124, n. 9, p. 4017, doi. 10.1172/JCI76220

By:

Lihong Long;
Chitoku Toda;
Jing Kwon Jeong;
Horvath, Tamas L.;
Diano, Sabrina

Publication type:

Article

FCCR2C polymorphisms associate with HIV-1 vaccine protection in RV144 trial.

Published in:

Journal of Clinical Investigation, 2014, v. 124, n. 9, p. 3879, doi. 10.1172/JCI75539

By:

Shuying S. Li;
Gilbert, Peter B.;
Tomaras, Georgia D.;
Kijak, Gustavo;
Ferrari, Guido;
Thomas, Rasmi;
Chul-Woo Pyo;
Zolla-Pazner, Susan;
Montefiori, David;
Hua-Xin Liao;
Nabel, Gary;
Pinter, Abraham;
Evans, David T.;
Gottardo, Raphael;
Dai, James Y.;
Janes, Holly;
Morris, Daryl;
Youyi Fong;
Edlefsen, Paul T.;
Fusheng Li

Publication type:

Article

The Schlemm's canal is a VEGF-C/VEGFR-3-responsive lymphatic-like vessel.

Published in:

Journal of Clinical Investigation, 2014, v. 124, n. 9, p. 3975, doi. 10.1172/JCI75395

By:

Aspelund, Aleksanteri;
Tammela, Tuomas;
Antila, Salli;
Nurmi, Harri;
Leppänen, Veli-Matti;
Zarkada, Georgia;
Stanczuk, Lukas;
Francois, Mathias;
Mäkinen, Taija;
Saharinen, Pipsa;
Immonen, Ilkka;
Alitalo, Kari

Publication type:

Article

Lymphatic regulator PROX1 determines Schlemm's canal integrity and identity.

Published in:

Journal of Clinical Investigation, 2014, v. 124, n. 9, p. 3960, doi. 10.1172/JCI75392

By:

Dae-Young Park;
Junyeop Lee;
Intae Park;
Dongwon Choi;
Sunju Lee;
Sukhyun Song;
Yoonha Hwang;
Ki Yong Hong;
Yoshikazu Nakaoka;
Taija Makinen;
Pilhan Kim;
Kari Alitalo;
Young-Kwon Hong;
Gou Young Koh

Publication type:

Article

Cyclooxygenase-2-dependent lymphangiogenesis promotes nodal metastasis of postpartum breast cancer.

Published in:

2014

By:

Lyons, Traci R.;
Borges, Virginia F.;
Betts, Courtney B.;
Qiuchen Guo;
Kapoor, Puja;
Martinson, Holly A.;
Jindal, Sonali;
Schedin, Pepper;
Guo, Qiuchen

Publication type:

journal article

Development and translational imaging of a TP53 porcine tumorigenesis model.

Published in:

Journal of Clinical Investigation, 2014, v. 124, n. 9, p. 4052, doi. 10.1172/JCI75447

By:

Sieren, Jessica C.;
Meyerholz, David K.;
Xiao-Jun Wang;
Davis, Bryan T.;
Newell Jr., John D.;
Hammond, Emily;
Rohret, Judy A.;
Rohret, Frank A.;
Struzynski, Jason T.;
Goeken, J. Adam;
Naumann, Paul W.;
Leidinger, Mariah R.;
Taghiyev, Agshin;
Van Rheeden, Richard;
Hagen, Jussara;
Darbro, Benjamin W.;
Quelle, Dawn E.;
Rogers, Christopher S.

Publication type:

Article

p38 signaling inhibits mTORC1-independent autophagy in senescent human CD8+ T cells.

Published in:

Journal of Clinical Investigation, 2014, v. 124, n. 9, p. 4004, doi. 10.1172/JCI75051

By:

Henson, Sian M.;
Lanna, Alessio;
Riddell, Natalie E.;
Franzese, Ornella;
Macaulay, Richard;
Griffiths, Stephen J.;
Puleston, Daniel J.;
Scarth Watson, Alexander;
Simon, Anna Katharina;
Tooze, Sharon A.;
Akbar, Arne N.

Publication type:

Article

Shifting FcγRIIA-ITAM from activation to inhibitory configuration ameliorates arthritis.

Published in:

Journal of Clinical Investigation, 2014, v. 124, n. 9, p. 3945, doi. 10.1172/JCI74572

By:

Mkaddem, Sanae Ben;
Hayem, Gilles;
Jönsson, Friederike;
Rossato, Elisabetta;
Boedec, Erwan;
Boussetta, Tarek;
El Benna, Jamel;
Launay, Pierre;
Goujon, Jean-Michel;
Benhamou, Marc;
Bruhns, Pierre;
Monteiro, Renato C.

Publication type:

Article

Endothelial C-type natriuretic peptide maintains vascular homeostasis.

Published in:

Journal of Clinical Investigation, 2014, v. 124, n. 9, p. 4039, doi. 10.1172/JCI74281

By:

Moyes, Amie J.;
Khambata, Rayomand S.;
Villar, Inmaculada;
Bubb, Kristen J.;
Baliga, Reshma S.;
Lumsden, Natalie G.;
Fang Xiao;
Gane, Paul J.;
Rebstock, Anne-Sophie;
Worthington, Roberta J.;
Simone, Michela I.;
Mota, Filipa;
Rivilla, Fernando;
Vallejo, Susana;
Peiró, Concepción;
Ferrer, Carlos F. Sánchez;
Djordjevic, Snezana;
Caulfield, Mark J.;
MacAllister, Raymond J.;
Selwood, David L.

Publication type:

Article

Periderm prevents pathological epithelial adhesions during embryogenesis.

Published in:

Journal of Clinical Investigation, 2014, v. 124, n. 9, p. 3891, doi. 10.1172/JCI71946

By:

Richardson, Rebecca J.;
Hammond, Nigel L.;
Coulombe, Pierre A.;
Saloranta, Carola;
Nousiainen, Heidi O.;
Salonen, Riitta;
Berry, Andrew;
Hanley, Neil;
Headon, Denis;
Karikoski, Riitta;
Dixon, Michael J.

Publication type:

Article

Mitophagy-dependent necroptosis contributes to the pathogenesis of COPD.

Published in:

Journal of Clinical Investigation, 2014, v. 124, n. 9, p. 3987, doi. 10.1172/JCI74985

By:

Kenji Mizumura;
Cloonan, Suzanne M.;
Kiichi Nakahira;
Bhashyam, Abhiram R.;
Cervo, Morgan;
Tohru Kitada;
Glass, Kimberly;
Owen, Caroline A.;
Mahmood, Ashfaq;
Washko, George R.;
Shu Hashimoto;
Ryter, Stefan W.;
Choi, Augustine M. K.

Publication type:

Article

FGF21 is an endocrine signal of protein restriction.

Published in:

2014

By:

Laeger, Thomas;
Henagan, Tara M.;
Albarado, Diana C.;
Redman, Leanne M.;
Bray, George A.;
Noland, Robert C.;
Münzberg, Heike;
Hutson, Susan M.;
Gettys, Thomas W.;
Schwartz, Michael W.;
Morrison, Christopher D.

Publication type:

journal article

Hypomorphism in human NSMCE2 linked to primordial dwarfism and insulin resistance.

Published in:

Journal of Clinical Investigation, 2014, v. 124, n. 9, p. 4028, doi. 10.1172/JCI73264

By:

Payne, Felicity;
Colnaghi, Rita;
Rocha, Nuno;
Seth, Asha;
Harris, Julie;
Carpenter, Gillian;
Bottomley, William E.;
Wheeler, Eleanor;
Wong, Stephen;
Saudek, Vladimir;
Savage, David;
O'Rahilly, Stephen;
Carel, Jean-Claude;
Barroso, Inês;
O'Driscoll, Mark;
Semple, Robert

Publication type:

Article

DEAD-box helicase DP103 defines metastatic potential of human breast cancers.

Published in:

Journal of Clinical Investigation, 2014, v. 124, n. 9, p. 3807, doi. 10.1172/JCI73451

By:

Eun Myoung Shin;
Hui Sin Hay;
Moon Hee Lee;
Jen Nee Goh;
Tuan Zea Tan;
Yin Ping Sen;
See Wee Lim;
Yousef, Einas M.;
Hooi Tin Ong;
Aye Aye Thike;
Xiangjun Kong;
Zhengsheng Wu;
Mendoz, Earnest;
Wei Sun;
Salto-Tellez, Manuel;
Chwee Teck Lim;
Lobie, Peter E.;
Yoon Pin Lim;
Yap, Celestial T.;
Qi Zeng

Publication type:

Article

EGFR phosphorylation of DCBLD2 recruits TRAF6 and stimulates AKT-promoted tumorigenesis.

Published in:

Journal of Clinical Investigation, 2014, v. 124, n. 9, p. 3741, doi. 10.1172/JCI73093

By:

Haizhong Feng;
Lopez, Giselle Y.;
Chung Kwon Kim;
Alvarez, Angel;
Duncan, Christopher G.;
Ryo Nishikawa;
Motoo Nagane;
An-Jey A. Su;
Auron, Philip E.;
Hedberg, Matthew L.;
Lin Wang;
Raizer, Jeffery J.;
Kessler, John A.;
Parsa, Andrew T.;
Wei-Qiang Gao;
Sung-Hak Kim;
Mutsuko Minata;
Ichiro Nakano;
Grandis, Jennifer R.;
McLendon, Roger E.

Publication type:

Article

Ion channel TRPV1-dependent activation of PTP1B suppresses EGFR-associated intestinal tumorigenesis.

Published in:

Journal of Clinical Investigation, 2014, v. 124, n. 9, p. 3793, doi. 10.1172/JCI72340

By:

de Jong, Petrus R.;
Naoki Takahashi;
Harris, Alexandra R.;
Jihyung Lee;
Bertin, Samuel;
Jeffries, James;
Jung, Michael;
Jen Duong;
Triano, Amy I.;
Jongdae Lee;
Yaron Niv;
Herdman, David S.;
Koji Taniguchi;
Chang-Whan Kim;
Hui Dong;
Lars Eckmann;
Stanford, Stephanie M.;
Nunzio Bottini;
Corr, Maripat;
Raz, Eyal

Publication type:

Article

IL-10-producing NKT10 cells are a distinct regulatory invariant NKT cell subset.

Published in:

Journal of Clinical Investigation, 2014, v. 124, n. 9, p. 3725, doi. 10.1172/JCI72308

By:

Sag, Duygu;
Krause, Petra;
Hedrick, Catherine C.;
Kronenberg, Mitchell;
Wingender, Gerhard

Publication type:

Article

VEGF-C-dependent stimulation of lymphatic function ameliorates experimental inflammatory bowel disease.

Published in:

Journal of Clinical Investigation, 2014, v. 124, n. 9, p. 3863, doi. 10.1172/JCI72189

By:

D'Alessio, Silvia;
Correale, Carmen;
Tacconi, Carlotta;
Gandelli, Alessandro;
Pietrogrande, Giovanni;
Vetrano, Stefania;
Genua, Marco;
Arena, Vincenzo;
Spinelli, Antonino;
Peyrin-Biroulet, Laurent;
Fiocchi, Claudio;
Danese, Silvio

Publication type:

Article

Sexually dimorphic RB inactivation underlies mesenchymal glioblastoma prevalence in males.

Published in:

Journal of Clinical Investigation, 2014, v. 124, n. 9, p. 4123, doi. 10.1172/JCI71048

By:

Tao Sun;
Warrington, Nicole M.;
Jingqin Luo;
Brooks, Michael D.;
Dahiya, Sonika;
Snyder, Steven C.;
Sengupta, Rajarshi;
Rubin, Joshua B.

Publication type:

Article

Menin determines K-RAS proliferative outputs in endocrine cells.

Published in:

Journal of Clinical Investigation, 2014, v. 124, n. 9, p. 4093, doi. 10.1172/JCI69004

By:

Chamberlain, Chester E.;
Scheel, David W.;
McGlynn, Kathleen;
Kim, Hail;
Takeshi Miyatsuka;
Juehu Wang;
Vinh Nguyen;
Shuhong Zhao;
Mavropoulos, Anastasia;
Abraham, Aswin G.;
O'Neill, Eric;
Ku, Gregory M.;
Cobb, Melanie H.;
Martin, Gail R.;
German, Michael S.

Publication type:

Article

Ventromedial hypothalamus-specific Ptpn1 deletion exacerbates diet-induced obesity in female mice.

Published in:

Journal of Clinical Investigation, 2014, v. 124, n. 9, p. 3781, doi. 10.1172/JCI68585

By:

Chiappini, Franck;
Catalano, Karyn J.;
Lee, Jennifer;
Peroni, Odile D.;
Lynch, Jacqueline;
Dhaneshwar, Abha S.;
Wellenstein, Kerry;
Sontheimer, Alexandra;
Neel, Benjamin G.;
Kahn, Barbara B.

Publication type:

Article