Works matching IS 00219738 AND DT 2014 AND VI 124 AND IP 6

Results: 68
    1

    Epac1-dependent phospholamban phosphorylation mediates the cardiac response to stresses.

    Published in:
    2014
    By:
    • Okumura, Satoshi;
    • Fujita, Takayuki;
    • Cai, Wenqian;
    • Jin, Meihua;
    • Namekata, Iyuki;
    • Mototani, Yasumasa;
    • Jin, Huiling;
    • Ohnuki, Yoshiki;
    • Tsuneoka, Yayoi;
    • Kurotani, Reiko;
    • Suita, Kenji;
    • Kawakami, Yuko;
    • Hamaguchi, Shogo;
    • Abe, Takaya;
    • Kiyonari, Hiroshi;
    • Tsunematsu, Takashi;
    • Bai, Yunzhe;
    • Suzuki, Sayaka;
    • Hidaka, Yuko;
    • Umemura, Masanari
    Publication type:
    journal article
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    Type I IFN signaling in CD8- DCs impairs Th1-dependent malaria immunity.

    Published in:
    2014
    By:
    • Haque, Ashraful;
    • Best, Shannon E;
    • Montes de Oca, Marcela;
    • James, Kylie R;
    • Ammerdorffer, Anne;
    • Edwards, Chelsea L;
    • de Labastida Rivera, Fabian;
    • Amante, Fiona H;
    • Bunn, Patrick T;
    • Sheel, Meru;
    • Sebina, Ismail;
    • Koyama, Motoko;
    • Varelias, Antiopi;
    • Hertzog, Paul J;
    • Kalinke, Ulrich;
    • Gun, Sin Yee;
    • Rénia, Laurent;
    • Ruedl, Christiane;
    • MacDonald, Kelli P A;
    • Hill, Geoffrey R
    Publication type:
    journal article
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    Neural peptidase endothelin-converting enzyme 1 regulates endothelin 1-induced pruritus.

    Published in:
    2014
    By:
    • Kido-Nakahara, Makiko;
    • Buddenkotte, Jörg;
    • Kempkes, Cordula;
    • Ikoma, Akihiko;
    • Cevikbas, Ferda;
    • Akiyama, Tasuku;
    • Nunes, Frank;
    • Seeliger, Stephan;
    • Hasdemir, Burcu;
    • Mess, Christian;
    • Buhl, Timo;
    • Sulk, Mathias;
    • Müller, Frank-Ulrich;
    • Metze, Dieter;
    • Bunnett, Nigel W;
    • Bhargava, Aditi;
    • Carstens, Earl;
    • Furue, Masutaka;
    • Steinhoff, Martin
    Publication type:
    journal article
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    Epac1-dependent phospholamban phosphorylation mediates the cardiac response to stresses.

    Published in:
    Journal of Clinical Investigation, 2014, v. 124, n. 6, p. 2785, doi. 10.1172/JCI64784
    By:
    • Satoshi Okumura;
    • Takayuki Fujita;
    • Wenqian Cai;
    • Meihua Jin;
    • Iyuki Namekata;
    • Yasumasa Mototani;
    • Huiling Jin;
    • Yoshiki Ohnuki;
    • Yayoi Tsuneoka;
    • Reiko Kurotani;
    • Kenji Suita;
    • Yuko Kawakami;
    • Shogo Hamaguchi;
    • Takaya Abe;
    • Hiroshi Kiyonari;
    • Takashi Tsunematsu;
    • Yunzhe Bai;
    • Sayaka Suzuki;
    • Yuko Hidaka;
    • Masanari Umemura
    Publication type:
    Article
    23
    24

    Combined MEK and JAK inhibition abrogates murine myeloproliferative neoplasm.

    Published in:
    Journal of Clinical Investigation, 2014, v. 124, n. 6, p. 2762, doi. 10.1172/JCI74182
    By:
    • Guangyao Kong;
    • Wunderlich, Mark;
    • Yang, David;
    • Ranheim, Erik A.;
    • Young, Ken H.;
    • Jinyong Wang;
    • Yuan-I Chang;
    • Juan Du;
    • Yangang Liu;
    • Sin Ruow Tey;
    • Xinmin Zhang;
    • Juckett, Mark;
    • Mattison, Ryan;
    • Damnernsawad, Alisa;
    • Jingfang Zhang;
    • Mulloy, James C.;
    • Jing Zhang
    Publication type:
    Article
    25

    Elevated sphingosine-1-phosphate promotes sickling and sickle cell disease progression.

    Published in:
    Journal of Clinical Investigation, 2014, v. 124, n. 6, p. 2750, doi. 10.1172/JCI74604
    By:
    • Yujin Zhang;
    • Berka, Vladimir;
    • Anren Song;
    • Kaiqi Sun;
    • Wei Wang;
    • Weiru Zhang;
    • Chen Ning;
    • Chonghua Li;
    • Qibo Zhang;
    • Bogdanov, Mikhail;
    • Alexander, Danny C.;
    • Milburn, Michael V.;
    • Ahmed, Mostafa H.;
    • Han Lin;
    • Modupe Idowu;
    • Jun Zhang;
    • Kato, Gregory J.;
    • Abdulmalik, Osheiza Y.;
    • Wenzheng Zhang;
    • Dowhan, William
    Publication type:
    Article
    26

    Bicc1 is a genetic determinant of osteoblastogenesis and bone mineral density.

    Published in:
    Journal of Clinical Investigation, 2014, v. 124, n. 6, p. 2736, doi. 10.1172/JCI73072
    By:
    • Mesner, Larry D.;
    • Ray, Brianne;
    • Yi-Hsiang Hsu;
    • Manichaikul, Ani;
    • Lum, Eric;
    • Bryda, Elizabeth C.;
    • Rich, Stephen S.;
    • Rosen, Clifford J.;
    • Criqui, Michael H.;
    • Allison, Matthew;
    • Budoff, Matthew J.;
    • Clemens, Thomas L.;
    • Farber, Charles R.
    Publication type:
    Article
    27

    MicroRNA-7a regulates pancreatic β cell function.

    Published in:
    Journal of Clinical Investigation, 2014, v. 124, n. 6, p. 2722, doi. 10.1172/JCI73066
    By:
    • Latreille, Mathieu;
    • Hausser, Jean;
    • Stützer, Ina;
    • Quan Zhang;
    • Hastoy, Benoit;
    • Gargani, Sofia;
    • Kerr-Conte, Julie;
    • Pattou, Francois;
    • Zavolan, Mihaela;
    • Esguerra, Jonathan L. S.;
    • Eliasson, Lena;
    • Rülicke, Thomas;
    • Rorsman, Patrik;
    • Stoffel, Markus
    Publication type:
    Article
    28
    29

    ZEB1 sensitizes lung adenocarcinoma to metastasis suppression by PI3K antagonism.

    Published in:
    Journal of Clinical Investigation, 2014, v. 124, n. 6, p. 2696, doi. 10.1172/JCI72171
    By:
    • Yanan Yang;
    • Young-Ho Ahn;
    • Yulong Chen;
    • Xiaochao Tan;
    • Lixia Guo;
    • Gibbons, Don L.;
    • Ungewiss, Christin;
    • Peng, David H.;
    • Xin Liu;
    • Lin, Steven H.;
    • Thilaganathan, Nishan;
    • Wistuba, Ignacio I.;
    • Rodriguez-Canales, Jaime;
    • McLendon, Georgia;
    • Creighton, Chad J.;
    • Kurie, Jonathan M.
    Publication type:
    Article
    30

    Neural peptidase endothelin-converting enzyme 1 regulates endothelin 1 -- induced pruritus.

    Published in:
    Journal of Clinical Investigation, 2014, v. 124, n. 6, p. 2683, doi. 10.1172/JCI67323
    By:
    • Makiko Kido-Nakahara;
    • Buddenkotte, Jörg;
    • Kempkes, Cordula;
    • Akihiko Ikoma;
    • Cevikbas, Ferda;
    • Tasuku Akiyama;
    • Nunes, Frank;
    • Seeliger, Stephan;
    • Hasdemir, Burcu;
    • Mess, Christian;
    • Buhl, Timo;
    • Sulk, Mathias;
    • Müller, Frank-Ulrich;
    • Metze, Dieter;
    • Bunnett, Nigel W.;
    • Bhargava, Aditi;
    • Carstens, Earl;
    • Masutaka Furue;
    • Steinhoff, Martin
    Publication type:
    Article
    31

    Targeting CD137 enhances the efficacy of cetuximab.

    Published in:
    Journal of Clinical Investigation, 2014, v. 124, n. 6, p. 2668, doi. 10.1172/JCI73014
    By:
    • Kohrt, Holbrook E.;
    • Colevas, A. Dimitrios;
    • Houot, Roch;
    • Weiskopf, Kipp;
    • Goldstein, Matthew J.;
    • Lund, Peder;
    • Mueller, Antonia;
    • Sagiv-Barfi, Idit;
    • Marabelle, Aurelien;
    • Lira, Ruth;
    • Troutner, Emily;
    • Richards, Lori;
    • Rajapaska, Amanda;
    • Hebb, Jonathan;
    • Chester, Cariad;
    • Waller, Erin;
    • Ostashko, Anton;
    • Wen-Kai Weng;
    • Lieping Chen;
    • Czerwinski, Debra
    Publication type:
    Article
    32

    MicroRNA-486--dependent modulation of DOCK3/PTEN/AKT signaling pathways improves muscular dystrophy--associated symptoms.

    Published in:
    Journal of Clinical Investigation, 2014, v. 124, n. 6, p. 2651, doi. 10.1172/JCI73579
    By:
    • Alexander, Matthew S.;
    • Casar, Juan Carlos;
    • Motohashi, Norio;
    • Vieira, Natássia M.;
    • Eisenberg, Iris;
    • Marshall, Jamie L.;
    • Gasperini, Molly J.;
    • Lek, Angela;
    • Myers, Jennifer A.;
    • Estrella, Elicia A.;
    • Kang, Peter B.;
    • Shapiro, Frederic;
    • Rahimov, Fedik;
    • Kawahara, Genri;
    • Widrick, Jeffrey J.;
    • Kunkel, Louis M.
    Publication type:
    Article
    33

    The tumor suppressor folliculin regulates AMPK-dependent metabolic transformation.

    Published in:
    Journal of Clinical Investigation, 2014, v. 124, n. 6, p. 2640, doi. 10.1172/JCI71749
    By:
    • Ming Yan;
    • Gingras, Marie-Claude;
    • Dunlop, Elaine A.;
    • Nouët, Yann;
    • Dupuy, Fanny;
    • Jalali, Zahra;
    • Possik, Elite;
    • Coull, Barry J.;
    • Kharitidi, Dmitri;
    • Bondo Dydensborg, Anders;
    • Faubert, Brandon;
    • Kamps, Miriam;
    • Sabourin, Sylvie;
    • Preston, Rachael S.;
    • Davies, David Mark;
    • Roughead, Taren;
    • Chotard, Laëtitia;
    • van Steensel, Maurice A. M.;
    • Jones, Russell;
    • Tee, Andrew R.
    Publication type:
    Article
    34

    ER stress regulates myeloid-derived suppressor cell fate through TRAIL-R--mediated apoptosis.

    Published in:
    Journal of Clinical Investigation, 2014, v. 124, n. 6, p. 2626, doi. 10.1172/JCI74056
    By:
    • Condamine, Thomas;
    • Kumar, Vinit;
    • Ramachandran, Indu R.;
    • Je-In Youn;
    • Celis, Esteban;
    • Finnberg, Niklas;
    • El-Deiry, Wafik S.;
    • Winograd, Rafael;
    • Vonderheide, Robert H.;
    • English, Nickolas R.;
    • Knight, Stella C.;
    • Yagita, Hideo;
    • McCaffrey, Judith C.;
    • Antonia, Scott;
    • Hockstein, Neil;
    • Witt, Robert;
    • Masters, Gregory;
    • Bauer, Thomas;
    • Gabrilovich, Dmitry I.
    Publication type:
    Article
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    Vaccine-induced myeloid cell population dampens protective immunity to SIV.

    Published in:
    Journal of Clinical Investigation, 2014, v. 124, n. 6, p. 2538, doi. 10.1172/JCI73518
    By:
    • Yongjun Sui;
    • Hogg, Alison;
    • Yichuan Wang;
    • Frey, Blake;
    • Huifeng Yu;
    • Zheng Xia;
    • Venzon, David;
    • McKinnon, Katherine;
    • Smedley, Jeremy;
    • Gathuka, Mercy;
    • Klinman, Dennis;
    • Keele, Brandon F.;
    • Langermann, Sol;
    • Liu, Linda;
    • Franchini, Genoveffa;
    • Berzofsky, Jay A.
    Publication type:
    Article
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    Type I IFN signaling in CD8<sup>-</sup> DCs impairs Th1-dependent malaria immunity.

    Published in:
    Journal of Clinical Investigation, 2014, v. 124, n. 6, p. 2483, doi. 10.1172/JCI70698
    By:
    • Haque, Ashraful;
    • Best, Shannon E.;
    • de Oca, Marcela Montes;
    • James, Kylie R.;
    • Ammerdorffer, Anne;
    • Edwards, Chelsea L.;
    • de Labastida Rivera, Fabian;
    • Amante, Fiona H.;
    • Bunn, Patrick T.;
    • Sheel, Meru;
    • Sebina, Ismail;
    • Motoko Koyama;
    • Varelias, Antiopi;
    • Hertzog, Paul J.;
    • Kalinke, Ulrich;
    • Sin Yee Gun;
    • Rénia, Laurent;
    • Ruedl, Christiane;
    • MacDonald, Kelli P. A.;
    • Hill, Geoffrey R.
    Publication type:
    Article
    46
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    PDE5 inhibitor efficacy is estrogen dependent in female heart disease.

    Published in:
    Journal of Clinical Investigation, 2014, v. 124, n. 6, p. 2464, doi. 10.1172/JCI70731
    By:
    • Hideyuki Sasaki;
    • Takahiro Nagayama;
    • Blanton, Robert M.;
    • Kinya Seo;
    • Manling Zhang;
    • Guangshuo Zhu;
    • Lee, Dong I.;
    • Djahida Bedja;
    • Hsu, Steven;
    • Osamu Tsukamoto;
    • Seiji Takashima;
    • Masafumi Kitakaze;
    • Mendelsohn, Michael E.;
    • Karas, Richard H.;
    • Kass, David A.;
    • Eiki Takimoto
    Publication type:
    Article
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